KR101352802B1 - Apparatus for health diagnosing inserted into human body and method for health diagnosing using the apparatus - Google Patents

Abstract

The present invention relates to a medical diagnostic apparatus for human body insertion and a medical diagnostic method using the same. The medical diagnostic apparatus for inserting a human body according to an embodiment of the present invention includes an insertion part having a cylindrical shape, a blood flow measuring part for measuring a blood flow rate of blood flowing through a measuring point, and an outer high for fixing the insertion part inside the human body. Including the government, the blood flow measurement unit includes an optical connecting line for receiving the laser light from the outside and a variable focus lens for adjusting the incident angle and the focal length of the laser light. According to the present invention, by easily measuring the blood flow rate, oxygen saturation, blood volume, etc. of the blood flowing to the measurement point has the advantage that it is possible to quickly and easily check the health state of the subject.

Description

Medical diagnostic device for human body insertion and medical diagnostic method using the same {APPARATUS FOR HEALTH DIAGNOSING INSERTED INTO HUMAN BODY AND METHOD FOR HEALTH DIAGNOSING USING THE APPARATUS}

The present invention relates to a medical diagnostic apparatus for human body insertion and a medical diagnostic method using the same.

Recently, as the public's interest in health increases, various methods and devices for diagnosing various diseases and symptoms have been developed. In particular, various methods for diagnosing sexual dysfunction in women due to environmental hormones and stress have been developed.

The exciting period of female sexual response is not easily distinguished from the period of desire until physiological changes occur in the vagina and clitoris as well as other sexual organs. Sexual excitement and pleasure are accompanied by a combination of vascular and neuromuscular events that lead to hyperemia of the clitoris, labia and vaginal walls, increased vaginal lubrication and dilation of the vaginal lumen.

Vaginal hyperemia can cause leakage and this process causes increased vaginal lubrication. Leakage allows plasma to flow through the epithelium and onto the vaginal surface, the driving force for which is increased blood flow on the vaginal capillaries during the excited state.

In addition, hyperemia results in an increase in vaginal length and lumen diameter, especially the lumen diameter at the distal 2/3 point of the vaginal canal. Vaginal lumen dilation is due to a combination of smooth muscle relaxation in the vaginal wall and skeletal muscle relaxation in the pelvic floor. Some sexual pain disorders, such as vaginal spasms, are at least in part due to inadequate relaxation that interferes with vaginal expansion.

The present invention is inserted into the human body to easily check the blood flow rate, oxygen saturation, blood volume, etc. of the blood flowing to the measurement point, and the human diagnostic device for human insertion and health can be quickly and easily check the health status of the subject It is an object to provide a diagnostic method.

The objects of the present invention are not limited to the above-mentioned objects, and other objects and advantages of the present invention which are not mentioned can be understood by the following description and more clearly understood by the embodiments of the present invention. It will also be readily apparent that the objects and advantages of the invention may be realized and attained by means of the instrumentalities and combinations particularly pointed out in the appended claims.

In accordance with an aspect of the present invention, there is provided a medical diagnostic apparatus for inserting a human body, comprising: an insert having a cylindrical shape, a blood flow measuring unit for measuring a blood flow rate of blood flowing at a measuring point, and a fixing unit inside the human body Including an outer fixing portion, the blood flow measuring unit is characterized in that it comprises an optical connecting line for receiving the laser light from the outside and a variable focus lens for adjusting the incident angle and the focal length of the laser light.

In another aspect, the present invention provides a medical diagnostic method using a medical device for inserting a human body, the method comprising: receiving a laser light, adjusting a focal length and an incident angle of the laser light, irradiating the laser light to blood flowing at a measurement point And detecting the laser light reflected by the blood and measuring the frequency change of the detected laser light to determine the blood flow rate of the blood.

According to the present invention as described above, by easily measuring the blood flow rate, oxygen saturation, blood volume, etc. of the blood flowing to the measuring point there is an advantage that can be quickly and easily check the health state of the subject.

1 is a structural diagram of a medical examination device according to an embodiment of the present invention.
2 is a side cross-sectional view of a medical examination apparatus according to an embodiment of the present invention.
3 is a bottom cross-sectional view of a medical examination apparatus according to an embodiment of the present invention.
4 is a cross-sectional view of the rubber packing at each position of the medical examination device according to an embodiment of the present invention.
5 is a cross-sectional view illustrating a variable balloon type fixing unit of a medical examination apparatus according to an embodiment of the present invention.
6 is a cross-sectional view illustrating a variable balloon type fixing unit of a medical examination apparatus according to another exemplary embodiment of the present invention.
FIG. 7 is a cross-sectional view illustrating a variable balloon type fixing unit of a medical examination apparatus according to another exemplary embodiment of the present invention.
8 is a cross-sectional view for explaining a variable balloon type fixing part of a medical examination apparatus according to another embodiment of the present invention.
9 is a cross-sectional view for explaining a bellows-type fixing part of a medical examination apparatus according to an embodiment of the present invention.
10 is a cross-sectional view for describing a bellows-type fixing part of a medical examination apparatus according to another exemplary embodiment of the present invention.
11 is a view for explaining the operating principle of the laser Doppler interferometer used in one embodiment of the present invention.
12 is a flow chart of a medical examination method according to an embodiment of the present invention.

The above and other objects, features, and advantages of the present invention will become more apparent by describing in detail exemplary embodiments thereof with reference to the attached drawings, which are not intended to limit the scope of the present invention. In the following description, well-known functions or constructions are not described in detail since they would obscure the invention in unnecessary detail. Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. In the drawings, the same reference numerals are used to denote the same or similar elements.

1 is a structural diagram of a medical examination device according to an embodiment of the present invention.

The medical examination apparatus 102 according to the embodiment of the present invention includes an insertion unit 104, a blood flow measurement unit 106, an oxygen saturation measurement unit 108, a blood volume measurement unit 110, and an outer fixing unit 112. do.

Insertion portion 104 forms the appearance of the medical examination device 102, may have a shape that is easy to be inserted into the human body. For example, the insert 104 may have a cylindrical shape, such as a tampon. In addition, the insertion unit 104 may include a blood flow measuring unit 106, an oxygen saturation measuring unit 108, a blood volume measuring unit 110, and an outer fixing unit 112.

Blood flow measurement unit 106 measures the blood flow rate of the blood flowing to the measurement point in the human body to be measured by the medical examination device (102). In one embodiment of the present invention, the blood flow measurement unit 106 may include an optical connection line for receiving the laser light from the outside, and a variable focus lens for adjusting the incident angle and the focal length of the laser light. In this case, the inserting part 104 may include a transparent window to allow laser light to be radiated from the inside of the inserting part 104 to the outside. In another embodiment of the present invention, the blood flow measurement unit 106 may be a laser Doppler interferometer.

Oxygen saturation measuring unit 108 and the blood volume measuring unit 110 measures the oxygen saturation and the blood amount of the blood flowing to the measurement point inside the human body to be measured by the medical examination device 102, respectively. In one embodiment of the present invention, the oxygen saturation measuring unit 108 and the blood volume measuring unit 110 may be implemented as a separate or one module. In one embodiment of the present invention, the oxygen saturation measuring unit 108 or the blood volume measuring unit 110 is a light source unit for irradiating laser light to the blood, a photodetector for measuring the amount of laser light reflected from the blood, heat to the measuring point It may include a heat source for applying and a temperature measuring unit for measuring the temperature of the measuring point. At this time, the oxygen saturation level or blood amount of the blood may be determined using the amount of light measured by the photodetector.

In another embodiment of the present invention, the oxygen saturation measuring unit 108 or the blood volume measuring unit 110 includes two light source units for irradiating laser light of different wavelengths and two photodetectors for measuring the amount of laser light reflected from blood. It may include. In this case, the two photodetectors each measure an amount of laser light emitted from a light source unit positioned in a diagonal direction, and the heat source unit may exist at an intersection of diagonal lines connecting the two light source units and the two photodetectors.

The outer fixing part 112 serves to fix the inserting part 104 inside the human body. In one embodiment of the present invention, the outer fixing portion 112 may be a variable balloon type. At this time, the outer fixing portion 112 is installed on the side of the inserting portion 104, when air is injected may include a variable balloon for fixing the inserting portion 104 inside the human body by touching the inner wall inside the human body. . The inserting unit 104 may include an air hole for injecting air into the variable balloon and an air pressure measuring unit for measuring the air pressure inside the inserting unit 104.

In another embodiment of the present invention, the outer fixing part 112 may be a bellows type. In this case, the outer fixing part 112 may include two or more bellows, and the oxygen saturation measuring unit 108 or the blood volume measuring unit 110 may be included in the outer fixing unit 112. In addition, the outer fixing portion 112 may further include a wing for reducing the stimulus to the measuring point generated by the two or more bellows.

In one embodiment of the present invention, the inserting part 104 may further include an inner fixing part for fixing at least one of an optical connecting line, a pneumatic connecting line, and an electrical connecting line included in the inserting unit 104.

Hereinafter, the configuration and operation principle of the medical examination apparatus according to the present invention through the embodiment. The medical examination apparatus according to the present embodiment may be inserted into the human body, for example, inside the vagina of a woman, and measure a blood state of a corresponding measurement point.

2 is a side cross-sectional view of a medical examination apparatus according to an embodiment of the present invention.

Referring to FIG. 2, the medical diagnostic apparatus according to the exemplary embodiment may include an optical connecting line 202, a pneumatic connecting line 204, a partition wall 206, a rubber packing 208, an air hole 210, and an electrical connecting line. 212, electrical connection line 214, light source 216, temperature sensor 218, pressure sensor 220, variable focus lens 222, transparent window 224. The insert surrounding these elements may have a shape that is easy to be inserted into the human body, for example a cylindrical shape such as a tampon.

The optical connecting line 202 serves to supply the laser light for measuring blood flow rate from the outside to the inside of the medical examination device. An example of the optical connection line 202 may be an optical fiber, but is not limited thereto.

The pneumatic connection line 204 serves to supply air from the outside of the medical examination device to the inside to deliver air or pneumatic pressure to the outer fixture of the present invention, for example the variable balloon or bellows, which will be described later. This air may be delivered to the deformable balloon through the air hole 210 or directly to the bellows.

The partition wall 206 serves to fix the inner fixing part such as the rubber packing 208 inside the medical examination device.

The electrical connection line 212 serves to supply an electrical signal from the outside of the medical examination apparatus to the inside, and the electrical connection line 214 serves to send an electrical signal from the inside of the medical examination apparatus to the outside.

The light source 216 serves to irradiate laser light to measure oxygen saturation or blood volume of blood flowing at the measurement point. This irradiated laser light passes through the blood of the measuring point and part is reflected, and the reflected laser light is detected by the light detector 304 which will be described with reference to FIG. 3.

The temperature sensor 218 serves to measure the temperature of the measuring point. The medical examination apparatus may change the temperature of the measurement point through a heat source such as the heater 302 which will be described with reference to FIG. 3, wherein the temperature change of the measurement point is referred to by referring to the temperature measured by the temperature sensor 218. Decide

The pressure sensor 220 measures the air pressure inside the medical examination device. When the outer fixing part of the medical examination apparatus is a variable balloon type to be described later, the medical examination apparatus may be fixed to the measurement object by inflation with air being injected into the variable balloon. At this time, the amount of air injected into the variable balloon is adjusted by referring to the air pressure inside the health diagnosis apparatus measured by the pressure sensor 220. The air pressure inside the medical examination device is considered here to be similar or substantially the same as the air pressure inside the variable balloon.

The variable focus lens 222 may adjust the focus or incident angle of the laser light input through the optical connection line 202. In one embodiment of the invention the laser light is irradiated to the skin of the human body, the angle and distance irradiated to the point to be measured is important. Since the variable focus lens 222 may change the focal length in the optical axis or its vertical direction, more accurate measurement values may be obtained by adjusting the irradiation angle and distance of the laser light. As such, by adjusting the focus or angle of incidence of the laser light through the variable focus lens 222, the health diagnosis apparatus according to the present invention has an advantage of measuring blood flow in capillaries or small arteries, which is difficult to measure by the conventional diagnosis apparatus. The variable focus lens 222 also increases the resolution of the laser light.

Meanwhile, in one embodiment of the present invention, the end of the optical connecting line 202 is processed into an inclined cross section, or the optical connecting line 202 itself is used to achieve an incidence angle of laser light, for example, 30 to 60 degrees, for measuring blood flow. Tilting can be used.

Further, in one embodiment of the present invention, the blood flow measuring unit including the optical connecting line 202 and the variable focus lens 222 may be a laser Doppler interferometer. The laser Doppler interferometer is a speedometer that calculates the speed of an object by measuring a change in frequency caused by the Doppler effect after irradiating a laser light to a moving object such as blood flow. This measurement principle will be described in more detail with reference to FIG. 14.

As such, the laser light input through the optical connection line 202 and passed through the variable focus lens 222 may be irradiated to the measurement object through the transparent window 224. The transparent window 224 is for irradiating laser light to the outside and may be made of any material through which the laser light can pass.

3 is a bottom cross-sectional view of a medical examination apparatus according to an embodiment of the present invention.

The functions of the partition wall 306, the rubber packing 308, the electrical connection lines 310 and 312, the temperature sensor 316, the pressure sensor 318, and the transparent window 320 illustrated in FIG. 3 are the same as those described with reference to FIG. 2. Do.

Meanwhile, a light source 314, a light detector 304, and a heater 302 are provided at the lower portion of the medical examination apparatus as shown in FIG. 3. In an embodiment of the present invention, two light sources 314 and two photo detectors 304 are provided. The two light sources 314 irradiate measuring points with laser light of different wavelengths, for example, laser light having wavelengths of 660 nm and 910 nm.

The laser light thus irradiated is partially reflected from the blood of the measuring point. At this time, the two photodetectors 304 detect the laser light irradiated by the light source 314 in the diagonal direction, respectively. For example, the laser light irradiated by the light source (660 nm) at the bottom left in FIG. 3 is reflected by blood and detected by the photo detector 304 at the top right of FIG. As such, the photodetectors 304 detect laser light in a diagonal direction, respectively, to obtain more accurate measured values.

On the other hand, a heat source such as the heater 302 exists at the intersection of the diagonals connecting the two light sources 314 and the two photo detectors 304. The heater 302 serves to impart a stimulus condition for the measurement object by applying heat to the measurement point. For example, when the medical examination device of the present invention is inserted into a woman's vagina and aims to diagnose the sexual dysfunction of a woman, the heat applied by the heater 302 replaces the sexual stimulation applied to the woman's vagina. Play a role. By observing the change in blood caused by the stimulation by heat in this way, it is possible to diagnose whether or not the measurement target responds to the stimulus normally.

In addition, the temperature of the heater 302 may be appropriately adjusted by referring to the temperature of the measurement point measured by the temperature sensor 316.

In this way, the oxygen saturation and the blood volume of the blood at the measurement point may be determined using the light amount of the laser light detected through the photo detector 304. First, the oxygen saturation is determined by calculating the intensity ratio of light having two near infrared wavelengths (wavelength 1 and wavelength 2) and multiplying the experimentally obtained constant value.

Oxygen Saturation = Constant * (Intensity of detected light at wavelength 1 / Detected light intensity at wavelength 2)

The blood volume is also calculated as follows. First, the variation in light intensity (I _B / I _T ) of two near infrared wavelengths (wavelength 1, wavelength 2) region (700-1000 nm) is measured using the modified Beer-Lambert's law. Then, the concentration change of hemoglobin oxide (HbO ₂ ) and non-hemoglobin (Hb) is calculated as follows.

Hemoglobin oxidation = constant 1 * log (I _B / I _T ) _wavelength 1 + constant 2 * log (I _B / I _T ) _wavelength 2

Non-hemoglobin variation = constant 3 * log (I _B / I _T ) _wavelength 1 + constant 4 * log (I _B / I _T ) _wavelength 2

The constants 1,2,3,4 are calculated using the absorption coefficients of light per mole at wavelengths 1 and 2 of hemoglobin oxide and non-hemoglobin oxide.

