LT2866797T - Stabili injekuojama neurokinino 1 receptoriaus antagonisto farmacinė kompozicija ir jos gamybos būdas - Google Patents
Stabili injekuojama neurokinino 1 receptoriaus antagonisto farmacinė kompozicija ir jos gamybos būdasInfo
- Publication number
- LT2866797T LT2866797T LTEP12756353.4T LT12756353T LT2866797T LT 2866797 T LT2866797 T LT 2866797T LT 12756353 T LT12756353 T LT 12756353T LT 2866797 T LT2866797 T LT 2866797T
- Authority
- LT
- Lithuania
- Prior art keywords
- neurokinin
- preparation
- pharmaceutical composition
- receptor antagonist
- injectable pharmaceutical
- Prior art date
Links
- 229940123821 Neurokinin 1 receptor antagonist Drugs 0.000 title 1
- PFPSZGPAQFBVHZ-UHFFFAOYSA-N n-(3-chlorophenyl)-2-[(4-phenyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical group ClC1=CC=CC(NC(=O)CSC=2N(C(C=3C=CN=CC=3)=NN=2)C=2C=CC=CC=2)=C1 PFPSZGPAQFBVHZ-UHFFFAOYSA-N 0.000 title 1
- 239000002742 neurokinin 1 receptor antagonist Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fencing (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2012/002854 WO2014005606A1 (en) | 2012-07-06 | 2012-07-06 | Stable injectable pharmaceutical composition of neurokinin 1 receptor antagonist and process for preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT2866797T true LT2866797T (lt) | 2020-06-25 |
Family
ID=46826407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP12756353.4T LT2866797T (lt) | 2012-07-06 | 2012-07-06 | Stabili injekuojama neurokinino 1 receptoriaus antagonisto farmacinė kompozicija ir jos gamybos būdas |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20150165045A1 (lt) |
| EP (1) | EP2866797B1 (lt) |
| CY (1) | CY1123370T1 (lt) |
| DK (1) | DK2866797T3 (lt) |
| ES (1) | ES2798103T3 (lt) |
| HR (1) | HRP20201138T1 (lt) |
| HU (1) | HUE051147T2 (lt) |
| LT (1) | LT2866797T (lt) |
| PL (1) | PL2866797T3 (lt) |
| PT (1) | PT2866797T (lt) |
| RS (1) | RS60599B1 (lt) |
| SI (1) | SI2866797T1 (lt) |
| SM (1) | SMT202000385T1 (lt) |
| WO (1) | WO2014005606A1 (lt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3054980B1 (en) | 2013-10-08 | 2019-09-04 | InnoPharma, Inc. | Aprepitant oral liquid formulations |
| JP2017502973A (ja) * | 2013-12-30 | 2017-01-26 | オンコプレフェント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 癌を予防する方法において使用するためのニューロキニン−1受容体アンタゴニスト |
| EP3171894B1 (en) * | 2014-07-24 | 2021-03-24 | Plus Vitech, S.L. | Neurokinin-1 receptor antagonist composition for treatment of diseases and conditions of the respiratory tract |
| EP3193830B1 (en) | 2014-09-19 | 2023-11-01 | Heron Therapeutics, Inc. | Emulson formulations of aprepitant |
| US10610532B2 (en) * | 2015-08-03 | 2020-04-07 | Leiutis Pharmaceuticals Pvt. Ltd. | Liquid formulations of fosaprepitant |
| US9913853B2 (en) | 2015-11-03 | 2018-03-13 | Cipla Limited | Stabilized liquid fosaprepitant formulations |
| CA3013288A1 (en) * | 2016-02-01 | 2017-08-10 | Heron Therapeutics, Inc. | Emulsion comprising an nk-1 receptor antagonist |
| US9974742B2 (en) | 2016-02-01 | 2018-05-22 | Heron Therapeutics, Inc. | Emulsion formulations of an NK-1 receptor antagonist and uses thereof |
| PH12018502524B1 (en) * | 2016-06-06 | 2022-04-27 | Helsinn Healthcare Sa | Physiologically balanced injectable formulations of fosnetupitant |
| CN113288862B (zh) * | 2016-08-03 | 2023-06-02 | 珠海贝海生物技术有限公司 | 含阿瑞吡坦的组合物及其制备方法和应用 |
| WO2019152430A1 (en) * | 2018-01-30 | 2019-08-08 | Heron Therapeutics, Inc. | Method of administering emulsion formulations of an nk-1 receptor antagonist |
