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PE20081198A1 - COMBINATION OF ACTIVE SUBSTANCES - Google Patents

COMBINATION OF ACTIVE SUBSTANCES

Info

Publication number
PE20081198A1
PE20081198A1 PE2007001687A PE2007001687A PE20081198A1 PE 20081198 A1 PE20081198 A1 PE 20081198A1 PE 2007001687 A PE2007001687 A PE 2007001687A PE 2007001687 A PE2007001687 A PE 2007001687A PE 20081198 A1 PE20081198 A1 PE 20081198A1
Authority
PE
Peru
Prior art keywords
alkyl
combination
formula
active substances
pirazol
Prior art date
Application number
PE2007001687A
Other languages
Spanish (es)
Inventor
Cabanas Carlos Ramon Trullas
Alonso Oscar Jimenez
Arjona Jordi Corber
Costa David Panyella
Capa Olga Gorchis
Original Assignee
Isdin Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isdin Sa filed Critical Isdin Sa
Publication of PE20081198A1 publication Critical patent/PE20081198A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4966—Triazines or their condensed derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

SE REFIERE A UNA COMBINACION DE DOS SUSTANCIAS ACTIVAS UV- ABSORBENTES: 1) LA SUSTANCIA ACTIVA UV-ABSORBENTE (A) ES UN COMPUESTO DE PIRROLTRIAZINA DE FORMULA (I) QUE SE ENCUENTRA EN UNA CANTIDAD DE 0,01% A 30% EN PESO DE LA COMPOSICION Y DONDE n ES DE 0 A 4; R1 ES H, ALQUILO(C1-C3) O FENILO SUSTITUIDO CON R2'R3'; R2, R2', R3 Y R3' SON CADA UNO H, HALOGENO, OH, ALQUILO(C1-C3), ENTRE OTROS; R4 Y R5 SON CADA UNO H, ALQUILO(C1-C4) O ARILO; A1 ES UN RADICAL DE FORMULA (II), (III), ENTRE OTROS; A2 ES UN RADICAL DE FORMULA (II) O (V), EN DONDE R6 ES H, ALQUILO(C1-C6) U OH; R7 ES H, CICLOALQUILO(C3-C6), ENTRE OTROS; R8 Y R9 SON CADA UNO H, -C(=O)-(C1-C18), ENTRE OTROS; R10 ES H O SO3M, DONDE M ES H, Na O K; 2) LA SUSTANCIA (B) ES UN DERIVADO DEL ACIDO ACRILICO, DE AMINOBENZAMIDAS, DE BENZIMIDAZOLICOS, ENTRE OTROS, TALES COMO 2,4-BIS(2,4-DIHIDROXIFENIL)-6-(1-METILO-1H-PIRAZOL-5-IL)-1,3,5-TRIAZINA, 2,4-BIS{[4-(2-ETILHEXILOXI)-2-HIDROXI]FENIL}-6-(1-METILO-1H-PIRAZOL-5-IL)-1,3,5-TRIAZINA, ENTRE OTROS, QUE SE ENCUENTRA EN UNA CANTIDAD DE 0,01% A 30% EN PESO DE LA COMPOSICION. DICHA COMBINACION SE ENCUENTRA EN FORMA MICRONIZADA Y ABSORBE EL 50% DE LA RADIACION UV TOTAL EN UN RANGO DE LONGITUD DE ONDA DE 290 A 400nm SIENDO UTIL PARA LA PROTECCION DE LA PIEL CONTRA LA RADIACION ULTRAVIOLETA, COMO FOTOESTABILIZANTES ADITIVOS EN POLIMEROS O COMO UN COMPONENTE EN FIBRAS TEXTILESIT REFERS TO A COMBINATION OF TWO UV-ABSORBING ACTIVE SUBSTANCES: 1) THE UV-ABSORBING ACTIVE SUBSTANCE (A) IS A PYRROLTRIAZINE COMPOUND OF FORMULA (I) WHICH IS IN AN AMOUNT OF 0.01% TO 30% BY WEIGHT OF THE COMPOSITION AND WHERE n IS FROM 0 TO 4; R1 IS H, (C1-C3) ALKYL OR PHENYL SUBSTITUTED WITH R2'R3 '; R2, R2 ', R3 AND R3' ARE EACH H, HALOGEN, OH, ALKYL (C1-C3), AMONG OTHERS; R4 AND R5 ARE EACH H, ALKYL (C1-C4) OR ARYL; A1 IS A RADICAL OF FORMULA (II), (III), AMONG OTHERS; A2 IS A RADICAL OF FORMULA (II) O (V), WHERE R6 IS H, ALKYL (C1-C6) OR OH; R7 IS H, CYCLOALKYL (C3-C6), AMONG OTHERS; R8 AND R9 ARE EACH H, -C (= O) - (C1-C18), AMONG OTHERS; R10 IS H O SO3M, WHERE M IS H, Na O K; 2) THE SUBSTANCE (B) IS A DERIVATIVE OF ACRYLIC ACID, AMINOBENZAMIDES, BENZIMIDAZOLICOS, AMONG OTHERS, SUCH AS 2,4-BIS (2,4-DIHYDROXYPHENIL) -6- (1-METHYL-1H-PIRAZOL-5 -IL) -1,3,5-TRIAZINE, 2,4-BIS {[4- (2-ETHYLHEXYLOXY) -2-HYDROXY] PHENYL} -6- (1-METHYL-1H-PIRAZOL-5-IL) - 1,3,5-TRIAZINE, AMONG OTHERS, WHICH IS IN A QUANTITY OF 0.01% TO 30% BY WEIGHT OF THE COMPOSITION. SUCH COMBINATION IS IN A MICRONIZED FORM AND ABSORBS 50% OF THE TOTAL UV RADIATION IN A WAVE LENGTH RANGE OF 290 TO 400nm, BEING USEFUL FOR THE PROTECTION OF THE SKIN AGAINST ULTRAVIOLET RADIATION, AS A PHOTOSTABILIZER IN A POLYESTER ADDITIVE. IN TEXTILE FIBERS

