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PE20081736A1 - Compuestos triciclicos, composiciones, y procedimientos - Google Patents

Compuestos triciclicos, composiciones, y procedimientos

Info

Publication number
PE20081736A1
PE20081736A1 PE2008000231A PE2008000231A PE20081736A1 PE 20081736 A1 PE20081736 A1 PE 20081736A1 PE 2008000231 A PE2008000231 A PE 2008000231A PE 2008000231 A PE2008000231 A PE 2008000231A PE 20081736 A1 PE20081736 A1 PE 20081736A1
Authority
PE
Peru
Prior art keywords
procedures
compositions
compounds
4betha
methylpyridin
Prior art date
Application number
PE2008000231A
Other languages
English (en)
Inventor
Hengmiao Cheng
Xiaohua Huang
Kevin Dewayne Jerome
Mark Gerard Obukowicz
Lisa Olson
Paul Vincent Rucker
Ronald Keith Weber
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PE20081736A1 publication Critical patent/PE20081736A1/es

Links

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    • C—CHEMISTRY; METALLURGY
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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
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  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
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  • Hematology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)

Abstract

SE REFIERE A UN COMPUESTO (4BETHAS,7R,8ALFAR)-4BETHA-BENCIL-7-HIDROXI-N-(2-METILPIRIDIN-3-IL)-7-(TRIFLUOROMETIL)-4BETHA,5,6,7,8,8ALFA,9,10-OCTAHIDROFENANTRENO-2-CARBOXAMIDA O (2R,4ALFAS,10ALFAR)-4-ALFA-BENCIL-7-((2-METILPIRIDIN-3-IL)-CARBAMOIL)-2-(TRIFLUOROMETIL)-1,2,3,4,4ALFA,9,10,10ALFA-OCTAHIDROFENANTRENO-2-IL DIHIDROGENO FOSFATO. REFERIDA ADEMAS A UNA COMPOSICION FARMACEUTICA Y UN PROCEDIMIENTO DE PREPRACION. DICHOS COMPUESTOS SON MODULADORES DEL RECEPTOR DE GLUCOCORTICOIDES UTILES EN EL TRATAMIENTO DE ASMA, DERMATITIS, ALZHEIMER, NEUROPATIA, ENTRE OTROS
PE2008000231A 2007-02-02 2008-01-31 Compuestos triciclicos, composiciones, y procedimientos PE20081736A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88798107P 2007-02-02 2007-02-02

Publications (1)

Publication Number Publication Date
PE20081736A1 true PE20081736A1 (es) 2008-11-28

Family

ID=39315208

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2008000231A PE20081736A1 (es) 2007-02-02 2008-01-31 Compuestos triciclicos, composiciones, y procedimientos
PE2008000234A PE20090113A1 (es) 2007-02-02 2008-02-01 Compuestos triciclicos como moduladores del receptor de glucocorticoides, composiciones y procedimientos

Family Applications After (1)

Application Number Title Priority Date Filing Date
PE2008000234A PE20090113A1 (es) 2007-02-02 2008-02-01 Compuestos triciclicos como moduladores del receptor de glucocorticoides, composiciones y procedimientos

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US (7) US7547714B2 (es)
EP (1) EP2114970B1 (es)
JP (1) JP4599462B2 (es)
KR (2) KR101107949B1 (es)
CN (2) CN101616925B (es)
AP (1) AP2455A (es)
AR (2) AR065134A1 (es)
AT (1) ATE518872T1 (es)
AU (1) AU2008211613B2 (es)
BR (1) BRPI0808634A2 (es)
CA (1) CA2676670C (es)
CL (2) CL2008000329A1 (es)
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CU (2) CU23848B1 (es)
CY (2) CY1110962T1 (es)
DK (1) DK2114970T3 (es)
DO (1) DOP2009000190A (es)
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GE (2) GEP20125404B (es)
GT (2) GT200900209A (es)
HN (2) HN2008000178A (es)
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MY (3) MY146087A (es)
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NZ (1) NZ578638A (es)
PE (2) PE20081736A1 (es)
PL (1) PL2114970T3 (es)
PT (2) PT2114970E (es)
RS (2) RS51970B (es)
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WO (1) WO2008093227A1 (es)
ZA (2) ZA200906064B (es)

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