LT2890699T - Kristalinės 1-(5'-(5-(3,5-dichlor-4-fluorfenil)-5-(trifluormetil)-4,5-dihidroizoksazol-3-il)-3'h-spiro[azetidin-3,1'-izobenzofuran]-1-il)-2-(metilsulfonil)etano formos - Google Patents
Kristalinės 1-(5'-(5-(3,5-dichlor-4-fluorfenil)-5-(trifluormetil)-4,5-dihidroizoksazol-3-il)-3'h-spiro[azetidin-3,1'-izobenzofuran]-1-il)-2-(metilsulfonil)etano formosInfo
- Publication number
- LT2890699T LT2890699T LTEP13756985.1T LT13756985T LT2890699T LT 2890699 T LT2890699 T LT 2890699T LT 13756985 T LT13756985 T LT 13756985T LT 2890699 T LT2890699 T LT 2890699T
- Authority
- LT
- Lithuania
- Prior art keywords
- dihydroisoxazol
- isobenzofuran
- azetidine
- ethanone
- methylsulfonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261695410P | 2012-08-31 | 2012-08-31 | |
| PCT/US2013/056945 WO2014036056A1 (en) | 2012-08-31 | 2013-08-28 | Crystalline forms of 1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'h-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT2890699T true LT2890699T (lt) | 2018-06-25 |
Family
ID=49115603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP13756985.1T LT2890699T (lt) | 2012-08-31 | 2013-08-28 | Kristalinės 1-(5'-(5-(3,5-dichlor-4-fluorfenil)-5-(trifluormetil)-4,5-dihidroizoksazol-3-il)-3'h-spiro[azetidin-3,1'-izobenzofuran]-1-il)-2-(metilsulfonil)etano formos |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US9200003B2 (lt) |
| EP (1) | EP2890699B1 (lt) |
| JP (1) | JP6109942B2 (lt) |
| KR (1) | KR101736643B1 (lt) |
| CN (1) | CN104812758B (lt) |
| AR (1) | AR092409A1 (lt) |
| AU (1) | AU2013308887B2 (lt) |
| BR (1) | BR112015004135B8 (lt) |
| CA (1) | CA2881467C (lt) |
| CL (1) | CL2015000332A1 (lt) |
| CY (1) | CY1120611T1 (lt) |
| DK (1) | DK2890699T3 (lt) |
| ES (1) | ES2671271T3 (lt) |
| HR (1) | HRP20180861T1 (lt) |
| HU (1) | HUE037667T2 (lt) |
| LT (1) | LT2890699T (lt) |
| MX (1) | MX351463B (lt) |
| NO (1) | NO2931268T3 (lt) |
| NZ (1) | NZ704175A (lt) |
| PH (1) | PH12015500441A1 (lt) |
| PL (1) | PL2890699T3 (lt) |
| PT (1) | PT2890699T (lt) |
| RS (1) | RS57284B1 (lt) |
| RU (1) | RU2614978C2 (lt) |
| SI (1) | SI2890699T1 (lt) |
| TR (1) | TR201807735T4 (lt) |
| WO (1) | WO2014036056A1 (lt) |
| ZA (1) | ZA201500728B (lt) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2748631T3 (es) * | 2012-09-07 | 2020-03-17 | Zoetis Services Llc | Combinaciones parasiticidas de isoxazolina espirocíclica |
| HK1210472A1 (en) * | 2012-09-07 | 2016-04-22 | Zoetis Services Llc | Spirocyclic derivatives as antiparasitic agents |
| US20160081986A1 (en) * | 2013-05-20 | 2016-03-24 | Zoetis Services Llc | Long-acting spiro-isoxazoline antiparasitic compositions |
| WO2016022066A1 (en) | 2014-08-04 | 2016-02-11 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| EP3204390B1 (en) | 2014-10-06 | 2019-06-05 | Basf Se | Substituted pyrimidinium compounds for combating animal pests |
| BR112017009513A2 (pt) | 2014-11-06 | 2018-02-06 | Basf Se | utilização de um composto heterobicíclico, utilização dos compostos i, compostos, composição agrícola ou veterinária, método para o combate ou controle de pragas, método para a proteção de culturas e sementes |
| WO2016162371A1 (en) | 2015-04-07 | 2016-10-13 | Basf Agrochemical Products B.V. | Use of an insecticidal carboxamide compound against pests on cultivated plants |
| WO2016198611A1 (en) | 2015-06-11 | 2016-12-15 | Basf Se | N-(thio)acylimino heterocyclic compounds |
| WO2016198613A1 (en) | 2015-06-11 | 2016-12-15 | Basf Se | N-(thio)acylimino compounds |
| WO2017016883A1 (en) | 2015-07-24 | 2017-02-02 | Basf Se | Process for preparation of cyclopentene compounds |
| US11142514B2 (en) | 2015-10-02 | 2021-10-12 | Basf Se | Imino compounds with a 2-chloropyrimidin-5-yl substituent as pest-control agents |
| CN113303339A (zh) | 2015-11-30 | 2021-08-27 | 巴斯夫欧洲公司 | 顺式-茉莉酮和解淀粉芽孢杆菌的混合物 |
| BR112018068034A2 (pt) | 2016-03-09 | 2019-01-08 | Basf Se | compostos espiro da fórmula i, composição, composição agrícola para combater pragas animais, método de combate ou controle de pragas invertebradas, método de proteção de plantas, semente e uso dos compostos |
| WO2017153218A1 (en) | 2016-03-11 | 2017-09-14 | Basf Se | Method for controlling pests of plants |
| PE20181898A1 (es) | 2016-04-01 | 2018-12-11 | Basf Se | Compuestos biciclicos |
| WO2018082962A1 (en) * | 2016-11-02 | 2018-05-11 | Basf Se | Process for preparation of tetrahydrothiophene derivatives |
| KR20190092539A (ko) | 2016-12-16 | 2019-08-07 | 바스프 에스이 | 살충 화합물 |
| WO2018162312A1 (en) | 2017-03-10 | 2018-09-13 | Basf Se | Spirocyclic derivatives |
| WO2018166855A1 (en) | 2017-03-16 | 2018-09-20 | Basf Se | Heterobicyclic substituted dihydroisoxazoles |
| KR102596592B1 (ko) | 2017-03-28 | 2023-10-31 | 바스프 에스이 | 살충 화합물 |
| CN110461854A (zh) | 2017-03-31 | 2019-11-15 | 巴斯夫欧洲公司 | 制备手性2,3-二氢噻唑并[3,2-a]嘧啶-4-鎓化合物的方法 |
| WO2018192793A1 (en) | 2017-04-20 | 2018-10-25 | Basf Se | Substituted rhodanine derivatives |
| EP3615530B1 (en) | 2017-04-26 | 2021-04-14 | Basf Se | Substituted succinimide derivatives as pesticides |
| CN110546152B (zh) | 2017-05-10 | 2023-09-08 | 巴斯夫欧洲公司 | 双环农药化合物 |
| WO2018224455A1 (en) | 2017-06-07 | 2018-12-13 | Basf Se | Substituted cyclopropyl derivatives |
| EP3638677A1 (en) | 2017-06-16 | 2020-04-22 | Basf Se | Mesoionic imidazolium compounds and derivatives for combating animal pests |
| EP3642203A1 (en) | 2017-06-19 | 2020-04-29 | Basf Se | Substituted pyrimidinium compounds and derivatives for combating animal pests |
| WO2018234488A1 (en) | 2017-06-23 | 2018-12-27 | Basf Se | Substituted cyclopropyl derivatives |
| WO2019042932A1 (en) | 2017-08-31 | 2019-03-07 | Basf Se | METHOD FOR CONTROLLING RICE PARASITES IN RICE |
| EP3453706A1 (en) | 2017-09-08 | 2019-03-13 | Basf Se | Pesticidal imidazole compounds |
| US11399543B2 (en) | 2017-10-13 | 2022-08-02 | Basf Se | Substituted 1,2,3,5-tetrahydroimidazo[1,2-a]pyrimidiniumolates for combating animal pests |
| JP2021503465A (ja) | 2017-11-16 | 2021-02-12 | アビスタ ファーマ ソリューションズ，インコーポレーテッド | 単一エナンチオマーの抗寄生生物化合物 |
| SI3723739T1 (sl) | 2017-12-15 | 2024-08-30 | Tarsus Pharmaceuticals, Inc. | Paraziticidni pripravki na osnovi izoksazolina in njihova uporaba za zdravljenje blefaritisa |
| WO2019121143A1 (en) | 2017-12-20 | 2019-06-27 | Basf Se | Substituted cyclopropyl derivatives |
| UA127604C2 (uk) | 2017-12-21 | 2023-11-01 | Басф Се | Пестицидні сполуки |
| AU2019211978B2 (en) | 2018-01-09 | 2024-08-22 | Basf Se | Silylethynyl hetaryl compounds as nitrification inhibitors |
| WO2019137995A1 (en) | 2018-01-11 | 2019-07-18 | Basf Se | Novel pyridazine compounds for controlling invertebrate pests |
