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PE20050923A1 - Composicion solida que comprende un sensibilizador de insulina, un secretagogo de insulina y un ester de acidos grasos - Google Patents

Composicion solida que comprende un sensibilizador de insulina, un secretagogo de insulina y un ester de acidos grasos

Info

Publication number
PE20050923A1
PE20050923A1 PE2004001032A PE2004001032A PE20050923A1 PE 20050923 A1 PE20050923 A1 PE 20050923A1 PE 2004001032 A PE2004001032 A PE 2004001032A PE 2004001032 A PE2004001032 A PE 2004001032A PE 20050923 A1 PE20050923 A1 PE 20050923A1
Authority
PE
Peru
Prior art keywords
insulin
secretagog
solid composition
fatty acid
acid ester
Prior art date
Application number
PE2004001032A
Other languages
English (en)
Inventor
Kazuhiro Doken
Tetsuya Kawano
Hiroyoshi Koyama
Naoru Hamaguchi
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34543966&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20050923(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of PE20050923A1 publication Critical patent/PE20050923A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA COMPOSICION SOLIDA QUE COMPRENDE: A) UN SENSIBILIZADOR DE INSULINA TAL COMO PIOGLITAZONA; B) UN SECRETAGOGO DE INSULINA COMO GLIMERIPIDA Y C) UN ESTER DE ACIDOS GRASOS DE POLIOXIETILENO SORBITANO SELECCIONADO DE POLISORBATO 80. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA Y A UN PROCEDIMIENTO DE PREPARACION. DICHA COMPOSICION MEJORA LA DISOLUCION DEL SECRETAGOGO DE INSULINA UTIL EN EL TRATAMIENTO DE LA DIABETES
PE2004001032A 2003-10-31 2004-10-27 Composicion solida que comprende un sensibilizador de insulina, un secretagogo de insulina y un ester de acidos grasos PE20050923A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003371679 2003-10-31

Publications (1)

Publication Number Publication Date
PE20050923A1 true PE20050923A1 (es) 2005-12-26

Family

ID=34543966

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2004001032A PE20050923A1 (es) 2003-10-31 2004-10-27 Composicion solida que comprende un sensibilizador de insulina, un secretagogo de insulina y un ester de acidos grasos

Country Status (28)

Country Link
US (1) US7700128B2 (es)
EP (1) EP1677792B1 (es)
KR (2) KR20100012105A (es)
CN (1) CN1874774B (es)
AR (1) AR046210A1 (es)
AU (1) AU2004285354B2 (es)
BR (1) BRPI0414979A (es)
CA (1) CA2540225C (es)
CY (1) CY1117176T1 (es)
DK (1) DK1677792T3 (es)
ES (1) ES2556244T3 (es)
GE (1) GEP20084570B (es)
HR (1) HRP20151447T1 (es)
HU (1) HUE028576T2 (es)
IL (1) IL174201A (es)
JO (1) JO3106B1 (es)
MA (1) MA28116A1 (es)
MX (1) MXPA06004639A (es)
NO (1) NO340294B1 (es)
NZ (1) NZ546337A (es)
PE (1) PE20050923A1 (es)
PL (1) PL1677792T3 (es)
PT (1) PT1677792E (es)
RU (1) RU2359661C2 (es)
SI (1) SI1677792T1 (es)
TW (1) TWI339586B (es)
WO (1) WO2005041962A1 (es)
ZA (1) ZA200602056B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050220881A1 (en) * 2003-10-10 2005-10-06 Bvm Holding Co. Pharmaceutical composition
MXPA05013220A (es) * 2005-12-06 2007-06-05 Leopoldo De Jesus Espinosa Abdala Composiciones farmaceuticas que comprenden sustancias antidiabeticas combinadas para su uso en diabetes mellitus tipo 2.
JP5179363B2 (ja) * 2005-12-22 2013-04-10 武田薬品工業株式会社 固形製剤
BRPI0713371A2 (pt) 2006-06-27 2012-03-13 Daiichi Sankyo Company, Limited método para a produção de um produto medicamentoso contendo olmesartan medoxomil, e, produto medicamentoso contendo olmesartan medoxomil
DK2107905T3 (da) * 2007-02-01 2011-01-31 Takeda Pharmaceutical Fast sammensætning omfattende alogliptin og pioglitazon
IS8660A (is) * 2007-07-02 2009-01-03 Actavis Group Ptc Ehf. Gliklasíð lyfjasamsetning
WO2009120844A2 (en) * 2008-03-26 2009-10-01 Teva Pharmaceutical Industries Ltd. Pharmaceutical compositions comprising insulin sensitizer and insulin secretagogue
WO2010064147A2 (en) 2008-12-04 2010-06-10 Ikfe Gmbh Biomarkers for atherosclerosis
EP2376926A1 (en) 2008-12-11 2011-10-19 IKFE GmbH Biomarkers for insulin sensitizer drug response
EP2382467A1 (en) 2008-12-30 2011-11-02 IKFE GmbH Biomarkers for adipose tissue activity
EP2382475A2 (en) 2009-01-07 2011-11-02 IKFE GmbH Biomarkers for appetite regulation
CA2754950A1 (en) * 2009-03-20 2010-09-23 Smartcells, Inc. Terminally-functionalized conjugates and uses thereof
BR112013007469B1 (pt) * 2010-09-21 2020-03-31 Intekrin Therapeutics, Inc. Composições farmacêuticas antidiabéticas sólidas, seu uso e método de preparação, método para preparar um produto de granulação e composição precursora farmacêutica
EP2438911A1 (en) 2010-10-08 2012-04-11 LEK Pharmaceuticals d.d. Pharmaceuticals compositions comprising sulphonylurea-class insulin secretagogue and polyethylene glycol castor oil
WO2013034174A1 (en) * 2011-09-06 2013-03-14 ZENTIVA Saglik Ürünleri Sanayi ve Ticaret A.S. Solid preparations of pioglitazone and glimepiride
CN104288161A (zh) * 2014-09-19 2015-01-21 四川海思科制药有限公司 一种含吡格列酮格列美脲的药物组合物
KR20180006881A (ko) 2015-03-09 2018-01-19 인테크린 테라퓨틱스, 아이엔씨. 비알코올성 지방간 질환 및/또는 지방이영양증의 치료 방법
AU2018249822A1 (en) 2017-04-03 2019-10-31 Coherus Biosciences Inc. PPArgamma agonist for treatment of progressive supranuclear palsy
CN110548147B (zh) 2018-05-31 2022-01-14 华领医药技术（上海）有限公司 含有葡萄糖激酶激活剂和dpp-iv抑制剂的药物组合及其制备方法和用途

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5865213A (ja) * 1981-10-13 1983-04-18 Tokai Kapuseru Kk ｄｌ−２−（４，８，１２−トリメチルトリデシル）−２，５，７，８−テトラメチル−６−クロマニルニコチネ−ト軟カプセル剤
US4620974A (en) * 1983-07-07 1986-11-04 American Home Products Corporation Pharmaceutical composition containing a liquid lubricant
JP2764274B2 (ja) * 1988-03-28 1998-06-11 株式会社ミドリ十字 医薬組成物
DK0726761T3 (da) * 1993-11-03 2001-06-18 Isomed Inc Mikropartikulære farmaceutiske præparater på micel-form
HU212428B (en) * 1994-05-13 1996-06-28 Egyt Gyogyszervegyeszeti Gyar Process to prepare pharmaceutical compositions containing gemfibrozyl
TW438587B (en) * 1995-06-20 2001-06-07 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
EP0862562B1 (en) 1995-09-13 2001-07-04 Takeda Chemical Industries, Ltd. Benzoxazepine compounds, their production and use as lipid lowering agents
EP0811374A1 (en) * 1996-05-29 1997-12-10 Pfizer Inc. Combination dosage form comprising cetirizine and pseudoephedrine
GB9619757D0 (en) 1996-09-21 1996-11-06 Knoll Ag Chemical process
FR2758461A1 (fr) 1997-01-17 1998-07-24 Pharma Pass Composition pharmaceutique presentant une biodisponibilite elevee et son procede de preparation
US6011049A (en) 1997-02-19 2000-01-04 Warner-Lambert Company Combinations for diabetes
US5859037A (en) 1997-02-19 1999-01-12 Warner-Lambert Company Sulfonylurea-glitazone combinations for diabetes
US6291495B1 (en) 1997-02-24 2001-09-18 Robert B. Rieveley Method and composition for the treatment of diabetes
US6025372A (en) 1997-04-04 2000-02-15 Merck & Co., Inc. Somatostatin agonists
US6057338A (en) 1997-04-04 2000-05-02 Merck & Co., Inc. Somatostatin agonists
CA2294385C (en) 1997-06-18 2007-06-05 Smithkline Beecham P.L.C. Treatment of diabetes with thiazolidinedione and sulphonylurea
GB9715306D0 (en) 1997-07-18 1997-09-24 Smithkline Beecham Plc Novel method of treatment
GB9715295D0 (en) 1997-07-18 1997-09-24 Smithkline Beecham Plc Novel method of treatment
GB9715298D0 (en) 1997-07-18 1997-09-24 Smithkline Beecham Plc Novel method of treatment
CN1277550A (zh) * 1997-09-11 2000-12-20 尼科梅德丹麦有限公司 非甾体抗炎药物(NSAIDs)的改进释放的复合型组合物
AU1285499A (en) 1997-10-30 1999-05-24 Merck & Co., Inc. Somatostatin agonists
DE69939485D1 (de) 1998-11-12 2008-10-16 Smithkline Beecham Plc Arzneimittel zur gesteuerten freisetzung eines insulin sensibilisators und metformin
AR035016A1 (es) 1999-08-25 2004-04-14 Takeda Chemical Industries Ltd Composicion de azol promotor de produccion/secrecion de neurotrofina, compuesto prodroga del mismo, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima.
EP1227090A4 (en) 1999-10-07 2002-11-20 Tadeka Chemical Ind Ltd AMINE DERIVATIVES
US20030180352A1 (en) * 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6793934B1 (en) * 1999-12-08 2004-09-21 Shire Laboratories, Inc. Solid oral dosage form
US20010036479A1 (en) 2000-01-14 2001-11-01 Gillian Cave Glyburide composition
WO2001082925A1 (en) 2000-04-28 2001-11-08 Takeda Chemical Industries, Ltd. Melanin concentrating hormone antagonists
US6524621B2 (en) 2000-05-01 2003-02-25 Aeropharm Technology Inc. Core formulation
EP1283199A4 (en) 2000-05-16 2003-12-17 Takeda Chemical Industries Ltd MELANINE CONCENTRATING HORMONE ANTAGONISTS
JP4633329B2 (ja) 2001-01-12 2011-02-16 サン・ファーマ・アドバンスド・リサーチ・カンパニー・リミテッド スペーストドラッグデリバリーシステム
US20050245571A1 (en) 2001-10-19 2005-11-03 Hidenori Abe Amine derivative
US6682759B2 (en) * 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
CN100367960C (zh) 2002-07-11 2008-02-13 武田药品工业株式会社 包衣制剂的制备方法
UA80991C2 (en) 2002-10-07 2007-11-26 Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes
US20040147564A1 (en) 2003-01-29 2004-07-29 Rao Vinay U. Combinations of glimepiride and the thiazolidinedione for treatment of diabetes
MXPA05007883A (es) 2003-01-29 2005-09-21 Takeda Pharmaceutical Proceso para producir una preparacion recubierta.
FR2853831A1 (fr) * 2003-03-05 2004-10-22 Usv Ltd Forme posologique solide a usage oral de metformine et de glyburide et son procede de preparation

