LT3601297T - Junginiai, kurie slopina mcl-1 baltymą - Google Patents
Junginiai, kurie slopina mcl-1 baltymąInfo
- Publication number
- LT3601297T LT3601297T LTEPPCT/US2018/024723T LT18024723T LT3601297T LT 3601297 T LT3601297 T LT 3601297T LT 18024723 T LT18024723 T LT 18024723T LT 3601297 T LT3601297 T LT 3601297T
- Authority
- LT
- Lithuania
- Prior art keywords
- protein
- compounds
- inhibit mcl
- mcl
- inhibit
- Prior art date
Links
- 101001056180 Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1 Proteins 0.000 title 1
- 102100026539 Induced myeloid leukemia cell differentiation protein Mcl-1 Human genes 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762479230P | 2017-03-30 | 2017-03-30 | |
| US201762479171P | 2017-03-30 | 2017-03-30 | |
| PCT/US2018/024723 WO2018183418A1 (en) | 2017-03-30 | 2018-03-28 | Compounds that inhibit mcl-1 protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3601297T true LT3601297T (lt) | 2022-12-12 |
Family
ID=61972255
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEPPCT/US2018/024723T LT3601297T (lt) | 2017-03-30 | 2018-03-28 | Junginiai, kurie slopina mcl-1 baltymą |
Country Status (35)
| Country | Link |
|---|---|
| US (5) | US10300075B2 (lt) |
| EP (1) | EP3601297B9 (lt) |
| JP (2) | JP6453507B2 (lt) |
| KR (1) | KR102372322B1 (lt) |
| CN (1) | CN110691784B (lt) |
| AU (2) | AU2018244349B2 (lt) |
| BR (1) | BR112019020459B1 (lt) |
| CA (1) | CA3057882A1 (lt) |
| CL (1) | CL2019002777A1 (lt) |
| CO (1) | CO2019011762A2 (lt) |
| CR (1) | CR20190489A (lt) |
| DK (1) | DK3601297T5 (lt) |
| ES (1) | ES2940641T3 (lt) |
| FI (1) | FI3601297T3 (lt) |
| HR (1) | HRP20221412T2 (lt) |
| HU (1) | HUE060919T2 (lt) |
| IL (1) | IL269603B (lt) |
| JO (1) | JOP20190229B1 (lt) |
| LT (1) | LT3601297T (lt) |
| MX (1) | MX389487B (lt) |
| MY (1) | MY204294A (lt) |
| NZ (1) | NZ757606A (lt) |
| PE (1) | PE20200335A1 (lt) |
| PH (1) | PH12019502245A1 (lt) |
| PL (1) | PL3601297T3 (lt) |
| PT (1) | PT3601297T (lt) |
| RS (1) | RS63892B9 (lt) |
| SA (1) | SA519410222B1 (lt) |
| SG (1) | SG11201908945RA (lt) |
| SI (1) | SI3601297T1 (lt) |
| SM (1) | SMT202300122T1 (lt) |
| TW (1) | TWI685493B (lt) |
| UA (1) | UA124784C2 (lt) |
| UY (1) | UY37656A (lt) |
| WO (1) | WO2018183418A1 (lt) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2971271T3 (es) | 2017-01-20 | 2024-06-04 | Arcus Biosciences Inc | Azolopirimidina para el tratamiento de trastornos relacionados con el cáncer |
| JOP20180029A1 (ar) | 2017-03-30 | 2019-01-30 | Takeda Pharmaceuticals Co | مركب حلقي غير متجانس |
| WO2018183964A1 (en) | 2017-03-30 | 2018-10-04 | Genentech, Inc. | Isoquinolines as inhibitors of hpk1 |
| JP6453507B2 (ja) | 2017-03-30 | 2019-01-16 | アムジエン・インコーポレーテツド | Ｍｃｌ−１タンパク質を阻害する化合物 |
| EP3668878B1 (en) | 2017-08-18 | 2025-05-21 | Amgen Inc. | Compounds that inhibit mcl-1 protein |
| US11279712B2 (en) | 2017-08-29 | 2022-03-22 | Amgen Inc. | Macrocyclic compounds that inhibit MCL-1 protein |
