KR880004810A - 소화성 궤양 치료제 - Google Patents
소화성 궤양 치료제 Download PDFInfo
- Publication number
- KR880004810A KR880004810A KR870011129A KR870011129A KR880004810A KR 880004810 A KR880004810 A KR 880004810A KR 870011129 A KR870011129 A KR 870011129A KR 870011129 A KR870011129 A KR 870011129A KR 880004810 A KR880004810 A KR 880004810A
- Authority
- KR
- South Korea
- Prior art keywords
- peptic ulcer
- formula
- compound
- therapeutic agent
- oxohexyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
Claims (4)
- 유효량의 하기 일반식(Ⅰ)의 화합물 하나 이상 및 약제학적으로 허용되는 담체 또는 부형제로 이루어짐을 특징으로 하는 소화성 궤양 치료제.상기식에서 R1은 4-옥소펜틸 또는 5-옥소헥실이고, R2는 메틸 또는 에틸이며, R3는 C2-C4-알킬이다.
- 제1항에 있어서, 일반식(Ⅰ)에서의 R1이 5-옥소헥실이고, R2가 메틸이며, R3가 프로필임을 특징으로 하는 치료제
- 제1항 또는 제2항에서 정의한 일반식(Ⅰ)의 화합물 하나 이상의 유효량을 생리학적으로 허용되는 담체 또는 부형제와 함께 적합한 투여 형태로 제조함을 특징으로 하여, 소화성 궤양 치료제를 제조하는 방법.
- 소화성 궤양을 앓고 있는 사람에게 제1항 또는 제2항에서 정의한 일반식(Ⅰ)의 화합물 하나 이상의 유효량을 약제학적 조성물의 형태로 투여함을 특징으로 하여 소화성 궤양을 앓고 있는 사람을 치료하는 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP236078/86 | 1986-10-06 | ||
| JP23607886 | 1986-10-06 | ||
| JP236078 | 1986-10-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR880004810A true KR880004810A (ko) | 1988-06-27 |
| KR950007101B1 KR950007101B1 (ko) | 1995-06-30 |
Family
ID=16995393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019870011129A Expired - Fee Related KR950007101B1 (ko) | 1986-10-06 | 1987-10-06 | 소화성 궤양 치료제 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4845102A (ko) |
| EP (1) | EP0266559B1 (ko) |
| JP (1) | JPS63225317A (ko) |
| KR (1) | KR950007101B1 (ko) |
| AT (1) | ATE75399T1 (ko) |
| AU (1) | AU595379B2 (ko) |
| CA (1) | CA1297021C (ko) |
| DE (1) | DE3778642D1 (ko) |
| DK (1) | DK169305B1 (ko) |
| ES (1) | ES2032797T3 (ko) |
| GR (1) | GR3004848T3 (ko) |
| HU (1) | HU200098B (ko) |
| IE (1) | IE60863B1 (ko) |
| IL (1) | IL84096A (ko) |
| PT (1) | PT85866B (ko) |
| ZA (1) | ZA877454B (ko) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2661666B2 (ja) * | 1988-02-19 | 1997-10-08 | ヘキスト薬品工業株式会社 | 抗消化性潰瘍剤 |
| DD298051A5 (de) * | 1989-08-16 | 1992-02-06 | ��@���������@�������k�� | Verfahren zur herstellung eines therapeutischen agens zur behandlung von verdauungskrankheiten |
| DE4025371A1 (de) * | 1990-08-10 | 1992-02-13 | Kali & Salz Ag | Verfahren zur reinigung von elektrostatisch gewonnenem steinsalz |
| EP0570831A2 (de) * | 1992-05-20 | 1993-11-24 | Hoechst Aktiengesellschaft | Verwendung von Xanthinderivaten zur Behandlung von Nervenschädigungen nach Unterbrechung der Blutzirkulation |
| US5780476A (en) * | 1992-11-16 | 1998-07-14 | Cell Therapeutics, Inc. | Hydroxyl-containing xanthine compounds |
| US6693105B1 (en) | 1992-11-16 | 2004-02-17 | Cell Therapeutics, Inc. | Hydroxyl-containing compounds |
| US20030207901A1 (en) * | 1999-07-27 | 2003-11-06 | Cell Therapeutics, Inc. | Hydroxyl-containing compounds |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2330742C2 (de) * | 1973-06-16 | 1982-07-29 | Hoechst Ag, 6000 Frankfurt | 1-(Oxoalkyl)-3-methyl-7-alkylxanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| CH608236A5 (ko) * | 1974-01-22 | 1978-12-29 | Wuelfing J A Fa | |
| CA1075690A (en) * | 1974-12-13 | 1980-04-15 | Hoechst Aktiengesellschaft | Xanthine derivatives |
| US4511557A (en) * | 1981-08-24 | 1985-04-16 | Gauri Kailash Kumar | Pharmaceutical composition |
| IT1200944B (it) * | 1982-08-10 | 1989-01-27 | Malesci Sas | Derivati xantinici,procedimento per la loro preparazione,composizione farmaceutiche che il contengono e loro impiego terapeutico |
| US4636507A (en) * | 1984-04-30 | 1987-01-13 | Hoechst-Roussel Pharmaceuticals Inc. | Host defense mechanism enhancement |
-
1987
- 1987-09-24 JP JP62237540A patent/JPS63225317A/ja active Pending
- 1987-10-01 DE DE8787114328T patent/DE3778642D1/de not_active Expired - Lifetime
- 1987-10-01 AT AT87114328T patent/ATE75399T1/de active
- 1987-10-01 ES ES198787114328T patent/ES2032797T3/es not_active Expired - Lifetime
- 1987-10-01 EP EP87114328A patent/EP0266559B1/en not_active Expired - Lifetime
- 1987-10-02 US US07/103,816 patent/US4845102A/en not_active Expired - Fee Related
- 1987-10-05 HU HU874468A patent/HU200098B/hu not_active IP Right Cessation
- 1987-10-05 IE IE265687A patent/IE60863B1/en not_active IP Right Cessation
- 1987-10-05 ZA ZA877454A patent/ZA877454B/xx unknown
- 1987-10-05 IL IL84096A patent/IL84096A/xx not_active IP Right Cessation
- 1987-10-05 CA CA000548615A patent/CA1297021C/en not_active Expired - Lifetime
- 1987-10-05 DK DK520787A patent/DK169305B1/da not_active IP Right Cessation
- 1987-10-05 AU AU79358/87A patent/AU595379B2/en not_active Ceased
- 1987-10-06 KR KR1019870011129A patent/KR950007101B1/ko not_active Expired - Fee Related
- 1987-10-06 PT PT85866A patent/PT85866B/pt not_active IP Right Cessation
-
1992
- 1992-06-05 GR GR920401188T patent/GR3004848T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE872656L (en) | 1988-04-06 |
| GR3004848T3 (ko) | 1993-04-28 |
| US4845102A (en) | 1989-07-04 |
| IL84096A0 (en) | 1988-03-31 |
| KR950007101B1 (ko) | 1995-06-30 |
| AU595379B2 (en) | 1990-03-29 |
| DK520787D0 (da) | 1987-10-05 |
| DK520787A (da) | 1988-04-07 |
| ES2032797T3 (es) | 1993-03-01 |
| HU200098B (en) | 1990-04-28 |
| JPS63225317A (ja) | 1988-09-20 |
| ATE75399T1 (de) | 1992-05-15 |
| EP0266559A2 (en) | 1988-05-11 |
| EP0266559B1 (en) | 1992-04-29 |
| AU7935887A (en) | 1988-04-14 |
| EP0266559A3 (en) | 1990-06-06 |
| DE3778642D1 (de) | 1992-06-04 |
| PT85866A (en) | 1987-11-01 |
| ZA877454B (en) | 1988-05-25 |
| DK169305B1 (da) | 1994-10-10 |
| IL84096A (en) | 1991-07-18 |
| HUT46214A (en) | 1988-10-28 |
| CA1297021C (en) | 1992-03-10 |
| IE60863B1 (en) | 1994-08-24 |
| PT85866B (pt) | 1990-07-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
St.27 status event code: A-0-1-A10-A12-nap-PA0109 |
|
| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| A201 | Request for examination | ||
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| G160 | Decision to publish patent application | ||
| PG1605 | Publication of application before grant of patent |
St.27 status event code: A-2-2-Q10-Q13-nap-PG1605 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
|
| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U11-oth-PR1002 Fee payment year number: 1 |
|
| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 19980701 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE |
|
| PC1903 | Unpaid annual fee |
St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 19980701 |
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| P22-X000 | Classification modified |
St.27 status event code: A-4-4-P10-P22-nap-X000 |