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KR970705386A - 치아 및 구강 뼈의 유지방법(methods of maintaining teeth and oralbone) - Google Patents

치아 및 구강 뼈의 유지방법(methods of maintaining teeth and oralbone)

Info

Publication number
KR970705386A
KR970705386A KR1019970701096A KR19970701096A KR970705386A KR 970705386 A KR970705386 A KR 970705386A KR 1019970701096 A KR1019970701096 A KR 1019970701096A KR 19970701096 A KR19970701096 A KR 19970701096A KR 970705386 A KR970705386 A KR 970705386A
Authority
KR
South Korea
Prior art keywords
compound
oralbone
methods
maintaining teeth
rti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019970701096A
Other languages
English (en)
Inventor
윌리엄 로크릿지 세일즈
Original Assignee
스트링거 피터 지
일라이 릴리 앤드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 스트링거 피터 지, 일라이 릴리 앤드 캄파니 filed Critical 스트링거 피터 지
Publication of KR970705386A publication Critical patent/KR970705386A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

하기 화학식(Ⅰ)의 화합물 또는 이의 약제학적으로 허용가능한 염 또는 용매화합물을 이룰 필요로 하는 사람에게 유효량 투여함을 포함하는, 치아 및 구강 뼈를 유지하는 방법:
상기 식에서, R1및 R3는 독립적으로 수소, -CH, (a) 또는 (b)(여기서, Ar은 선택적으로 치환된 페닐이다)이고, R2는 피롤리딘, 헥사메틸렌이미노 및 피페리디노로 이루어진 군으로부터 선택된다:

Description

치아 및 구강 뻐의 유지방법(METHODS OF MAINTAINING TEETH AND ORALBONE)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 하기 화학식(Ⅰ)의 화합물 또는 이의 약제학적으로 허용가능한 염 또는 용매화합물을 이룰 필요로 하는 사람에게 유효량 투여함을 포함하는, 치아 및 구강 뼈를 유지하는 방법;
    상기 식에서, R1및 R3는 독립적으로 수소, -CH3,(C1-C6알킬),(여기서, Ar은 선택적으로 치환된 페닐이다)이고, R2는 피롤리딘, 헥사메틸렌이미노 및 피페리디노로 이루어진 군으로부터 선택된다.
  2. 제1항에 있어서, 상기 화합물이 이의 염화수소염인 방법.
  3. 제1항에 있어서, 상기 투여가 예방용인 방법.
  4. 제1항에 있어서, 상기 화합물이 하기 화합물 또는 이의 염화수소염인 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019970701096A 1994-08-22 1995-08-21 치아 및 구강 뼈의 유지방법(methods of maintaining teeth and oralbone) Withdrawn KR970705386A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29423794A 1994-08-22 1994-08-22
US08/294,237 1994-08-22
PCT/US1995/010582 WO1996005829A1 (en) 1994-08-22 1995-08-21 Methods of maintaining teeth and oral bone

Publications (1)

Publication Number Publication Date
KR970705386A true KR970705386A (ko) 1997-10-09

Family

ID=23132491

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019970701096A Withdrawn KR970705386A (ko) 1994-08-22 1995-08-21 치아 및 구강 뼈의 유지방법(methods of maintaining teeth and oralbone)

Country Status (14)

Country Link
EP (1) EP0769946A4 (ko)
JP (1) JPH10504573A (ko)
KR (1) KR970705386A (ko)
AU (1) AU692598B2 (ko)
CA (1) CA2198108A1 (ko)
CZ (1) CZ52197A3 (ko)
FI (1) FI970713A7 (ko)
HU (1) HUT76891A (ko)
IL (1) IL115017A0 (ko)
MX (1) MX9701331A (ko)
NO (1) NO970784D0 (ko)
WO (1) WO1996005829A1 (ko)
YU (1) YU55495A (ko)
ZA (1) ZA956987B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075321A (en) * 1987-03-24 1991-12-24 University Of Pennsylvania Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes
TW366342B (en) * 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss

Also Published As

Publication number Publication date
FI970713A0 (fi) 1997-02-20
AU692598B2 (en) 1998-06-11
CZ52197A3 (en) 1997-08-13
YU55495A (sh) 1998-07-10
ZA956987B (en) 1997-02-21
CA2198108A1 (en) 1996-02-29
NO970784L (no) 1997-02-20
MX9701331A (es) 1997-05-31
FI970713L (fi) 1997-02-20
IL115017A0 (en) 1995-12-08
FI970713A7 (fi) 1997-02-20
EP0769946A4 (en) 1997-11-05
NO970784D0 (no) 1997-02-20
AU3408895A (en) 1996-03-14
EP0769946A1 (en) 1997-05-02
WO1996005829A1 (en) 1996-02-29
JPH10504573A (ja) 1998-05-06
HUT76891A (en) 1997-12-29

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 19970220

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid