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PE20030207A1 - ACETYLSALICILIC ACID SOLUTIONS - Google Patents

ACETYLSALICILIC ACID SOLUTIONS

Info

Publication number
PE20030207A1
PE20030207A1 PE2001000218A PE2001000218A PE20030207A1 PE 20030207 A1 PE20030207 A1 PE 20030207A1 PE 2001000218 A PE2001000218 A PE 2001000218A PE 2001000218 A PE2001000218 A PE 2001000218A PE 20030207 A1 PE20030207 A1 PE 20030207A1
Authority
PE
Peru
Prior art keywords
volume
acid solutions
solvent
solution
water
Prior art date
Application number
PE2001000218A
Other languages
Spanish (es)
Inventor
Wolfgang Wiehl
Martina Wirtz
Dietmar Bahn
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PE20030207A1 publication Critical patent/PE20030207A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE REFIERE A SOLUCIONES DE 3g A 30 g DE ACIDO ACETILSALICILO, CONTENIENDO EL DISOLVENTE DE 1 A 20% EN VOLUMEN DE AGUA Y 80 A 99% EN VOLUMEN DE DISOLVENTE ORGANICO EN 100 ml DE SOLUCION. EL DISOLVENTE ORGANICO SE SELECCIONA DE ETANOL, PROPANO, ISOPROPANOL, BUTANO, ISOBUTANOL, ENTRE OTROS. EL DISOLVENTE COENTINE DE 30% A 80% DE VOLUMEN DE ETER , DE 17% A 67% DE VOLUMEN DE ALCOHOL O ACETONA Y DE 3% A 10% EN VOLUMEN DE AGUA. LA SOLUCION ES UTIL PARA EL TRATAMIENTO TOPICO DEL DOLOR COMO HERPES ZOSTER, PRURITO, NEURODERMITISREFERS TO SOLUTIONS OF 3g TO 30 g OF ACETYLSALICIL ACID, THE SOLVENT CONTAINING 1 TO 20% BY VOLUME OF WATER AND 80 TO 99% BY VOLUME OF ORGANIC SOLVENT IN 100 ml OF SOLUTION. THE ORGANIC SOLVENT IS SELECTED FROM ETHANOL, PROPANE, ISOPROPANOL, BUTANE, ISOBUTANOL, AMONG OTHERS. THE SOLVENT COENTINE FROM 30% TO 80% BY VOLUME OF ETHER, FROM 17% TO 67% BY VOLUME OF ALCOHOL OR ACETONE AND FROM 3% TO 10% BY VOLUME OF WATER. THE SOLUTION IS USEFUL FOR THE TOPICAL TREATMENT OF PAIN SUCH AS HERPES ZOSTER, PRURITO, NEURODERMITIS

PE2001000218A 2000-03-07 2001-03-06 ACETYLSALICILIC ACID SOLUTIONS PE20030207A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10011032A DE10011032A1 (en) 2000-03-07 2000-03-07 Stable solutions of acetylsalicylic acid in mixture of organic solvent and water, useful for topical treatment of pain, especially pain associated with herpes zoster

Publications (1)

Publication Number Publication Date
PE20030207A1 true PE20030207A1 (en) 2003-04-16

Family

ID=7633806

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2001000218A PE20030207A1 (en) 2000-03-07 2001-03-06 ACETYLSALICILIC ACID SOLUTIONS

Country Status (9)

Country Link
EP (1) EP1263441A2 (en)
AR (1) AR028237A1 (en)
AU (1) AU2001272099A1 (en)
DE (1) DE10011032A1 (en)
GT (1) GT200100035A (en)
HN (1) HN2001000039A (en)
PE (1) PE20030207A1 (en)
SV (1) SV2002000339A (en)
WO (1) WO2001066115A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070196460A1 (en) * 2004-02-16 2007-08-23 Yukiko Inamoto External preparation for treating skin or mucosal injury caused by viral infection
WO2007125492A2 (en) * 2006-05-02 2007-11-08 Pfeinsmith S.A. (Pty) Ltd Acidic composition
JP7335232B2 (en) * 2017-05-30 2023-08-29 ローシャン ファーマシューティカルズ，インコーポレーテッド Intravial Deposits of Stable, Sterile and Crystalline O-Acetylsalicylic Acid (Aspirin)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4219548A (en) * 1978-09-01 1980-08-26 The Procter & Gamble Company Topical anti-inflammatory composition
IL68965A (en) * 1983-06-13 1987-02-27 Rafa Labor Ltd Topical pharmaceutical preparation comprising acetylsalicylic acid for the treatment of dermatological disorders
WO1995019759A1 (en) * 1994-01-24 1995-07-27 The Procter & Gamble Company Process for solubilizing difficultly soluble pharmaceutical actives
US5484606A (en) * 1994-01-24 1996-01-16 The Procter & Gamble Company Process for reducing the precipitation of difficulty soluble pharmaceutical actives

Also Published As

Publication number Publication date
EP1263441A2 (en) 2002-12-11
AR028237A1 (en) 2003-04-30
AU2001272099A1 (en) 2001-09-17
GT200100035A (en) 2001-12-18
HN2001000039A (en) 2001-07-09
WO2001066115A3 (en) 2002-02-14
WO2001066115A2 (en) 2001-09-13
SV2002000339A (en) 2002-06-07
DE10011032A1 (en) 2001-09-13

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal