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PE20050150A1 - Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo - Google Patents

Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo

Info

Publication number
PE20050150A1
PE20050150A1 PE2004000456A PE2004000456A PE20050150A1 PE 20050150 A1 PE20050150 A1 PE 20050150A1 PE 2004000456 A PE2004000456 A PE 2004000456A PE 2004000456 A PE2004000456 A PE 2004000456A PE 20050150 A1 PE20050150 A1 PE 20050150A1
Authority
PE
Peru
Prior art keywords
dosage form
pantoprazole
layer
salt
carma
Prior art date
Application number
PE2004000456A
Other languages
English (en)
Inventor
Rango Dietrich
Isabel Anstett
Hartmut Ney
Manfred Hartmann
Sabine Schafer-Preuss
Marc Schiller
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of PE20050150A1 publication Critical patent/PE20050150A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA FORMA DE DOSIFICACION PARA LA ADMINISTRACION ORAL DE LA SAL DE MAGNESIO DE (S)-PANTOPRAZOL 5-DIFLUOROMETOXI-2-[(3,4-DIMETOXI-2-PIRIDINIL)METILSULFINIL)-1H-BENZIMIDAZOLEN FORMA DE TABLETA CARACTERIZADA PORQUE ES UN FORMA DE DOSIFICACION DE LIBERACION RETARDADA QUE COMPRENDE UNA CAPA ENTERICA SOLUBLE EN CONDICIONES NEUTRAS O ALCALINAS Y AL MENOS UNA CAPA INTERMEDIA (CAPA DE SOBRECUBRIMIENTO).LA SAL ES (S)-PANTOPRAZOL MAGNESICO DIHIDRATO. LA TABLETA COMPRENDE: a) UN NUCLEO EN EL CUAL EL COMPUESTO ACTIVO O SU SAL SE ENCUENTRA MEZCLADO CON UN LIGANTE RELLENO SELECCIONADO DE POLIVINILPIRROLIDONA, HIDROXIPROPILMETILCELULOSA, MANITOL; b) UN AGENTE AUXILIAR PARA LA FORMACION DE TABLETAS; c) UN COMPUESTO INORGANICO BASICO; d) UNA CAPA INTERMEDIA INERTE SOLUBLE EN AGUA QUE RODEA AL NUCLEO; e) UNA CAPA EXTERIOR RESISTENTE AL JUGO GASTRICO. EL COMPUESTO ES UTIL PARA EL TRATAMIENTO DE ULCERA GASTRICA BENIGNA, REFLUJO GASTRO-ESOFAGICO, ULCERA DUODENAL
PE2004000456A 2003-05-08 2004-05-05 Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo PE20050150A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03010368 2003-05-08
EP04001759 2004-01-28

Publications (1)

Publication Number Publication Date
PE20050150A1 true PE20050150A1 (es) 2005-03-22

Family

ID=33436113

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2004000456A PE20050150A1 (es) 2003-05-08 2004-05-05 Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo

Country Status (11)

Country Link
US (2) US20060216346A1 (es)
EP (1) EP1624870B1 (es)
JP (1) JP4800926B2 (es)
AR (1) AR044265A1 (es)
AU (1) AU2004237364B2 (es)
CA (1) CA2524979C (es)
CL (1) CL2004000984A1 (es)
ES (1) ES2392687T3 (es)
PE (1) PE20050150A1 (es)
TW (1) TW200503785A (es)
WO (1) WO2004098577A2 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20050150A1 (es) 2003-05-08 2005-03-22 Altana Pharma Ag Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo
CL2004000983A1 (es) 2003-05-08 2005-03-04 Altana Pharma Ag Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y
NZ544608A (en) * 2003-07-17 2008-07-31 Reddys Lab Ltd Dr Pharmaceutical compositions having a swellable coating comprising prolamin
US20050147663A1 (en) * 2003-07-17 2005-07-07 Mohan Mailatur S. Method of treatment for improved bioavailability
TWI372066B (en) 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
PT1746980E (pt) 2004-05-07 2012-01-25 Nycomed Gmbh Forma de dosagem farmacêutica compreendendo granulados assim como o seu processo de fabrico
AU2007311493B2 (en) * 2006-10-17 2013-01-31 Ranbaxy Laboratories Limited Multiple unit tablet compositions of benzimidazole compounds
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
EP3522889A4 (en) * 2016-10-06 2020-05-27 Jubilant Generics Limited PHARMACEUTICAL COMPOSITION OF PANTOPRAZOLE WITH DELAYED RELEASE AND METHOD FOR THE PRODUCTION THEREOF
US11291654B2 (en) * 2018-09-13 2022-04-05 Syneurx International (Taiwan) Corp. Formulations of cycloserine compounds and applications thereof

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JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
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FI90544C (fi) 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
US5026560A (en) 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
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TW200503783A (en) * 2003-04-11 2005-02-01 Altana Pharma Ag Oral pharmaceutical preparation for proton pump antagonists
CL2004000983A1 (es) 2003-05-08 2005-03-04 Altana Pharma Ag Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y
PE20050150A1 (es) 2003-05-08 2005-03-22 Altana Pharma Ag Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo
TWI372066B (en) 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
PT1746980E (pt) 2004-05-07 2012-01-25 Nycomed Gmbh Forma de dosagem farmacêutica compreendendo granulados assim como o seu processo de fabrico
JP4563077B2 (ja) 2004-05-28 2010-10-13 株式会社ロッテ キャンディ及びその製造方法

Also Published As

Publication number Publication date
CA2524979A1 (en) 2004-11-18
CA2524979C (en) 2012-08-14
CL2004000984A1 (es) 2005-03-04
WO2004098577A2 (en) 2004-11-18
US20060216346A1 (en) 2006-09-28
TW200503785A (en) 2005-02-01
AU2004237364A1 (en) 2004-11-18
JP4800926B2 (ja) 2011-10-26
US20110171303A1 (en) 2011-07-14
AR044265A1 (es) 2005-09-07
AU2004237364B2 (en) 2010-02-18
JP2006525287A (ja) 2006-11-09
US8758817B2 (en) 2014-06-24
EP1624870B1 (en) 2012-08-08
ES2392687T3 (es) 2012-12-12
WO2004098577A3 (en) 2004-12-09
EP1624870A2 (en) 2006-02-15

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