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PE20110849A1 - Composicion estabilizada para el tratamiento de la psoriasis - Google Patents

Composicion estabilizada para el tratamiento de la psoriasis

Info

Publication number
PE20110849A1
PE20110849A1 PE2011000834A PE2011000834A PE20110849A1 PE 20110849 A1 PE20110849 A1 PE 20110849A1 PE 2011000834 A PE2011000834 A PE 2011000834A PE 2011000834 A PE2011000834 A PE 2011000834A PE 20110849 A1 PE20110849 A1 PE 20110849A1
Authority
PE
Peru
Prior art keywords
concentration
weight
psoriasis
treatment
refers
Prior art date
Application number
PE2011000834A
Other languages
English (en)
Inventor
William Shifeng Wei
Yiping Wang
Jianzhen Pan
Sung Hi Jo
Original Assignee
Nexmed Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexmed Holdings Inc filed Critical Nexmed Holdings Inc
Publication of PE20110849A1 publication Critical patent/PE20110849A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A UNA FORMULACION FARMACEUTICA QUE CONTIENE: (a) COMPUESTO DE VITAMINA D TAL COMO CALCIPOTRIENO PRESENTE A UNA CONCENTRACION DE 0.005% EN PESO (b) CORTICOSTEROIDES SELECCIONADOS DE CLOBETASOL PROPIONATO Y BETAMETASONA DIPROPIONATO PRESENTES EN UNA CONCENTRACION DE 0.05-0.064% EN PESO RESPECTIVAMENTE (c) N,N-DI(C1-C8)ALQUILAMINO SUSTITUIDO, ESTER ALQUIL (C4-C18)-CARBOXILICOL(C2-C18) TAL COMO DODECIL 2-(N,N-DIMETILAMINO)-PROPIONATO (DDAIP) A UN CONCENTRACION DE 1% EN PESO EN UN PORTADOR DE PETROLATO BLANCO Y QUE CONTIENE OPCIONALMENTE ACEITE MINERAL A UNA CONCENTRACION DE 3% EN PESO, TOCOFEROL A UNA CONCENTRACION DE 0.0002% EN PESO. SE REFIERE TAMBIEN A LA FORMULACION DE UN UNGUENTO NO ACUOSO DE ALMACENAMIENTO ESTABLE UTIL EN EL TRATAMIENTO DE PSORIASIS
PE2011000834A 2008-10-03 2009-10-02 Composicion estabilizada para el tratamiento de la psoriasis PE20110849A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19512608P 2008-10-03 2008-10-03

Publications (1)

Publication Number Publication Date
PE20110849A1 true PE20110849A1 (es) 2011-12-02

Family

ID=42073781

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2011000834A PE20110849A1 (es) 2008-10-03 2009-10-02 Composicion estabilizada para el tratamiento de la psoriasis

Country Status (18)

Country Link
US (2) US9220701B2 (es)
EP (1) EP2343978A4 (es)
JP (1) JP5667060B2 (es)
KR (1) KR20110067145A (es)
CN (1) CN102202509A (es)
AU (1) AU2009300331A1 (es)
BR (1) BRPI0920728A2 (es)
CA (1) CA2739376A1 (es)
CL (1) CL2011000722A1 (es)
CR (1) CR20110225A (es)
EC (1) ECSP11011022A (es)
IL (1) IL212062A0 (es)
MX (1) MX2011003568A (es)
NZ (1) NZ592300A (es)
PE (1) PE20110849A1 (es)
RU (1) RU2526162C2 (es)
WO (1) WO2010039251A1 (es)
ZA (1) ZA201103061B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5667060B2 (ja) * 2008-10-03 2015-02-12 ネクスメツド・ホールデイングス・インコーポレイテツド 乾癬を治療するための安定化組成物
US8809307B2 (en) * 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
WO2014028780A2 (en) * 2012-08-15 2014-02-20 Nexmed Holdings, Inc. Antifungal compounds and methods of use
CN105784902A (zh) * 2016-03-11 2016-07-20 重庆华邦制药有限公司 低浓度丁酸氯倍他松的检测方法
EP3456314A1 (en) 2017-09-14 2019-03-20 Tiofarma B.V. Topical formulation comprising 17-ketolic corticosteroid
WO2020044223A1 (en) * 2018-08-28 2020-03-05 Glenmark Pharmaceuticals Limited Container system and pharmaceutical foam composition comprising betamethasone

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980378A (en) * 1988-06-01 1990-12-25 Odontex, Inc. Biodegradable absorption enhancers
US6414028B1 (en) 1997-11-05 2002-07-02 Nexmed Holdings, Inc. Topical compositions containing prostaglandin E1
US6046244A (en) 1997-11-05 2000-04-04 Nexmed Holdings, Inc. Topical compositions for prostaglandin E1 delivery
US8263580B2 (en) * 1998-09-11 2012-09-11 Stiefel Research Australia Pty Ltd Vitamin formulation
HRP20010309B1 (en) 1998-12-23 2005-06-30 Idea Ag Improved formulation for topical non-invasive application in vivo
SK287653B6 (sk) 1999-04-23 2011-05-06 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Nevodná farmaceutická kompozícia na dermálne použitie
RU2361594C2 (ru) 2002-12-17 2009-07-20 Галдерма Са Фармацевтические композиции, включающие комбинацию кальцитриола и клобетазола пропионат
AU2004224326B2 (en) 2003-03-21 2010-04-22 Nexmed Holdings, Inc. Antifungal nail coat and method of use
US20080069779A1 (en) * 2003-08-04 2008-03-20 Foamix Ltd. Foamable vehicle and vitamin and flavonoid pharmaceutical compositions thereof
FR2871696B1 (fr) * 2004-06-17 2006-11-10 Galderma Sa Composition topique pour le traitement du psoriasis
US20060057075A1 (en) * 2004-08-02 2006-03-16 Moshe Arkin Pharmaceutical and cosmeceutical wash-off mousse shampoo compositions, processes for preparing the same and uses thereof
CN101378729B (zh) 2005-12-14 2013-09-11 扎尔斯制药公司 治疗皮肤症状的制剂和方法
US7560489B2 (en) * 2006-10-11 2009-07-14 Nexmed Holdings, Inc. Stabilized prostaglandin E composition
JP5667060B2 (ja) * 2008-10-03 2015-02-12 ネクスメツド・ホールデイングス・インコーポレイテツド 乾癬を治療するための安定化組成物

Also Published As

Publication number Publication date
RU2011117230A (ru) 2012-11-10
RU2526162C2 (ru) 2014-08-20
EP2343978A1 (en) 2011-07-20
IL212062A0 (en) 2011-06-30
JP5667060B2 (ja) 2015-02-12
ZA201103061B (en) 2012-04-25
BRPI0920728A2 (pt) 2015-08-18
CR20110225A (es) 2011-07-18
MX2011003568A (es) 2011-06-09
US9220701B2 (en) 2015-12-29
WO2010039251A1 (en) 2010-04-08
EP2343978A4 (en) 2013-11-27
CN102202509A (zh) 2011-09-28
JP2012504607A (ja) 2012-02-23
US20110237558A1 (en) 2011-09-29
CA2739376A1 (en) 2010-04-08
CL2011000722A1 (es) 2012-01-20
KR20110067145A (ko) 2011-06-21
AU2009300331A1 (en) 2010-04-08
NZ592300A (en) 2013-01-25
US20160067266A1 (en) 2016-03-10
ECSP11011022A (es) 2011-06-30

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