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PE20091836A1 - FORMULATIONS FOR THE EAR TO TREAT OTIC DISEASES AND CONDITIONS - Google Patents

FORMULATIONS FOR THE EAR TO TREAT OTIC DISEASES AND CONDITIONS

Info

Publication number
PE20091836A1
PE20091836A1 PE2009000550A PE2009000550A PE20091836A1 PE 20091836 A1 PE20091836 A1 PE 20091836A1 PE 2009000550 A PE2009000550 A PE 2009000550A PE 2009000550 A PE2009000550 A PE 2009000550A PE 20091836 A1 PE20091836 A1 PE 20091836A1
Authority
PE
Peru
Prior art keywords
agent
ear
formulations
conditions
tnf
Prior art date
Application number
PE2009000550A
Other languages
Spanish (es)
Inventor
Jay Lichter
Benedikt Vollrath
Andrew M Trammel
Sergio G Duron
Fabrice Piu
Luis A Dellamary
Qiang Ye
Carl Lebel
Jeffrey P Harris
Original Assignee
Otonomy Inc
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otonomy Inc, Univ California filed Critical Otonomy Inc
Publication of PE20091836A1 publication Critical patent/PE20091836A1/en

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  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

REFERIDA A UNA FORMULACION FARMACEUTICA QUE COMPRENDE: a) DE 0,2% A 6% EN PESO DE UN AGENTE INMUNOMODULADOR TAL COMO UN AGENTE ANTI-TNF, UN INHIBIDOR DE INTERLEUCINA, IKK, CALCINEURINA, ENZIMA QUE CUBRE TNF-a O DEL RECEPTOR SIMILAR A TOLL, b) DE 16% A 21% EN PESO DE UN COMPOLIMERO DE TRIBLOQUE POLIETILENO-POLIOXIPROPILENO BIODEGRADABLE, c) AGUA ESTERIL AMORTIGUADA. ADEMAS, COMPRENDE UN MUCOADHESIVO, UN INTENSIFICADOR DE PENETRACION, UN TINTE, UN AGENTE ESPESANTE TAL COMO CARBOXIMETIL CELULOSA, UN AGENTE TERAPEUTICO ADICIONAL TAL COMO UNA GAMA-GLOBULINA, UN ANTIBIOTICO, UN ANTI-EMETICO, ENTRE OTROS. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE TRANSTORNOS OTICOSREFERRING TO A PHARMACEUTICAL FORMULATION THAT INCLUDES: a) FROM 0.2% TO 6% BY WEIGHT OF AN IMMUNOMODULATING AGENT SUCH AS AN ANTI-TNF AGENT, AN INHIBITOR OF INTERLEUKIN, IKK, CALCINEURIN, ENZYME COVERING TNF-a OR OF THE RECEPTOR SIMILAR TO TOLL, b) FROM 16% TO 21% BY WEIGHT OF A BIODEGRADABLE POLYETHYLENE-POLYOXYPROPYLENE TRIBLOCK COMPOLIMER, c) STERILE CUSHIONED WATER. IN ADDITION, IT INCLUDES A MUCOADHESIVE, A PENETRATION ENHANCER, A DYE, A THICKENING AGENT SUCH AS CARBOXIMETHYL CELLULOSE, AN ADDITIONAL THERAPEUTIC AGENT SUCH AS A GLOBULIN-RANGE, AN ANTIBIOTIC, AN ANTI-ENTHETIC. SUCH COMPOSITION IS USEFUL IN THE TREATMENT OF OTIC DISORDERS

PE2009000550A 2008-04-21 2009-04-21 FORMULATIONS FOR THE EAR TO TREAT OTIC DISEASES AND CONDITIONS PE20091836A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4654308P 2008-04-21 2008-04-21

Publications (1)

Publication Number Publication Date
PE20091836A1 true PE20091836A1 (en) 2009-12-18

Family

ID=41665349

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2009000550A PE20091836A1 (en) 2008-04-21 2009-04-21 FORMULATIONS FOR THE EAR TO TREAT OTIC DISEASES AND CONDITIONS

Country Status (5)

Country Link
AR (1) AR071388A1 (en)
CL (1) CL2009000956A1 (en)
PE (1) PE20091836A1 (en)
TW (1) TWI412370B (en)
UY (1) UY31779A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI485145B (en) 2012-10-26 2015-05-21 Ind Tech Res Inst P-type organic semiconductor materials and optoelectronic components

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995004533A2 (en) * 1993-08-04 1995-02-16 Andrulis Pharmaceuticals Corporation Treatment of rheumatoid arthritis with thalidomide alone or in combination with other anti-inflammatory agents
AU2001251011A1 (en) * 2000-03-27 2001-10-08 The General Hospital Corporation Treatments for immune-mediated ear disorders
US20070021352A1 (en) * 2005-07-20 2007-01-25 Cypress Bioscience, Inc. Prevention and treatment of hearing disorders

Also Published As

Publication number Publication date
TW201004633A (en) 2010-02-01
UY31779A (en) 2009-12-14
TWI412370B (en) 2013-10-21
CL2009000956A1 (en) 2011-02-18
AR071388A1 (en) 2010-06-16

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