PE20010303A1 - Nueva preparacion y forma de presentacion que contiene un agente activo labil en medio acido que consiste en un inhibidor de la bomba de protones labil en medio acido - Google Patents
Nueva preparacion y forma de presentacion que contiene un agente activo labil en medio acido que consiste en un inhibidor de la bomba de protones labil en medio acidoInfo
- Publication number
- PE20010303A1 PE20010303A1 PE2000000565A PE0005652000A PE20010303A1 PE 20010303 A1 PE20010303 A1 PE 20010303A1 PE 2000000565 A PE2000000565 A PE 2000000565A PE 0005652000 A PE0005652000 A PE 0005652000A PE 20010303 A1 PE20010303 A1 PE 20010303A1
- Authority
- PE
- Peru
- Prior art keywords
- acid medium
- labil
- inhibitor
- presentation
- proton pump
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 3
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- -1 FATTY ACID ESTER Chemical class 0.000 abstract 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 abstract 1
- MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical compound CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 abstract 1
- IQPSEEYGBUAQFF-UHFFFAOYSA-N Pantoprazole Chemical compound COC1=CC=NC(CS(=O)C=2NC3=CC=C(OC(F)F)C=C3N=2)=C1OC IQPSEEYGBUAQFF-UHFFFAOYSA-N 0.000 abstract 1
- 102000006270 Proton Pumps Human genes 0.000 abstract 1
- 108010083204 Proton Pumps Proteins 0.000 abstract 1
- CZSWPTDFGFHVTR-UHFFFAOYSA-N acetic acid;1-ethenylpyrrolidin-2-one Chemical compound CC(O)=O.C=CN1CCCC1=O CZSWPTDFGFHVTR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 229920003086 cellulose ether Polymers 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 229960003194 meglumine Drugs 0.000 abstract 1
- 239000011806 microball Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960005019 pantoprazole Drugs 0.000 abstract 1
- 239000012188 paraffin wax Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 229940069328 povidone Drugs 0.000 abstract 1
- 229910000029 sodium carbonate Inorganic materials 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
- ORGHESHFQPYLAO-UHFFFAOYSA-N vinyl radical Chemical class C=[CH] ORGHESHFQPYLAO-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE A UNA FORMA DE PRESENTACION PARA AGENTES ACTIVOS LABILES EN MEDIO ACIDO QUE COMPRENDE ADYUVANTES FARMACEUTICOS; UNIDADES INDIVIDUALES MULTIPLES DE AGENTE ACTIVO TAL COMO MICROBOLAS CONTENIDO UN INHIBIDOR DE LAS BOMBAS DE PROTONES LABIL TAL COMO PANTOPRAZOL, CARACTERIZADO PORQUE EL AGENTE ACTIVO SE ENCUENTRA EN UNA MATRIZ CONSTITUIDA POR UNA MEZCLA QUE CONTIENE AL MENOS i)UN ALCOHOL GRASO; ii)UN TRIGLICERIDO; iii)UN ESTER DE ACIDO GRASO Y AL MENOS UNA PARAFINA SOLIDA; TAMBIEN PUEDE COMPRENDER LA FORMA DE PRESENTACION ADYUVANTES ADICIONALES TAL COMO POLIMEROS (POVIDONA, COPOLIMERO VINILPIRROLIDONA ACETATO DE VINILO, POLIACETATO DE VINILO, ETER DE CELULOSA, ENTRE OTROS), ESTEROLES (ERGOSTERINA, ESTIGMASTEROL, SITOSTEROL, ENTRE OTROS), COMPUESTOS BASICOS (CARBONATO DE AMONIO, CARBONATO DE SODIO, MEGLUMINA, TRIETILAMINA, ENTRE OTROS). TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19925710A DE19925710C2 (de) | 1999-06-07 | 1999-06-07 | Neue Zubereitung und Darreichungsform enthaltend einen säurelabilen Protonenpumpenhemmer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20010303A1 true PE20010303A1 (es) | 2001-03-09 |
Family
ID=7910295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2000000565A PE20010303A1 (es) | 1999-06-07 | 2000-06-07 | Nueva preparacion y forma de presentacion que contiene un agente activo labil en medio acido que consiste en un inhibidor de la bomba de protones labil en medio acido |
