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LV11683A - Fenilacetoksitienopiridinu un to starpproduktu - alfa-bromfeniletikskabes atvasinajumu iegusanas panemiens - Google Patents

Fenilacetoksitienopiridinu un to starpproduktu - alfa-bromfeniletikskabes atvasinajumu iegusanas panemiens

Info

Publication number
LV11683A
LV11683A LV960268A LV960268A LV11683A LV 11683 A LV11683 A LV 11683A LV 960268 A LV960268 A LV 960268A LV 960268 A LV960268 A LV 960268A LV 11683 A LV11683 A LV 11683A
Authority
LV
Latvia
Prior art keywords
phenylacetoxytienopyridines
bromophenylchicone
intermediates
saturation
alpha
Prior art date
Application number
LV960268A
Other languages
English (en)
Other versions
LV11683B (en
Inventor
Michel Bouisset
Joel Radisson
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of LV11683A publication Critical patent/LV11683A/lv
Publication of LV11683B publication Critical patent/LV11683B/lv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C07C51/21—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen
    • C07C51/23—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen of oxygen-containing groups to carboxyl groups
    • C07C51/235—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen of oxygen-containing groups to carboxyl groups of —CHO groups or primary alcohol groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
LVP-96-268A 1989-09-29 1996-07-18 A process for the preparation of phenyl-acetoxy-thienopyridines and their intermediate products ¿ alfa-bromo-phenylacetic acid derivatives LV11683B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8912787A FR2652575B1 (fr) 1989-09-29 1989-09-29 Procede de preparation d'acides alpha-bromo phenylacetiques.

Publications (2)

Publication Number Publication Date
LV11683A true LV11683A (lv) 1997-02-20
LV11683B LV11683B (en) 1997-08-20

Family

ID=9385964

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-96-268A LV11683B (en) 1989-09-29 1996-07-18 A process for the preparation of phenyl-acetoxy-thienopyridines and their intermediate products ¿ alfa-bromo-phenylacetic acid derivatives

Country Status (28)

Country Link
US (1) US5036156A (lv)
EP (1) EP0420706B1 (lv)
JP (1) JP3176612B2 (lv)
KR (1) KR910006201A (lv)
AT (1) ATE128961T1 (lv)
AU (1) AU627590B2 (lv)
CA (1) CA2019301C (lv)
DD (1) DD295851A5 (lv)
DE (1) DE69022943T2 (lv)
DK (1) DK0420706T3 (lv)
ES (1) ES2078956T3 (lv)
FI (1) FI903210A7 (lv)
FR (1) FR2652575B1 (lv)
GR (1) GR3017939T3 (lv)
HU (1) HU207325B (lv)
IE (1) IE70432B1 (lv)
IL (1) IL94801A0 (lv)
LV (1) LV11683B (lv)
MA (1) MA21878A1 (lv)
NO (1) NO902714L (lv)
NZ (1) NZ234160A (lv)
OA (1) OA09453A (lv)
PL (1) PL285788A1 (lv)
PT (1) PT94486B (lv)
RU (1) RU1836373C (lv)
TN (1) TNSN90089A1 (lv)
YU (1) YU124590A (lv)
ZA (1) ZA904830B (lv)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5189170A (en) * 1989-09-29 1993-02-23 Sanofi Process for the preparation of phenylacetic derivatives of thieno-pyridines
DE69114024T2 (de) * 1990-01-25 1996-05-30 Sanofi Sa Herstellung von 2-(2'-Thienyl)alkylaminen und deren Derivaten zur Synthese von 4,5,6,7-Thieno[3,2-c]pyridinderivaten.
FR2664596B1 (fr) * 1990-07-10 1994-06-10 Sanofi Sa Procede de preparation d'un derive n-phenylacetique de tetrahydrothieno [3,2-c] pyridine et son intermediaire de synthese.
JP3127332B2 (ja) * 1993-05-10 2001-01-22 本田技研工業株式会社 自動二輪車用制動装置
JP3231169B2 (ja) * 1993-12-30 2001-11-19 本田技研工業株式会社 自動２輪車用制動装置
HU225503B1 (en) * 1997-05-13 2007-01-29 Sanofi Aventis Novel 2-(2-halophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides and process for producing them
HU222283B1 (hu) 1997-05-13 2003-05-28 Sanofi-Synthelabo Eljárás tieno[3,2-c]piridin-származékok előállítására
HU225504B1 (en) 1997-05-13 2007-01-29 Sanofi Aventis Novel halophenyl-(2-(2-thienyl)-ethylamino)-acetonitriles and process for producing them
FR2769313B1 (fr) 1997-10-06 2000-04-21 Sanofi Sa Derives d'esters hydroxyacetiques, leur procede de preparation et leur utilisation comme intermediaires de synthese
EP1353928B1 (en) * 2001-01-24 2006-12-27 Cadila Healthcare Ltd. Process for preparing clopidogrel
US6767913B2 (en) 2001-12-18 2004-07-27 Teva Pharmaceutical Industries Ltd. Crystal forms iii, iv, v, and novel amorphous form of clopidogrel hydrogensulfate, processes for their preparation, processes for the preparation of form i, compositions containing the new forms and methods of administering the new forms
US7074928B2 (en) 2002-01-11 2006-07-11 Teva Pharmaceutical Industries, Ltd. Polymorphs of clopidogrel hydrogensulfate
US6800759B2 (en) * 2002-08-02 2004-10-05 Teva Pharmaceutical Industries Ltd. Racemization and enantiomer separation of clopidogrel
IL166593A0 (en) 2002-08-02 2006-01-15 Racemization and enantiomer separation of clopidogrel
WO2004074215A1 (en) * 2003-02-03 2004-09-02 Sunil Sadanand Nadkarni Process for preparation of clopidogrel, its salts and pharmaceutical compositions
EP1603920A1 (en) 2003-03-12 2005-12-14 Cadila Healthcare Ltd. Polymorph and amorphous form of (s)-(+)-clopidogrel bisulfate
GB0321256D0 (en) 2003-09-11 2003-10-08 Generics Uk Ltd Novel crystalline compounds
ATE455778T1 (de) 2003-11-03 2010-02-15 Cadila Healthcare Ltd Verfahren zur herstellung form i von (s)-(+)- clopidogrelbisulfat
JP2007513889A (ja) * 2004-09-21 2007-05-31 テバ ファーマシューティカル インダストリーズ リミティド 結晶性クロピドグレル臭酸塩及びその調製方法
CA2594763A1 (en) * 2005-02-24 2006-08-31 Teva Pharmaceutical Industries Ltd. Clopidogrel base suitable for pharmaceutical formulation and preparation thereof
WO2006130852A1 (en) * 2005-06-02 2006-12-07 Dr. Reddy's Laboratories Ltd. Recovery of clopidogrel bisulfate
WO2007028337A1 (fr) 2005-09-08 2007-03-15 Zhejiang Huahai Pharmaceutical Co., Ltd. Préparation de clopidogrel et ses composés analogues à base d'acétate de méthyl tétrahydrothiénopyridine
EP1980563A1 (en) 2007-04-09 2008-10-15 BATTULA, Srinivasa Reddy Procedure for the preparation of methyl (+)-(S)-Alpha-(O-chlorophenyl)-6,7-dihydrothieno-[3,2-C]pyridine-5(4H) acetate
EP2084164A2 (en) * 2007-04-18 2009-08-05 Teva Pharmaceutical Industries Ltd. Improved process for preparing clopidogrel
EP2107061A1 (en) 2008-04-02 2009-10-07 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of optically enriched clopidogrel
US20090264460A1 (en) * 2008-04-21 2009-10-22 Mamta Mishra Clopidogrel pharmaceutical formulations
KR100990949B1 (ko) * 2008-06-09 2010-10-29 엔자이텍 주식회사 클로피도그렐 및 그의 유도체의 제조방법
EP2346879A1 (en) * 2008-10-24 2011-07-27 Sandoz AG A process for the preparation of s-clopidogrel
US8563690B2 (en) * 2008-11-03 2013-10-22 The Board Of Trustees Of The University Of Illinois Modulation of platelet aggregation
CN101974016A (zh) * 2010-10-14 2011-02-16 天津药物研究院 酰胺类化合物及其制备方法和用途
CN102250114B (zh) * 2011-04-27 2014-02-26 青岛黄海制药有限责任公司 一种氯吡格雷及其硫酸盐的制备方法
CN102268012B (zh) * 2011-08-24 2014-04-09 天津药物研究院 噻唑衍生物、其制备方法和用途
CN103387497A (zh) * 2012-05-10 2013-11-13 深圳信立泰药业股份有限公司 一种氯吡格雷及其中间体α-溴代邻氯苯乙酸甲酯和噻吩乙胺基取代乙酸甲酯盐的制备方法
CN103450005B (zh) * 2012-06-01 2016-07-06 深圳信立泰药业股份有限公司 一种氯吡格雷及其中间体α-溴代邻氯苯乙酸和α-噻吩乙胺基取代乙酸盐酸盐的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2778851A (en) * 1953-09-03 1957-01-22 Dow Chemical Co Preparation of alpha-chloro-alpha-methyl aliphatic acids and acid-chlorides
JPS5935370B2 (ja) * 1978-11-14 1984-08-28 財団法人相模中央化学研究所 芳香族酢酸の製造方法
US4268442A (en) * 1978-11-14 1981-05-19 Sagami Chemical Research Center Process for preparing aromatic acetic acid
US4289697A (en) 1980-10-15 1981-09-15 American Home Products Corporation 5-Substituted 4-hydroxy-2,3-alkylene thiazolium salts
FR2530247B1 (fr) * 1982-07-13 1986-05-16 Sanofi Sa Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique

Also Published As

Publication number Publication date
GR3017939T3 (en) 1996-02-29
FI903210A7 (fi) 1991-03-30
DD295851A5 (de) 1991-11-14
CA2019301C (en) 2000-09-05
IL94801A0 (en) 1991-04-15
HU903995D0 (en) 1990-11-28
HU207325B (en) 1993-03-29
MA21878A1 (fr) 1990-12-31
NO902714L (no) 1991-04-02
FI903210A0 (fi) 1990-06-26
FR2652575B1 (fr) 1992-01-24
DE69022943D1 (de) 1995-11-16
ZA904830B (en) 1992-02-26
JPH03120286A (ja) 1991-05-22
CA2019301A1 (en) 1991-03-29
AU627590B2 (en) 1992-08-27
IE902179A1 (en) 1991-04-10
EP0420706A2 (fr) 1991-04-03
KR910006201A (ko) 1991-04-27
EP0420706A3 (en) 1992-03-04
PT94486B (pt) 1997-02-28
NO902714D0 (no) 1990-06-19
RU1836373C (ru) 1993-08-23
PT94486A (pt) 1991-05-22
US5036156A (en) 1991-07-30
YU124590A (en) 1991-10-31
DE69022943T2 (de) 1996-04-25
TNSN90089A1 (fr) 1991-03-05
JP3176612B2 (ja) 2001-06-18
FR2652575A1 (fr) 1991-04-05
OA09453A (fr) 1992-10-15
DK0420706T3 (da) 1996-02-05
IE70432B1 (en) 1996-11-27
PL285788A1 (en) 1991-08-12
EP0420706B1 (fr) 1995-10-11
AU5754690A (en) 1991-04-11
HUT55338A (en) 1991-05-28
ATE128961T1 (de) 1995-10-15
NZ234160A (en) 1992-08-26
LV11683B (en) 1997-08-20
ES2078956T3 (es) 1996-01-01

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