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PE20040623A1 - COMBINATION OF NMDA ANTAGONIST WITH ACETYLCHOLINE ESTERASE INHIBITORS - Google Patents

COMBINATION OF NMDA ANTAGONIST WITH ACETYLCHOLINE ESTERASE INHIBITORS

Info

Publication number
PE20040623A1
PE20040623A1 PE2003000527A PE2003000527A PE20040623A1 PE 20040623 A1 PE20040623 A1 PE 20040623A1 PE 2003000527 A PE2003000527 A PE 2003000527A PE 2003000527 A PE2003000527 A PE 2003000527A PE 20040623 A1 PE20040623 A1 PE 20040623A1
Authority
PE
Peru
Prior art keywords
combination
acetylcholine esterase
nmda antagonist
esterase inhibitors
inhibitors
Prior art date
Application number
PE2003000527A
Other languages
Spanish (es)
Inventor
Lars Lykke Thomsen
Anders Gersel Pedersen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=28051666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20040623(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of PE20040623A1 publication Critical patent/PE20040623A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/473Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: (A) UNO O MAS INHIBIDORES DE ACELTILCOLINESTERASA O UNA SAL DEL MISMO TAL COMO TACRINA, DONEPEZIL, RIVASTIGMINA, ENTRE OTROS; (B) UNO O MAS ANTAGONISTAS DE NMDA COMO MEMANTINA. DONDE (A) Y (B) PUEDEN HALLARSE EN EL MISMO VEHICULO O NO; Y PUEDEN SER ADMINISTRADOS SIMULTANEAMENTE O CONCOMITANTEMENTE. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DEL ALZHEIMER, DEL DETERIORO COGNITIVO LEVE O LA DEMENCIAIT REFERS TO A PHARMACEUTICAL COMPOSITION THAT INCLUDES: (A) ONE OR MORE ACELTILCOLINESTERASE INHIBITORS OR A SALT OF THE SAME SUCH AS TACRINE, DONEPEZIL, RIVASTIGMINE, AMONG OTHERS; (B) ONE OR MORE NMDA ANTAGONISTS AS MEMANTINE. WHERE (A) AND (B) CAN BE FOUND IN THE SAME VEHICLE OR NOT; AND THEY CAN BE ADMINISTERED SIMULTANEOUSLY OR CONCOMITANTLY. SUCH COMPOSITION IS USEFUL IN THE TREATMENT OF ALZHEIMER, MILD COGNITIVE IMPAIRMENT OR DEMENTIA

PE2003000527A 2002-05-31 2003-05-29 COMBINATION OF NMDA ANTAGONIST WITH ACETYLCHOLINE ESTERASE INHIBITORS PE20040623A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200200844 2002-05-31

Publications (1)

Publication Number Publication Date
PE20040623A1 true PE20040623A1 (en) 2004-09-11

Family

ID=28051666

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2003000527A PE20040623A1 (en) 2002-05-31 2003-05-29 COMBINATION OF NMDA ANTAGONIST WITH ACETYLCHOLINE ESTERASE INHIBITORS

Country Status (9)

Country Link
KR (1) KR101016927B1 (en)
CN (1) CN1655793A (en)
AR (1) AR040121A1 (en)
CA (1) CA2426492C (en)
EA (1) EA007632B1 (en)
IS (1) IS7558A (en)
PE (1) PE20040623A1 (en)
UA (1) UA82480C2 (en)
ZA (1) ZA200409147B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA107653U (en) 2012-10-01 2016-06-24 Общєство С Огранічєнной Отвєтствєнностью "Валєнта-Інтєллєкт" COMPOSITION OF MEDICINAL PRODUCTS FOR TREATMENT AND PREVENTION OF BEHAVIORAL, MENTAL, AND COGNITIVE DISORDERS
CN118239847A (en) * 2014-05-29 2024-06-25 广州喜鹊医药有限公司 Preparation method of amantadine nitrate compound with neuroprotection effect
WO2018062941A1 (en) * 2016-09-30 2018-04-05 주식회사 바이오파마티스 Pharmaceutical composition for preventing or treating dementia and cognitive dysfunction, containing donepezil or pharmaceutically acceptable salt thereof and memantine or pharmaceutically acceptable salt thereof, and preparation method therefor
KR20210072569A (en) 2019-12-09 2021-06-17 주식회사 종근당 Complex formulation comprising donepezil and memantine

Also Published As

Publication number Publication date
EA007632B1 (en) 2006-12-29
EA200401617A1 (en) 2005-06-30
AR040121A1 (en) 2005-03-16
KR20050024296A (en) 2005-03-10
IS7558A (en) 2004-11-26
CA2426492A1 (en) 2003-09-16
CA2426492C (en) 2006-10-03
ZA200409147B (en) 2006-06-28
KR101016927B1 (en) 2011-02-28
UA82480C2 (en) 2008-04-25
CN1655793A (en) 2005-08-17

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