Country Status (6)
| Country | Link |
|---|---|
| AR (1) | AR024310A1 (es) |
| CO (1) | CO5160296A1 (es) |
| DE (1) | DE19925710C2 (es) |
| MY (1) | MY138975A (es) |
| PE (1) | PE20010303A1 (es) |
| TW (1) | TWI255720B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA80393C2 (uk) | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
| DE10061135C1 (de) * | 2000-12-07 | 2002-11-07 | Byk Gulden Lomberg Chem Fab | Pharmazeutische Zubereitung in Form einer Paste enthaltend einen säurelabilen Wirkstoff |
| BR0115986A (pt) * | 2000-12-07 | 2003-12-23 | Altana Pharma Ag | Comprimido de desintegração rápida contendo um ingrediente ativo instável aos ácidos |
| JP5009482B2 (ja) | 2000-12-07 | 2012-08-22 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 酸に不安定な活性成分を含有する懸濁液の形の製薬製剤 |
| CN100536844C (zh) * | 2000-12-07 | 2009-09-09 | 尼科梅德有限责任公司 | 包含酸不稳定活性成分的糊剂形式的药物制剂 |
| DE10061137B4 (de) * | 2000-12-07 | 2016-10-06 | Takeda Gmbh | Neue pharmazeutische Zubereitung |
| DE10061138C1 (de) * | 2000-12-07 | 2002-08-14 | Byk Gulden Lomberg Chem Fab | Pharmazeutische Zubereitung in Form eines Saftes enthaltend einen säurelabilen Wirkstoff |
| DE10061136C1 (de) * | 2000-12-07 | 2002-10-24 | Byk Gulden Lomberg Chem Fab | Schnell zerfallende Tablette enthaltend einen säurelabilen Protonenpumpenhemmer |
| SE0101379D0 (sv) | 2001-04-18 | 2001-04-18 | Diabact Ab | Komposition som hämmar utsöndring av magsyra |
| CN1596104A (zh) | 2001-09-28 | 2005-03-16 | 麦克内尔-Ppc股份有限公司 | 改进的释放剂型 |
| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| CA2490142A1 (en) * | 2002-07-03 | 2004-01-15 | Abbott Laboratories | Liquid dosage forms of proton pump inhibitors |
| DE10244129B4 (de) * | 2002-09-23 | 2006-04-20 | Iongate Biosciences Gmbh | H+-K+-ATPase-Assay |
| SE0203065D0 (sv) | 2002-10-16 | 2002-10-16 | Diabact Ab | Gastric acid secretion inhibiting composition |
| DK1606261T3 (da) | 2003-03-10 | 2010-01-18 | Nycomed Gmbh | Hidtil ukendt fremgangsmåde til fremstilling af roflumilast |
| TW200503783A (en) * | 2003-04-11 | 2005-02-01 | Altana Pharma Ag | Oral pharmaceutical preparation for proton pump antagonists |
| EP2258350B1 (en) | 2005-03-16 | 2014-12-24 | Takeda GmbH | Taste masked dosage form containing roflumilast |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2725924C3 (de) * | 1977-06-08 | 1980-11-06 | Hobeg Hochtemperaturreaktor-Brennelement Gmbh, 6450 Hanau | Verfahren zur Herstellung kugelförmiger Teilchen aus niedrigschmelzenden organischen Substanzen |
| DE3524572A1 (de) * | 1985-07-10 | 1987-01-15 | Thomae Gmbh Dr K | Feste arzneimittelformen zur peroralen anwendung enthaltend 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin und verfahren zu ihrer herstellung |
| JP2681373B2 (ja) * | 1988-07-18 | 1997-11-26 | 塩野義製薬株式会社 | 徐放性製剤の製造法 |
-
1999
- 1999-06-07 DE DE19925710A patent/DE19925710C2/de not_active Expired - Fee Related
-
2000
- 2000-05-30 MY MYPI20002403A patent/MY138975A/en unknown
- 2000-05-30 CO CO00040091A patent/CO5160296A1/es unknown
- 2000-06-07 TW TW089111052A patent/TWI255720B/zh not_active IP Right Cessation
- 2000-06-07 AR ARP000102825A patent/AR024310A1/es unknown
- 2000-06-07 PE PE2000000565A patent/PE20010303A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CO5160296A1 (es) | 2002-05-30 |
| DE19925710C2 (de) | 2002-10-10 |
| MY138975A (en) | 2009-08-28 |
| AR024310A1 (es) | 2002-09-25 |
| DE19925710A1 (de) | 2000-12-14 |
| TWI255720B (en) | 2006-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |