PE20061244A1 - Sistema terapeutico transdermico para la administracion de analgesicos - Google Patents
Sistema terapeutico transdermico para la administracion de analgesicosInfo
- Publication number
- PE20061244A1 PE20061244A1 PE2006000249A PE2006000249A PE20061244A1 PE 20061244 A1 PE20061244 A1 PE 20061244A1 PE 2006000249 A PE2006000249 A PE 2006000249A PE 2006000249 A PE2006000249 A PE 2006000249A PE 20061244 A1 PE20061244 A1 PE 20061244A1
- Authority
- PE
- Peru
- Prior art keywords
- layer
- analgesic
- weight
- adhesive layer
- refers
- Prior art date
Links
- 229940035676 analgesics Drugs 0.000 title 1
- 239000000730 antalgic agent Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 239000010410 layer Substances 0.000 abstract 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- 239000012790 adhesive layer Substances 0.000 abstract 3
- 230000000202 analgesic effect Effects 0.000 abstract 3
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
- NOOLISFMXDJSKH-KXUCPTDWSA-N (-)-Menthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O NOOLISFMXDJSKH-KXUCPTDWSA-N 0.000 abstract 1
- 208000006820 Arthralgia Diseases 0.000 abstract 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 abstract 1
- 206010019233 Headaches Diseases 0.000 abstract 1
- BRUQQQPBMZOVGD-XFKAJCMBSA-N Oxycodone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(OC)C2=C5[C@@]13CCN4C BRUQQQPBMZOVGD-XFKAJCMBSA-N 0.000 abstract 1
- 239000004820 Pressure-sensitive adhesive Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 abstract 1
- 229960001736 buprenorphine Drugs 0.000 abstract 1
- PJMPHNIQZUBGLI-UHFFFAOYSA-N fentanyl Chemical compound C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 PJMPHNIQZUBGLI-UHFFFAOYSA-N 0.000 abstract 1
- 229960002428 fentanyl Drugs 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 229940041616 menthol Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229960005181 morphine Drugs 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 229960002085 oxycodone Drugs 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229920000058 polyacrylate Polymers 0.000 abstract 1
- 229920001296 polysiloxane Polymers 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229940100640 transdermal system Drugs 0.000 abstract 1
- 208000009935 visceral pain Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A UN SISTEMA TRANSDERMICO QUE COMPRENDE A) UNA CAPA (T) DE SOPORTE QUE PRESENTA UN ESPESOR DE CAPA DE 5 HASTA 125um O DE 125 HASTA 2000um; B) UNA CAPA (K) ADHESIVA QUE LIMITA DIRECTAMENTE CON LA CAPA (T) DE SOPORTE, BASADA EN UNA SUSTANCIA ADHESIVA SENSIBLE A LA PRESION TAL COMO POLIACRILATOS, POLIISOBUTILOS Y SILICONAS QUE TIENE UN ESPESOR ENTRE 2,0um Y 5,0um Y QUE CONTIENE i) UN ANALGESICO TAL COMO BUPRENORFINA, FENTANILO, MORFINA, OXICODONA, ENTRE OTROS, QUE SE ENCUENTRA EN UNA CANTIDAD DE 0,1% A 25% EN PESO CON RESPECTO AL PESO DE LA CAPA (K) ADHESIVA; E ii) UN EXCIPIENTE PARA LA MEJORA DE LA PERMEACION TRANSDERMICA DEL ANALGESICO TAL COMO AMINAS, BASES INORGANICAS, PROPILENGLICOL, MENTOL, ENTRE OTROS; Y C) UNA CAPA (S) DE PROTECCION EXTRAIBLE. TAMBIEN SE REFIERE A UN PROCEDIMIENTO DE PREPARACION. DICHO SISTEMA LIBERA AL MENOS EL 50% EN PESO DEL ANALGESICO CONTENIDO EN LA CAPA (K) ADHESIVA EN UN TIEMPO DE 72 HORAS Y ES UTIL EN EL TRATAMIENTO DEL DOLOR NEUROPATICO, DOLOR VISCERAL, CEFALEAS, DOLORES ARTICULARES
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005011517A DE102005011517A1 (de) | 2005-03-10 | 2005-03-10 | Transdermales therapeutisches System zur Verabreichung von Analgetika |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20061244A1 true PE20061244A1 (es) | 2007-01-06 |
Family
ID=36514546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2006000249A PE20061244A1 (es) | 2005-03-10 | 2006-03-06 | Sistema terapeutico transdermico para la administracion de analgesicos |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20070298091A1 (es) |
| EP (1) | EP1858496B1 (es) |
