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KR970706852A - 피부 손상을 적게 일으키는 수증기 투과성 상처 드레싱(low trauma wound dressing with improved moisture vapor permeability) - Google Patents

피부 손상을 적게 일으키는 수증기 투과성 상처 드레싱(low trauma wound dressing with improved moisture vapor permeability) Download PDF

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KR970706852A
KR970706852A KR1019970702959A KR19970702959A KR970706852A KR 970706852 A KR970706852 A KR 970706852A KR 1019970702959 A KR1019970702959 A KR 1019970702959A KR 19970702959 A KR19970702959 A KR 19970702959A KR 970706852 A KR970706852 A KR 970706852A
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acrylate
wound dressing
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microspheres
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KR100367151B1 (ko
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델가도 조아킴
제이. 궤츠 리차드
에프. 실버 스펜서
에이치. 루카스트 도날드
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테릴 켄트 컬리
미네소타 마이닝 앤드 매뉴팩츄어링 컴패니
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/24—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/023—Adhesive bandages or dressings wound covering film layers without a fluid retention layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • A61L15/585—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00655—Plasters adhesive
    • A61F2013/00659—Plasters adhesive polymeric base
    • A61F2013/00663—Plasters adhesive polymeric base acrylic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00655—Plasters adhesive
    • A61F2013/0071—Plasters adhesive containing active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00727—Plasters means for wound humidity control
    • A61F2013/00761—Plasters means for wound humidity control with permeable adhesive layers
    • A61F2013/00774—Plasters means for wound humidity control with permeable adhesive layers arranged in discrete dots
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/249921—Web or sheet containing structurally defined element or component
    • Y10T428/249953—Composite having voids in a component [e.g., porous, cellular, etc.]
    • Y10T428/249981—Plural void-containing components
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/249921—Web or sheet containing structurally defined element or component
    • Y10T428/249953—Composite having voids in a component [e.g., porous, cellular, etc.]
    • Y10T428/249982—With component specified as adhesive or bonding agent
    • Y10T428/249983—As outermost component
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/249921—Web or sheet containing structurally defined element or component
    • Y10T428/249953—Composite having voids in a component [e.g., porous, cellular, etc.]
    • Y10T428/249982—With component specified as adhesive or bonding agent
    • Y10T428/249984—Adhesive or bonding component contains voids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/249921—Web or sheet containing structurally defined element or component
    • Y10T428/249953—Composite having voids in a component [e.g., porous, cellular, etc.]
    • Y10T428/249986—Void-containing component contains also a solid fiber or solid particle
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
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    • Y10T428/28—Web or sheet containing structurally defined element or component and having an adhesive outermost layer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/28—Web or sheet containing structurally defined element or component and having an adhesive outermost layer
    • Y10T428/2852—Adhesive compositions
    • Y10T428/2878—Adhesive compositions including addition polymer from unsaturated monomer
    • Y10T428/2891—Adhesive compositions including addition polymer from unsaturated monomer including addition polymer from alpha-beta unsaturated carboxylic acid [e.g., acrylic acid, methacrylic acid, etc.] Or derivative thereof

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  • Veterinary Medicine (AREA)
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  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials For Medical Uses (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

본 발명은 수중기 투과성 배킹층과, 점착성, 실질적 용매 불용성, 용매 분산성, 아크릴계 탄성 중합체성, 압감 접착성 미세구로 이루어진 연속적 입자 함유 접착층을 포함하는 피부 손상을 적게 일으키는 수중기 투과성의 상처 드레싱에 관한 것이다.

Description

피부 손상을 적게 일으키는 수증기 투과성 상처 드레싱(LOW TRAUMA WOUND DRESSING WITH IMPROVED MOISTURE VAPOR PERMEABILITY)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (31)

  1. 수증기 투과성 배킹층과, 점착성, 실질적 용매 불용성, 용매 분산성, 아크릴계 탄성 중합체성, 압감 접착성 미세구로 이루어진 연속적 입자 함유 접착층을 포함하는, 피부 손상을 적게 일으키는 수증기 투과성의 상처 드레싱.
  2. 제1항에 있어서, 하나의 접착층에 102.5이상의 박테리아 감소능을 제공하는 항균계를 추가로 포함하는 상처 드레싱.
  3. 제2항에 있어서, 상기 항균계가 적어도 항균제와 전이제를 포함하는 상처 드레싱.
  4. 제3항에 있어서, 상기 항균제가 클로르헥시딘인 상처 드레싱
  5. 제4항에 있어서, 상기 전이제가 글리세린인 상처 드레싱.
  6. 제2항에 있어서, 하나의 접착층이 105이상의 박테리아 감소능을 갖는 상처 드레싱.
  7. 제2항에 있어서, 대부분의 접착성 미세구가 미세구 직경의 약 10% 이상의 직경을 가지는 1개 이상의 내부 공극을 포함하고 있는 상처 드레싱.
  8. 제2항에 있어서, 대부분의 접착성 미세구가 미세구 직경의 약 30% 이상의 직경을 가지며 실질적으로 구형인 1개 이상의 내부 공극을 포함하고 있는 상처 드레싱.
  9. 제1항에 있어서, 접착성 미세구의 평균직경이 1μm 이상인 상처 드레싱.
  10. 제1항에 있어서, 상기 접착성 미세구가 유리전이 온도 약-20℃ 이하의 아크릴레이트 중합체로 제조되는 상처 드레싱.
  11. 제1항에 있어서, 상기 접착성 미세구가 n-부틸아크릴레이트, sec-부틸아크릴레이트, 2-마틸부틸아크릴레이트, 4-메틸-2-펜틸아크릴레이트, 2-에틸헥실아크릴레이트, 이소옥틸아크릴레이트, 이소노닐아크릴레이트,이소아밀아크릴레이트, 이소데실아클릴레이트 및 이소데실메타크릴레이트로 이루어지는 군으로부터 선택되는 하나 이상의 알킬아크릴레이트 또는 알킬메타크릴레이트 에스테르를 포함하는 상처 드레싱.
  12. 제1항에 있어서, 상기 접착성 미세구가 (a) 약 75중량% 이상의 하나 이상의 아크릴레이트 또는 메타크릴레이트 에스테르와, (b) 그 나머지의 하나 이상의 극성 단량체를 포함하는 상처 드레싱.
  13. 제12항에 있어서, 상기 알킬아크릴레이트가 (a) 비-3급 C4-12알콜의 아크릴레이트 또는 메타그릴레이트 에스테르와, (b) 알콜 분자당 평균 약 4-12개의 탄소 원자를 지닌 비-3급 C4-12알콜 혼합물의 아크릴레이트 또는 메타크릴레이트 에스테르로 이루어지는 군으로부터 선택되는 상처 드레싱.
  14. 제12항에 있어서, 상기 극성 단량체가 아크릴산, 메타아크릴산, 이타콘산, 크로톤산, 말레인사, 푸마르산 및 이들의 염으로 이루어지는 군에서 선택되는 상처 드레싱.
  15. 제1항에 있어서, 상기 접착성 미세구가 (a) 하나 이상의 알킬아크릴레이트 또는 알킬메타크릴레이트 에스테르 약 75중량% 이상과, (b)(A) 아크릴산, 메타크릴산, 이타콘산, 크로톤산, 말레인산, 푸마르산, 이들의 염으로 이루어지는 군에서 선택된 극성 단량체, (B) 친수성 N-비닐락탐 및 (C) 알킬렌옥사이드 단위의 수가 평균 약 3 내지 40인 친수성 알킬렌옥사이드 아크릴레이트의 혼합물 25중량%까지를 포함하는 상처 드레싱.
  16. 제1항에 있어서, 상기 접착제가 (a) 약 70 내지 90중량%의 미세구와, (b) 약 10 내지 30중량%의, 현수된 중합체 부위를 가진 탄성중합체성 중합체 골격을 포함하는 공중합체 결합제를 포함하고, 상기 중합체 골격은(A) 비-3급 C4-12알콜의 아크릴레이트 또는 메타크릴레이트 에스테르와, 또는 알콜 분자당 평균 약 4-12개의 탄소 원자를 지닌 비-3급 C1-14알콜 혼합물의 아크릴레이트 또는 메타크릴레이트 에스테르를 포함하는 제1의 단량체 약 50 내지 98중량%, (B) 제1의 단량체와 중합 가능한 제2의 극성 단량체 약 1 내지 20중량% 및 (C) 일반식 X-(Y)n-Z(식중, X는 단량체 A 및 B와 공중합될 수 있는 비닐기이고, Y는 2가의 결합기이며, n은 0 또는 1이고, Z는 평균 분자량 약 2,000 내지 약 30,000이고, 공중합 조건하에서 실질적으로 비반응성이며 20。C보다 큰 유리전이 온도를 지닌 1가의 중합체 부위이다)으로 표현되는 제3의 약 0 내지 30 중량%를 포함하는 상처 드레싱.
  17. 제16항에 있어서, 상기 접착성 미세구가 하나 이상의 극성 단량체를 추가로 포함하는 상처 드레싱.
  18. 제1항에 있어서, 상기 미세구가 (a) n-부틸아크릴레이트, sec-부틸아크릴레이트, 2-메틸부틸아크릴레이트, 4-메틸-2-펜틸아크릴레이트, 2-에틸헥실아크릴레이트, 이소옥틸아크릴레이트, 이소노닐아크릴레이트, 이소아밀아크릴레이트, 이소데실아크릴레이트 및 이소데실타크릴레이트로 이루어진 군에서 선택된 알킬아크릴레이트 에스테르 약 85중량% 중량 이상과, (b) 아크릴산, 메타아크릴산, 이타콘산, 크로톤산, 말레인산, 푸마르산 및 이들의 염으로 이루어진 군에서 선택된 하나 이상의 극성 단량체 15중량%까지의 포함하는 상처 드레싱.
  19. 제17항에 있어서, 상기 제2단량체가 아크릴산, 메타크릴산, 이타콘산, N-비닐피롤리돈, 아크릴아미드, 메타크릴아미드, 아크릴니트릴 및 메타크리로니트릴로 이루어진 군에서 선택되는 상처 드레싱.
  20. 제17항에 있어서, 대부분의 접착성 미세구가 미세구 직경의 약 10% 이상의 직경을 가지며 실질적으로 구형인 1개 이상의 공극을 포함하는 있는 상처 드레싱.
  21. 제10항에 있어서, (a) 상기 접착성 미세구가 비이온 단량체로 구성되고 대분이 물에 유화가능한 친유성알킬아크릴레이트 또는 메타크릴레이트 에스테르를 포함하는 상처 드레싱.
  22. 제1항에 있어서, 상기 접착성 미세구가 (A) 이소옥틸아클리레이트, 4-메틸-2-펜틸 아크릴레이트, 2-메틸부틸 아크릴레이트, sec-부틸아크릴레이트, n-부틸아크릴레이트, 2-에틸헥실 아크릴레이트로 이루어지는 군에서 서택되는 하나 이상의, 물에 유화 가능한 친유성 알킬 아크릴레이트 에스테르 약 90 내지 약 99.5중량% 및 (B) 트리메틸아민 메타크릴이미드, 트리메틸아민 p-비닐벤즈이미드, 암모늄아크릴레이트, 나트륨아크릴레이트, N,N-디메틸-N-(b-메타크릴옥시에틸)암모늄 프로피어네이트 베타인, 1,1-디메틸-1-(2,3-디히드록시프로필)아민 메타크릴이미드, 4,4,9-트리메틸-4-4-아조니아-7-옥소-8-옥사-9-데센-1-술폰네이트, 1,1-디메틸-1-(2,3-디히드록시프로필)아민 메타크릴이미드 및 무수 말레인산으로 이루어지는 군에서 선택된 하나 이상의 부가의 단량체 약 0.5 내지 10중량%를 필수 성분으로 포함하고, (b) 상기 접착성 미세구가 유화제의 임계 미셸 농도 보다 높은 농도의 적절한 유화제의 존재하에서 수상 현탁액 중합에 의해서 제조되는, 상처 드레싱.
  23. 제22항에 있어서, 상시 접착성 미세구는 알킬 아크릴레이트 에스테르 약 98 내지 약 99.5중량% 및 부가의 단량체 0.5 내지 2중량%를 필수성분으로 포함하는 상처 드레싱.
  24. 제1항에 있어서, 상기 배킹이 폴리우레탄인 상처 드레싱.
  25. 제24항에 있어서, 상기 배킹이 500g/㎡ 이상의 MVTPup을 가지는 투명한 폴리우레탄인 상처 드레싱.
  26. 수중기 투과성 배킹과, 점착성, 실질적 용매 불용성, 용매 분산성, 아크릴계 탄성중합체성, 압감 접착성 미세구로 이루어진 복수개의 접착층과의 라미네이트층을 포함하는, 피부 손상을 적게 일으키는 수중기 투과성의 상처 드레싱.
  27. 제26항에 있어서, 대부분의 접착성 미세구가 미세구 직경의 약 10% 이상의 직경을 가지며 실질적으로 구형인 1개 이상의 내부 공극을 포함하고 있는 상처 드레싱.
  28. 제26항에 있어서, 상기 접착성 미세구가 (a) 하나 이상의 알킬아크릴레이트 또는 알킬메타크릴레이트 에스테르 약 75중량% 이상과, (b)(A) 아크릴산, 메타크릴산, 이타콘산, 크로톤산, 말레인산, 푸마르산, 이들의 염으로 이루어지는 군에서 선택된 극성 단량체, (B) 친수성 N-비닐락탐 및 (C) 알킬렌옥사이드 단위의 수가 평균 약 3 내지 40인 친수성 알킬렌옥사이드 아크릴레이트의 혼합물 25중량%까지를 포함하는 상처 드레싱.
  29. 제1항에 있어서, 상기 접착제가 (a) 약 70 내지 99중량%의 미세구와, (b) 약 1 내지 30중량%의, 현수된 중합체 부위를 가진 탄성중합체성 중합체 골격을 포함하는 공중합체 결합제를 포함하고, 상기 중합체 골격은 (A) 비-3급 C4-12알콜의 아크릴레이트 또는 메타크릴레이트 에스테르와, 또는 알콜 분자당 평균 약 4-12개의 탄소 원자를 지닌 비-3급 C1-14알콜 혼합물의 아크릴레이트 또는 메타크릴레이트 에스테르를 포함하는 제1의 단량체 약 50 내지 98중량%, (B) 제1의 단량체와 중합 가능한 제2의 극성 단량체 약 1 내지 20중량% 및 (C) 일반식 X-(Y)n-Z(식중, X는 단량체 A 및 B와 공중합될 수 있는 비닐기이고, Y는 2가의 결합기이며, n은 0 또는 1이고, Z는 평균 분자량 약 2,000 내지 약 30,000이고, 공중합 조건하에서 실질적으로 비반응성이며 20。C보다 큰 유리전이 온도를 지닌 1가의 중합체 부위이다)으로 표현되는 제3의 약 1 내지 30중량%를 포함하는 상처 드레싱.
  30. 제26항에 있어서, (a) 상기 접착성 미세구가 비이온 단량체로 구성되고 대분이 물에 유화가능한 친유성 알킬아크릴레이트 또는 메탈크릴레이트 에스테르를 포함하고, (b) 상기 접착성 미세구가 유화제의 임계 미셸 농도 보다 높은 농도의 적절한 유화제와 적합한 중합 현탁액 안정화제 존재하에서 수상 현탁액 중합에 의해서 제조되는, 상처 드레싱.
  31. 제26항에 있어서, 상기 배킹이 폴리우레탄인 상처 드레싱.
    ※ 참고사항 : 최초출원 내용에 의하여 공개되는 것임.
KR1019970702959A 1994-11-04 1995-09-25 피부 손상을 적게 유발시키는 향상된 수증기 투과성의 상처드레싱 Expired - Fee Related KR100367151B1 (ko)

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US08/334,683 US5614310A (en) 1994-11-04 1994-11-04 Low trauma wound dressing with improved moisture vapor permeability
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BR9509599A (pt) 1998-01-06
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US5614310A (en) 1997-03-25
CN1108830C (zh) 2003-05-21
US5908693A (en) 1999-06-01
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WO1996014094A1 (en) 1996-05-17
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