KR970009594B1 - PROCESS FOR PRODUCING Ñß- L - ASPARTYL - L - PHENYLALANINE METHYL ESTER - Google Patents

PROCESS FOR PRODUCING Ñß- L - ASPARTYL - L - PHENYLALANINE METHYL ESTER Download PDF

Info

Publication number: KR970009594B1
Authority: KR; South Korea
Prior art keywords: produced; methyl ester; strong acidic; phenylalanine methyl; aspartyl
Prior art date: 1992-08-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

KR93016693A

Other languages

English (en)

Other versions

KR940003905A (ko

Inventor

Kyung-Suk Choe

Dae-Kwon Joo

Min-Soo Han

Ee-Nam Hwang

Hong-Kyu Choe

Original Assignee

Miwon Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-08-27

Filing date

1993-08-26

Publication date

1997-06-14

1993-08-26 Application filed by Miwon Co Ltd filed Critical Miwon Co Ltd

1994-03-14 Publication of KR940003905A publication Critical patent/KR940003905A/ko

1997-03-20 Priority to KR97009502A priority Critical patent/KR970009595B1/ko

1997-06-14 Application granted granted Critical

1997-06-14 Publication of KR970009594B1 publication Critical patent/KR970009594B1/ko

2013-08-26 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

KR93016693A 1992-08-27 1993-08-26 PROCESS FOR PRODUCING Ñß- L - ASPARTYL - L - PHENYLALANINE METHYL ESTER Expired - Fee Related KR970009594B1 (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
KR97009502A KR970009595B1 (en)	1992-08-27	1997-03-20	PROCESS FOR PRODUCING Ñß-L-ASPARTYL-L- PHENYLALANINE METHLY ESTER

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US93596192A	1992-08-27	1992-08-27
JP7/935,961		1992-08-27

Publications (2)

Publication Number	Publication Date
KR940003905A KR940003905A (ko)	1994-03-14
KR970009594B1 true KR970009594B1 (en)	1997-06-14

Family

ID=25467976

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR93016693A Expired - Fee Related KR970009594B1 (en)	1992-08-27	1993-08-26	PROCESS FOR PRODUCING Ñß- L - ASPARTYL - L - PHENYLALANINE METHYL ESTER

Country Status (8)

Country	Link
US (1)	US5334746A (ko)
KR (1)	KR970009594B1 (ko)
CH (1)	CH687825A5 (ko)
DE (1)	DE4328967A1 (ko)
FR (1)	FR2695128B1 (ko)
GB (1)	GB2270311B (ko)
IT (1)	IT1270852B (ko)
NL (1)	NL9301303A (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20010096940A (ko) *	2000-04-19	2001-11-08	고두모	알파-엘-아스파틸-엘-페닐알라닌 메틸에스테르 염산염의제조방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3492131A (en) *	1966-04-18	1970-01-27	Searle & Co	Peptide sweetening agents
US3786039A (en) *	1969-04-30	1974-01-15	Ajinomoto Kk	Method of producing alpha-l-aspartyl-l-phenylalanine lower alkyl esters
US3933781A (en) *	1973-11-05	1976-01-20	Monsanto Company	Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
JPS5223001A (en) *	1975-08-14	1977-02-21	Ajinomoto Co Inc	Process for elimination of formyl group
JPS58185545A (ja) *	1982-04-22	1983-10-29	Ajinomoto Co Inc	α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法
US4680403A (en) *	1985-01-17	1987-07-14	Ajinomoto Co., Inc.	Process for producing N-protected-α-L-aspartyl-L-phenylalanine methyl ester
DE3600731A1 (de) *	1986-01-13	1987-07-16	Green Cross Korea	Verfahren zur herstellung von (alpha)-l-aspartyl-l-phenylalaninmethylester
JPH0657719B2 (ja) *	1986-06-03	1994-08-03	味の素株式会社	α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの回収方法
KR910007940B1 (ko) *	1989-04-14	1991-10-04	주식회사 미원	L-페닐알라닌 메틸에스테르 염산염의 정석법

1993
- 1993-05-14 IT ITTO930336A patent/IT1270852B/it active IP Right Grant
- 1993-05-28 FR FR9306439A patent/FR2695128B1/fr not_active Expired - Fee Related
- 1993-07-23 NL NL9301303A patent/NL9301303A/nl active Search and Examination
- 1993-08-13 CH CH02407/93A patent/CH687825A5/de not_active IP Right Cessation
- 1993-08-17 GB GB9317124A patent/GB2270311B/en not_active Expired - Fee Related
- 1993-08-26 KR KR93016693A patent/KR970009594B1/ko not_active Expired - Fee Related
- 1993-08-27 DE DE4328967A patent/DE4328967A1/de not_active Withdrawn
- 1993-12-06 US US08/161,437 patent/US5334746A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CH687825A5 (de)	1997-02-28
FR2695128B1 (fr)	1995-07-07
GB2270311A (en)	1994-03-09
GB9317124D0 (en)	1993-09-29
IT1270852B (it)	1997-05-13
FR2695128A1 (fr)	1994-03-04
US5334746A (en)	1994-08-02
NL9301303A (nl)	1994-03-16
ITTO930336A1 (it)	1994-11-14
KR940003905A (ko)	1994-03-14
DE4328967A1 (de)	1994-03-03
GB2270311B (en)	1996-10-02
ITTO930336A0 (it)	1993-05-14

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FI20060782L (fi)	2006-08-30	Menetelmä beta-sitostanolirasvahappoesterin tai esteriseoksen valmistamiseksi
CA2096036A1 (en)	1994-02-21	Method for Stimulating Intracellular Synthesis of Glutathione Using Esters of L-2-Oxothiazolidine-4-Carboxylate
EP0390577A3 (en)	1991-02-27	Purification and preparation processes for methyl methacrylate
FR2736549B1 (fr)	1997-10-10	Esters d'acides gras iodes, acides gras iodes et leurs derives, obtenus par iodohydrination faisant intervenir des derives alkylsilyles avec des iodures alcalins et leurs activites pharmacologiques
CA2040925A1 (en)	1991-10-25	Method of purifying polyunsaturated aliphatic compounds
IE821911L (en)	1983-02-10	Preparing insulin derivatives
KR970009594B1 (en)	1997-06-14	PROCESS FOR PRODUCING Ñß- L - ASPARTYL - L - PHENYLALANINE METHYL ESTER
NZ333574A (en)	2000-03-27	Water miscible erythromycin solutions
CA2240201A1 (en)	1997-07-17	Process for the preparation of felodipine
HK131993A (en)	1993-12-10	Preparation of non-racemic furo[3,4-c]pyridine derivatives
YU48643B (sh)	1999-06-15	Nove 3,3'-ditiobis(propionske kiseline) i njihovi estri
DK0482344T3 (da)	1994-08-15	Fremgangsmåde til fremstilling af uforsæbelige forbindelser
EP0402322A3 (en)	1991-01-02	Process for the production of r(+)-aminocarnitine and s(-)-amino-carnitine
EP0240431A3 (en)	1989-04-05	Process for the preparation of ethylenic carbonyl compounds
JPS5395958A (en)	1978-08-22	Prostaglandin analogues and process for their preparation
AU590439B2 (en)	1989-11-02	Process for producing alpha-L-aspartyl-L-phenylalanine methyl ester having an improved solubility
KR860008117A (ko)	1986-11-12	비닐사이클로프로판 카복실산 에스테르의 제조방법
ATE200776T1 (de)	2001-05-15	Verfahren zur herstellung von 2,4,5-tribrompyrrol-3-carbonitril
JPS5212125A (en)	1977-01-29	Process for preparation of oligoester (meth)acrylate emulsion
HUP9802187A3 (en)	2001-08-28	Method of producing 3-pentenic acid esters by carbonylation of alkoxynutenes
CA2054419A1 (en)	1992-05-02	Process for producing 6-(3-dimethylaminopropionyl)forskolin
JPS5419950A (en)	1979-02-15	Synthetic method of methylenebisbenzophenone derivative
JPS5227715A (en)	1977-03-02	Process for preparation of gamma-halogeno-delta- unsaturated carboxylic acid ester and/or gamma-lactone derivatives
JPS5217447A (en)	1977-02-09	Process for preparation of trans-4- aminomethylcyclohexane-carboxylic acid ester
JPS53149965A (en)	1978-12-27	Novel lactone derivative and its preparation

Legal Events

Date	Code	Title	Description
1993-08-26	A201	Request for examination
1993-08-26	PA0109	Patent application	St.27 status event code: A-0-1-A10-A12-nap-PA0109
1993-08-26	PA0201	Request for examination	St.27 status event code: A-1-2-D10-D11-exm-PA0201
1993-08-26	R17-X000	Change to representative recorded	St.27 status event code: A-3-3-R10-R17-oth-X000
1994-03-14	PG1501	Laying open of application	St.27 status event code: A-1-1-Q10-Q12-nap-PG1501
1997-01-29	E902	Notification of reason for refusal
1997-01-29	PE0902	Notice of grounds for rejection	St.27 status event code: A-1-2-D10-D21-exm-PE0902
1997-03-20	P11-X000	Amendment of application requested	St.27 status event code: A-2-2-P10-P11-nap-X000
1997-03-20	P13-X000	Application amended	St.27 status event code: A-2-2-P10-P13-nap-X000
1997-05-20	G160	Decision to publish patent application
1997-06-14	PG1605	Publication of application before grant of patent	St.27 status event code: A-2-2-Q10-Q13-nap-PG1605
1997-09-02	E701	Decision to grant or registration of patent right
1997-09-02	PE0701	Decision of registration	St.27 status event code: A-1-2-D10-D22-exm-PE0701
1997-10-14	GRNT	Written decision to grant
1997-10-14	PR0701	Registration of establishment	St.27 status event code: A-2-4-F10-F11-exm-PR0701
1997-10-14	PR1002	Payment of registration fee	St.27 status event code: A-2-2-U10-U11-oth-PR1002 Fee payment year number: 1
1999-01-15	PN2301	Change of applicant	St.27 status event code: A-5-5-R10-R13-asn-PN2301 St.27 status event code: A-5-5-R10-R11-asn-PN2301
1999-01-29	PN2301	Change of applicant	St.27 status event code: A-5-5-R10-R13-asn-PN2301 St.27 status event code: A-5-5-R10-R11-asn-PN2301
1999-06-23	PN2301	Change of applicant	St.27 status event code: A-5-5-R10-R13-asn-PN2301 St.27 status event code: A-5-5-R10-R11-asn-PN2301
2000-04-28	PR1001	Payment of annual fee	St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 4
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2003-12-23	PN2301	Change of applicant	St.27 status event code: A-5-5-R10-R11-asn-PN2301
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2013-09-09	PC1903	Unpaid annual fee	St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 20121015
2017-09-12	P22-X000	Classification modified	St.27 status event code: A-4-4-P10-P22-nap-X000
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