KR860005814A - 1,6-나프티리딘-2(1h)-온 및 그의 제조방법 - Google Patents

1,6-나프티리딘-2(1h)-온 및 그의 제조방법

Info

Publication number: KR860005814A
Authority: KR; South Korea
Prior art keywords: naphthyridin; preparation
Prior art date: 1985-01-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

KR1019850010151A

Other languages

English (en)

Other versions

KR900004213B1 (ko

Inventor

요어 레셔어 죠오지

싱 발데브

Original Assignee

스터어링 드럭그 인코포레이팃드

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-01-14

Filing date

1985-12-31

Publication date

1986-08-13

1985-12-31 Application filed by 스터어링 드럭그 인코포레이팃드 filed Critical 스터어링 드럭그 인코포레이팃드

1986-08-13 Publication of KR860005814A publication Critical patent/KR860005814A/ko

1990-06-18 Application granted granted Critical

1990-06-18 Publication of KR900004213B1 publication Critical patent/KR900004213B1/ko

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

KR1019850010151A 1985-01-14 1985-12-31 1,6-나프티리딘-2(1h)-온 및 그의 제조방법 Expired KR900004213B1 (ko)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US691802		1985-01-14
US06/691,802 US4567186A (en)	1985-01-14	1985-01-14	5-Heteryl-1,6-naphthyridin-2(1H)-ones, cardiotonic use thereof and intermediates therefor

Publications (2)

Publication Number	Publication Date
KR860005814A true KR860005814A (ko)	1986-08-13
KR900004213B1 KR900004213B1 (ko)	1990-06-18

Family

ID=24778039

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1019850010151A Expired KR900004213B1 (ko)	1985-01-14	1985-12-31	1,6-나프티리딘-2(1h)-온 및 그의 제조방법

Country Status (8)

Country	Link
US (1)	US4567186A (ko)
EP (1)	EP0191298A3 (ko)
JP (1)	JPS61210086A (ko)
KR (1)	KR900004213B1 (ko)
AU (1)	AU585565B2 (ko)
DK (1)	DK13786A (ko)
GR (1)	GR860075B (ko)
NZ (1)	NZ214788A (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2686612A (en) *	1950-06-13	1954-08-17	Curlee Machinery Company Inc	Dispensing machine
US4853395A (en) *	1983-04-29	1989-08-01	Merrell Dow Pharmaceuticals Inc.	Certain 3-carboxylate or 3-carbamyl-5-acyl-2-(1H)-pyridinones having cardiotonic properties
US4650806A (en) *	1985-01-14	1987-03-17	Sterling Drug Inc.	Cardiotonic 5-(heterylcarbonyl)-pyridones
ZA9610741B (en)	1995-12-22	1997-06-24	Warner Lambert Co	4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en) *	1995-12-22	1997-06-27	Warner Lambert Co	2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610738B (en)	1995-12-22	1997-06-24	Warner Lambert Co	Subtype selective nmda receptor ligands and the use thereof
ZA9610745B (en) *	1995-12-22	1997-06-24	Warner Lambert Co	4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA985870B (en) *	1997-07-15	1999-01-27	Dainippon Pharmaceutical Co	5-substituted-3-oxadiazolyl-1, 6-naphthyridin-2(1H)-one derivatives
EP1429730A4 (en) *	2001-09-26	2010-06-16	Penwest Pharmaceuticals Compan	OPIOID FORMULATIONS WITH REDUCED ABUSE POTENTIAL
JP2006517976A (ja) *	2003-02-14	2006-08-03	スミスクライン・ビーチャム・コーポレイション	新規化合物
EP3484874B1 (en) *	2016-07-14	2020-04-29	Bristol-Myers Squibb Company	Monocyclic heteroaryl substituted compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4412077A (en) *	1982-03-15	1983-10-25	Sterling Drug Inc.	Process for preparing 5-(lower-alkanoyl)-6-(lower-alkyl)-2(1H)-pyridinone
US4415580A (en) *	1982-08-02	1983-11-15	Sterling Drug Inc.	Certain 2-(1H)-pyridinones cardiotonic compositions containing same and method of using same
US4532247A (en) *	1983-08-08	1985-07-30	Sterling Drug Inc.	5-(Hydroxyalkyl or alkanoyloxymethyl)-1,6-naphthyridin-2(1H)-one and cardiotonic use thereof
US4710507A (en) *	1983-12-22	1987-12-01	Pfizer Inc.	Quinolone inotropic agents
US4560691A (en) *	1984-07-13	1985-12-24	Sterling Drug Inc.	5-(Phenyl)-1,6-naphthyridin-2(1H)-ones, their cardiotonic use and preparation
NZ214837A (en) *	1985-01-28	1988-10-28	Sterling Drug Inc	5-substituted 1,6 naphthyridin-2(1h)-ones

1985
- 1985-01-14 US US06/691,802 patent/US4567186A/en not_active Expired - Fee Related
- 1985-12-31 KR KR1019850010151A patent/KR900004213B1/ko not_active Expired
1986
- 1986-01-07 AU AU51873/86A patent/AU585565B2/en not_active Ceased
- 1986-01-10 EP EP86100295A patent/EP0191298A3/en not_active Ceased
- 1986-01-10 NZ NZ214788A patent/NZ214788A/xx unknown
- 1986-01-13 DK DK13786A patent/DK13786A/da not_active Application Discontinuation
- 1986-01-14 JP JP61006190A patent/JPS61210086A/ja active Pending
- 1986-01-14 GR GR860075A patent/GR860075B/el unknown

Also Published As

Publication number	Publication date
AU5187386A (en)	1986-07-17
DK13786A (da)	1986-07-15
AU585565B2 (en)	1989-06-22
EP0191298A2 (en)	1986-08-20
US4567186A (en)	1986-01-28
JPS61210086A (ja)	1986-09-18
EP0191298A3 (en)	1986-12-03
GR860075B (en)	1986-05-14
DK13786D0 (da)	1986-01-13
KR900004213B1 (ko)	1990-06-18
NZ214788A (en)	1988-09-29

Publication	Publication Date	Title
NZ220853A (en)	1989-09-27	Imidazopyridine, intermediates and preparation
NL300014I1 (nl)	2000-10-02	Chinolinederivaten en bereidingsprocessen hiervoor.
FI870582A7 (fi)	1987-08-14	Aminouretaaneja, niiden valmistusmenetelmä ja niiden käyttö
FI870439A0 (fi)	1987-02-02	Apparat foer framstaellning av kapslar med flera kamrar.
DE3675824D1 (de)	1991-01-10	Antianaphylaktische und antibronchospastische n-benzhydrylcycloalkylalkananilide.
TR22532A (tr)	1987-10-12	Piridazinon tuerevleri,bunlarin hazirlanmasi ve ensektisid,akarisid nematisid fungisid bilesikleri
DE3571437D1 (de)	1989-08-17	Pyrazolopyridine derivatives
KR860005810A (ko)	1986-08-13	4h-1-벤조피란-4-온 및 그 제조방법
KR860005814A (ko)	1986-08-13	1,6-나프티리딘-2(1h)-온 및 그의 제조방법
FI860556A7 (fi)	1986-08-16	Uusia 1,8-naftyridiinijohdannaisia ja niiden valmistusmenetelmä.
IL81042A0 (en)	1987-03-31	Pyridine derivatives and n-oxides thereof,processes for their preparation and the use thereof as intermediates
MA20660A1 (fr)	1986-12-31	Derives de nitrofuranne, leur preparation et leur application
DK615086D0 (da)	1986-12-18	5,6-dialkoxy-4-imino-2(1h)quinazolinderivater
IT1204813B (it)	1989-03-10	Gruppo cilindo-stantuffo
FR2568879B1 (fr)	1986-12-12	Imidazo(1,2-a)quinolines, leur preparation et leur application en therapeutique
FR2591600B1 (fr)	1990-05-11	Derives de la glucosylmoranoline et leur preparation
IT1187681B (it)	1987-12-23	Metodo per la preparazione di 3,4-epossibutirrati alchilici
KR870004977A (ko)	1987-06-02	2,2'-바이-1h-이미다졸 및 그의 제조방법
FI864566A7 (fi)	1987-05-20	Nitroantrasykliinit, niiden valmistusmenetelmä ja niiden käyttö.
KR920002008A (ko)	1992-01-30	1,2,4-트리아조로[1,5-c] 피리미딘 및 이의 제조방법
IT1213496B (it)	1989-12-20	Trimetilsililcarbammati e procedimento per la loro preparazione
NZ214837A (en)	1988-10-28	5-substituted 1,6 naphthyridin-2(1h)-ones
KR880700810A (ko)	1988-04-12	2'-데옥시-5-트리플루오로메틸우리딘 유도체 및 그의 제조방법
BR8502633A (pt)	1987-01-06	Metodo de preparacao de 2,3,5,6-tetracloropiridina
ZA86320B (en)	1986-08-27	1,6-naphthyridin-2(1h)-ones having cardiotonic activity and preparation

Legal Events

Date	Code	Title	Description
1985-12-31	PA0109	Patent application	St.27 status event code: A-0-1-A10-A12-nap-PA0109
1985-12-31	R17-X000	Change to representative recorded	St.27 status event code: A-3-3-R10-R17-oth-X000
1986-01-24	P11-X000	Amendment of application requested	St.27 status event code: A-2-2-P10-P11-nap-X000
1986-01-24	P13-X000	Application amended	St.27 status event code: A-2-2-P10-P13-nap-X000
1986-08-13	PG1501	Laying open of application	St.27 status event code: A-1-1-Q10-Q12-nap-PG1501
1987-09-07	A201	Request for examination
1987-09-07	P11-X000	Amendment of application requested	St.27 status event code: A-2-2-P10-P11-nap-X000
1987-09-07	P13-X000	Application amended	St.27 status event code: A-2-2-P10-P13-nap-X000
1987-09-07	PA0201	Request for examination	St.27 status event code: A-1-2-D10-D11-exm-PA0201
1990-02-14	E902	Notification of reason for refusal
1990-02-14	PE0902	Notice of grounds for rejection	St.27 status event code: A-1-2-D10-D21-exm-PE0902
1990-04-12	T11-X000	Administrative time limit extension requested	St.27 status event code: U-3-3-T10-T11-oth-X000
1990-05-14	P11-X000	Amendment of application requested	St.27 status event code: A-2-2-P10-P11-nap-X000
1990-05-14	P13-X000	Application amended	St.27 status event code: A-2-2-P10-P13-nap-X000
1990-05-22	G160	Decision to publish patent application
1990-06-18	PG1605	Publication of application before grant of patent	St.27 status event code: A-2-2-Q10-Q13-nap-PG1605
1990-08-31	E701	Decision to grant or registration of patent right
1990-08-31	PE0701	Decision of registration	St.27 status event code: A-1-2-D10-D22-exm-PE0701
1990-10-19	GRNT	Written decision to grant
1990-10-19	PR0701	Registration of establishment	St.27 status event code: A-2-4-F10-F11-exm-PR0701
1990-10-19	PR1002	Payment of registration fee	St.27 status event code: A-2-2-U10-U11-oth-PR1002 Fee payment year number: 1
1993-06-19	LAPS	Lapse due to unpaid annual fee
1993-06-19	PC1903	Unpaid annual fee	St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 19930619 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE
1994-10-08	PC1903	Unpaid annual fee	St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 19930619