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KR900701277A - 피임 시스템 및 방법 - Google Patents

피임 시스템 및 방법

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Publication number
KR900701277A
KR900701277A KR1019900701321A KR900701321A KR900701277A KR 900701277 A KR900701277 A KR 900701277A KR 1019900701321 A KR1019900701321 A KR 1019900701321A KR 900701321 A KR900701321 A KR 900701321A KR 900701277 A KR900701277 A KR 900701277A
Authority
KR
South Korea
Prior art keywords
progestin
contraception
estrogen compound
daily dose
delivery system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
KR1019900701321A
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English (en)
Other versions
KR0182283B1 (ko
Inventor
에이. 패스큘 사무엘
Original Assignee
에이. 패스큘 사무엘
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Application filed by 에이. 패스큘 사무엘 filed Critical 에이. 패스큘 사무엘
Publication of KR900701277A publication Critical patent/KR900701277A/ko
Application granted granted Critical
Publication of KR0182283B1 publication Critical patent/KR0182283B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Communication Control (AREA)
  • Control Of Steam Boilers And Waste-Gas Boilers (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Transplanting Machines (AREA)
  • Moving Of Heads (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

내용 없음

Description

피임 시스템 및 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (28)

  1. a)아기를 가질 수 있는 나이의 여성에게 월경 주기의 약 2-약 7일에 17-알파-에티닐 에스트라디올 약 0.01-약 0.04㎎ 범위의 에스트로젠 1일 활성량에 해당하는, 피임에 효과적인 성분인 에스트로젠 화합물만을 포함하는 제1조성물을 매일 투약하고, b)월경 주기의 28일 까지, 매일 피임에 효과적인 1일 투약량의 프로게스틴을 포함하는 최소한 하나의 제2조성물을 상기 여성에게 투약하는 것으로 구성되는 피임 방법.
  2. 제1항에 있어서, 제2조성물이 피임에 활성인 성분으로서 프로게스틴을 포함하는 피임 방법.
  3. 제1항에 있어서, 제2조성물이 피임에 효과적인 양의 에스트로젠 화합물 및 프로게스틴으로 구성되는 피임방법.
  4. 제1항에 있어서, 에스트로젠 화합물이 에티닐 에스트라디올인 피임방법.
  5. 제1항에 있어서, 에스트로젠 화합물이 메스트라놀인 피임방법.
  6. 제1항에 있어서, 에스트로젠 화합물이 17-베타-에스트라디올인 피임방법.
  7. 제1항에 있어서, 제2조성물이 약 0.5-약 1.0㎎의 1일 투약량인 노레틴드론을 포함하는 피임 방법.
  8. 제1항에 있어서, 프로게스틴이 D-노르제스트렐인 피임 방법.
  9. 제1항에 있어서, 프로게스틴이 D-17-베타아세톡시-13-베타-에틸-17-알파-에티닐-곤-4-엔-5-온 옥심인 피임 방법.
  10. 제1항에 있어서, 프로게스틴이 19-노르-17-하이드록시 프로게스테론 에스테르인 피임 방법.
  11. 제1항에 있어서, 에스트로젠 화합물이 에티닐 에스트라디올이고 프로게스틴이 노레틴드론인 피임 방법.
  12. 제1항에 있어서, 에스트로젠 화합물이 에스트라놀이고 프로게스틴이 D-노르제스트렐인 피임 방법.
  13. 제1항에 있어서, 모든 투약된 다음 조성물에서 에스트로젠 화합물의 1일 투약량이 실질적으로 동일하고, 프로게스틴의 1일 투약량이 계속적인 다음 조성물에서 더 증가된, 다수의 다음 조성물이 순서적으로 투약된 피임 방법
  14. 제13항에 있어서, 에스트로젠 화합물이 에티닐 에스트라디올이고 프로게스틴이 노레틴드론인 피임 방법.
  15. 제14항에 있어서, 에티닐 에스트라디올의 1일 투약량이 약 0.035㎎인 피임 방법.
  16. 제1항에 있어서, 에스트로젠 화합물의 1일 투약량이 모든 다음 조성물에서 실질적으로 동일하고, 연속적 인 다음 조성물내 프로게스틴의 1일 투약량이 처음에 투약된 프로게스틴 1일 투약량보다 증가되고 그리고 처음 에 투약된 프로게스틴 1일 투약량까지 감소된, 다수의 다옴 조성물을 차례로 투약시키는 피임 방법.
  17. 제16항에 있어서, 에티닐 에스트라디올의 1일 투약량이 0.035㎎인 피임 방법.
  18. 실질적으로 피임에 효과적인 동일 1일 투약량의 에스트로젠 화합물을 포함하는, 최소한 4개의 초기 투약 단위: 피임에 효과적인 1일 투약량의 프로게스틴을 포함하는 21개의 다음 투약 단위로 구성되고, 경구 투약하는 최소한 24개의 개별 1일 투약 단위로 구성되는 약제 딜리버리 시스템.
  19. 제18항에 있어서, 21개의 다음 투약 단위가 각각 실질적으로 동일한 1일 투약량의 프로게스틴율 포함하는 약제 딜리버리 시스템.
  20. 제18항에 있어서, 21개외 다음 투약 단위가 각각 실질적으로 동일한 1일 투약량의 에스트로젠 화합물 및 프로게스텐을 포함하는 약제 딜리버리 시스템.
  21. 제18항에 있어서, 21개의 다음 투약 단위가 피임에 효과적인 1일 투약량의 에스트로젠 화함물 및 프로게스틴을 포함하는 17개 투약 단위의 재1그룹 및 피임에 효과적인 1일 투약량의 프로게스틴 및 에스트로젠 화합물을 포함하는 11개 투약 단위의 제2그룹으로 구성되는 약제 딜리버리 시스텔.
  22. 제18항에 있어서, 연속적으로 투약된 그룹을 구성하는 투약단위에서 에스트로젠 화함물 대 프로게스틴의 중량비가 다른다는 것을 전제로, 각 그룹이 개별적으로 실질적으로 동일한 중량비로 존재하는 프로게스틴 및 에스트로젠 화합물의 피임에 효과적인 1일 투약 단위로 구성되고, 다음 복용 단위가 약7개 복용 단위의 세개의 연속 그룹으로 구성되는 약제 딜리버리 시스템.
  23. 제22항에 있어서, 에스트로젠 화합물 대 프로게스틴의 중량비가 투약 단위의 제1및 제3연속 그룹에서 실질적으로 동일한 약제 딜리버리 시스템.
  24. 제18항에 있어서, 초기 투약 단위에 존재하는 에스트로젠 화합물이 에티닐 에스트라디올인 약제 딜리버리 시스템.
  25. 제l8항에 있어서, 초기 투약 단위에 존재하는 에스트로젠 화합물에 메스트라놀인 약재 딜리버리 시스템.
  26. 제18항에 있어서, 초기 투약 단위에 존재하는 에스트로젠 화합물에 17-베타-에스트라디올인 약제 딜리버리 시스템.
  27. 제18항에 있어서, 프로게스틴이 노레틴드론인 약제 딜리버리 시스템.
  28. 제18항에 있어서, 프로게스틴이 D-노르제스트렐인 약제 딜리버리 시스템.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900701321A 1988-10-20 1989-10-19 경구 투약하는 최소한 25개의 개별1일 투약단위를 포함하는 피임약 Expired - Lifetime KR0182283B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US260,447 1981-05-04
US260.447 1988-10-20
US07/260,447 US4921843A (en) 1988-10-20 1988-10-20 Contraception system and method
PCT/US1989/004697 WO1990004330A1 (en) 1988-10-20 1989-10-19 Contraception system and method

Publications (2)

Publication Number Publication Date
KR900701277A true KR900701277A (ko) 1990-12-01
KR0182283B1 KR0182283B1 (ko) 1999-05-01

Family

ID=22989203

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900701321A Expired - Lifetime KR0182283B1 (ko) 1988-10-20 1989-10-19 경구 투약하는 최소한 25개의 개별1일 투약단위를 포함하는 피임약

Country Status (15)

Country Link
US (1) US4921843A (ko)
EP (1) EP0397823B1 (ko)
JP (1) JP3001216B2 (ko)
KR (1) KR0182283B1 (ko)
AT (1) ATE175353T1 (ko)
AU (1) AU620940B2 (ko)
CA (1) CA2001144C (ko)
DE (1) DE68928897T2 (ko)
FI (1) FI103951B (ko)
HU (2) HUT51899A (ko)
IL (1) IL92069A0 (ko)
NZ (1) NZ231091A (ko)
PT (1) PT92069B (ko)
WO (1) WO1990004330A1 (ko)
ZA (1) ZA897977B (ko)

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Also Published As

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EP0397823A4 (en) 1991-04-03
HUT51899A (en) 1990-06-28
CA2001144A1 (en) 1990-04-20
FI903106A0 (fi) 1990-06-20
EP0397823A1 (en) 1990-11-22
FI103951B1 (fi) 1999-10-29
PT92069A (pt) 1990-04-30
CA2001144C (en) 1999-07-20
WO1990004330A1 (en) 1990-05-03
JPH03502932A (ja) 1991-07-04
AU620940B2 (en) 1992-02-27
JP3001216B2 (ja) 2000-01-24
NZ231091A (en) 1995-12-21
DE68928897T2 (de) 1999-07-29
ATE175353T1 (de) 1999-01-15
DE68928897D1 (de) 1999-02-18
KR0182283B1 (ko) 1999-05-01
PT92069B (pt) 1995-06-30
EP0397823B1 (en) 1999-01-07
ZA897977B (en) 1990-07-25
FI103951B (fi) 1999-10-29
AU4497089A (en) 1990-05-14
US4921843A (en) 1990-05-01
HU211931A9 (en) 1996-01-29
IL92069A0 (en) 1990-07-12

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