[go: up one dir, main page]

LT4508045T - Muskarininio receptoriaus agonisto citrato druskos formos - Google Patents

Muskarininio receptoriaus agonisto citrato druskos formos

Info

Publication number
LT4508045T
LT4508045T LTEPPCT/EP2023/071591T LTEP2023071591T LT4508045T LT 4508045 T LT4508045 T LT 4508045T LT EP2023071591 T LTEP2023071591 T LT EP2023071591T LT 4508045 T LT4508045 T LT 4508045T
Authority
LT
Lithuania
Prior art keywords
receptor agonist
salt forms
muscarinic receptor
citrate salt
citrate
Prior art date
Application number
LTEPPCT/EP2023/071591T
Other languages
English (en)
Inventor
Giles Albert Brown
Paul Mcgee
Julie CANSFIELD
Mark PICKWORTH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB2211399.7A external-priority patent/GB202211399D0/en
Priority claimed from GBGB2305444.8A external-priority patent/GB202305444D0/en
Priority claimed from GBGB2309615.9A external-priority patent/GB202309615D0/en
Application filed filed Critical
Publication of LT4508045T publication Critical patent/LT4508045T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235Saturated compounds containing more than one carboxyl group
    • C07C59/245Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/265Citric acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LTEPPCT/EP2023/071591T 2022-08-04 2023-08-03 Muskarininio receptoriaus agonisto citrato druskos formos LT4508045T (lt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB2211399.7A GB202211399D0 (en) 2022-08-04 2022-08-04 Muscarinic receptor agonists
GBGB2305444.8A GB202305444D0 (en) 2023-04-13 2023-04-13 Muscarinic receptor agonists
GBGB2309615.9A GB202309615D0 (en) 2023-06-26 2023-06-26 Muscarinic receptor agonists
PCT/EP2023/071591 WO2024028458A2 (en) 2022-08-04 2023-08-03 Muscarinic receptor agonists

Publications (1)

Publication Number Publication Date
LT4508045T true LT4508045T (lt) 2025-11-25

Family

ID=87696205

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2023/071591T LT4508045T (lt) 2022-08-04 2023-08-03 Muskarininio receptoriaus agonisto citrato druskos formos

Country Status (27)

Country Link
US (1) US20250340531A1 (lt)
EP (2) EP4663190A2 (lt)
JP (1) JP2025526601A (lt)
KR (1) KR20250041066A (lt)
CN (1) CN119866336A (lt)
AR (1) AR130114A1 (lt)
AU (1) AU2023317835A1 (lt)
CA (1) CA3263797A1 (lt)
CL (1) CL2025000299A1 (lt)
CO (1) CO2025002413A2 (lt)
CR (1) CR20250069A (lt)
DK (1) DK4508045T3 (lt)
DO (1) DOP2025000015A (lt)
ES (1) ES3050097T3 (lt)
FI (1) FI4508045T3 (lt)
HR (1) HRP20251427T1 (lt)
IL (1) IL318739A (lt)
LT (1) LT4508045T (lt)
MA (1) MA69856B1 (lt)
MD (1) MD4508045T2 (lt)
MX (1) MX2025001312A (lt)
PE (1) PE20251236A1 (lt)
PT (1) PT4508045T (lt)
RS (1) RS67422B1 (lt)
SI (1) SI4508045T1 (lt)
TW (1) TW202416955A (lt)
WO (1) WO2024028458A2 (lt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025030095A1 (en) * 2023-08-03 2025-02-06 Neurocrine Biosciences, Inc. Methods of synthesis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2882741B1 (en) * 2012-08-10 2018-10-24 Boehringer Ingelheim International GmbH Heteroaromatic compounds as bruton's tyrosine kinase (btk) inhibitors
SI3406609T1 (sl) 2014-02-06 2024-10-30 Nxera Pharma Uk Limited Biciklične aza spojine kot agonisti muskarinskega receptorja

Also Published As

Publication number Publication date
DK4508045T3 (da) 2025-10-20
CR20250069A (es) 2025-05-26
US20250340531A1 (en) 2025-11-06
EP4508045A2 (en) 2025-02-19
PE20251236A1 (es) 2025-04-29
DOP2025000015A (es) 2025-04-08
CA3263797A1 (en) 2024-02-08
PT4508045T (pt) 2025-10-29
ES3050097T3 (en) 2025-12-19
RS67422B1 (sr) 2025-12-31
AR130114A1 (es) 2024-11-06
AU2023317835A1 (en) 2025-03-20
JP2025526601A (ja) 2025-08-15
KR20250041066A (ko) 2025-03-25
MA69856B1 (fr) 2025-10-31
MX2025001312A (es) 2025-05-02
EP4663190A2 (en) 2025-12-17
CL2025000299A1 (es) 2025-08-08
MD4508045T2 (ro) 2026-01-31
CO2025002413A2 (es) 2025-06-16
HRP20251427T1 (hr) 2025-12-19
TW202416955A (zh) 2024-05-01
IL318739A (en) 2025-03-01
SI4508045T1 (sl) 2025-11-28
WO2024028458A2 (en) 2024-02-08
FI4508045T3 (fi) 2025-11-13
CN119866336A (zh) 2025-04-22
EP4508045B1 (en) 2025-10-01
WO2024028458A3 (en) 2024-03-21

Similar Documents

Publication Publication Date Title
LT4508045T (lt) Muskarininio receptoriaus agonisto citrato druskos formos
HRP20130468T1 (en) Diamide compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity
IL281393A (en) Formulations for oral administration of kappa opioid receptor agonists
ZA200802586B (en) Dihyrdogen phosphate salt of a prostaglandin D2 receptor antagonist
LT4313945T (lt) Kristalinė 5-meo-dmt hidrobromido druska
IL281464A (en) Crystal forms of a paranoid X receptor agonist
EP4130005A4 (en) CRYSTALLINE FORM A OF A GLP-1 RECEPTOR AGONIST AND METHOD OF MANUFACTURING THEREOF
IL312637A (en) Treatment of liver disorders with a thr-β agonist
EP4455141A4 (en) PHARMACEUTICALLY ACCEPTABLE SALT AND CRYSTALLINE FORM OF GLP-1 RECEPTOR AGONIST AND PROCESS FOR PREPARATION THEREOF
EP4019496A4 (en) SALT AND CRYSTAL FORM OF A COMPOUND WITH AGONISTIC ACTION ON S1P5 RECEPTOR
EP4013398A4 (en) IMPROVED METHOD FOR PRODUCING VILANTEROL OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
IL184395A0 (en) Novel salt form of a dopamine agonist
MY197142A (en) Gonadotropin-releasing hormone receptor antagonist and use thereof
GB2593902B (en) Salt of a pharmaceutical compound
GB202301180D0 (en) Salt of a pharmaceutical compound
EP4306516A4 (en) NEW METHOD FOR THE PRODUCTION OF A SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST
LT4041388T (lt) Prostaglandino ep4 receptoriaus antagonisto junginiai
EP4431488A4 (en) PROCESS FOR PREPARING DOPAMINE HYDROCHLORIDE
GB202211234D0 (en) Prostaglandin EP4 receptor agonist compounds
GB202309615D0 (en) Muscarinic receptor agonists
GB202305444D0 (en) Muscarinic receptor agonists
GB202003100D0 (en) Salts and polymorphic forms of compound a
CA3287403A1 (en) Polymorph form of pitolisant hydrochloride
GB201909012D0 (en) Prostaglandin EP4 receptor agonist compounds
GB201909004D0 (en) Prostaglandin EP4 receptor agonist compounds