[go: up one dir, main page]

LT3310345T - Burnoje disperguojama tabletė, turinti estetrolio - Google Patents

Burnoje disperguojama tabletė, turinti estetrolio

Info

Publication number
LT3310345T
LT3310345T LTEP16729601.1T LT16729601T LT3310345T LT 3310345 T LT3310345 T LT 3310345T LT 16729601 T LT16729601 T LT 16729601T LT 3310345 T LT3310345 T LT 3310345T
Authority
LT
Lithuania
Prior art keywords
tablet containing
dispersible tablet
oral dispersible
containing estetrol
estetrol
Prior art date
Application number
LTEP16729601.1T
Other languages
English (en)
Inventor
Séverine Francine Isabelle Jaspart
Johannes Jan Platteeuw
Denny Johan Marijn Van Den Heuvel
Original Assignee
Estetra Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Estetra Sprl filed Critical Estetra Sprl
Publication of LT3310345T publication Critical patent/LT3310345T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LTEP16729601.1T 2015-06-18 2016-06-17 Burnoje disperguojama tabletė, turinti estetrolio LT3310345T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15172751 2015-06-18
PCT/EP2016/064071 WO2016203009A1 (en) 2015-06-18 2016-06-17 Orodispersible tablet containing estetrol

Publications (1)

Publication Number Publication Date
LT3310345T true LT3310345T (lt) 2021-06-25

Family

ID=53476700

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP16729601.1T LT3310345T (lt) 2015-06-18 2016-06-17 Burnoje disperguojama tabletė, turinti estetrolio

Country Status (19)

Country Link
US (1) US10894014B2 (lt)
EP (1) EP3310345B1 (lt)
JP (1) JP6866561B2 (lt)
CN (1) CN107810001A (lt)
CA (1) CA2988485A1 (lt)
CY (1) CY1124104T1 (lt)
DK (1) DK3310345T3 (lt)
ES (1) ES2877186T3 (lt)
HR (1) HRP20210668T1 (lt)
HU (1) HUE054589T2 (lt)
LT (1) LT3310345T (lt)
MA (1) MA44205B1 (lt)
MD (1) MD3310345T2 (lt)
PL (1) PL3310345T3 (lt)
PT (1) PT3310345T (lt)
RS (1) RS61812B1 (lt)
SI (1) SI3310345T1 (lt)
SM (1) SMT202100370T1 (lt)
WO (1) WO2016203009A1 (lt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107266514A (zh) 2011-06-01 2017-10-20 埃斯特拉私人有限责任公司 用于产生雌四醇中间体的方法
BR112013030833B1 (pt) 2011-06-01 2019-09-03 Estetra S A processo para a preparação de um composto de fórmula (i) e processo para a preparação de estetrol
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
WO2016203009A1 (en) 2015-06-18 2016-12-22 Mithra Pharmaceuticals S.A. Orodispersible tablet containing estetrol
US20160367567A1 (en) 2015-06-18 2016-12-22 Mithra Pharmaceuticals S.A. Orodispersible dosage unit containing an estetrol component
EP3310346B1 (en) 2015-06-18 2021-03-24 Estetra SPRL Orodispersible tablet containing estetrol
PL3310333T3 (pl) 2015-06-18 2020-07-13 Estetra Sprl Ulegająca rozpadowi w jamie ustnej jednostka dawkowana zawierająca składnik estetrolowy
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
HU231240B1 (hu) 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
CN112770779B (zh) 2019-11-07 2022-07-22 旭化成株式会社 纤维素组合物、片剂及口腔崩解片
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物
JP2023543953A (ja) 2020-09-29 2023-10-18 ミリセント・ファーマ・リミテッド 口腔内分散性配合物

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3138588A (en) 1962-08-24 1964-06-23 American Home Prod 17-ketals of estrone and derivatives thereof
US3433785A (en) 1966-07-11 1969-03-18 Sterling Drug Inc 15,16-disubstituted aromatic steroids,intermediates and processes
US5073374A (en) 1988-11-30 1991-12-17 Schering Corporation Fast dissolving buccal tablet
US5340586A (en) 1991-04-12 1994-08-23 University Of Southern California Methods and formulations for use in treating oophorectomized women
JPH07101977A (ja) 1993-10-05 1995-04-18 Kureha Chem Ind Co Ltd ホルモン作用を軽減した新規なエストラジオール誘導体及びその増殖因子阻害剤
DE4344405C2 (de) 1993-12-24 1995-12-07 Marika Dr Med Ehrlich Ovulationshemmendes Mittel und Verfahren zur hormonalen Kontrazeption
WO1997004752A1 (en) 1995-07-26 1997-02-13 Duramed Pharmaceuticals, Inc. Pharmaceutical compositions of conjugated estrogens and methods for their use
US6117446A (en) 1999-01-26 2000-09-12 Place; Virgil A. Drug dosage unit for buccal administration of steroidal active agents
TW548277B (en) 1999-07-16 2003-08-21 Akzo Nobel Nv Orally active androgens
AU778017B2 (en) 1999-12-02 2004-11-11 N.V. Organon 14,15-beta-methylene substituted androgens
US20020132801A1 (en) 2001-01-11 2002-09-19 Schering Aktiengesellschaft Drospirenone for hormone replacement therapy
DE10044241A1 (de) * 2000-09-07 2002-03-21 Mahle Gmbh Kolbenring für Kolben-Maschine
EP1216713A1 (en) 2000-12-20 2002-06-26 Schering Aktiengesellschaft Compositions of estrogen-cyclodextrin complexes
EP1260225A1 (en) 2001-05-18 2002-11-27 Pantarhei Bioscience B.V. A pharmaceutical composition for use in hormone replacement therapy
WO2002094276A1 (en) 2001-05-18 2002-11-28 Pantarhei Bioscience B.V. Pharmaceutical composition for use in hormone replacement therapy
ES2296943T3 (es) 2001-05-23 2008-05-01 Pantarhei Bioscience B.V. Sistema de administracion de un medicamento estrogeno tetrahidroxilado destinado a la contracepcion hormonal.
EP1390041B1 (en) 2001-05-23 2009-11-25 Pantarhei Bioscience B.V. Drug delivery system comprising a tetrahydroxylated estrogen for use in hormonal contraception
WO2003018026A1 (en) 2001-08-31 2003-03-06 Pantarhei Bioscience B.V. Use of estrogenic compounds in combination with progestogenic compounds in hormone-replacement therapy
ES2278925T3 (es) 2001-11-15 2007-08-16 Pantarhei Bioscience B.V. Uso de compuestos estrogenicos en combinacion con compuestos progestogenicos en terapias de sustitucion hormonal.
US6723348B2 (en) 2001-11-16 2004-04-20 Ethypharm Orodispersible tablets containing fexofenadine
HU227198B1 (en) 2001-11-27 2010-10-28 Richter Gedeon Nyrt Pharmaceutical composition for emergency contraception containing levonorgestrel
EP1478373B1 (en) 2002-02-21 2006-10-04 Schering Aktiengesellschaft Pharmaceutical compositions comprising one or more steroids one or more tetrahydrofolate components and vitamin b12
US20050147670A1 (en) 2002-05-29 2005-07-07 Impax Laboratories Inc. Oral disintegrating dosage forms
WO2003103685A1 (en) 2002-06-11 2003-12-18 Pantarhei Bioscience B.V. A method of treating human skin and a skin care composition for use in such a method
SI1511496T1 (sl) 2002-06-11 2007-04-30 Pantarhei Bioscience Bv Metoda zdravljenja ali prevencije imunsko mediiranih motenj in farmacevtska formulacija za njeno uporabo
CA2492287C (en) * 2002-07-12 2011-12-13 Pantarhei Bioscience B.V. Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy
WO2004019954A1 (en) 2002-08-28 2004-03-11 Robert Casper Estrogen replacement regimen
SI1556058T1 (sl) 2002-10-23 2008-02-29 Pantarhei Bioscience Bv Farmacevtski sestavki, ki obsegajo estetrolne derivate, za uporabo pri zdravljenju raka
ATE454155T1 (de) 2002-11-05 2010-01-15 Bayer Schering Pharma Ag Verwendung von drospirenon zur behandlung von hypertension
CA2505190C (en) 2002-11-08 2012-07-10 Pantarhei Bioscience B.V. Synthesis of estetrol via estrone derived steroids
CN100431545C (zh) * 2003-05-22 2008-11-12 潘塔希生物科学股份有限公司 雌激素成分在制备用于治疗及预防肌与骨疼痛中的组合物中的应用
AU2004275469B2 (en) 2003-09-29 2010-07-15 Novo Nordisk Health Care Ag HRT formulations
EP1673071A1 (en) 2003-09-29 2006-06-28 Novo Nordisk Femcare AG Improved stability of progestogen formulations
EP1535618A1 (en) 2003-11-26 2005-06-01 Schering Aktiengesellschaft Pharmaceutical preparation for continuous hormonal treatment over a period of longer than 21-28 days comprising two estrogen and/or progestin compositions
MY151322A (en) 2004-04-30 2014-05-15 Bayer Ip Gmbh Management of breakthrough bleeding in extended hormonal contraceptive regimens
GB0410616D0 (en) 2004-05-13 2004-06-16 Unilever Plc Antiperspirant or deodorant compositions
DE102004026670A1 (de) 2004-05-28 2005-12-15 Grünenthal GmbH Hormonales Kontrazeptivum enthaltend eine Kombination aus Ethinylestradiol und Chlormadinonacetat
SI1755562T1 (sl) 2004-05-28 2014-02-28 Richter Gedeon Nyrt. Kontracepcijsko sredstvo, ki vsebuje folno kislino
UA89964C2 (ru) 2004-09-08 2010-03-25 Н.В. Органон 15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ
UY29527A1 (es) 2005-05-13 2006-12-29 Schering Ag Composicinn farmaccutica que contienen gestrgenos y/o estrngenos y 5-metil - (6s) - tetrhidrofolato.
AU2006251154B2 (en) 2005-05-26 2012-06-28 Solvay Pharmaceuticals Gmbh 17beta-HSD1 and STS inhibitors
US20070048369A1 (en) 2005-08-26 2007-03-01 National Starch And Chemical Investment Holding Corporation Mucosal delivery tablet
EP1971344B1 (en) 2006-01-09 2010-09-22 Pantarhei Bioscience B.V. A method of treating an acute vascular disorder
EP1993531B1 (en) 2006-03-02 2015-10-14 Warner Chilcott Company, LLC Extended cycle multiphasic oral contraceptive method
CA2649361C (en) 2006-06-08 2014-09-30 Warner Chilcott Company, Inc. Methods to administer solid dosage forms of ethinyl estradiol and prodrugs thereof with improved bioavailability
US20070286819A1 (en) 2006-06-08 2007-12-13 Warner Chilcott Company, Inc. Methods to administer ethinyl estradiol and prodrugs thereof with improved bioavailability
US20080113953A1 (en) 2006-06-08 2008-05-15 Warner Chilcott Company, Inc. Methods to administer solid dosage forms of ethinyl estradiol and prodrugs thereof with improved bioavailability
JP2009542588A (ja) 2006-07-06 2009-12-03 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト 避妊及び先天的異常の危険性の予防のための医薬製剤
CN101489563A (zh) 2006-07-06 2009-07-22 拜耳先灵医药股份有限公司 用于避孕和预防先天性畸形风险的药物制剂
BRPI0719675A2 (pt) 2006-11-29 2013-12-24 Wyeth Corp Comprimido com bicamada de estrogênio/serm e estrogênio/progestina
BRPI0719486A2 (pt) 2006-12-20 2014-02-18 Duramed Pharmaceuticals Inc "forma farmacêutica sólida oral desitegrante, não-efervescente, métodos para tratar uma mulher que necessite de um contraceptivo de emergência, pacote terapêutico para tratar uma mulher que necessite de contracepção de emergência e processo para a preparação de uma forma sólida de dosagem farmacêutica oral desintegrante, não-efervescente"
DE602008001783D1 (de) 2007-01-08 2010-08-26 Pantarhei Bioscience Bv Verfahren zur behandlung oder prävention von unfruchtbarkeit bei weiblichen säugern und pharmazeutisches kit zur anwendung dieses verfahrens
WO2008089087A2 (en) 2007-01-12 2008-07-24 Wyeth Tablet-in-tablet compositions
EP2155205B1 (en) 2007-06-21 2011-12-21 Pantarhei Bioscience B.V. Treatment of meconium aspiration syndrome with estrogens
WO2009011576A1 (en) * 2007-07-19 2009-01-22 Pantarhei Bioscience B.V. Treatment or prevention of hypertensive disorders of pregnancy or fetal growth retardation
US20110250274A1 (en) * 2008-09-19 2011-10-13 Shaked Ze Ev Estriol formulations
CN101780073B (zh) * 2009-01-21 2013-07-03 重庆圣华曦药业股份有限公司 非布司他分散片药物及其制备方法
DE102009007771B4 (de) 2009-02-05 2012-02-16 Bayer Schering Pharma Aktiengesellschaft Bukkales Applikationssystem, 17α-Estradiol enthaltend
EP3178476A1 (de) 2009-06-23 2017-06-14 Bayer Intellectual Property GmbH Pharmazeutische zusammensetzung und behandlungsverfahren zur notfallempfängnisverhütung
CN102058604A (zh) 2009-11-17 2011-05-18 北京万全阳光医学技术有限公司 一种含有地诺孕素和戊酸雌二醇的药物组合物及其制备方法
CN102985070A (zh) 2010-04-15 2013-03-20 拜耳知识产权有限责任公司 用于hrt的极低剂量的固体口服剂型
US10849857B2 (en) 2010-07-28 2020-12-01 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
AR081670A1 (es) 2010-06-29 2012-10-10 Leon Farma Sa Lab Composicion farmaceutica que comprende drospirenona y kit anticonceptivo
US9603860B2 (en) 2010-07-28 2017-03-28 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
WO2012055840A1 (en) 2010-10-28 2012-05-03 Bayer Pharma Aktiengesellschaft Composition and preparation for treatment of dysmenorrhea and menstrual pain and use of a hormonal agent and a zinc salt for treatment of menstrual disorders
CN107266514A (zh) 2011-06-01 2017-10-20 埃斯特拉私人有限责任公司 用于产生雌四醇中间体的方法
BR112013030833B1 (pt) 2011-06-01 2019-09-03 Estetra S A processo para a preparação de um composto de fórmula (i) e processo para a preparação de estetrol
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
ES2545337T3 (es) 2011-07-19 2015-09-10 Pantarhei Bioscience B.V. Comprimido que contiene dehidroepiandrosterona (DHEA)
HUE033590T2 (hu) 2011-08-11 2017-12-28 Estetra Sprl Esztetrol alkalmazása sürgõsségi fogamzásgátlóként
CA2848785A1 (en) 2011-09-16 2013-03-21 Ferring B.V. A fast dissolving pharmaceutical composition
PT2764008T (pt) 2011-10-07 2016-11-10 Estetra Sprl Processo para a produção de estetrol
EP2790688B1 (en) 2011-12-13 2019-11-20 Arstat, Inc. A multiphasic contraceptive regimen for an oral formulation of progestin and estrogen
EP2653163A1 (en) * 2012-04-19 2013-10-23 Université de Liège Estrogenic components for use in the treatment of neurological disorders
US9808470B2 (en) 2012-04-19 2017-11-07 Universite De Liege Estrogenic components for use in the treatment of neurological disorders
US9238265B2 (en) * 2012-09-27 2016-01-19 General Electric Company Backstrike protection during machining of cooling features
WO2014159377A1 (en) 2013-03-14 2014-10-02 Teva Women's Health, Inc. Compositions containing tanaproget and natural estrogens
EP2999474A4 (en) 2013-05-21 2016-12-28 Predictive Therapeutics Llc THERAPEUTIC AND METHOD FOR USE
WO2015040051A1 (en) 2013-09-18 2015-03-26 Crystal Pharma, S.A.U. Process for the preparation of estetrol
EP3076944A1 (fr) * 2013-12-04 2016-10-12 Galderma Research & Development Microcapsules lipidiques comprenant de preference un actif lipophile et composition les contenant, leur procede de preparation et leur utilisation en dermatologie et en cosmetique
MA39105B1 (fr) 2013-12-12 2018-05-31 Donesta Bioscience B V Unité de dosage solide se désintégrant par voie orale contenant un constituant estétrol
US9962395B2 (en) 2014-09-29 2018-05-08 The Regents Of The University Of California Compositions and methods for maintaining cognitive function
BR112017024783A2 (pt) 2015-05-18 2018-08-07 Agile Therapeutics Inc composições contraceptivas e métodos para eficácia melhorada e modulação dos efeitos colaterais
WO2016203009A1 (en) 2015-06-18 2016-12-22 Mithra Pharmaceuticals S.A. Orodispersible tablet containing estetrol
PL3310333T3 (pl) * 2015-06-18 2020-07-13 Estetra Sprl Ulegająca rozpadowi w jamie ustnej jednostka dawkowana zawierająca składnik estetrolowy
EP3310346B1 (en) 2015-06-18 2021-03-24 Estetra SPRL Orodispersible tablet containing estetrol
US20160367567A1 (en) * 2015-06-18 2016-12-22 Mithra Pharmaceuticals S.A. Orodispersible dosage unit containing an estetrol component
JP6827962B2 (ja) 2015-06-23 2021-02-10 ラボラトリオス レオン ファーマ エスエー 過剰体重に影響される女性患者のためのドロスピレノン系避妊薬
JP2018533542A (ja) 2016-10-28 2018-11-15 エステトラ ソシエテ プリーヴ ア レスポンサビリテ リミテ 月経困難症および月経痛の管理のための方法
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
US20200046729A1 (en) 2016-08-05 2020-02-13 Estetra Sprl Methods using combined oral contraceptive compositions with reduced cardiovascular effects
JP2021513507A (ja) 2018-02-07 2021-05-27 エステトラ ソシエテ プリーヴ ア レスポンサビリテ リミテ 心臓血管系への影響を低減した避妊薬組成物

