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PE20040323A1 - Composiciones farmaceuticas de liberacion controlada, extendida que usan polimeros cargados - Google Patents

Composiciones farmaceuticas de liberacion controlada, extendida que usan polimeros cargados

Info

Publication number
PE20040323A1
PE20040323A1 PE2003000414A PE2003000414A PE20040323A1 PE 20040323 A1 PE20040323 A1 PE 20040323A1 PE 2003000414 A PE2003000414 A PE 2003000414A PE 2003000414 A PE2003000414 A PE 2003000414A PE 20040323 A1 PE20040323 A1 PE 20040323A1
Authority
PE
Peru
Prior art keywords
extended
pharmaceutical compositions
controlled release
release pharmaceutical
charged polymers
Prior art date
Application number
PE2003000414A
Other languages
English (en)
Inventor
William J Bologna
Howard L Levine
Original Assignee
Columbia Lab Bermuda Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/278,912 external-priority patent/US20030114394A1/en
Application filed by Columbia Lab Bermuda Ltd filed Critical Columbia Lab Bermuda Ltd
Publication of PE20040323A1 publication Critical patent/PE20040323A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

QUE COMPRENDE: 1)UN AGENTE DE TRATAMIENTO IONICO, TAL COMO AMITRIPTILINA, AMANTADINA, AMIODARONA, MECLIZINA, DIFENHIDRAMINA, HIDROXIZINA O ATROPINA, ENTRE OTROS; 2)UN POLIMERO IONICO, SUFICIENTEMENTE IONIZADO, PARA PROPORCIONAR LA UNION CON (1), PARA PERMITIR QUE LA COMPOSICION LIBERE DICHO AGENTE, EN FORMA CONTROLADA, DURANTE UN PERIODO DE TIEMPO EXTENDIDO, DE POR LO MENOS 6 HORAS, EL CUAL PUEDE SER: UN POLIMERO DE ACIDO POLICARBOXILICO ENTRECRUZADO BIOADHESIVO, QUE PUEDE HINCHARSE EN AGUA, PERO ES INSOLUBLE EN ELLA; Y, 3)UN AGENTE BIOADHESIVO. DONDE, DICHA COMPOSICION NO REQUIERE UN SISTEMA DE EMULSION PARA ADMINISTRAR EL AGENTE DE TRATAMIENTO
PE2003000414A 2002-10-24 2003-04-25 Composiciones farmaceuticas de liberacion controlada, extendida que usan polimeros cargados PE20040323A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/278,912 US20030114394A1 (en) 2001-10-29 2002-10-24 Vaginally administered anti-dysrhythmic agents for treating pelvic pain
US43850103P 2003-01-08 2003-01-08

Publications (1)

Publication Number Publication Date
PE20040323A1 true PE20040323A1 (es) 2004-06-10

Family

ID=32179474

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2008001302A PE20081613A1 (es) 2002-10-24 2003-04-25 Composiciones farmaceuticas de liberacion controlada, extendida que usan polimeros cargados
PE2003000414A PE20040323A1 (es) 2002-10-24 2003-04-25 Composiciones farmaceuticas de liberacion controlada, extendida que usan polimeros cargados

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PE2008001302A PE20081613A1 (es) 2002-10-24 2003-04-25 Composiciones farmaceuticas de liberacion controlada, extendida que usan polimeros cargados

Country Status (23)