PE2007001687A 2006-12-04 2007-11-30 COMBINATION OF ACTIVE SUBSTANCES PE20081198A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06025059 2006-12-04

Publications (1)

Publication Number Publication Date
PE20081198A1 true PE20081198A1 (en) 2008-09-18

Family

ID=37946487

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2007001687A PE20081198A1 (en) 2006-12-04 2007-11-30 COMBINATION OF ACTIVE SUBSTANCES

Country Status (4)

Country Link
AR (1) AR064132A1 (en)
CL (1) CL2007003465A1 (en)
PE (1) PE20081198A1 (en)
WO (1) WO2008067928A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2322159A1 (en) 2009-10-30 2011-05-18 Green Molecular, S.L. Use of pterostilbene (pter) as medicament for prevention and/or treatment of skin diseases, damages or injures or as cosmetic
BE1019432A3 (en) * 2010-07-23 2012-07-03 Auriga Internat USE OF ISOTHIOCYANATES AND DERIVATIVES FOR THE TREATMENT AND / OR PREVENTION OF LUCITES.
CN102993439A (en) * 2012-10-30 2013-03-27 无锡三幸高膜科技有限公司 Water-soluble polytriazine macromolecular material
CN107057125A (en) * 2017-05-18 2017-08-18 句容亿格纳米材料厂 Modified salicylic acid aligns the preparation and its application in anti-light pollution plastics of octyl phenyl ester

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3581002D1 (en) * 1984-06-22 1991-02-07 Ilford Ag HYDROXYPHENYLTRIAZINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A UV ABSORBER.
DE19543730A1 (en) * 1995-11-23 1997-05-28 Ciba Geigy Ag Until resorcinyl-triazines
CN100528847C (en) * 2002-03-12 2009-08-19 西巴特殊化学品控股有限公司 Uv absorber compositions comprising a hydroxyphenyltriazine compound
JP4671953B2 (en) * 2003-01-20 2011-04-20 チバ ホールディング インコーポレーテッド Triazine derivatives as UV absorbers
ES2264624B1 (en) * 2004-12-16 2007-11-01 Isdin, S.A. NEW DERIVATIVES OF TRIAZINE, AS WELL AS PROCEDURES FOR THEIR OBTAINING AND ITS USE AS PROTECTIVE AGENTS AGAINST UV RADIATION.

Also Published As

Publication number Publication date
WO2008067928A1 (en) 2008-06-12
CL2007003465A1 (en) 2009-03-27
AR064132A1 (en) 2009-03-11

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