Also Published As

Publication number Publication date
JP6866561B2 (ja) 2021-04-28
ES2877186T3 (es) 2021-11-16
WO2016203009A1 (en) 2016-12-22
JP2018517718A (ja) 2018-07-05
US20180185271A1 (en) 2018-07-05
EP3310345A1 (en) 2018-04-25
MD3310345T2 (ro) 2021-07-31
US10894014B2 (en) 2021-01-19
PT3310345T (pt) 2021-05-28
RS61812B1 (sr) 2021-06-30
CY1124104T1 (el) 2022-05-27
EP3310345B1 (en) 2021-03-31
SMT202100370T1 (it) 2021-07-12
DK3310345T3 (da) 2021-05-25
SI3310345T1 (sl) 2021-05-31
PL3310345T3 (pl) 2021-10-18
CN107810001A (zh) 2018-03-16
HRP20210668T1 (hr) 2021-05-28
MA44205B1 (fr) 2021-04-30
CA2988485A1 (en) 2016-12-22
HUE054589T2 (hu) 2021-09-28
MA44205A (fr) 2018-04-25

Similar Documents

Publication Publication Date Title
LT3310345T (lt) Burnoje disperguojama tabletė, turinti estetrolio
EP3490539A4 (en) NEW ORAL FORMULATION.
LT3701944T (lt) Burnoje disperguojamas dozavimo vienetas, kurio sudėtyje yra estetrolio komponentas
HUE054551T2 (hu) Ösztetrolt tartalmazó, szájban diszpergálódó tabletta
IL253840A0 (en) Oral treatment system
DK3265421T3 (da) Doseringssystem
BR112016023628A2 (pt) composições farmacêuticas.
EP3297586C0 (en) ORAL APPLIANCE
HUE054344T2 (hu) Gyógyászati készítmények AZD9291 tartalommal
SI4070787T1 (sl) Farmacevtske formulacije
DK3283058T3 (da) Ribociclib-tablet
DK3229816T3 (en) Proton-bindende polymerer til oral administration
SG11201707719WA (en) Dispersible dosage form
KR20180084810A (ko) 정제 세트
DK3280447T3 (da) Farmaceutiske formuleringer
DK3383397T3 (da) Farmaceutiske sammensætninger indeholdende doravirin, tenofovirdisoproxilfumarat og lamivudin
ITUB20153699A1 (it) Integratore orale
GB201517133D0 (en) New pharmaceutical use
EP3167870C0 (en) TAMPER-PROOF ORAL DOSAGE FORM
BR112017018293A2 (pt) brocas dentárias.
BR112016028542A2 (pt) implemento de cuidado oral.
BR112017004882A2 (pt) composição farmacêutica oral.
GB2522237B (en) Oral fragrance device
TH1501006970A (th) ยาเม็ดชนิดแตกตัวได้ในช่องปาก
GB201517454D0 (en) New pharmaceutical use