Country Link
EP (1) EP1556015B1 (es)
JP (1) JP5204374B2 (es)
KR (1) KR20050083802A (es)
CN (2) CN101327326A (es)
AR (1) AR039464A1 (es)
AU (1) AU2003233066B2 (es)
BR (1) BR0315576A (es)
CA (1) CA2503383C (es)
CO (1) CO5700711A2 (es)
ES (1) ES2618300T3 (es)
HR (1) HRP20050448A2 (es)
MA (1) MA27493A1 (es)
ME (2) MEP34108A (es)
MX (1) MXPA05004330A (es)
NO (1) NO20052480L (es)
NZ (1) NZ539512A (es)
PE (2) PE20081613A1 (es)
PL (1) PL376537A1 (es)
RS (1) RS20050321A (es)
RU (2) RU2366410C2 (es)
TW (1) TW200406223A (es)
WO (1) WO2004037229A1 (es)
ZA (1) ZA200503133B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1888038A2 (en) * 2005-05-10 2008-02-20 Novartis AG Modified release famciclovir pharmaceutical compositions
WO2017130208A1 (en) * 2016-01-29 2017-08-03 Faheem Hyder Pottoo Triple drug combination for treatment of status epilepticus and/or partial seizures and/or partial seizures with associated neurological disorders
CN119074731A (zh) * 2024-09-20 2024-12-06 湖南师范大学 盐酸达克罗宁在预防雌性小鼠下丘脑-垂体-卵巢轴损伤中的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0830004B2 (ja) * 1983-11-14 1996-03-27 コロンビア ラボラトリーズ インコーポレイテッド 生物接着性組成物およびそれにより治療する方法
DK0431719T3 (da) * 1989-10-31 1995-02-27 Columbia Lab Inc Vaginalt vævsbefugtende præparat
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of erythromycin derivatives
US5578315A (en) * 1993-12-01 1996-11-26 Rutgers, The State University Of New Jersey Mucosal adhesive device for long-acting delivery of pharmaceutical combinations in oral cavity
IL128774A (en) * 1994-03-07 2001-05-20 Dow Chemical Co Composition comprising a dendritic poymer in complex with at least one unit of biological response modifier and a process for the preparation thereof
US5667492A (en) * 1994-10-07 1997-09-16 Columbia Laboratories, Inc. Use and composition of an anti-sexually transmitted diseases formulation
US6197327B1 (en) * 1997-06-11 2001-03-06 Umd, Inc. Device and method for treatment of dysmenorrhea
US6248358B1 (en) * 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
US6624200B2 (en) * 1998-08-25 2003-09-23 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
DE69819748T2 (de) * 1997-09-12 2004-09-30 Columbia Laboratories (Bermuda) Ltd. Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen
UA74168C2 (uk) * 1999-10-05 2005-11-15 Коламбіа Леборетеріс (Бермуда) Лімітед Лікування ендометріозу або безпліддя, або покращення плідності та застосування бета-адренергічного агоніста для виробництва лікарського засобу

Also Published As

Publication number Publication date
HRP20050448A2 (en) 2005-12-31
CN101327326A (zh) 2008-12-24
CA2503383C (en) 2013-03-12
PE20081613A1 (es) 2008-11-15
CO5700711A2 (es) 2006-11-30
ZA200503133B (en) 2006-12-27
BR0315576A (pt) 2005-08-30
JP5204374B2 (ja) 2013-06-05
TW200406223A (en) 2004-05-01
AU2003233066A1 (en) 2004-05-13
RS20050321A (sr) 2007-08-03
MA27493A1 (fr) 2005-08-01
RU2366410C2 (ru) 2009-09-10
CA2503383A1 (en) 2004-05-06
MXPA05004330A (es) 2005-08-02
ME00233B (me) 2011-05-10
MEP34108A (hr) 2011-02-10
EP1556015A1 (en) 2005-07-27
NO20052480L (no) 2005-07-25
CN1703205A (zh) 2005-11-30
RU2005115574A (ru) 2005-10-27
AR039464A1 (es) 2005-02-23
PL376537A1 (pl) 2006-01-09
CN1703205B (zh) 2010-12-01
WO2004037229A1 (en) 2004-05-06
KR20050083802A (ko) 2005-08-26
NO20052480D0 (no) 2005-05-23
RU2009112072A (ru) 2010-10-10
EP1556015B1 (en) 2017-02-22
JP2006506453A (ja) 2006-02-23
AU2003233066B2 (en) 2009-11-19
NZ539512A (en) 2009-03-31
ES2618300T3 (es) 2017-06-21

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Legal Events

Date Code Title Description
FC Refusal
FG Grant, registration
FD Application declared void or lapsed