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PE20000381A1 - NEW FORMULATIONS OF PAROXETINE - Google Patents

NEW FORMULATIONS OF PAROXETINE

Info

Publication number
PE20000381A1
PE20000381A1 PE1998001126A PE00112698A PE20000381A1 PE 20000381 A1 PE20000381 A1 PE 20000381A1 PE 1998001126 A PE1998001126 A PE 1998001126A PE 00112698 A PE00112698 A PE 00112698A PE 20000381 A1 PE20000381 A1 PE 20000381A1
Authority
PE
Peru
Prior art keywords
paroxetine
presented
solid
semi
refers
Prior art date
Application number
PE1998001126A
Other languages
Spanish (es)
Inventor
Ghazawi Ahmad
Leonard Graham Stanley
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of PE20000381A1 publication Critical patent/PE20000381A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SE REFIERE A UNA COMPOSICION QUE SE PRESENTA EN FORMA DE CAPSULA QUE CONTIENE 1)PAROXETINA O LA BASE LIBRE O EL HEMIHIDRATO O EL ANHIDRATO DEL HIDROCLORURO O HIDROCLORURO AMORFO O ANHIDRATO CRISTALINO; 2)VEHICULO QUE SE PUEDEN PRESENTAR COMO a)LIQUIDO FLUIBLE O LIQUIDO VISCOSO O SEMISOLIDO O GEL; b)SOLIDO O SEMISOLIDO COMO CERAS Y GRASAS NATURALES O SINTETICAS; c)POLIMEROS QUE FORMAN PELICULAS O TERMOPLASTICOS; 3)EXCIPIENTES HIDROFOBOS O ANHIDROS. LA COMPOSICION TAMBIEN SE PUEDE PRESENTAR EN FORMA DE TABLETAS, PERLAS, ESFERULAS, GRANULOS, PASTILLAS O GELES; QUE PUEDE ESTAR REVESTIDA PARA RETARDAR O CONTROLAR LA LIBERACION DE PAROXETINA O PARA ENMASCARAR EL SABOR O PARA FACILITAR SU ADMINISTRACION. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION. LA PAROXETINA ES UTIL PARA EL TRATAMIENTO Y PROFILAXIS DE DEPRESION, TRASTORNO COMPULSIVO OBSESIVO Y PANICOIT REFERS TO A COMPOSITION PRESENTED IN THE FORM OF A CAPSULE CONTAINING 1) PAROXETINE OR THE FREE BASE OR HYDROCHLORIDE HEMIHYDRATE OR AMORPHO HYDROCHLORIDE OR CRYSTALLINE ANHYDRATE; 2) VEHICLE THAT MAY BE PRESENTED AS a) FLUIBLE LIQUID OR VISCOUS OR SEMI-SOLID LIQUID OR GEL; b) SOLID OR SEMI-SOLID AS NATURAL OR SYNTHETIC WAXES AND FATS; c) POLYMERS THAT FORM FILMS OR THERMOPLASTICS; 3) HYDROPHOBIC OR ANHYDROUS EXCIPIENTS. THE COMPOSITION CAN ALSO BE PRESENTED IN THE FORM OF TABLETS, PEARLS, SPHERULES, GRANULES, PILLS OR GELS; WHICH MAY BE COATED TO DELAY OR CONTROL THE RELEASE OF PAROXETINE OR TO MASK THE FLAVOR OR TO FACILITATE ITS ADMINISTRATION. IT ALSO REFERS TO A PROCEDURE FOR PREPARATION. PAROXETINE IS USEFUL FOR THE TREATMENT AND PROPHYLAXIS OF DEPRESSION, OBSESSIVE COMPULSIVE DISORDER AND PANIC

PE1998001126A 1997-11-21 1998-11-18 NEW FORMULATIONS OF PAROXETINE PE20000381A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9724544.3A GB9724544D0 (en) 1997-11-21 1997-11-21 Novel Formulation

Publications (1)

Publication Number Publication Date
PE20000381A1 true PE20000381A1 (en) 2000-05-07

Family

ID=10822374

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1998001126A PE20000381A1 (en) 1997-11-21 1998-11-18 NEW FORMULATIONS OF PAROXETINE

