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KR880004810A - 소화성 궤양 치료제 - Google Patents

소화성 궤양 치료제 Download PDF

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Publication number
KR880004810A
KR880004810A KR870011129A KR870011129A KR880004810A KR 880004810 A KR880004810 A KR 880004810A KR 870011129 A KR870011129 A KR 870011129A KR 870011129 A KR870011129 A KR 870011129A KR 880004810 A KR880004810 A KR 880004810A
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KR
South Korea
Prior art keywords
peptic ulcer
formula
compound
therapeutic agent
oxohexyl
Prior art date
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Application number
KR870011129A
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English (en)
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KR950007101B1 (ko
Inventor
마사오 사꾸라이
마사요시 고또
토시쬬 타나까
Original Assignee
호르스트 바에쉐
훽스트 제펜 리미티드
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Publication of KR880004810A publication Critical patent/KR880004810A/ko
Application granted granted Critical
Publication of KR950007101B1 publication Critical patent/KR950007101B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

내용 없음

Description

소화성 궤양 치료제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 유효량의 하기 일반식(Ⅰ)의 화합물 하나 이상 및 약제학적으로 허용되는 담체 또는 부형제로 이루어짐을 특징으로 하는 소화성 궤양 치료제.
    상기식에서 R1은 4-옥소펜틸 또는 5-옥소헥실이고, R2는 메틸 또는 에틸이며, R3는 C2-C4-알킬이다.
  2. 제1항에 있어서, 일반식(Ⅰ)에서의 R1이 5-옥소헥실이고, R2가 메틸이며, R3가 프로필임을 특징으로 하는 치료제
  3. 제1항 또는 제2항에서 정의한 일반식(Ⅰ)의 화합물 하나 이상의 유효량을 생리학적으로 허용되는 담체 또는 부형제와 함께 적합한 투여 형태로 제조함을 특징으로 하여, 소화성 궤양 치료제를 제조하는 방법.
  4. 소화성 궤양을 앓고 있는 사람에게 제1항 또는 제2항에서 정의한 일반식(Ⅰ)의 화합물 하나 이상의 유효량을 약제학적 조성물의 형태로 투여함을 특징으로 하여 소화성 궤양을 앓고 있는 사람을 치료하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870011129A 1986-10-06 1987-10-06 소화성 궤양 치료제 Expired - Fee Related KR950007101B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP236078/86 1986-10-06
JP23607886 1986-10-06
JP236078 1986-10-06

Publications (2)

Publication Number Publication Date
KR880004810A true KR880004810A (ko) 1988-06-27
KR950007101B1 KR950007101B1 (ko) 1995-06-30

Family

ID=16995393

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870011129A Expired - Fee Related KR950007101B1 (ko) 1986-10-06 1987-10-06 소화성 궤양 치료제

Country Status (16)

Country Link
US (1) US4845102A (ko)
EP (1) EP0266559B1 (ko)
JP (1) JPS63225317A (ko)
KR (1) KR950007101B1 (ko)
AT (1) ATE75399T1 (ko)
AU (1) AU595379B2 (ko)
CA (1) CA1297021C (ko)
DE (1) DE3778642D1 (ko)
DK (1) DK169305B1 (ko)
ES (1) ES2032797T3 (ko)
GR (1) GR3004848T3 (ko)
HU (1) HU200098B (ko)
IE (1) IE60863B1 (ko)
IL (1) IL84096A (ko)
PT (1) PT85866B (ko)
ZA (1) ZA877454B (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2661666B2 (ja) * 1988-02-19 1997-10-08 ヘキスト薬品工業株式会社 抗消化性潰瘍剤
DD298051A5 (de) * 1989-08-16 1992-02-06 ��@���������@�������k�� Verfahren zur herstellung eines therapeutischen agens zur behandlung von verdauungskrankheiten
DE4025371A1 (de) * 1990-08-10 1992-02-13 Kali & Salz Ag Verfahren zur reinigung von elektrostatisch gewonnenem steinsalz
EP0570831A2 (de) * 1992-05-20 1993-11-24 Hoechst Aktiengesellschaft Verwendung von Xanthinderivaten zur Behandlung von Nervenschädigungen nach Unterbrechung der Blutzirkulation
US5780476A (en) * 1992-11-16 1998-07-14 Cell Therapeutics, Inc. Hydroxyl-containing xanthine compounds
US6693105B1 (en) 1992-11-16 2004-02-17 Cell Therapeutics, Inc. Hydroxyl-containing compounds
US20030207901A1 (en) * 1999-07-27 2003-11-06 Cell Therapeutics, Inc. Hydroxyl-containing compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2330742C2 (de) * 1973-06-16 1982-07-29 Hoechst Ag, 6000 Frankfurt 1-(Oxoalkyl)-3-methyl-7-alkylxanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
CH608236A5 (ko) * 1974-01-22 1978-12-29 Wuelfing J A Fa
CA1075690A (en) * 1974-12-13 1980-04-15 Hoechst Aktiengesellschaft Xanthine derivatives
US4511557A (en) * 1981-08-24 1985-04-16 Gauri Kailash Kumar Pharmaceutical composition
IT1200944B (it) * 1982-08-10 1989-01-27 Malesci Sas Derivati xantinici,procedimento per la loro preparazione,composizione farmaceutiche che il contengono e loro impiego terapeutico
US4636507A (en) * 1984-04-30 1987-01-13 Hoechst-Roussel Pharmaceuticals Inc. Host defense mechanism enhancement

Also Published As

Publication number Publication date
IE872656L (en) 1988-04-06
GR3004848T3 (ko) 1993-04-28
US4845102A (en) 1989-07-04
IL84096A0 (en) 1988-03-31
KR950007101B1 (ko) 1995-06-30
AU595379B2 (en) 1990-03-29
DK520787D0 (da) 1987-10-05
DK520787A (da) 1988-04-07
ES2032797T3 (es) 1993-03-01
HU200098B (en) 1990-04-28
JPS63225317A (ja) 1988-09-20
ATE75399T1 (de) 1992-05-15
EP0266559A2 (en) 1988-05-11
EP0266559B1 (en) 1992-04-29
AU7935887A (en) 1988-04-14
EP0266559A3 (en) 1990-06-06
DE3778642D1 (de) 1992-06-04
PT85866A (en) 1987-11-01
ZA877454B (en) 1988-05-25
DK169305B1 (da) 1994-10-10
IL84096A (en) 1991-07-18
HUT46214A (en) 1988-10-28
CA1297021C (en) 1992-03-10
IE60863B1 (en) 1994-08-24
PT85866B (pt) 1990-07-31

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