| US12041084B2 (en) | 2018-02-09 | 2024-07-16 | Bolster, Inc | Systems and methods for determining user intent at a website and responding to the user intent |
| US11301560B2 (en) * | 2018-02-09 | 2022-04-12 | Bolster, Inc | Real-time detection and blocking of counterfeit websites |
| US11271966B2 (en) * | 2018-02-09 | 2022-03-08 | Bolster, Inc | Real-time detection and redirecton from counterfeit websites |
| US11478479B2 (en) | 2018-02-16 | 2022-10-25 | Arcus Biosciences, Inc. | Dosing with an azolopyrimidine compound |
| US11274105B2 (en) | 2018-03-05 | 2022-03-15 | Amgen Inc. | Alpha-hydroxy phenylacetic acid pharmacophore or bioisostere Mcl-1 protein antagonists |
| EP3793565B1 (en) | 2018-05-14 | 2022-01-05 | Gilead Sciences, Inc. | Mcl-1 inhibitors |
| TW202019905A (zh) | 2018-07-24 | 2020-06-01 | 瑞士商赫孚孟拉羅股份公司 | 異喹啉化合物及其用途 |
| TW202024053A (zh) | 2018-10-02 | 2020-07-01 | 美商建南德克公司 | 異喹啉化合物及其用途 |
| US11612606B2 (en) | 2018-10-03 | 2023-03-28 | Genentech, Inc. | 8-aminoisoquinoline compounds and uses thereof |
| CN113166173A (zh) * | 2018-11-09 | 2021-07-23 | 普莱鲁德疗法有限公司 | 作为骨髓细胞白血病1(mcl-1)蛋白抑制剂的螺-磺酰胺衍生物 |
| EP3781574B1 (en) | 2019-01-18 | 2023-05-10 | Ascentage Pharma (Suzhou) Co., Ltd. | Macrocyclic spiroethers as mcl-1 inhibitors |
| EP3781575A4 (en) | 2019-01-23 | 2021-06-02 | Ascentage Pharma (Suzhou) Co., Ltd. | MACROCYCLIC FUSION PYRRAZOLES USED AS MCL-1 INHIBITORS |
| EP3972651A2 (en) | 2019-05-20 | 2022-03-30 | Novartis AG | Mcl-1 inhibitor antibody-drug conjugates and methods of use |
| US11453681B2 (en) | 2019-05-23 | 2022-09-27 | Gilead Sciences, Inc. | Substituted eneoxindoles and uses thereof |
| CN114245807B (zh) | 2019-06-25 | 2025-05-02 | 吉利德科学公司 | Flt3l-fc融合蛋白和使用方法 |
| CA3144558A1 (en) | 2019-07-09 | 2021-01-14 | Janssen Pharmaceutica Nv | Macrocyclic spirocycle derivatives as mcl-1 inhibitors |
| PH12022550835A1 (en) | 2019-10-18 | 2023-07-03 | Forty Seven Inc | Combination therapies for treating myelodysplastic syndromes and acute myeloid leukemia |
| MY209360A (en) | 2019-10-31 | 2025-07-03 | Forty Seven Llc | Anti-cd47 and anti-cd20 based treatment of blood cancer |
| TWI778443B (zh) | 2019-11-12 | 2022-09-21 | 美商基利科學股份有限公司 | Mcl1抑制劑 |
| AU2020391106B2 (en) | 2019-11-26 | 2024-03-21 | Gilead Sciences, Inc. | Processes and intermediates for preparing MCL1 inhibitors |
| CN117736207A (zh) | 2019-12-24 | 2024-03-22 | 卡尔那生物科学株式会社 | 二酰基甘油激酶调节化合物 |
| AU2021219668B2 (en) | 2020-02-14 | 2025-06-12 | Gilead Sciences, Inc. | Antibodies and fusion proteins that bind to CCR8 and uses thereof |
| JP2021161114A (ja) * | 2020-03-31 | 2021-10-11 | アムジエン・インコーポレーテツド | Ｍｃｌ−１化合物のメチル化 |
| WO2021211922A1 (en) * | 2020-04-16 | 2021-10-21 | Prelude Therapeutics, Incorporated | Spiro-sulfonimidamide derivatives as inhibitors of myeloid cell leukemia-1 (mcl-1) protein |
| CA3181922A1 (en) | 2020-05-01 | 2021-11-04 | Gilead Sciences, Inc. | Cd73 inhibiting 2,4-dioxopyrimidine compounds |