| KR102730587B1 (ko) | 2018-02-28 | 2024-11-14 | 바스프 에스이 | 질화작용 저해제로서의 n-관능화 알콕시 피라졸 화합물의 용도 |
| PE20211753A1 (es) | 2018-02-28 | 2021-09-06 | Basf Se | Uso de alcoxipirazoles como inhibidores de la nitrificacion |
| WO2019166558A1 (en) | 2018-02-28 | 2019-09-06 | Basf Se | Use of pyrazole propargyl ethers as nitrification inhibitors |
| WO2019175712A1 (en) | 2018-03-14 | 2019-09-19 | Basf Corporation | New uses for catechol molecules as inhibitors to glutathione s-transferase metabolic pathways |
| WO2019175713A1 (en) | 2018-03-14 | 2019-09-19 | Basf Corporation | New catechol molecules and their use as inhibitors to p450 related metabolic pathways |
| WO2019185413A1 (en) | 2018-03-27 | 2019-10-03 | Basf Se | Pesticidal substituted cyclopropyl derivatives |
| KR102727205B1 (ko) | 2018-05-15 | 2024-11-06 | 바스프 에스이 | 벤즈피리목산 및 옥사조술필을 포함하는 혼합물 및 이의 용도 및 이의 적용 방법 |
| WO2019224092A1 (en) | 2018-05-22 | 2019-11-28 | Basf Se | Pesticidally active c15-derivatives of ginkgolides |
| WO2020002472A1 (en) | 2018-06-28 | 2020-01-02 | Basf Se | Use of alkynylthiophenes as nitrification inhibitors |
| PL3826983T3 (pl) | 2018-07-23 | 2024-09-09 | Basf Se | Zastosowanie podstawionych 2-tiazolin jako inhibitorów nitryfikacji |
| CN112424147B (zh) | 2018-07-23 | 2023-06-30 | 巴斯夫欧洲公司 | 取代噻唑烷化合物作为硝化抑制剂的用途 |
| EP3613736A1 (en) | 2018-08-22 | 2020-02-26 | Basf Se | Substituted glutarimide derivatives |
| EP3628157A1 (en) | 2018-09-28 | 2020-04-01 | Basf Se | Method of controlling insecticide resistant insects and virus transmission to plants |
| AU2019348280A1 (en) | 2018-09-28 | 2021-04-22 | Basf Se | Method of controlling pests by seed treatment application of a mesoionic compound or mixture thereof |
| EP3628158A1 (en) | 2018-09-28 | 2020-04-01 | Basf Se | Pesticidal mixture comprising a mesoionic compound and a biopesticide |
| EP3628156A1 (en) | 2018-09-28 | 2020-04-01 | Basf Se | Method for controlling pests of sugarcane, citrus, rapeseed, and potato plants |
| EP3643705A1 (en) | 2018-10-24 | 2020-04-29 | Basf Se | Pesticidal compounds |
| US12459934B2 (en) | 2018-11-28 | 2025-11-04 | Basf Se | Pesticidal compounds |
| WO2020126591A1 (en) | 2018-12-18 | 2020-06-25 | Basf Se | Substituted pyrimidinium compounds for combating animal pests |
| EP3696177A1 (en) | 2019-02-12 | 2020-08-19 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
| US12502377B2 (en) | 2019-04-04 | 2025-12-23 | Tarsus Pharmaceuticals, Inc. | Method of eradicating ticks that attach to humans using lotilaner formulations |
| EP3769623A1 (en) | 2019-07-22 | 2021-01-27 | Basf Se | Mesoionic imidazolium compounds and derivatives for combating animal pests |
| BR112021019416A2 (pt) | 2019-05-29 | 2021-12-07 | Basf Se | Compostos, composição, métodos de proteção de safras e de combate, controle, prevenção ou proteção contra infestações, método não terapêutico de tratamento de animais infestados, semente e uso |
| EP3766879A1 (en) | 2019-07-19 | 2021-01-20 | Basf Se | Pesticidal pyrazole derivatives |
| WO2022061914A1 (zh) * | 2020-09-28 | 2022-03-31 | 台州臻挚生物科技有限公司 | 一种3,5-二卤三氟苯乙酮及其衍生物的制备方法 |
| EP4288398A1 (en) | 2021-02-02 | 2023-12-13 | Basf Se | Synergistic action of dcd and alkoxypyrazoles as nitrification inhibitors |
| US20240270658A1 (en) | 2021-05-21 | 2024-08-15 | Basf Se | Use of an N-Functionalized Alkoxy Pyrazole Compound as Nitrification Inhibitor |
| US20240351959A1 (en) | 2021-05-21 | 2024-10-24 | Basf Se | Use of ethynylpyridine compounds as nitrification inhibitors |
| CA3223077A1 (en) | 2021-06-21 | 2022-12-29 | Barbara Nave | Metal-organic frameworks with pyrazole-based building blocks |
| WO2022271933A1 (en) | 2021-06-23 | 2022-12-29 | Kimtron, Inc. | System and method for ultra-close proximity irradiation of rotating biomass |
| WO2023203066A1 (en) | 2022-04-21 | 2023-10-26 | Basf Se | Synergistic action as nitrification inhibitors of dcd oligomers with alkoxypyrazole and its oligomers |
| AU2023317620A1 (en) | 2022-08-02 | 2025-02-13 | Basf Se | Pyrazolo pesticidal compounds |
| CN117263825A (zh) * | 2023-11-23 | 2023-12-22 | 内蒙古百灵科技有限公司 | 一种双甲脒结晶的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010084067A2 (en) * | 2009-01-22 | 2010-07-29 | Syngenta Participations Ag | Insecticidal compounds |
| CA2790963A1 (en) * | 2010-02-25 | 2011-09-01 | Syngenta Participations Ag | Process for the preparation of isoxazoline derivatives |
| CN103270036B (zh) * | 2010-08-05 | 2015-11-25 | 佐蒂斯有限责任公司 | 作为抗寄生物剂的异噁唑啉衍生物 |
| WO2012086462A1 (ja) * | 2010-12-20 | 2012-06-28 | 日本曹達株式会社 | イソオキサゾリン化合物および有害生物防除剤 |
| WO2012120399A1 (en) * | 2011-03-10 | 2012-09-13 | Pfizer Inc. | Spirocyclic isoxazoline derivatives as antiparasitic agents |
-
2013
- 2013-08-28 RS RS20180636A patent/RS57284B1/sr unknown
- 2013-08-28 SI SI201331062T patent/SI2890699T1/en unknown
- 2013-08-28 DK DK13756985.1T patent/DK2890699T3/en active
- 2013-08-28 JP JP2015529970A patent/JP6109942B2/ja active Active
- 2013-08-28 NZ NZ704175A patent/NZ704175A/en unknown
- 2013-08-28 AU AU2013308887A patent/AU2013308887B2/en active Active
- 2013-08-28 ES ES13756985.1T patent/ES2671271T3/es active Active
- 2013-08-28 BR BR112015004135A patent/BR112015004135B8/pt active IP Right Grant
- 2013-08-28 HU HUE13756985A patent/HUE037667T2/hu unknown
- 2013-08-28 RU RU2015107052A patent/RU2614978C2/ru active
- 2013-08-28 CN CN201380044821.9A patent/CN104812758B/zh active Active
- 2013-08-28 HR HRP20180861TT patent/HRP20180861T1/hr unknown
- 2013-08-28 PL PL13756985T patent/PL2890699T3/pl unknown
- 2013-08-28 TR TR2018/07735T patent/TR201807735T4/tr unknown
- 2013-08-28 LT LTEP13756985.1T patent/LT2890699T/lt unknown
- 2013-08-28 CA CA2881467A patent/CA2881467C/en active Active
- 2013-08-28 US US14/422,098 patent/US9200003B2/en active Active
- 2013-08-28 KR KR1020157004953A patent/KR101736643B1/ko active Active
- 2013-08-28 EP EP13756985.1A patent/EP2890699B1/en active Active
- 2013-08-28 MX MX2015002679A patent/MX351463B/es active IP Right Grant
- 2013-08-28 PT PT137569851T patent/PT2890699T/pt unknown
- 2013-08-28 WO PCT/US2013/056945 patent/WO2014036056A1/en not_active Ceased
- 2013-08-30 AR ARP130103110A patent/AR092409A1/es unknown
- 2013-12-13 NO NO13863231A patent/NO2931268T3/no unknown
-
2015
- 2015-01-30 ZA ZA2015/00728A patent/ZA201500728B/en unknown
- 2015-02-11 CL CL2015000332A patent/CL2015000332A1/es unknown
- 2015-02-27 PH PH12015500441A patent/PH12015500441A1/en unknown
-
2018
- 2018-06-13 CY CY181100619T patent/CY1120611T1/el unknown
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