PE20080984A1 - Aminometil-2-imidazoles - Google Patents

Aminometil-2-imidazoles

Info

Publication number: PE20080984A1
Authority: PE; Peru
Prior art keywords: phenyl; amine; pirimidin; ilmethyl; ilo
Prior art date: 2006-10-19

Application number

PE2007001406A

Other languages

English (en)

Spanish (es)

Inventor

Guido Galley

Annick Goergler

Katrin Groebke Zbinden

Roger Norcross

Henri Stalder

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-10-19

Filing date

2007-10-17

Publication date

2008-07-19

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38819769&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20080984(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2007-10-17 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2008-07-19 Publication of PE20080984A1 publication Critical patent/PE20080984A1/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Anesthesiology (AREA)
Child & Adolescent Psychology (AREA)
Psychology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Addiction (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PE2007001406A 2006-10-19 2007-10-17 Aminometil-2-imidazoles PE20080984A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP06122553		2006-10-19

Publications (1)

Publication Number	Publication Date
PE20080984A1 true PE20080984A1 (es)	2008-07-19

Family

ID=38819769

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PE2007001406A PE20080984A1 (es)	2006-10-19	2007-10-17	Aminometil-2-imidazoles

Country Status (21)

Country	Link
US (1)	US20080096906A1 (no)
EP (1)	EP2076496B1 (no)
JP (1)	JP5167265B2 (no)
KR (1)	KR101172940B1 (no)
CN (1)	CN101528709B (no)
AR (1)	AR063326A1 (no)
AT (1)	ATE462696T1 (no)
AU (1)	AU2007312389B2 (no)
BR (1)	BRPI0718059A2 (no)
CA (1)	CA2665255A1 (no)
CL (1)	CL2007002970A1 (no)
DE (1)	DE602007005671D1 (no)
ES (1)	ES2340223T3 (no)
IL (1)	IL197872A (no)
MX (1)	MX2009003887A (no)
NO (1)	NO20091480L (no)
PE (1)	PE20080984A1 (no)
RU (1)	RU2009112495A (no)
TW (1)	TW200835494A (no)
WO (1)	WO2008046756A1 (no)
ZA (1)	ZA200902279B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK1976828T3 (en)	2005-12-29	2017-03-06	Celtaxsys Inc	DIAMINE DERIVATIVES AS INhibitors of Leukotriene A4 HYDROLASE
CA2666762C (en)	2006-10-19	2014-12-30	F. Hoffmann-La Roche Ag	Aminomethyl-4-imidazoles
BRPI0717657A2 (pt) *	2006-10-19	2013-12-24	Hoffmann La Roche	Compostos, processo para a preparação de um composto, composição farmacêutica que o compreende, usos de compostos, métodos para o tratamento e profilaxia de diabetes, obesidade, distúrbios alimentares, displidemia e hipertensão e profilaxia de diabetes do tipo ii
CA2694362A1 (en) *	2007-07-27	2009-02-05	F. Hoffmann-La Roche Ag	2-azetidinemethaneamines and 2-pyrrolidinemethaneamines as taar-ligands
US8242153B2 (en) *	2008-07-24	2012-08-14	Hoffmann-La Roche Inc.	4,5-dihydro-oxazol-2YL derivatives
JP6527851B2 (ja)	2013-03-12	2019-06-05	セルタクシス，インコーポレイテッド	ロイコトリエンａ４加水分解酵素を阻害する方法
EP2968265A4 (en)	2013-03-14	2016-12-28	Celtaxsys Inc	INHIBITORS OF THE LEUKOTRIEN A4 HYDROLASE
AU2014239567B2 (en)	2013-03-14	2017-12-14	Celtaxsys, Inc.	Inhibitors of leukotriene A4 hydrolase
KR20150127245A (ko) *	2013-03-14	2015-11-16	켈탁시스, 인코퍼레이티드	류코트라이엔 a4 가수분해효소의 저해제
JP7386815B2 (ja)	2018-05-31	2023-11-27	セルタクシー、エルエルシー	呼吸器疾患患者の肺増悪を軽減する方法
CN115073273B (zh) *	2021-03-15	2024-09-17	中国医学科学院药物研究所	二苯烷类化合物及其制备方法、药物组合物和用途
EP4317164A4 (en) *	2021-03-29	2024-07-31	Shujing Biopharma Co., Ltd	Spiro-containing derivative, and preparation method therefor and use thereof

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US2457047A (en) *	1946-02-13	1948-12-21	Monsanto Chemicals	2-(2'-thenyl)-4, 5-dihydroimidazoles and process for making the same
US2778836A (en) *	1954-04-02	1957-01-22	Union Chimique Belge Sa	Substituted 2-methyl-delta2 imidazolines
US2744910A (en) *	1955-06-27	1956-05-08	Bristol Lab Inc	2-(ortho-benzylbenzyl)-imidazoline and acid addition salts
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US4665095A (en) *	1985-12-11	1987-05-12	Abbott Laboratories	Use of 2-[(3,5-dihalo-4-aminobenzyl)]imidazolines to stimulate alpha-1 adrenergic receptors and to treat nasal congestion
GB9425211D0 (en) *	1994-12-14	1995-02-15	Ucb Sa	Substituted 1H-imidazoles
US5610174A (en) *	1995-06-02	1997-03-11	Synaptic Pharmaceutical Corporation	Use of α1A -selective adrenoceptor agonists for the treatment of urinary incontinence
US5969137A (en) *	1996-09-19	1999-10-19	Virginia Commonwealth University	Benzylamidine derivatives with serotonin receptor binding activity
US5866579A (en) *	1997-04-11	1999-02-02	Synaptic Pharmaceutical Corporation	Imidazole and imidazoline derivatives and uses thereof
CA2328973A1 (en) *	1998-04-23	1999-10-28	Akio Ojida	Naphthalene derivatives, their production and use
IL147921A0 (en) *	2002-01-31	2002-08-14	Abdulrazik Mohammad	A method for treating central nervous system disorders by ocular dosing
KR100492252B1 (ko) *	2002-08-09	2005-05-30	한국화학연구원	이미다졸을 포함하는 이차아민으로 치환된 벤조피란유도체 및 그의 제조방법
US20090209422A1 (en) *	2005-05-03	2009-08-20	Bayer Cropscience Ag	Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives

2007
- 2007-10-09 CN CN2007800387578A patent/CN101528709B/zh not_active Expired - Fee Related
- 2007-10-09 AT AT07821037T patent/ATE462696T1/de active
- 2007-10-09 ES ES07821037T patent/ES2340223T3/es active Active
- 2007-10-09 EP EP07821037A patent/EP2076496B1/en not_active Not-in-force
- 2007-10-09 DE DE602007005671T patent/DE602007005671D1/de active Active
- 2007-10-09 RU RU2009112495/04A patent/RU2009112495A/ru not_active Application Discontinuation
- 2007-10-09 JP JP2009532766A patent/JP5167265B2/ja not_active Expired - Fee Related
- 2007-10-09 AU AU2007312389A patent/AU2007312389B2/en not_active Ceased
- 2007-10-09 CA CA002665255A patent/CA2665255A1/en not_active Abandoned
- 2007-10-09 WO PCT/EP2007/060664 patent/WO2008046756A1/en not_active Ceased
- 2007-10-09 BR BRPI0718059-4A patent/BRPI0718059A2/pt not_active IP Right Cessation
- 2007-10-09 MX MX2009003887A patent/MX2009003887A/es active IP Right Grant
- 2007-10-09 KR KR1020097007959A patent/KR101172940B1/ko not_active Expired - Fee Related
- 2007-10-15 US US11/872,192 patent/US20080096906A1/en not_active Abandoned
- 2007-10-17 AR ARP070104589A patent/AR063326A1/es not_active Application Discontinuation
- 2007-10-17 TW TW096138927A patent/TW200835494A/zh unknown
- 2007-10-17 PE PE2007001406A patent/PE20080984A1/es not_active Application Discontinuation
- 2007-10-17 CL CL200702970A patent/CL2007002970A1/es unknown
2009
- 2009-03-26 IL IL197872A patent/IL197872A/en not_active IP Right Cessation
- 2009-04-01 ZA ZA200902279A patent/ZA200902279B/xx unknown
- 2009-04-17 NO NO20091480A patent/NO20091480L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU2007312389A1 (en)	2008-04-24
CN101528709B (zh)	2012-02-01
JP5167265B2 (ja)	2013-03-21
ES2340223T3 (es)	2010-05-31
WO2008046756A1 (en)	2008-04-24
EP2076496A1 (en)	2009-07-08
CN101528709A (zh)	2009-09-09
RU2009112495A (ru)	2010-11-27
EP2076496B1 (en)	2010-03-31
US20080096906A1 (en)	2008-04-24
IL197872A (en)	2012-12-31
MX2009003887A (es)	2009-04-22
JP2010506874A (ja)	2010-03-04
AR063326A1 (es)	2009-01-21
DE602007005671D1 (de)	2010-05-12
KR101172940B1 (ko)	2012-08-10
IL197872A0 (en)	2009-12-24
BRPI0718059A2 (pt)	2013-11-05
CA2665255A1 (en)	2008-04-24
KR20090055640A (ko)	2009-06-02
TW200835494A (en)	2008-09-01
ZA200902279B (en)	2010-03-31
NO20091480L (no)	2009-04-30
ATE462696T1 (de)	2010-04-15
AU2007312389B2 (en)	2012-02-23
CL2007002970A1 (es)	2008-05-30

Publication	Publication Date	Title
PE20080984A1 (es)	2008-07-19	Aminometil-2-imidazoles
EA200700047A1 (ru)	2007-06-29	Новые алкильные производные в качестве метаботропных рецепторов глутамата
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PE20091068A1 (es)	2009-07-15	Compuestos pirrolo[3,2-d]pirimidina y su uso como inhibidores de quinasa pi3 y quinasa mtor
PE20141203A1 (es)	2014-10-01	Benzilindazoles sustituidos para uso como inhibidores de la quinasa bub1 en el tratamiento de enfermedades hiperproliferativas
PE20141943A1 (es)	2014-12-28	Antagonistas de trpv4
PE20110150A1 (es)	2011-03-07	Amidofenoxiindazoles como inhibidores de c-met
PE20160431A1 (es)	2016-06-02	Moduladores del receptor p2x3 y p2x2/3 de diaminopiridina para el tratamiento de la tos aguda, sub-aguda o cronica
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