The calculated changes in blood volume can be measured by adding the calculated changes in oxidized hemoglobin and non-oxidized hemoglobin.

Blood volume change = Oxidized hemoglobin change + Non-oxidized hemoglobin change

4 is a cross-sectional view of the rubber packing at each position of the medical examination device according to an embodiment of the present invention.

In one embodiment of the present invention, the inside of the medical examination device is provided with an inner fixing portion for fixing at least one of the optical connection line, pneumatic connection line, electrical connection line included in the insertion portion. In FIG. 4, a rubber packing 408 is used as the inner fixing part.

Referring to FIG. 4, an optical connection line 402, a pneumatic connection line 404, an electrical connection line 412, 414, and the like, which are inserted from the outside, exist in the medical examination apparatus. Rubber packing 408 is used to fix these lines. Lines fixed by the rubber packing at points ①, ②, and ③ indicated in the cross-sectional view of FIG. 4 are as shown below in FIG. 4, respectively. For example, optical connection line 402, pneumatic connection line 404, electrical connection lines 412 and 414 are all fixed at point ①, and only optical connection line 402 is fixed at point ③.

5 to 8 are cross-sectional views for explaining the variable balloon type fixing part of the medical examination device according to an embodiment of the present invention.

In order to obtain an accurate measurement by inserting the medical examination device according to the present invention inside the human body such as the vagina of a woman, it is necessary to be fixed after insertion into the human body. In one embodiment of the present invention, a variable balloon may be used for the external fixation.

Referring to FIG. 5, the variable balloon 512 may be mounted to surround the entire insertion portion of the medical examination device. Therefore, after the pneumatic pressure is injected through the air hole 510, the entire circumference of the insertion portion is swelled as shown in the lower figure of FIG.

Meanwhile, referring to FIG. 6, the variable balloons 602 and 608 may be mounted at both ends of the insert. In this case as well, after pneumatic pressure is injected through the air holes 602 and 606, both ends of the insert portion swell up as shown in the lower figure of FIG. 6 to fix the health diagnosis apparatus inside the human body.

In addition, the variable balloon 704 may be mounted in the transverse direction as shown in FIG. 7, or may be mounted in the longitudinal direction of the insert as shown in the variable balloons 804 and 808 of FIG. 8.

9 and 10 are cross-sectional views illustrating a bellows type fixing unit of a medical examination apparatus according to another exemplary embodiment of the present invention.

Bellows and the like can be used as a means for securing the medical examination apparatus according to the present invention inside the human body. That is, as shown in Figure 9, when the bellows 910 is mounted on the outside of the insertion portion and the pneumatic injection, the bellows rises out of the insertion portion as shown in the lower figure of Figure 9 to fix the health diagnostic apparatus inside the human body. In the case of using the bellows method, since the cross-sectional area of the bellows is small, the subject may feel pain when the stimulus is exerted to the human body. Thus, as shown in FIG. can do. The wing is made of soft material, and the area of contact with the human body is larger, which can minimize irritation.

On the other hand, when the outer fixing portion is a bellows method as shown in Figure 9 or 10, the oxygen saturation measuring unit or blood volume measuring unit may be included in the bellows. For example, in the case of the variable balloon type as shown in FIG. 5, an oxygen saturation measuring unit or a blood volume measuring unit including a light source 518, a light detector (not shown), a heater (not shown), and a temperature sensor 520 is separately present at the bottom of the insertion unit. do. However, in the bellows method of FIG. 9 or FIG. 10, the oxygen saturation measuring unit or the blood volume measuring unit may be included in the bellows to obtain more accurate measurement values.

In addition, when the bellows is used as shown in FIG. 9 or FIG. 10, the pressure sensor used in the variable balloon method may not be used.

11 is a view for explaining the operating principle of the laser Doppler interferometer used in one embodiment of the present invention.

As described above, a laser Doppler type interferometer (speedometer) may be used in the present invention. 11 briefly illustrates the principle of the laser Doppler method.

The laser light output from the laser light source 1102 is separated into the same light through the coupler 1104 and input to the circulator 1106 and the light measuring unit 1110, respectively. The laser light input to the circulator 1106 is irradiated to the blood flow through the variable focus lens 1108, and the laser light reflected from the blood flow is input to the circulator 1106 through the variable focus lens 1108.

The reflected light input to the circulator 1106 is processed by the light measuring unit 1110 using the laser light input through the coupler 1104 as a reference. The laser light processed by the optical measuring unit 1110 is separated into a sin signal and a cosine signal, and then synthesized into an arc tangent (arctan 1112). The synthesized signal is used to calculate the velocity of blood flow. Can be.

12 is a flow chart of a medical examination method according to an embodiment of the present invention.

Referring to FIG. 12, the laser light is first received (1202) and the focal length and the incident angle of the laser light are adjusted (1204). The laser light is then irradiated to the blood flowing at the measurement point (1206). At this time, the laser light reflected by the blood is detected (1208). The frequency change of the detected reflected laser light is then measured to determine the blood flow rate of the blood. Although not shown in FIG. 12, the method may further include determining at least one of oxygen saturation and blood volume of the blood by measuring the amount of light of the detected reflected laser light.

While the present invention has been described in connection with what is presently considered to be practical exemplary embodiments, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, But the present invention is not limited thereto.

Claims (12)

Insertion portion having a cylindrical shape;
Blood flow measuring unit for measuring the blood flow rate of the blood flowing to the measurement point; And
An outer fixing part for fixing the insertion part inside the human body,
The blood flow measuring unit
An optical connection line for receiving laser light from the outside; And
And a variable focus lens for adjusting an incident angle and a focal length of the laser light,
The blood flow measuring unit
Irradiating the laser light with the incident angle and the focal length controlled by the variable focus lens to the blood, and measuring the frequency change of the laser light reflected by the blood to determine the blood flow rate of the blood.
Medical diagnostic device for human body insertion.
The method of claim 1,
The insert
It includes a transparent window for allowing the laser light to be irradiated from the inside of the insertion portion to the outside
Medical diagnostic device for human body insertion.
The method of claim 1,
The blood flow measuring unit
Laser doppler interferometer
Medical diagnostic device for human body insertion.
The method of claim 1,
An oxygen saturation measuring unit for measuring oxygen saturation of the blood; And
Blood amount measuring unit for measuring the amount of blood
Medical diagnostic device for insertion of a human body further comprising.
5. The method of claim 4,
The oxygen saturation measuring unit or the blood volume measuring unit
A light source unit irradiating laser light to the blood;
A photodetector measuring an amount of laser light reflected from the blood;
A heat source unit for applying heat to the measurement point; And
It includes a temperature measuring unit for measuring the temperature of the measuring point,
Oxygen saturation or blood volume of the blood is determined using the light amount measured by the photodetector
Medical diagnostic device for human body insertion.
5. The method of claim 4,
The oxygen saturation measuring unit or the blood volume measuring unit
Two light source units for irradiating laser light having different wavelengths;
Two photodetectors for measuring the amount of laser light reflected from the blood; And
A heat source unit present at an intersection of diagonal lines connecting the two light source units and the two photodetectors,
The two photodetectors each measure an amount of laser light emitted from a light source unit positioned in a diagonal direction.
Medical diagnostic device for human body insertion.
The method of claim 1,
The outer fixing part
It is installed on the side of the insertion portion, and when the air is injected into the inner wall of the human body includes a variable balloon for fixing the insertion portion inside the human body,
The insert
An air hole for injecting air into the inflatable balloon; And
Including an air pressure measuring unit for measuring the air pressure inside the insertion portion
Medical diagnostic device for human body insertion.
5. The method of claim 4,
The outer fixing part
Including 2 or more bellows,
The oxygen saturation measuring unit or the blood volume measuring unit
Included in the outer fixing portion
Medical diagnostic device for human body insertion.
9. The method of claim 8,
The outer fixing part
And further comprising a vane for reducing the stimulus to said measuring point produced by said at least two bellows.
Medical diagnostic device for human body insertion.
The method of claim 1,
The insert
An inner fixing part for fixing at least one of the optical connection line, pneumatic connection line, electrical connection line included in the insertion portion
Medical diagnostic device for human body insertion.
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