Country Status (24)

Country Link
EP (1) EP1033986A1 (en)
JP (1) JP2001523718A (en)
KR (1) KR20010032320A (en)
CN (1) CN1279608A (en)
AP (1) AP2000001821A0 (en)
AR (1) AR015485A1 (en)
AU (1) AU1168099A (en)
BG (1) BG104527A (en)
BR (1) BR9814220A (en)
CO (1) CO4970832A1 (en)
DZ (1) DZ2658A1 (en)
EA (1) EA200000552A1 (en)
GB (1) GB9724544D0 (en)
HU (1) HUP0100580A3 (en)
IL (1) IL136106A0 (en)
MA (1) MA24704A1 (en)
NO (1) NO20002590L (en)
OA (1) OA11385A (en)
PE (1) PE20000381A1 (en)
PL (1) PL340555A1 (en)
SK (1) SK7342000A3 (en)
TR (1) TR200001423T2 (en)
WO (1) WO1999026625A1 (en)
ZA (1) ZA9810637B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9810180D0 (en) * 1998-05-13 1998-07-08 Smithkline Beecham Plc Novel formulation
ATE311883T1 (en) 1999-03-12 2005-12-15 Aesica Pharmaceuticals Ltd STABLE PHARMACEUTICAL USE FORM FOR PAROXETINE ANHYDRATE
CA2341984A1 (en) 1999-07-01 2001-01-11 Paolo Mascagni Complexes of paroxetine, with cyclodextrines or cyclodextrin derivatives
DE19930454A1 (en) * 1999-07-02 2001-01-04 Knoll Ag Solid paroxetine-containing preparations
US6720003B2 (en) 2001-02-16 2004-04-13 Andrx Corporation Serotonin reuptake inhibitor formulations
US7011846B2 (en) * 2001-12-21 2006-03-14 Shire Laboratories, Inc. Oral capsule formulation with increased physical stability
SE0200475D0 (en) * 2002-02-15 2002-02-15 Ltp Lipid Technologies Provide Oral pharmaceutical preparation
WO2006119779A2 (en) * 2005-05-10 2006-11-16 Lifecycle Pharma A/S A pharmaceutical composition comprising an aldosterone antagonist in form of solid solution
US20120322752A1 (en) * 2009-12-08 2012-12-20 Sung Kyun Lee SOLID DISPERSIONS CONTAINING 20-O-beta-D-GLUCOPYRANOSYL-20(S)-PROTOPANAXADIOL
GB201020032D0 (en) * 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
CN103961333B (en) * 2014-05-07 2020-02-21 浙江华海药业股份有限公司 Paroxetine mesylate capsule and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9707585A (en) * 1995-04-03 1997-12-31 Abbott Lab Homogeneous mixtures of low temperature-melting drugs and additives for controlled release.
SK95099A3 (en) * 1997-01-15 2000-01-18 Smithkline Beecham Plc Process for the preparation of free-flowing form of paroxetine hydrochloride, pharmaceutical composition containing same and use thereof

Also Published As

Publication number Publication date
GB9724544D0 (en) 1998-01-21
TR200001423T2 (en) 2000-10-23
HUP0100580A3 (en) 2002-05-28
MA24704A1 (en) 1999-07-01
PL340555A1 (en) 2001-02-12
SK7342000A3 (en) 2000-12-11
BR9814220A (en) 2001-12-26
KR20010032320A (en) 2001-04-16
AU1168099A (en) 1999-06-15
CN1279608A (en) 2001-01-10
IL136106A0 (en) 2001-05-20
AR015485A1 (en) 2001-05-02
DZ2658A1 (en) 2003-03-22
AP2000001821A0 (en) 2000-06-30
BG104527A (en) 2001-04-30
OA11385A (en) 2004-01-27
WO1999026625A1 (en) 1999-06-03
NO20002590L (en) 2000-07-19
HUP0100580A2 (en) 2002-04-29
ZA9810637B (en) 2000-05-22
JP2001523718A (en) 2001-11-27
CO4970832A1 (en) 2000-11-07
NO20002590D0 (en) 2000-05-19
EP1033986A1 (en) 2000-09-13
EA200000552A1 (en) 2000-10-30

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