| US11654154B2 (en) | 2019-01-29 | 2023-05-23 | Navinta Iii Inc | Process for preparing injectable Fosaprepitant Dimeglumine compositions having improved storage stability |
| CN112168788B (zh) * | 2019-07-01 | 2022-07-19 | 中国医学科学院药物研究所 | 静脉注射用阿瑞匹坦胶束无菌冻干制剂及其制备方法 |
| CN110559255B (zh) * | 2019-09-06 | 2022-08-19 | 南京医科大学 | Zl006温敏凝胶及其制备方法 |
| JP7606633B2 (ja) * | 2022-04-14 | 2024-12-25 | ウィズダム・ファーマスーティカル・カンパニー・リミテッド | 医薬組成物及びアプレピタント注射液並びに凍結乾燥粉末注射剤 |
| CN115944745B (zh) * | 2022-12-01 | 2024-03-22 | 石河子大学 | 一种具有聚集诱导发光性质的活性氧响应型药物控释体系及其制备方法和应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE195867T1 (de) | 1991-09-20 | 2000-09-15 | Glaxo Group Ltd | Neue medizinische indikation für tachykinin- antagonisten |
| TW385308B (en) | 1994-03-04 | 2000-03-21 | Merck & Co Inc | Prodrugs of morpholine tachykinin receptor antagonists |
| WO2006047279A2 (en) * | 2004-10-21 | 2006-05-04 | University Of Iowa Research Foundation | In situ controlled release drug delivery system |
| WO2007088483A1 (en) * | 2006-02-03 | 2007-08-09 | Glenmark Pahrmaceuticals Limited | Amorphous and crystalline forms of aprepitant and processes for the preparation thereof |
| WO2007128056A1 (en) * | 2006-05-03 | 2007-11-15 | Cnsbio Pty Ltd | Methods and composition for treatment of inflammatory pain |
| US20070265329A1 (en) | 2006-05-12 | 2007-11-15 | Devang Shah T | Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) |
| US20100151035A1 (en) * | 2007-03-13 | 2010-06-17 | Sandoz Ag | Pharmaceutical compositions of poorly soluble drugs |
| JP5714910B2 (ja) * | 2008-01-09 | 2015-05-07 | チャールストン ラボラトリーズ,インコーポレイテッド | 薬学的組成物 |
| WO2009155054A2 (en) * | 2008-05-29 | 2009-12-23 | Albany Molecular Research, Inc. | 5-ht3 receptor modulators, methods of making, and use thereof |
| EP2451274B1 (en) * | 2009-07-08 | 2017-10-04 | Charleston Laboratories, Inc. | Pharmaceutical compositions |
| HUP1000325A2 (en) * | 2010-06-18 | 2012-01-30 | Druggability Technologies Ip Holdco Jersey Ltd | Nanostructured aprepitant compositions and process for their preparation |
-
2012
- 2012-07-06 HU HUE12756353A patent/HUE051147T2/hu unknown
- 2012-07-06 PT PT127563534T patent/PT2866797T/pt unknown
- 2012-07-06 PL PL12756353T patent/PL2866797T3/pl unknown
- 2012-07-06 EP EP12756353.4A patent/EP2866797B1/en active Active
- 2012-07-06 LT LTEP12756353.4T patent/LT2866797T/lt unknown
- 2012-07-06 WO PCT/EP2012/002854 patent/WO2014005606A1/en not_active Ceased
- 2012-07-06 SM SM20200385T patent/SMT202000385T1/it unknown
- 2012-07-06 US US14/412,147 patent/US20150165045A1/en not_active Abandoned
- 2012-07-06 RS RS20200846A patent/RS60599B1/sr unknown
- 2012-07-06 DK DK12756353.4T patent/DK2866797T3/da active
- 2012-07-06 SI SI201231807T patent/SI2866797T1/sl unknown
- 2012-07-06 HR HRP20201138TT patent/HRP20201138T1/hr unknown
- 2012-07-06 ES ES12756353T patent/ES2798103T3/es active Active
-
2020
- 2020-04-17 US US16/851,779 patent/US20200237920A1/en not_active Abandoned
- 2020-07-07 CY CY20201100624T patent/CY1123370T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RS60599B1 (sr) | 2020-08-31 |
| SMT202000385T1 (it) | 2020-11-10 |
| WO2014005606A1 (en) | 2014-01-09 |
| EP2866797A1 (en) | 2015-05-06 |
| EP2866797B1 (en) | 2020-04-29 |
| SI2866797T1 (sl) | 2020-08-31 |
| ES2798103T3 (es) | 2020-12-09 |
| PL2866797T3 (pl) | 2020-11-02 |
| CY1123370T1 (el) | 2021-12-31 |
| US20200237920A1 (en) | 2020-07-30 |
| DK2866797T3 (da) | 2020-08-03 |
| US20150165045A1 (en) | 2015-06-18 |
| PT2866797T (pt) | 2020-07-22 |
| HRP20201138T1 (hr) | 2020-10-30 |
| HUE051147T2 (hu) | 2021-03-01 |
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