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PE20070216A1 - Nuevas composiciones farmaceuticas que comprenden levetiracetam y proceso para su preparacion - Google Patents

Nuevas composiciones farmaceuticas que comprenden levetiracetam y proceso para su preparacion

Info

Publication number
PE20070216A1
PE20070216A1 PE2006000890A PE2006000890A PE20070216A1 PE 20070216 A1 PE20070216 A1 PE 20070216A1 PE 2006000890 A PE2006000890 A PE 2006000890A PE 2006000890 A PE2006000890 A PE 2006000890A PE 20070216 A1 PE20070216 A1 PE 20070216A1
Authority
PE
Peru
Prior art keywords
weight
preparation
pharmaceutical compositions
compositions including
levetiracetam
Prior art date
Application number
PE2006000890A
Other languages
English (en)
Inventor
Michel Deleers
Jean-Benoît Hubert
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36888840&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20070216(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of PE20070216A1 publication Critical patent/PE20070216A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA DE ADMINISTRACION ORAL QUE COMPRENDE: A) LEVETIRACETAM; B) 2-9% EN PESO DE DESINTEGRANTE TAL COMO CROSCARAMELOSA SODICA; C) 0-3% EN PESO DE AGENTE DESLIZANTE TAL COMO SILICE COLOIDAL ANHIDRA; D) 0,5-6% EN PESO DE AGLUTINANTE TAL COMO POLIETILENGLICOL 6000; E) 0-1% EN PESO DE LUBRICANTE TAL COMO ESTEARATO DE MAGNESIO. TAMBIEN COMPRENDE UN AGENTE DE RECUBRIMIENTO QUE COMPRENDE POLI (ALCOHOL VINILICO). REFERIDA TAMBIEN A UN PROCEDIMIENTO DE PREPARACION.DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE EPILEPSIA, DISCINASIA, MIGRANA, TRASTORNOS BIPOLARES, DOLOR CRONICO, ENTRE OTROS
PE2006000890A 2005-07-26 2006-07-24 Nuevas composiciones farmaceuticas que comprenden levetiracetam y proceso para su preparacion PE20070216A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05016189 2005-07-26
EP05016945 2005-08-04

Publications (1)

Publication Number Publication Date
PE20070216A1 true PE20070216A1 (es) 2007-03-27

Family

ID=36888840

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2010000095A PE20100265A1 (es) 2005-07-26 2006-07-24 Nuevas composiciones farmaceuticas que comprenden levetiracetam y proceso para su preparacion
PE2006000890A PE20070216A1 (es) 2005-07-26 2006-07-24 Nuevas composiciones farmaceuticas que comprenden levetiracetam y proceso para su preparacion

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PE2010000095A PE20100265A1 (es) 2005-07-26 2006-07-24 Nuevas composiciones farmaceuticas que comprenden levetiracetam y proceso para su preparacion

Country Status (25)

Country Link
US (1) US8802142B2 (es)
EP (1) EP1909764B1 (es)
JP (2) JP5183470B2 (es)
KR (1) KR20080030546A (es)
CN (1) CN101068534B (es)
AR (1) AR054581A1 (es)
AU (1) AU2006274263B2 (es)
BR (1) BRPI0606121A2 (es)
CA (1) CA2581831C (es)
CY (1) CY1115825T1 (es)
DK (1) DK1909764T3 (es)
EA (1) EA014961B1 (es)
ES (1) ES2524771T3 (es)
HR (1) HRP20141185T1 (es)
IL (1) IL182375A0 (es)
MX (1) MX2007004294A (es)
NO (1) NO20071667L (es)
NZ (1) NZ554157A (es)
PE (2) PE20100265A1 (es)
PL (1) PL1909764T3 (es)
PT (1) PT1909764E (es)
RS (1) RS53690B1 (es)
SI (1) SI1909764T1 (es)
TW (1) TW200738280A (es)
WO (1) WO2007012439A1 (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005325930B2 (en) 2005-01-27 2012-01-19 Alembic Limited Extended release formulation of Levetiracetam
CN101360493A (zh) * 2006-01-24 2009-02-04 特瓦制药工业有限公司 左乙拉西坦制剂和制备方法
FR2912056B1 (fr) * 2007-02-05 2009-12-18 Rd Pharmagal Composition a liberation prolongee de levetiracetam et procede de preparation
JP2010024156A (ja) * 2008-07-16 2010-02-04 Ucb Pharma Sa レベチラセタムを含む医薬組成物
DE102008059206A1 (de) * 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum
CN101422442A (zh) * 2008-12-09 2009-05-06 沈阳药科大学 左乙拉西坦渗透泵控释片及其制备方法
US20100172979A1 (en) * 2008-12-24 2010-07-08 Zhongshui Yu Controlled-release formulations
US20100159009A1 (en) * 2008-12-24 2010-06-24 Zhongshui Yu Controlled-release formulations
WO2010094535A1 (en) * 2009-01-29 2010-08-26 Ucb Pharma, S.A. Pharmaceutical compositions comprising 2-oxo-1-pyrrolidine derivatives
AU2010265863C1 (en) 2009-06-26 2012-11-01 Taris Biomedical Llc Implantable drug delivery devices and methods of making the same
CN102038657B (zh) * 2009-10-10 2015-04-15 浙江华海药业股份有限公司 左乙拉西坦片及其制备方法
EP2552447A4 (en) * 2010-03-29 2013-09-11 Hetero Research Foundation STABLE PHARMACEUTICAL COMPOSITION OF IMATINIB
TR201011148A1 (tr) 2010-12-30 2012-07-23 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Levetirasetam farmasötik bileşimleri.
CN109662961A (zh) * 2011-02-09 2019-04-23 约翰斯霍普金斯大学 用于改善认知功能的方法和组合物
CN102188420B (zh) * 2011-03-25 2013-04-10 华润赛科药业有限责任公司 一种左乙拉西坦的药物组合物及其制备方法
CN102895214B (zh) * 2012-10-25 2014-03-26 杭州朱养心药业有限公司 左乙拉西坦片剂的固体药物组合物
CN102871981B (zh) * 2012-10-25 2013-11-13 杭州朱养心药业有限公司 包含左乙拉西坦的片剂药物组合物
CN103127175B (zh) * 2013-02-22 2014-01-22 张晓光 一种抗癫痫药物及其制备方法
HK1216513A1 (zh) 2013-03-15 2016-11-18 阿普雷奇亚制药有限责任公司 包含左乙拉西坦的快速分散劑型
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
JP6433482B2 (ja) 2013-03-15 2018-12-05 エージンバイオ, インコーポレイテッド 認知機能を改善するための方法および組成物
EP2968237A4 (en) 2013-03-15 2016-08-31 Univ Johns Hopkins METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
US20170035733A1 (en) * 2013-11-29 2017-02-09 Ucb Pharma Gmbh Pharmaceutical composition comprising lacosamide and levetiracetam
CN104666263B (zh) * 2015-02-09 2017-07-11 海南华益泰康药业有限公司 一种含有左乙拉西坦的片剂及其制备方法
BR112017025031B1 (pt) 2015-05-22 2023-03-21 Agenebio, Inc Composições farmacêuticas de liberação prolongada de levetiracetam
JP6630229B2 (ja) * 2016-05-17 2020-01-15 エルメッド株式会社 レベチラセタム含有医薬組成物及びその製造方法
JP6422464B2 (ja) * 2016-05-19 2018-11-14 エルメッド エーザイ株式会社 レベチラセタム含有医薬組成物及びその製造方法、並びにレベチラセタム含有医薬組成物の崩壊及び溶出の少なくともいずれかの遅延防止方法、及びレベチラセタム含有医薬組成物の崩壊及び溶出の少なくともいずれかの遅延防止剤
CN107913258A (zh) * 2016-10-09 2018-04-17 北京阜康仁生物制药科技有限公司 一种左乙拉西坦缓释片及其制备方法
JP6326114B2 (ja) * 2016-11-01 2018-05-16 エルメッド エーザイ株式会社 レベチラセタム含有医薬組成物及びその製造方法、並びにレベチラセタム含有医薬組成物の崩壊及び溶出の少なくともいずれかの遅延防止方法、及びレベチラセタム含有医薬組成物の崩壊及び溶出の少なくともいずれかの遅延防止剤
JP7264711B2 (ja) * 2019-04-26 2023-04-25 東和薬品株式会社 レベチラセタム含有医薬組成物の製造方法
JP7575217B2 (ja) * 2019-08-09 2024-10-29 日本ジェネリック株式会社 レベチラセタムを含む錠剤
CN117838643A (zh) * 2023-12-29 2024-04-09 山东力诺制药有限公司 一种吡拉西坦片及其制备方法

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EP2601953A1 (en) 2003-05-23 2013-06-12 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and mood stabilizers for treating mood disorders
AU2005325930B2 (en) 2005-01-27 2012-01-19 Alembic Limited Extended release formulation of Levetiracetam

Also Published As

Publication number Publication date
NO20071667L (no) 2007-04-26
AU2006274263B2 (en) 2011-01-27
HK1109071A1 (en) 2008-05-30
MX2007004294A (es) 2008-03-11
ES2524771T3 (es) 2014-12-12
EA200700566A1 (ru) 2008-08-29
SI1909764T1 (sl) 2015-01-30
PE20100265A1 (es) 2010-04-21
PT1909764E (pt) 2014-12-18
KR20080030546A (ko) 2008-04-04
BRPI0606121A2 (pt) 2009-10-06
RS53690B1 (sr) 2015-04-30
CY1115825T1 (el) 2017-01-25
NZ554157A (en) 2010-12-24
EP1909764A1 (en) 2008-04-16
WO2007012439A1 (en) 2007-02-01
AU2006274263A1 (en) 2007-02-01
HRP20141185T1 (hr) 2015-01-30
JP2013018786A (ja) 2013-01-31
AR054581A1 (es) 2007-06-27
CN101068534A (zh) 2007-11-07
IL182375A0 (en) 2007-07-24
JP2009502835A (ja) 2009-01-29
US20080269316A1 (en) 2008-10-30
EA014961B1 (ru) 2011-04-29
DK1909764T3 (da) 2014-12-15
US8802142B2 (en) 2014-08-12
CA2581831C (en) 2013-11-12
EP1909764B1 (en) 2014-09-10
PL1909764T3 (pl) 2015-03-31
TW200738280A (en) 2007-10-16
CN101068534B (zh) 2011-09-07
CA2581831A1 (en) 2007-02-01
JP5183470B2 (ja) 2013-04-17

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