Also Published As

Publication number Publication date
AU2004285354A1 (en) 2005-05-12
PL1677792T3 (pl) 2016-05-31
KR20060061383A (ko) 2006-06-07
CY1117176T1 (el) 2017-04-05
ZA200602056B (en) 2007-05-30
KR100952090B1 (ko) 2010-04-13
TW200524641A (en) 2005-08-01
IL174201A (en) 2011-04-28
GEP20084570B (en) 2008-12-25
EP1677792B1 (en) 2015-11-18
ES2556244T3 (es) 2016-01-14
BRPI0414979A (pt) 2006-11-21
AU2004285354B2 (en) 2009-09-17
NO20062515L (no) 2006-07-31
DK1677792T3 (en) 2015-12-14
US20060223870A1 (en) 2006-10-05
RU2006118786A (ru) 2007-12-10
US7700128B2 (en) 2010-04-20
TWI339586B (en) 2011-04-01
IL174201A0 (en) 2006-08-01
HRP20151447T1 (hr) 2016-02-12
CN1874774A (zh) 2006-12-06
NO340294B1 (no) 2017-03-27
CA2540225C (en) 2012-03-06
MA28116A1 (fr) 2006-08-01
CN1874774B (zh) 2011-04-13
MXPA06004639A (es) 2006-06-27
WO2005041962A1 (en) 2005-05-12
PT1677792E (pt) 2016-02-09
JO3106B1 (ar) 2017-09-20
NZ546337A (en) 2009-03-31
SI1677792T1 (sl) 2016-02-29
RU2359661C2 (ru) 2009-06-27
EP1677792A1 (en) 2006-07-12
KR20100012105A (ko) 2010-02-05
AR046210A1 (es) 2005-11-30
CA2540225A1 (en) 2005-05-12
HUE028576T2 (en) 2016-12-28

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