LT3468975T - Nauji antibakteriniai junginiai - Google Patents
Nauji antibakteriniai junginiaiInfo
- Publication number
- LT3468975T LT3468975T LTEP17732775.6T LT17732775T LT3468975T LT 3468975 T LT3468975 T LT 3468975T LT 17732775 T LT17732775 T LT 17732775T LT 3468975 T LT3468975 T LT 3468975T
- Authority
- LT
- Lithuania
- Prior art keywords
- antibacterial compounds
- new antibacterial
- new
- compounds
- antibacterial
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16173550 | 2016-06-08 | ||
| PCT/EP2017/063600 WO2017211759A1 (en) | 2016-06-08 | 2017-06-05 | New antibacterial compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3468975T true LT3468975T (lt) | 2020-08-10 |
Family
ID=56116327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP17732775.6T LT3468975T (lt) | 2016-06-08 | 2017-06-05 | Nauji antibakteriniai junginiai |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US10633366B2 (lt) |
| EP (2) | EP3468975B1 (lt) |
| JP (2) | JP2019517545A (lt) |
| KR (2) | KR20190019084A (lt) |
| CN (2) | CN109415373A (lt) |
| AR (2) | AR108777A1 (lt) |
| AU (2) | AU2017276627A1 (lt) |
| BR (2) | BR112018075334A2 (lt) |
| CA (2) | CA3025270A1 (lt) |
| CY (1) | CY1123194T1 (lt) |
| DK (1) | DK3468975T3 (lt) |
| EA (2) | EA201892815A1 (lt) |
| ES (1) | ES2802233T3 (lt) |
| HR (1) | HRP20200894T1 (lt) |
| HU (1) | HUE049547T2 (lt) |
| IL (2) | IL263283A (lt) |
| LT (1) | LT3468975T (lt) |
| MA (1) | MA45221A (lt) |
| MD (1) | MD3468975T2 (lt) |
| ME (1) | ME03738B (lt) |
| MX (2) | MX2018015126A (lt) |
| PL (1) | PL3468975T3 (lt) |
| PT (1) | PT3468975T (lt) |
| RS (1) | RS60511B1 (lt) |
| SG (2) | SG11201810352XA (lt) |
| SI (1) | SI3468975T1 (lt) |
| SM (1) | SMT202000335T1 (lt) |
| WO (2) | WO2017211760A1 (lt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3468975T3 (pl) * | 2016-06-08 | 2020-09-07 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | Nowe związki przeciwbakteryjne |
| WO2021161148A1 (en) | 2020-02-10 | 2021-08-19 | Virox Technologies Inc. | Antimicrobial compositions containing peroxyphthalic acid and/or salt thereof |
| IL302990A (en) | 2020-11-23 | 2023-07-01 | Enanta Pharm Inc | Novel spiropyrrolidine derived antiviral agents |
| WO2022235605A1 (en) | 2021-05-04 | 2022-11-10 | Enanta Pharmaceuticals, Inc. | Novel macrocyclic antiviral agents |
| CN113698412A (zh) * | 2021-09-01 | 2021-11-26 | 临沂大学 | 一种香豆素并[4,3-b]吡咯类衍生物及其合成方法和应用 |
| WO2023086350A1 (en) | 2021-11-12 | 2023-05-19 | Enanta Pharmaceuticals, Inc. | Alkyne-containing antiviral agents |
| US11919910B2 (en) | 2021-11-12 | 2024-03-05 | Enanta Pharmaceuticals, Inc. | Spiropyrrolidine derived antiviral agents |
| US11912714B2 (en) | 2021-11-12 | 2024-02-27 | Enanta Pharmaceuticals, Inc. | Spiropyrrolidine derived antiviral agents |
| WO2023107419A1 (en) | 2021-12-08 | 2023-06-15 | Enanta Pharmaceuticals, Inc. | Saturated spirocyclics as antiviral agents |
| WO2023137007A1 (en) * | 2022-01-11 | 2023-07-20 | Enanta Pharmaceuticals, Inc. | Processes for the preparation of 4,6,7-trifluoro-1h-indole-2-carboxylic acid |
| WO2023196307A1 (en) | 2022-04-05 | 2023-10-12 | Enanta Pharmaceuticals, Inc. | Novel spiropyrrolidine derived antiviral agents |
| CN115850672B (zh) * | 2022-11-25 | 2024-07-19 | 浙江甬仑聚嘉新材料有限公司 | 一种液晶聚合物及其制备方法和应用 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2886570B2 (ja) * | 1989-09-29 | 1999-04-26 | エーザイ株式会社 | 縮合ヘテロ環を有する化合物 |
| AU645681B2 (en) * | 1991-05-02 | 1994-01-20 | John Wyeth & Brother Limited | Piperazine derivatives |
| US5607936A (en) | 1994-09-30 | 1997-03-04 | Merck & Co., Inc. | Substituted aryl piperazines as neurokinin antagonists |
| FR2822154B1 (fr) | 2001-03-13 | 2005-10-21 | Aventis Pharma Sa | Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent |
| CA2488635C (en) * | 2002-06-12 | 2012-10-23 | Abbott Laboratories | Antagonists of melanin concentrating hormone receptor |
| DE102004041163A1 (de) | 2004-08-25 | 2006-03-02 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
| JP5314244B2 (ja) * | 2004-10-27 | 2013-10-16 | 富山化学工業株式会社 | 新規な含窒素複素環化合物およびその塩 |
| US7842810B2 (en) | 2005-03-31 | 2010-11-30 | Janssen Pharmaceutica, Nv | Bicyclic pyrazole compounds as antibacterial agents |
| CA2608072A1 (en) * | 2005-05-24 | 2006-11-30 | Astrazeneca Ab | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity |
| MY150958A (en) * | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| US8329694B2 (en) * | 2005-06-24 | 2012-12-11 | Toyama Chemical Co., Ltd. | Quinoxalinones as antibacterial composition |
| CN101346379A (zh) * | 2005-10-21 | 2009-01-14 | 葛兰素集团有限公司 | 用作抗菌剂的周环并合的三环化合物 |
| KR20120011093A (ko) * | 2007-05-09 | 2012-02-06 | 화이자 인코포레이티드 | 치환된 헤테로사이클릭 유도체 및 조성물 및 항균제로서의 이의 약학적 용도 |
| JP5620636B2 (ja) * | 2007-11-26 | 2014-11-05 | 富山化学工業株式会社 | 新規な複素環化合物またはその塩を含有する抗菌剤 |
| US20110071155A1 (en) * | 2008-05-23 | 2011-03-24 | Carlos Alemparte-Gallardo | Tricyclic Nitrogen Containing Compounds And Their Use As Antibacterials |
| CN102105473B (zh) * | 2008-05-23 | 2013-05-08 | 葛兰素集团有限公司 | 三环含氮化合物及其作为抗菌剂的用途 |
| TW201022279A (en) * | 2008-11-14 | 2010-06-16 | Astrazeneca Ab | Chemical compounds |
| EP2379554B1 (en) * | 2009-01-15 | 2015-11-11 | Glaxo Group Limited | Naphthyridin-2(1h)-one compounds useful as antibacterials |
| CA2750047A1 (en) | 2009-01-21 | 2010-07-29 | Basilea Pharmaceutica Ag | Novel bicyclic antibiotics |
| US9156822B2 (en) | 2010-07-02 | 2015-10-13 | The University Of North Carolina At Chapel Hill | Functionally selective ligands of dopamine D2 receptors |
| WO2012117421A1 (en) * | 2011-03-02 | 2012-09-07 | Orchid Research Laboratories Ltd | Histone deacetylase inhibitors |
| EP2723737A1 (en) * | 2011-06-27 | 2014-04-30 | Kyorin Pharmaceutical Co., Ltd. | Bridged bicyclic compounds for the treatment of bacterial infections |
| JP6030146B2 (ja) | 2011-11-08 | 2016-11-24 | アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ | ２−オキソ−オキサゾリジン−３，５−ジイル抗生物質誘導体 |
| US9029368B2 (en) | 2011-11-30 | 2015-05-12 | Actelion Pharmaceuticals Ltd. | 3,7-disubstituted octahydro-2H-pyrido[4,3-E][1,3]oxazin-2-one antibiotics |
| CN105218501A (zh) * | 2014-07-03 | 2016-01-06 | 南京大学 | 含哌嗪环的香豆素类衍生物及其制备与在抗菌药物中的应用 |
| US10702521B2 (en) | 2014-08-22 | 2020-07-07 | Glaxosmithkline Intellectual Property Development Limited | Methods for treating neisseria gonorrhoeae infection with substituted 1,2-dihydro-2A,5,8A-triazaacenaphthylene-3,8-diones |
| MA41168A (fr) * | 2014-12-17 | 2017-10-24 | Acraf | Nouveaux composés antibactériens |
| MA41169A (fr) * | 2014-12-17 | 2017-10-24 | Acraf | Composés antibactériens à large spectre d'activité |
| PL3468975T3 (pl) * | 2016-06-08 | 2020-09-07 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | Nowe związki przeciwbakteryjne |
-
2017
- 2017-06-05 PL PL17732775T patent/PL3468975T3/pl unknown
- 2017-06-05 EP EP17732775.6A patent/EP3468975B1/en active Active
- 2017-06-05 ES ES17732775T patent/ES2802233T3/es active Active
- 2017-06-05 SM SM20200335T patent/SMT202000335T1/it unknown
- 2017-06-05 DK DK17732775.6T patent/DK3468975T3/da active
- 2017-06-05 AU AU2017276627A patent/AU2017276627A1/en not_active Abandoned
- 2017-06-05 JP JP2018564236A patent/JP2019517545A/ja active Pending
- 2017-06-05 MX MX2018015126A patent/MX2018015126A/es unknown
- 2017-06-05 CN CN201780039687.1A patent/CN109415373A/zh active Pending
- 2017-06-05 SG SG11201810352XA patent/SG11201810352XA/en unknown
- 2017-06-05 WO PCT/EP2017/063601 patent/WO2017211760A1/en not_active Ceased
- 2017-06-05 CN CN201780042649.1A patent/CN109790157A/zh active Pending
- 2017-06-05 RS RS20200735A patent/RS60511B1/sr unknown
- 2017-06-05 LT LTEP17732775.6T patent/LT3468975T/lt unknown
- 2017-06-05 AU AU2017276626A patent/AU2017276626A1/en not_active Abandoned
- 2017-06-05 BR BR112018075334-3A patent/BR112018075334A2/pt not_active IP Right Cessation
- 2017-06-05 SG SG11201810389XA patent/SG11201810389XA/en unknown
- 2017-06-05 EA EA201892815A patent/EA201892815A1/ru unknown
- 2017-06-05 US US16/307,410 patent/US10633366B2/en not_active Expired - Fee Related
- 2017-06-05 EP EP17727595.5A patent/EP3468970A1/en not_active Withdrawn
- 2017-06-05 JP JP2018564240A patent/JP2019517546A/ja active Pending
- 2017-06-05 CA CA3025270A patent/CA3025270A1/en not_active Abandoned
- 2017-06-05 HU HUE17732775A patent/HUE049547T2/hu unknown
- 2017-06-05 KR KR1020187036946A patent/KR20190019084A/ko not_active Ceased
- 2017-06-05 PT PT177327756T patent/PT3468975T/pt unknown
- 2017-06-05 US US16/307,193 patent/US10640488B2/en not_active Expired - Fee Related
- 2017-06-05 MA MA045221A patent/MA45221A/fr unknown
- 2017-06-05 HR HRP20200894TT patent/HRP20200894T1/hr unknown
- 2017-06-05 CA CA3025624A patent/CA3025624A1/en not_active Abandoned
- 2017-06-05 ME MEP-2020-112A patent/ME03738B/me unknown
- 2017-06-05 MX MX2018015125A patent/MX2018015125A/es unknown
- 2017-06-05 MD MDE20190471T patent/MD3468975T2/ro not_active IP Right Cessation
- 2017-06-05 SI SI201730306T patent/SI3468975T1/sl unknown
- 2017-06-05 WO PCT/EP2017/063600 patent/WO2017211759A1/en not_active Ceased
- 2017-06-05 BR BR112018075297-5A patent/BR112018075297A2/pt not_active IP Right Cessation
- 2017-06-05 EA EA201892822A patent/EA201892822A1/ru unknown
- 2017-06-05 KR KR1020187036945A patent/KR20190019083A/ko not_active Ceased
- 2017-06-07 AR ARP170101554A patent/AR108777A1/es unknown
- 2017-06-07 AR ARP170101555A patent/AR108778A1/es unknown
-
2018
- 2018-11-26 IL IL263283A patent/IL263283A/en unknown
- 2018-11-26 IL IL263285A patent/IL263285A/en unknown
-
2020
- 2020-06-29 CY CY20201100597T patent/CY1123194T1/el unknown
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