| CA3181189A1 (en) * | 2020-05-06 | 2021-11-11 | Amgen Inc. | Synthesis of vinylic alcohol intermediates |
| ES3038201T3 (en) * | 2020-05-06 | 2025-10-10 | Amgen Inc | Synthesis of vinylic protected alcohol intermediates |
| TWI827924B (zh) | 2020-05-06 | 2024-01-01 | 美商安進公司 | 大環Mcl-1抑制劑中間體的閉環合成 |
| TWI867217B (zh) | 2020-05-06 | 2024-12-21 | 美商安進公司 | 乙烯基環丁基中間體之合成 |
| US12441681B2 (en) | 2020-05-06 | 2025-10-14 | Amgen Inc. | Synthesis of sulfonamide intermediates |
| AU2021271694A1 (en) * | 2020-05-13 | 2023-01-19 | Prelude Therapeutics, Incorporated | Spiro-sulfonamide derivatives as inhibitors of Myeloid Cell Leukemia-1 (MCL-1) protein |
| CA3180387A1 (en) | 2020-06-10 | 2021-12-16 | Soufyan JERHAOUI | Macrocyclic 2-amino-3-fluoro-but-3-enamides as inhibitors of mcl-1 |
| JP2022039996A (ja) * | 2020-08-26 | 2022-03-10 | アムジエン・インコーポレーテツド | Ｍｃｌ－１阻害剤処方物 |
| MX2023002691A (es) * | 2020-09-03 | 2023-05-03 | Amgen Inc | Desimetrización de diol mediante sustitución aromática nucleófila. |
| JP7659630B2 (ja) * | 2020-11-19 | 2025-04-09 | ギリアード サイエンシーズ， インコーポレイテッド | 大環状ｍｃｌ１阻害剤を調製するための方法及び中間体 |
| US20240042051A1 (en) | 2020-11-24 | 2024-02-08 | Francesca Rocchetti | Mcl-1 inhibitor antibody-drug conjugates and methods of use |
| KR20230113577A (ko) | 2020-11-25 | 2023-07-31 | 암젠 인크 | 알데히드의 거울상이성질체 선택적 알케닐화 |
| MX2023007297A (es) | 2020-12-17 | 2023-07-04 | Janssen Pharmaceutica Nv | 3-fluoro-but-3-enamidas ramificadas macrociclicas como inhibidores de mcl-1. |
| TW202302145A (zh) | 2021-04-14 | 2023-01-16 | 美商基利科學股份有限公司 | ＣＤ４７／ＳＩＲＰα結合及ＮＥＤＤ８活化酶Ｅ１調節次單元之共抑制以用於治療癌症 |
| CN117295749A (zh) | 2021-04-26 | 2023-12-26 | 詹森药业有限公司 | 作为mcl-1抑制剂的大环2-烯丙基四氢呋喃 |
| US20220389394A1 (en) | 2021-05-18 | 2022-12-08 | Gilead Sciences, Inc. | METHODS OF USING FLT3L-Fc FUSION PROTEINS |
| TWI861509B (zh) | 2021-06-11 | 2024-11-11 | 美商基利科學股份有限公司 | Mcl-1抑制劑與抗體藥物接合物之組合 |
| JP2024520801A (ja) | 2021-06-11 | 2024-05-24 | ギリアード サイエンシーズ， インコーポレイテッド | Ｍｃｌ－１阻害剤と抗がん剤との組み合わせ |
| AU2022298639C1 (en) | 2021-06-23 | 2025-07-17 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| JP7654118B2 (ja) | 2021-06-23 | 2025-03-31 | ギリアード サイエンシーズ， インコーポレイテッド | ジアシルグリセロールキナーゼ調節化合物 |
| KR20240025616A (ko) | 2021-06-23 | 2024-02-27 | 길리애드 사이언시즈, 인코포레이티드 | 다이아실글리세롤 키나제 조절 화합물 |
| KR20240005901A (ko) | 2021-06-23 | 2024-01-12 | 길리애드 사이언시즈, 인코포레이티드 | 디아실글리세롤 키나제 조절 화합물 |
| US20240401146A1 (en) | 2021-10-06 | 2024-12-05 | Institut National de la Santé et de la Recherche Médicale | Methods for predicting and improving the efficacy of mcl-1 inhibitor therapy |
| CN118139858A (zh) | 2021-10-28 | 2024-06-04 | 吉利德科学公司 | 吡地嗪-3(2h)-酮衍生物 |
| WO2023077030A1 (en) | 2021-10-29 | 2023-05-04 | Gilead Sciences, Inc. | Cd73 compounds |
| JP2024544570A (ja) | 2021-11-16 | 2024-12-03 | ヤンセン ファーマシューティカ エヌ．ベー． | Ｍｃｌ－１阻害剤としての大環状２－アミノ－ブト－３－エナミド |
| US20230220106A1 (en) | 2021-12-08 | 2023-07-13 | Dragonfly Therapeutics, Inc. | Antibodies targeting 5t4 and uses thereof |
| US20230203202A1 (en) | 2021-12-08 | 2023-06-29 | Dragonfly Therapeutics, Inc. | Proteins binding nkg2d, cd16 and 5t4 |
| EP4452414A2 (en) | 2021-12-22 | 2024-10-30 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof |
| WO2023122615A1 (en) | 2021-12-22 | 2023-06-29 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof |
| TW202340168A (zh) | 2022-01-28 | 2023-10-16 | 美商基利科學股份有限公司 | Ｐａｒｐ７抑制劑 |
| CA3246092A1 (en) | 2022-02-04 | 2023-08-10 | Amgen Inc. | CRYSTALLINE FORMS OF AN MCL-1 INHIBITOR |
| JP2025505142A (ja) | 2022-02-04 | 2025-02-21 | アムジエン・インコーポレーテツド | ムリザトクラクス（ａｍｇ３９７）の結晶塩及び溶媒和物形態 |
| ES2999273T3 (en) | 2022-03-17 | 2025-02-25 | Gilead Sciences Inc | Ikaros zinc finger family degraders and uses thereof |
| CN119031937A (zh) | 2022-03-24 | 2024-11-26 | 吉利德科学公司 | 用于治疗表达Trop-2的癌症的联合疗法 |
| TWI876305B (zh) | 2022-04-05 | 2025-03-11 | 美商基利科學股份有限公司 | 用於治療結腸直腸癌之組合療法 |
| KR20250004824A (ko) | 2022-04-21 | 2025-01-08 | 길리애드 사이언시즈, 인코포레이티드 | Kras g12d 조절 화합물 |
| WO2023225359A1 (en) | 2022-05-20 | 2023-11-23 | Novartis Ag | Antibody-drug conjugates of antineoplastic compounds and methods of use thereof |
| IL317958A (en) | 2022-07-01 | 2025-02-01 | Gilead Sciences Inc | CD73 compounds |
| US20240091351A1 (en) | 2022-09-21 | 2024-03-21 | Gilead Sciences, Inc. | FOCAL IONIZING RADIATION AND CD47/SIRPa DISRUPTION ANTICANCER COMBINATION THERAPY |
| US20240254118A1 (en) | 2022-12-22 | 2024-08-01 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| EP4695260A1 (en) | 2023-04-11 | 2026-02-18 | Gilead Sciences, Inc. | Kras modulating compounds |
| KR20250175331A (ko) | 2023-04-21 | 2025-12-16 | 길리애드 사이언시즈, 인코포레이티드 | Prmt5 억제제 및 이의 용도 |
| US20250042922A1 (en) | 2023-06-30 | 2025-02-06 | Gilead Sciences, Inc. | Kras modulating compounds |
| US20250066328A1 (en) | 2023-07-26 | 2025-02-27 | Gilead Sciences, Inc. | Parp7 inhibitors |
| AU2024297978A1 (en) | 2023-07-26 | 2026-02-05 | Gilead Sciences, Inc. | Parp7 inhibitors |
| EP4516807A1 (en) | 2023-08-28 | 2025-03-05 | Consorcio Centro de Investigación Biomédica en Red | Compositions for use in a method of providing improved hematopoietic stem cell engraftment |
| US20250101042A1 (en) | 2023-09-08 | 2025-03-27 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
| US20250109147A1 (en) | 2023-09-08 | 2025-04-03 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
| WO2025096589A1 (en) | 2023-11-03 | 2025-05-08 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| WO2025111450A1 (en) | 2023-11-22 | 2025-05-30 | Les Laboratoires Servier | Anti-cd74 antibody-drug conjugates and methods of use thereof |
| WO2025111431A1 (en) | 2023-11-22 | 2025-05-30 | Les Laboratoires Servier | Anti-cd7 antibody-drug conjugates and methods of use thereof |
| WO2025126157A1 (en) | 2023-12-15 | 2025-06-19 | Advesya | Anti-il-1rap binding domains and antibody-drug conjugates thereof |
| WO2025137640A1 (en) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
| WO2025245003A1 (en) | 2024-05-21 | 2025-11-27 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US5858784A (en) | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
| US6042820A (en) | 1996-12-20 | 2000-03-28 | Connaught Laboratories Limited | Biodegradable copolymer containing α-hydroxy acid and α-amino acid units |
| US6472375B1 (en) | 1998-04-16 | 2002-10-29 | John Wayne Cancer Institute | DNA vaccine and methods for its use |
| CA2682356C (en) | 2007-04-16 | 2016-06-14 | Abbott Laboratories | 7-substituted indole mcl-1 inhibitors |
| EP3138838A1 (en) | 2010-01-29 | 2017-03-08 | Dana-Farber Cancer Institute, Inc. | Small molecules for the modulation of mcl-1 and methods of modulating cell death, cell division, cell differentiation and methods of treating disorders |
| KR102591242B1 (ko) | 2011-08-31 | 2023-10-19 | 애버리 데니슨 코포레이션 | 접착성 아크릴레이트-올레핀 코폴리머, 이것의 제조방법, 및 이것을 사용하는 조성물 |
| WO2013052943A2 (en) | 2011-10-06 | 2013-04-11 | The Regents Of The University Of Michgian | Small molecule inhibitors of mcl-1 and uses thereof |
| US9914723B2 (en) | 2012-03-29 | 2018-03-13 | The Regents Of The University Of Michigan | Small molecule inhibitors of Mcl-1 and uses thereof |
| US10533010B2 (en) * | 2014-03-27 | 2020-01-14 | Vanderbilt University | Substituted indole Mcl-1 inhibitors |
| JO3474B1 (ar) | 2014-08-29 | 2020-07-05 | Amgen Inc | مشتقات تيتراهيدرونافثالين التي تثبط بروتين mcl-1 |
| US11306107B2 (en) * | 2016-02-25 | 2022-04-19 | Amgen Inc. | Compounds that inhibit MCL-1 protein |
| JP6786892B2 (ja) | 2016-06-09 | 2020-11-18 | 富士ゼロックス株式会社 | サーバ装置、情報処理システム及びプログラム |
| JP6453507B2 (ja) * | 2017-03-30 | 2019-01-16 | アムジエン・インコーポレーテツド | Ｍｃｌ−１タンパク質を阻害する化合物 |
| EP3668878B1 (en) | 2017-08-18 | 2025-05-21 | Amgen Inc. | Compounds that inhibit mcl-1 protein |
| US11279712B2 (en) | 2017-08-29 | 2022-03-22 | Amgen Inc. | Macrocyclic compounds that inhibit MCL-1 protein |
-
2018
- 2018-03-27 JP JP2018059341A patent/JP6453507B2/ja active Active
- 2018-03-28 PL PL18717811.6T patent/PL3601297T3/pl unknown
- 2018-03-28 HR HRP20221412TT patent/HRP20221412T2/hr unknown
- 2018-03-28 ES ES18717811T patent/ES2940641T3/es active Active
- 2018-03-28 MX MX2019011693A patent/MX389487B/es unknown
- 2018-03-28 PT PT187178116T patent/PT3601297T/pt unknown
- 2018-03-28 SG SG11201908945R patent/SG11201908945RA/en unknown
- 2018-03-28 CR CR20190489A patent/CR20190489A/es unknown
- 2018-03-28 UA UAA201910703A patent/UA124784C2/uk unknown
- 2018-03-28 US US15/938,001 patent/US10300075B2/en active Active
- 2018-03-28 HU HUE18717811A patent/HUE060919T2/hu unknown
- 2018-03-28 WO PCT/US2018/024723 patent/WO2018183418A1/en not_active Ceased
- 2018-03-28 CA CA3057882A patent/CA3057882A1/en active Pending
- 2018-03-28 KR KR1020197029091A patent/KR102372322B1/ko active Active
- 2018-03-28 NZ NZ757606A patent/NZ757606A/en unknown
- 2018-03-28 MY MYPI2019005626A patent/MY204294A/en unknown
- 2018-03-28 FI FIEP18717811.6T patent/FI3601297T3/fi active
- 2018-03-28 SM SM20230122T patent/SMT202300122T1/it unknown
- 2018-03-28 BR BR112019020459-8A patent/BR112019020459B1/pt active IP Right Grant
- 2018-03-28 LT LTEPPCT/US2018/024723T patent/LT3601297T/lt unknown
- 2018-03-28 SI SI201830809T patent/SI3601297T1/sl unknown
- 2018-03-28 RS RS20230036A patent/RS63892B9/sr unknown
- 2018-03-28 AU AU2018244349A patent/AU2018244349B2/en active Active
- 2018-03-28 CN CN201880035818.3A patent/CN110691784B/zh active Active
- 2018-03-28 JO JOP/2019/0229A patent/JOP20190229B1/ar active
- 2018-03-28 PE PE2019001963A patent/PE20200335A1/es unknown
- 2018-03-28 EP EP18717811.6A patent/EP3601297B9/en active Active
- 2018-03-28 DK DK18717811.6T patent/DK3601297T5/da active
- 2018-03-30 TW TW107111110A patent/TWI685493B/zh active
- 2018-04-02 UY UY0001037656A patent/UY37656A/es not_active Application Discontinuation
- 2018-12-11 JP JP2018231352A patent/JP6629419B2/ja active Active
-
2019
- 2019-03-11 US US16/297,904 patent/US10500213B2/en active Active
- 2019-08-22 US US16/547,747 patent/US10632128B2/en active Active
- 2019-09-24 IL IL269603A patent/IL269603B/en unknown
- 2019-09-27 PH PH12019502245A patent/PH12019502245A1/en unknown
- 2019-09-27 CL CL2019002777A patent/CL2019002777A1/es unknown
- 2019-09-30 SA SA519410222A patent/SA519410222B1/ar unknown
- 2019-10-24 CO CONC2019/0011762A patent/CO2019011762A2/es unknown
-
2020
- 2020-02-06 US US16/783,269 patent/US10821115B2/en active Active
- 2020-09-23 US US17/029,249 patent/US11224601B1/en active Active
-
2021
- 2021-01-15 AU AU2021200233A patent/AU2021200233A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| LT3601297T (lt) | Junginiai, kurie slopina mcl-1 baltymą | |
| DK3761790T3 (da) | Picolinamider som fungicider | |
| LT3810602T (lt) | Junginiai | |
| DK3668855T3 (da) | Herbicide forbindelser | |
| EP3578560A4 (en) | QUINAZOLINE COMPOUND | |
| EP3592149A4 (en) | FUNGICIDE COMBINATIONS | |
| EP3609871A4 (en) | ARYL CYCLOPROPYL-AMINO-ISOQUINOLINYL AMIDE COMPOUNDS | |
| LT3298027T (lt) | Antihelmintiniai depsipeptido junginiai | |
| MA49908A (fr) | Composés inhibant la protéine mcl-1 | |
| EP3713931C0 (en) | 3-OXO-6-HETEROARYL-2-PHENYL-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDE | |
| DK4039675T3 (da) | Phenyl-2-hydroxy-acetylamino-2-methyl-phenyl forbindelser | |
| BR112017023150A2 (pt) | compostos herbicidas. | |
| EP3467106A4 (en) | PEPTIDE COMPOUND | |
| HUE065134T2 (hu) | Vegyületek | |
| EP3614845A4 (en) | FUNGICIDE COMBINATIONS | |
| LT3347360T (lt) | Junginiai, naudingi ror-gama-t slopinimui | |
| LT3253749T (lt) | Junginiai, pasižymintys priešnavikiniu aktyvumu | |
| EP3604612A4 (en) | Tungsten target | |
| DK3728220T3 (da) | Farmaceutiske forbindelser | |
| DK3672941T3 (da) | Pyridylpyridonforbindelser | |
| IT201700080068A1 (it) | Peptidi antimicrobici | |
| DK3672962T3 (da) | Morpholinylpyridonforbindelser | |
| HUE056928T2 (hu) | Új vegyületek | |
| DK3412667T3 (da) | Cokrystal | |
| BR112017022809A2 (pt) | compostos herbicidas. |