| AR (1) | AR054012A1 (es) |
| AT (1) | ATE401870T1 (es) |
| DE (2) | DE102005011517A1 (es) |
| ES (1) | ES2311281T3 (es) |
| PE (1) | PE20061244A1 (es) |
| PL (1) | PL1858496T3 (es) |
| WO (1) | WO2006094961A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10146815B4 (de) | 2001-09-18 | 2005-05-04 | Ing. Erich Pfeiffer Gmbh | Spender für Medien |
| DE10356362A1 (de) | 2003-11-28 | 2005-06-23 | Grünenthal GmbH | Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie von Angststörungen |
| DE102006054733A1 (de) * | 2006-11-21 | 2008-05-29 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches Systems mit hoher Wirkstoffausnutzungsrate und Dosiergenauigkeit |
| US20100256197A1 (en) * | 2009-04-02 | 2010-10-07 | Silver Eagle Labs Nv, Llc | Nicotine Dissolving Film With Or Without Menthol |
| DE102011076653A1 (de) * | 2011-05-27 | 2012-11-29 | Acino Ag | Transdermales therapeutisches System enthaltend Buprenorphin und eine alpha-Hydroxysäure |
| US8515525B2 (en) * | 2011-08-16 | 2013-08-20 | Women's Imaging Solutions Enterprises Llc | Skin adhesive agent for mammography procedures |
| HUE035512T2 (en) * | 2012-07-16 | 2018-05-02 | Gruenenthal Gmbh | Pharmaceutical patch for transdermal administration of tapentadol |
| US11547676B2 (en) | 2012-12-28 | 2023-01-10 | Teikoku Seiyaku Co., Ltd. | Extended buprenorphine transdermal delivery compositions and methods for using the same |
| US20180235903A1 (en) * | 2015-03-13 | 2018-08-23 | Amneal Pharmaceuticals Llc | Fentanyl Transdermal Delivery System |
| GB201513442D0 (en) * | 2015-07-30 | 2015-09-16 | Euro Celtique Sa | Transdermal patch |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3900610A (en) * | 1973-04-09 | 1975-08-19 | Monsanto Co | Process of making a pressure sensitive adhesive article |
| JPS6059207B2 (ja) * | 1981-03-13 | 1985-12-24 | 日東電工株式会社 | 複合製剤の製法 |
| DE3315272C2 (de) * | 1983-04-27 | 1986-03-27 | Lohmann Gmbh & Co Kg, 5450 Neuwied | Pharmazeutisches Produkt und Verfahren zu seiner Herstellung |
| DE3315245A1 (de) * | 1983-04-27 | 1984-10-31 | Lohmann Gmbh & Co Kg, 5450 Neuwied | Pharmazeutisches produkt |
| DE69115445T2 (de) * | 1990-04-24 | 1996-06-20 | Teijin Ltd | Pflaster |
| US5429590A (en) * | 1992-12-01 | 1995-07-04 | Nitto Denko Corporation | Medical water-absorptive polymer and dressing for wound and medical bandage using the same |
| US6093419A (en) * | 1995-06-07 | 2000-07-25 | Lectec Corporation | Compliance verification method and device in compulsory drug administration |
| JP4659943B2 (ja) * | 2000-02-25 | 2011-03-30 | 帝三製薬株式会社 | 塩酸ブプレノルフィン含有貼付剤 |
| EP1323421A1 (en) * | 2001-12-20 | 2003-07-02 | Grünenthal GmbH | Use of buprenorphine for the manufacture of a transdermal delivery device for the treatment of urinary incontinence, especially urge incontinence |
-
2005
- 2005-03-10 DE DE102005011517A patent/DE102005011517A1/de not_active Withdrawn
-
2006
- 2006-03-06 EP EP06724947A patent/EP1858496B1/de not_active Revoked
- 2006-03-06 PE PE2006000249A patent/PE20061244A1/es not_active Application Discontinuation
- 2006-03-06 DE DE502006001195T patent/DE502006001195D1/de active Active
- 2006-03-06 AT AT06724947T patent/ATE401870T1/de active
- 2006-03-06 AR ARP060100843A patent/AR054012A1/es not_active Application Discontinuation
- 2006-03-06 WO PCT/EP2006/060484 patent/WO2006094961A1/de not_active Ceased
- 2006-03-06 PL PL06724947T patent/PL1858496T3/pl unknown
- 2006-03-06 ES ES06724947T patent/ES2311281T3/es active Active
-
2007
- 2007-09-07 US US11/851,645 patent/US20070298091A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006094961A1 (de) | 2006-09-14 |
| ES2311281T3 (es) | 2009-02-01 |
| ATE401870T1 (de) | 2008-08-15 |
| DE102005011517A1 (de) | 2006-09-21 |
| PL1858496T3 (pl) | 2009-01-30 |
| EP1858496A1 (de) | 2007-11-28 |
| AR054012A1 (es) | 2007-05-30 |
| EP1858496B1 (de) | 2008-07-23 |
| DE502006001195D1 (de) | 2008-09-04 |
| US20070298091A1 (en) | 2007-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |