PE105699A1 - Composicion farmaceutica - Google Patents
Composicion farmaceuticaInfo
- Publication number
- PE105699A1 PE105699A1 PE1998000735A PE00073598A PE105699A1 PE 105699 A1 PE105699 A1 PE 105699A1 PE 1998000735 A PE1998000735 A PE 1998000735A PE 00073598 A PE00073598 A PE 00073598A PE 105699 A1 PE105699 A1 PE 105699A1
- Authority
- PE
- Peru
- Prior art keywords
- hydroxyluene
- azaesteroid
- preference
- composition
- acid
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 108010029908 3-oxo-5-alpha-steroid 4-dehydrogenase Proteins 0.000 abstract 1
- 102000001779 3-oxo-5-alpha-steroid 4-dehydrogenase Human genes 0.000 abstract 1
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 1
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 abstract 1
- 239000001828 Gelatine Substances 0.000 abstract 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000004403 Prostatic Hyperplasia Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 229960004217 benzyl alcohol Drugs 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical class [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
SE REFIERE A UNA COMPOSICION QUE COMPRENDE a)4-AZAESTEROIDE o 6-AZAESTEROIDE, DE PREFERENCIA CARBONIL-4-AZAANDROST-1-EN-3-ONA 17-�-SUSTITUIDO o CARBONIL-6-AZAANDROST-1-EN-3-ONA 17-�-SUSTITUIDO; b)UN ESTER DE ACIDO GRASO DE GLICEROL O PROPILENGLICOL, SIENDO LOS ACIDOS CARBOXILICOS DE C6-C12, DE PREFERENCIA ES UN MONOESTER, LA COMPOSICION COMPRENDE ADEMAS UN ANTIOXIDANTE TAL COMO HIDROXITOLUENO BUTILADO, HIDROXIANISOLBUTILADO, ACIDO ASCORBICO O SUS MEZCLAS. LA COMPOSICION SE PRESENTA DE PREFERENCIA EN UNA CAPSULA DE GELATINA BLANDA. EL AZAESTEROIDE ES UN INHIBIDOR DE LA ENZIMA TESTOSTERONA 5-ALFA REDUCTASA, POR LO QUE PUEDE SER UTIL PARA EL TRATAMIENTO DE HIPERPLASIA PROSTATICA BENIGNA, CANCER DE LA PROSTATA
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9717428.8A GB9717428D0 (en) | 1997-08-19 | 1997-08-19 | Pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE105699A1 true PE105699A1 (es) | 1999-11-25 |
Family
ID=10817619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1998000735A PE105699A1 (es) | 1997-08-19 | 1998-08-14 | Composicion farmaceutica |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1007010A2 (es) |
| JP (1) | JP2002511101A (es) |
| KR (1) | KR20010014080A (es) |
| CN (1) | CN1263461A (es) |
| AR (1) | AR016629A1 (es) |
| AU (1) | AU9343098A (es) |
| BR (1) | BR9810458A (es) |
| CA (1) | CA2295016A1 (es) |
| CO (1) | CO4960657A1 (es) |
| GB (1) | GB9717428D0 (es) |
| MA (1) | MA26531A1 (es) |
| PE (1) | PE105699A1 (es) |
| TR (1) | TR199903209T2 (es) |
| WO (1) | WO1999008666A2 (es) |
| ZA (1) | ZA987392B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IS6633A (is) * | 2002-11-22 | 2004-05-23 | Omega Farma Ehf. | Samsetningar af fínasteríð töflum |
| CN102552917A (zh) | 2003-08-13 | 2012-07-11 | 比奥孔有限公司 | 用于治疗剂的微-粒子脂肪酸盐固体剂量制剂 |
| WO2005066195A1 (de) * | 2004-01-02 | 2005-07-21 | Pharmacon Forschung Und Beratung Gmbh | Verfahren zur herstellung von 1,2-ungesättigten azasteroiden |
| WO2006055659A2 (en) * | 2004-11-15 | 2006-05-26 | Smithkline Beecham Corporation | Fixed dose combination op dutasteride and tamsulosin |
| WO2010117873A2 (en) | 2009-04-06 | 2010-10-14 | Banner Pharmacaps, Inc. | Progesterone solutions for increased bioavailability |
| ES2385240B1 (es) | 2010-07-26 | 2013-09-23 | Gp-Pharm, S.A. | Cápsulas de principios activos farmacéuticos y ácidos grasos poliinsaturados para el tratamiento de enfermedades de la próstata. |
| US8900631B2 (en) | 2011-04-28 | 2014-12-02 | Health Science Funding, LLC | Dosage form to increase prasterone bioavailability |
| CN103169712B (zh) * | 2011-12-20 | 2017-10-27 | 重庆华邦制药有限公司 | 提高生物利用度的度他雄胺制剂及其制备方法 |
| WO2014002015A1 (en) | 2012-06-25 | 2014-01-03 | Ranbaxy Laboratories Limited | Pharmaceutical composition comprising dutasteride |
| ES2555485T1 (es) | 2014-05-26 | 2016-01-04 | Galenicum Health S.L. | Composiciones farmacéuticas que contienen un agente activo |
| KR101679992B1 (ko) | 2015-12-31 | 2016-11-28 | 주식회사 유유제약 | 프로필렌글리콜 모노라우레이트를 포함하는 두타스테리드의 약학적 조성물 및 이의 제조 방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571817A (en) * | 1984-02-27 | 1996-11-05 | Merck & Co., Inc. | Methods of treating androgenic alopecia with finasteride [17β-N-mono-substituted-carbamoyl-4-aza-5-α-androst-1-en-ones] |
| DE3607651A1 (de) * | 1986-03-06 | 1987-09-10 | Schering Ag | Kombination von aromatasehemmer und testosteron-5(alpha)-reduktase-hemmer |
| TW369521B (en) * | 1993-09-17 | 1999-09-11 | Smithkline Beecham Corp | Androstenone derivative |
| TW408127B (en) * | 1993-09-17 | 2000-10-11 | Glaxo Inc | Androstenones |
| US5550134A (en) * | 1995-05-10 | 1996-08-27 | Eli Lilly And Company | Methods for inhibiting bone loss |
-
1997
- 1997-08-19 GB GBGB9717428.8A patent/GB9717428D0/en active Pending
-
1998
- 1998-08-12 MA MA25211A patent/MA26531A1/fr unknown
- 1998-08-14 AR ARP980104050A patent/AR016629A1/es unknown
- 1998-08-14 PE PE1998000735A patent/PE105699A1/es not_active Application Discontinuation
- 1998-08-17 BR BR9810458-6A patent/BR9810458A/pt not_active Application Discontinuation
- 1998-08-17 ZA ZA9807392A patent/ZA987392B/xx unknown
- 1998-08-17 TR TR1999/03209T patent/TR199903209T2/xx unknown
- 1998-08-17 AU AU93430/98A patent/AU9343098A/en not_active Abandoned
- 1998-08-17 CN CN98806380A patent/CN1263461A/zh active Pending
- 1998-08-17 KR KR19997012116A patent/KR20010014080A/ko not_active Withdrawn
- 1998-08-17 WO PCT/EP1998/005194 patent/WO1999008666A2/en not_active Ceased
- 1998-08-17 EP EP98946351A patent/EP1007010A2/en not_active Withdrawn
- 1998-08-17 JP JP51280899A patent/JP2002511101A/ja active Pending
- 1998-08-17 CA CA002295016A patent/CA2295016A1/en not_active Abandoned
- 1998-08-18 CO CO98047010A patent/CO4960657A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999008666A3 (en) | 1999-04-15 |
| CN1263461A (zh) | 2000-08-16 |
| KR20010014080A (ko) | 2001-02-26 |
| CO4960657A1 (es) | 2000-09-25 |
| AR016629A1 (es) | 2001-07-25 |
| AU9343098A (en) | 1999-03-08 |
| WO1999008666A2 (en) | 1999-02-25 |
| GB9717428D0 (en) | 1997-10-22 |
| ZA987392B (en) | 2000-02-17 |
| EP1007010A2 (en) | 2000-06-14 |
| BR9810458A (pt) | 2000-09-05 |
| TR199903209T2 (xx) | 2000-05-22 |
| MA26531A1 (fr) | 2004-12-20 |
| CA2295016A1 (en) | 1999-02-25 |
| JP2002511101A (ja) | 2002-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |