PE20000468A1 - Proceso para la preparacion de una composicion farmaceutica oral que comprende un antibiotico - Google Patents
Proceso para la preparacion de una composicion farmaceutica oral que comprende un antibioticoInfo
- Publication number
- PE20000468A1 PE20000468A1 PE1999000382A PE00038299A PE20000468A1 PE 20000468 A1 PE20000468 A1 PE 20000468A1 PE 1999000382 A PE1999000382 A PE 1999000382A PE 00038299 A PE00038299 A PE 00038299A PE 20000468 A1 PE20000468 A1 PE 20000468A1
- Authority
- PE
- Peru
- Prior art keywords
- antibiotic
- preparation
- pharmaceutical composition
- oral pharmaceutical
- refers
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 3
- 239000003242 anti bacterial agent Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008203 oral pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- QQONPFPTGQHPMA-UHFFFAOYSA-N Propene Chemical compound CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 abstract 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- 108010010803 Gelatin Chemical class 0.000 abstract 1
- -1 METHYLACRYLIC ACID METHYL Chemical class 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000013019 agitation Methods 0.000 abstract 1
- 229920006318 anionic polymer Polymers 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 235000019636 bitter flavor Nutrition 0.000 abstract 1
- 229920003118 cationic copolymer Polymers 0.000 abstract 1
- 239000001913 cellulose Chemical class 0.000 abstract 1
- 229920002678 cellulose Chemical class 0.000 abstract 1
- 229940075614 colloidal silicon dioxide Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960000913 crospovidone Drugs 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229920000159 gelatin Chemical class 0.000 abstract 1
- 239000008273 gelatin Chemical class 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 238000000227 grinding Methods 0.000 abstract 1
- 239000003906 humectant Substances 0.000 abstract 1
- 238000002156 mixing Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 229920000642 polymer Chemical class 0.000 abstract 1
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 abstract 1
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
- 150000008163 sugars Chemical class 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000002562 thickening agent Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A UN PROCESO PARA LA PREPARACION DE UNA COMPOSICION FARMACEUTICA ORAL DE UN ANTIBIOTICO (ROXITROMICINA) EN FORMA DE POLVO QUE PERMITA DISIMULAR EL SABOR AMARGO DEL PRINCIPIO ACTIVO; QUE COMPRENDE LAS ETAPAS DE : a) MEZCLADO, POR AGITACION DEL ANTIBIOTICO CON UNO O MAS AGLUTINANTES, ESPESANTES, HUMECTANTES SIENDO DE PREFERENCIA GOMAS HIDROFILICAS, AZUCARES, POLIMEROS, GELATINA, DERIVADOS DE CELULOSA; ADEMAS SE PUEDE ADICIONAR DIOXIDO DE SILICIO COLOIDAL Y CROSPOVIDONA; JUNTAMENTE CON POR LO MENOS UN COMPUESTO FORMADOR DE PELICULA SIENDO DE PREFERENCIA ETILCELULOSA, COPOLIMEROS CATIONICOS DE METACRILATO DE DIMETILAMINOACETIL Y ESTERES NEUTROS DE ACIDO METACRILICO O POLIMEROS ANIONICOS DE ACIDO METACRILICO, ESTER METILICO DE ACIDO METACRILICO; b) SECADO Y MOLIDO DE LA MASA RESULTANTE; c) FORMACION DE GRANULOS DE TAMANO DE 0,150 mm A 0,355 mm. TAMBIEN SE REFIERE A UNA COMPOSICION ORAL EN FORMA DE SUSPENSION QUE COMPRENDE COMO DILUYENTE SORBITOL EN SOLUCION Y PROPILENGLICOL
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR9705470A BR9705470A (pt) | 1997-11-12 | 1997-11-12 | Processo para a preparação de uma composição farmaceutica oral composição farmaceutica oral e kit compreendendo uma composição farmacêutica |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20000468A1 true PE20000468A1 (es) | 2000-06-08 |
Family
ID=46799415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1999000382A PE20000468A1 (es) | 1997-11-12 | 1999-05-10 | Proceso para la preparacion de una composicion farmaceutica oral que comprende un antibiotico |
Country Status (1)
| Country | Link |
|---|---|
| PE (1) | PE20000468A1 (es) |
-
1999
- 1999-05-10 PE PE1999000382A patent/PE20000468A1/es not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |