LT3140318T - Kv1.3 kalio kanalų antagonistai - Google Patents

Kv1.3 kalio kanalų antagonistai

Info

Publication number: LT3140318T
Authority: LT; Lithuania
Prior art keywords: potassive; channel antagonists; antagonists; channel; potassive channel
Prior art date: 2014-05-08

Application number

LTEP15721694.6T

Other languages

English (en)

Inventor

Andreas Klostermann

Jörg STOCKHAUS

Original Assignee

SelectION Therapeutics GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-05-08

Filing date

2015-05-07

Publication date

2020-01-10

2015-05-07 Application filed by SelectION Therapeutics GmbH filed Critical SelectION Therapeutics GmbH

2020-01-10 Publication of LT3140318T publication Critical patent/LT3140318T/lt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
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- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Toxicology (AREA)
Diabetes (AREA)
Cell Biology (AREA)
Hematology (AREA)
Endocrinology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Obesity (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Marine Sciences & Fisheries (AREA)
Reproductive Health (AREA)
Emergency Medicine (AREA)
Transplantation (AREA)
Child & Adolescent Psychology (AREA)

LTEP15721694.6T 2014-05-08 2015-05-07 Kv1.3 kalio kanalų antagonistai LT3140318T (lt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB1408135.0A GB201408135D0 (en)	2014-05-08	2014-05-08	Kv1.3 potassium channel antagonists
PCT/EP2015/060073 WO2015169901A1 (en)	2014-05-08	2015-05-07	Kv1.3 potassium channel antagonists

Publications (1)

Publication Number	Publication Date
LT3140318T true LT3140318T (lt)	2020-01-10

Family

ID=51032421

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LTEP15721694.6T LT3140318T (lt)	2014-05-08	2015-05-07	Kv1.3 kalio kanalų antagonistai

Country Status (21)

Country	Link
US (2)	US10370413B2 (lt)
EP (2)	EP3140318B1 (lt)
JP (1)	JP6989377B2 (lt)
KR (1)	KR102449653B1 (lt)
CN (2)	CN106661093B (lt)
AU (2)	AU2015257694B2 (lt)
CA (1)	CA2954076C (lt)
CY (1)	CY1122445T1 (lt)
DK (1)	DK3140318T3 (lt)
ES (1)	ES2763315T3 (lt)
GB (1)	GB201408135D0 (lt)
HR (1)	HRP20192307T1 (lt)
HU (1)	HUE046915T2 (lt)
IL (1)	IL248807B (lt)
LT (1)	LT3140318T (lt)
PL (1)	PL3140318T3 (lt)
PT (1)	PT3140318T (lt)
RS (1)	RS59676B1 (lt)
SI (1)	SI3140318T1 (lt)
SM (1)	SMT201900742T1 (lt)
WO (1)	WO2015169901A1 (lt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN110540585B (zh) *	2019-09-03	2022-07-01	昆明医科大学	一种具有改善脑缺血缺氧的蝎子毒素活性多肽HsTx1及其制备方法与应用
US20240417433A1 (en) *	2021-10-15	2024-12-19	Nantong Yichen Biopharma. Co. Ltd.	Bispecific Binding Molecule
WO2025133134A1 (en)	2023-12-21	2025-06-26	SelectION Therapeutics GmbH	Peptide for treating atopic dermatitis
WO2025133137A1 (en)	2023-12-21	2025-06-26	SelectION Therapeutics GmbH	Peptide for treating psoriasis vulgaris or psoriatic arthritis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5185433A (en) *	1990-04-09	1993-02-09	Centocor, Inc.	Cross-linking protein compositions having two or more identical binding sites
US20090175821A1 (en) *	1999-05-17	2009-07-09	Bridon Dominique P	Modified therapeutic peptides with extended half-lives in vivo
WO2006042151A2 (en) *	2004-10-07	2006-04-20	The Regents Of The University Of California	Analogs of shk toxin and their uses in selective inhibition of kv1.3 potassium channels
US7833979B2 (en) *	2005-04-22	2010-11-16	Amgen Inc.	Toxin peptide therapeutic agents
EP2081602A2 (en) *	2006-10-25	2009-07-29	Amgen Inc.	Toxin peptide therapeutic agents
CA2681974C (en)	2007-03-29	2019-12-31	Genmab A/S	Bispecific antibodies and methods for production thereof
ATE537185T1 (de) *	2007-05-14	2011-12-15	Univ Mexico Nacional Autonoma	Vm23 und vm24, zwei skorpionpeptide, die humane t-lymphozyten-kaliumkanäle (untertyp kv1.3) mit hoher selektivität blockieren
WO2018013483A1 (en) *	2016-07-11	2018-01-18	The California Institute For Biomedical Research	Kv1.3 channel blocking peptides and uses thereof

