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LT2984108T - Anti-s100a7 antikūnai, skirti vėžio gydymui ir diagnozei - Google Patents

Anti-s100a7 antikūnai, skirti vėžio gydymui ir diagnozei

Info

Publication number
LT2984108T
LT2984108T LTEP14723729.1T LT14723729T LT2984108T LT 2984108 T LT2984108 T LT 2984108T LT 14723729 T LT14723729 T LT 14723729T LT 2984108 T LT2984108 T LT 2984108T
Authority
LT
Lithuania
Prior art keywords
antibodies
diagnosis
cancer
treatment
Prior art date
Application number
LTEP14723729.1T
Other languages
English (en)
Inventor
José Luis HERNANDEZ MIGUEZ
Jaume Adan Plana
Josep Maria MARTINEZ ESCOLA
Marc Masa Alvarez
Ramon Messeguer Peypoch
Francesc Mitjans Prat
Sheila Dakhel Plaza
Antonio Coll Manzano
Rosa M HERVAS VILLEGAS
Carme Calvis Calpe
Laura Padilla Garcia
Lourdes Tatiana Roque Navarro
Laura Barbera Ferrando
Manuel Rivas Canas
Original Assignee
Lykera Biomed, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lykera Biomed, S.A. filed Critical Lykera Biomed, S.A.
Publication of LT2984108T publication Critical patent/LT2984108T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6843Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015Breast
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046Stomach, Intestines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3053Skin, nerves, brain
    • G01N33/57515
    • G01N33/57535
    • G01N33/57557
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4727Calcium binding proteins, e.g. calmodulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
LTEP14723729.1T 2013-04-09 2014-04-09 Anti-s100a7 antikūnai, skirti vėžio gydymui ir diagnozei LT2984108T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13382128 2013-04-09
PCT/EP2014/057213 WO2014167030A1 (en) 2013-04-09 2014-04-09 Anti-s100a7 antibodies for the treatment and diagnosis of cancer

Publications (1)

Publication Number Publication Date
LT2984108T true LT2984108T (lt) 2017-11-10

Family

ID=48049929

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP14723729.1T LT2984108T (lt) 2013-04-09 2014-04-09 Anti-s100a7 antikūnai, skirti vėžio gydymui ir diagnozei

Country Status (11)

Country Link
US (1) US9914768B2 (lt)
EP (1) EP2984108B1 (lt)
CN (1) CN105873950A (lt)
CY (1) CY1119430T1 (lt)
DK (1) DK2984108T3 (lt)
ES (1) ES2639227T3 (lt)
LT (1) LT2984108T (lt)
PL (1) PL2984108T3 (lt)
PT (1) PT2984108T (lt)
SM (1) SMT201700402T1 (lt)
WO (1) WO2014167030A1 (lt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2784946T3 (es) * 2016-03-14 2020-10-02 Somalogic Inc Compuestos y métodos para la síntesis de 5-(triptaminocarboxiamida n-protegida)-2'-desoxiuridina fosforamidita para su incorporación a una secuencia de ácido nucleico
KR102645432B1 (ko) * 2016-03-28 2024-03-11 (주)아모레퍼시픽 피부 세포 분화 촉진용 조성물 및 피부 세포 분화 촉진 물질의 스크리닝 방법
CN106943594A (zh) * 2017-03-29 2017-07-14 西安交通大学 Psoriasin抗体和LL‑37抗体在制备防治银屑病的药物中的应用
WO2024119068A2 (en) * 2022-12-02 2024-06-06 Ohio State Innovation Foundation S100a7 as a diagnostic marker and therapeutic target for disorders
EP4672980A2 (en) * 2023-03-01 2026-01-07 Bountica Ltd. An eco-friendly, sustainable food preservative
CN119638830B (zh) * 2024-12-24 2025-11-14 武汉爱博泰克生物科技有限公司 针对人s100a7蛋白的抗体、抗体对和试剂盒及其用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4263428A (en) 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
ATE12348T1 (de) 1980-11-10 1985-04-15 Gersonde Klaus Prof Dr Verfahren zur herstellung von lipid-vesikeln durch ultraschallbehandlung, anwendung des verfahrens und vorrichtung zur durchfuehrung des verfahrens.
EP0088046B1 (de) 1982-02-17 1987-12-09 Ciba-Geigy Ag Lipide in wässriger Phase
EP0143949B1 (en) 1983-11-01 1988-10-12 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Pharmaceutical composition containing urokinase
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
IE922437A1 (en) 1991-07-25 1993-01-27 Idec Pharma Corp Recombinant antibodies for human therapy
WO1993011161A1 (en) 1991-11-25 1993-06-10 Enzon, Inc. Multivalent antigen-binding proteins
US6113898A (en) 1995-06-07 2000-09-05 Idec Pharmaceuticals Corporation Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies
ES2338774T3 (es) * 2001-12-31 2010-05-12 Dana-Farber Cancer Institute, Inc. Expresion de psoriasina por las celulas epiteliales mamarias.
US20100021472A1 (en) 2008-07-25 2010-01-28 Geetha Srikrishna Methods for diagnosing and treating cancer
MX347734B (es) 2010-06-14 2017-05-11 Lykera Biomed Sa Anticuerpos anti-s100a4 y usos aplicaciones terapéuticas.

Also Published As

Publication number Publication date
EP2984108A1 (en) 2016-02-17
CN105873950A (zh) 2016-08-17
WO2014167030A1 (en) 2014-10-16
PL2984108T3 (pl) 2017-12-29
DK2984108T3 (en) 2017-09-18
PT2984108T (pt) 2017-09-19
CY1119430T1 (el) 2018-03-07
SMT201700402T1 (it) 2017-11-15
US9914768B2 (en) 2018-03-13
US20160289307A1 (en) 2016-10-06
EP2984108B1 (en) 2017-05-31
ES2639227T3 (es) 2017-10-25

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