2014
- 2014-05-08 GB GBGB1408135.0A patent/GB201408135D0/en not_active Ceased
2015
- 2015-05-07 DK DK15721694.6T patent/DK3140318T3/da active
- 2015-05-07 SI SI201531046T patent/SI3140318T1/sl unknown
- 2015-05-07 HU HUE15721694A patent/HUE046915T2/hu unknown
- 2015-05-07 HR HRP20192307TT patent/HRP20192307T1/hr unknown
- 2015-05-07 US US15/309,781 patent/US10370413B2/en active Active
- 2015-05-07 SM SM20190742T patent/SMT201900742T1/it unknown
- 2015-05-07 CN CN201580036572.8A patent/CN106661093B/zh active Active
- 2015-05-07 WO PCT/EP2015/060073 patent/WO2015169901A1/en not_active Ceased
- 2015-05-07 PL PL15721694T patent/PL3140318T3/pl unknown
- 2015-05-07 CN CN202110360331.6A patent/CN113150078A/zh active Pending
- 2015-05-07 EP EP15721694.6A patent/EP3140318B1/en active Active
- 2015-05-07 ES ES15721694T patent/ES2763315T3/es active Active
- 2015-05-07 AU AU2015257694A patent/AU2015257694B2/en active Active
- 2015-05-07 EP EP19205791.7A patent/EP3660038A1/en not_active Withdrawn
- 2015-05-07 JP JP2017510759A patent/JP6989377B2/ja active Active
- 2015-05-07 RS RS20191608A patent/RS59676B1/sr unknown
- 2015-05-07 KR KR1020167034434A patent/KR102449653B1/ko active Active
- 2015-05-07 PT PT157216946T patent/PT3140318T/pt unknown
- 2015-05-07 LT LTEP15721694.6T patent/LT3140318T/lt unknown
- 2015-05-07 CA CA2954076A patent/CA2954076C/en active Active
2016
- 2016-11-07 IL IL248807A patent/IL248807B/en active IP Right Grant
2019
- 2019-02-21 US US16/281,861 patent/US10800815B2/en active Active
- 2019-10-04 AU AU2019240693A patent/AU2019240693B2/en active Active
- 2019-12-23 CY CY20191101351T patent/CY1122445T1/el unknown

Also Published As

Publication number	Publication date
US20190375795A1 (en)	2019-12-12
AU2015257694A1 (en)	2017-01-05
CA2954076C (en)	2023-07-11
US20170137470A1 (en)	2017-05-18
CY1122445T1 (el)	2021-01-27
IL248807A0 (en)	2017-01-31
AU2019240693A1 (en)	2019-10-24
SMT201900742T1 (it)	2020-03-13
AU2015257694B2 (en)	2019-07-04
CA2954076A1 (en)	2015-11-12
US10370413B2 (en)	2019-08-06
AU2019240693B2 (en)	2020-10-15
CN106661093A (zh)	2017-05-10
GB201408135D0 (en)	2014-06-25
KR20170013898A (ko)	2017-02-07
US10800815B2 (en)	2020-10-13
EP3660038A1 (en)	2020-06-03
EP3140318B1 (en)	2019-10-30
WO2015169901A1 (en)	2015-11-12
ES2763315T3 (es)	2020-05-28
IL248807B (en)	2020-03-31
KR102449653B1 (ko)	2022-09-29
SI3140318T1 (sl)	2020-02-28
EP3140318A1 (en)	2017-03-15
HUE046915T2 (hu)	2020-04-28
HRP20192307T1 (hr)	2020-03-20
JP2017515502A (ja)	2017-06-15
JP6989377B2 (ja)	2022-01-05
RS59676B1 (sr)	2020-01-31
CN113150078A (zh)	2021-07-23
PT3140318T (pt)	2020-01-07
CN106661093B (zh)	2021-04-20
PL3140318T3 (pl)	2020-05-18
DK3140318T3 (da)	2020-01-02

Publication	Publication Date	Title
LT3230281T (lt)	2021-07-12	1,3-tiazol-2-ilu pakeisti benzamidai
EP3452423A4 (en)	2019-11-20	SYNTHETIC PUZZANANE
CL2015000278S1 (es)	2015-06-05	Tapa.
BR112017004332A2 (pt)	2018-08-07	perfis.
DK3175063T3 (da)	2020-01-06	Et forbedret hængsel.
DK3143037T3 (da)	2021-09-20	Alpha4beta7-integrin-thioether-peptidantagonister
EP3713931C0 (en)	2025-03-05	3-OXO-6-HETEROARYL-2-PHENYL-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDE
BR112017001387A2 (pt)	2018-06-05	alargador.
KR20180084876A (ko)	2018-07-25	내플라즈마성 부재
CL2014002537S1 (es)	2015-01-16	Tapa.
FR3023988B3 (fr)	2016-07-22	.
BR112017001389A2 (pt)	2018-06-05	alargador.
CL2014002710S1 (es)	2015-05-04	Dispositivo nebulizador.
BR112017001388A2 (pt)	2018-06-05	alargador.
BR112017001386A2 (pt)	2018-06-05	alargador.
DK3325745T3 (da)	2019-09-30	Skydedørsanordning
IT201600084952A1 (it)	2018-02-12	Coglifrutta.
ES1150114Y (es)	2016-04-25	Abarcón.
CL2014002709S1 (es)	2015-05-04	Dispositivo nebulizador.
IL248807A0 (en)	2017-01-31	Kv1.3 potassium channel antagonists
DK3310756T3 (da)	2021-03-08	Thromboxanreceptorantagonister
DK3237407T3 (da)	2020-07-20	3,5-diaminopyrazolkinasehæmmere
FR3045065B1 (fr)	2018-01-19	Peinture bi-composant anti-amiante.
IT201600131035A1 (it)	2018-06-27	Dispositivo pulisci-vetro.
IT201600132795A1 (it)	2018-06-30	Capsulismo.