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KR100492867B1 - Apparatus for Diagnosis of blood using PWM - Google Patents

Apparatus for Diagnosis of blood using PWM Download PDF

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KR100492867B1
KR100492867B1 KR10-2002-0072460A KR20020072460A KR100492867B1 KR 100492867 B1 KR100492867 B1 KR 100492867B1 KR 20020072460 A KR20020072460 A KR 20020072460A KR 100492867 B1 KR100492867 B1 KR 100492867B1
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pulse width
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width modulation
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KR20040043980A (en
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안재목
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생체계측신기술연구센터
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024Measuring pulse rate or heart rate
    • A61B5/02416Measuring pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analogue processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation

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  • Optics & Photonics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

본 발명은 PWM방식에 의한 혈중성분 진단장치에 관한 것으로, 그 목적은 모세혈관 속으로 입사시킨 특정 파장의 입사파에 대한 투과율은 혈관 체적변화율과 혈중 헤모글로빈의 농도에 따라 변하는데, 그에 따라 미세한 투과 및 반사신호를 1차 증폭하고, 1차 증폭된 신호를 PWM신호로 변환 하여 증폭하는 방식으로써, 증폭에 따른 노이즈를 제거할 뿐만 아니라 작은 입력신호로도 고안한 PWM증폭률에 의해 큰 출력신호를 제어가 가능하도록 하는데 있다.The present invention relates to an apparatus for diagnosing blood components by a PWM method, and its purpose is that the transmittance of incident waves of a specific wavelength incident into the capillaries varies depending on the rate of change of blood volume and the concentration of hemoglobin in the blood. And amplify the reflected signal first, and convert the first amplified signal into a PWM signal to amplify the signal.In addition to removing noise due to amplification, the large amplified signal is controlled by a PWM amplification ratio designed as a small input signal. Is to make it possible.

본 발명의 목적은 소정의 신체부위의 혈관에 광원을 조사하고, 조사된 광원이 혈관을 통과 또는 반사된 광신호를 입사하여 전기적신호로 변환하는 광센서, 광센서로부터 출력된 아날로그 검지신호를 아날로그/디지털변환부를 통해 디지털 검지신호로 변환하여 혈중성분의 농도 등을 진단하는 혈중성분 농도의 무혈측정장치에 있어서, 광센서로부터 변환 출력된 아날로그 검지신호를 소정레벨로 증폭하는 제 1 증폭기, 제 1 증폭기를 통해 증폭된 아날로그 검지신호를 펄스폭변조하여 출력하는 펄스폭변조발생부, 펄스폭변조발생부로부터 출력된 펄스폭변조신호를 저역 필터링하는 저역통과필터, 저역통과필터를 통해 출력된 신호를 2차 증폭하여 아날로그/디지털변환부로 입력시키는 제 2 증폭기, 아날로그/디지털변환부로부터 출력된 디지털 검지신호를 분석하여 혈관 및 혈중성분을 진단하는 마이크로프로세서를 포함하여 이루어짐을 특징으로 한다.An object of the present invention is to irradiate a light source to the blood vessels of a predetermined body part, and the light source is a light sensor for converting the light signal passed or reflected through the blood vessel and converted into an electrical signal, the analog detection signal output from the light sensor analog A blood pressure measurement device for converting a digital detection signal into a digital detection signal and diagnosing the concentration of blood components by using a digital conversion unit, comprising: a first amplifier and a first amplifier for amplifying an analog detection signal converted from an optical sensor to a predetermined level; A pulse width modulation generator for outputting the pulse width modulation signal amplified by the amplifier, and a low pass filter for low-pass filtering the pulse width modulation signal output from the pulse width modulation generator, and a signal output through the low pass filter. A second amplifier for second amplification and input to the analog / digital converter, digital detection signal output from the analog / digital converter The analysis will be characterized by a yirueojim including microprocessor to diagnose a blood vessel and the blood component.

Description

펄스폭변조 방식에 의한 혈중성분 진단장치 {Apparatus for Diagnosis of blood using PWM}Apparatus for Diagnosis of Blood Using PWM}

본 발명은 혈중성분의 무혈 진단시스템에 관한 것으로서, 보다 상세하게는 혈관 체적변화율과 혈중 헤모글로빈의 농도에 따라 모세혈관 속으로 입사시킨 특정 파장의 입사파에 대한 투과하여 반사된 미세한 반사신호를 펄스폭변조(Pulse Width Modulation : 이하 "PWM"이라 약칭함) 방식에 의하여 소정 레벨로 증폭하도록 하는 PWM방식에 의한 혈중성분 진단장치에 관한 것이다.The present invention relates to a blood-free diagnosis system of blood components, and more particularly, pulse width of a small reflection signal transmitted through and reflected on an incident wave of a specific wavelength incident into a capillary tube according to the rate of change of blood volume and the concentration of hemoglobin in the blood. The present invention relates to an apparatus for diagnosing blood components by a PWM method for amplifying to a predetermined level by a pulse width modulation (hereinafter, abbreviated as "PWM") method.

일반적으로 무혈진단시스템은 측정하고자 하는 신체 일부에 특정파장의 광을 조사하고, 광이 조사된 부위에서 반사 또는 투과된 광을 검출하여 헤모글로빈, 글루코스, 콜레스테롤, 알코올 및 빌리루빈 등, 혈중성분의 농도를 측정할수 있게 된다.In general, a blood-free diagnostic system irradiates a specific wavelength of light to a part of the body to be measured, and detects the light reflected or transmitted from the irradiated part to measure the concentration of blood components such as hemoglobin, glucose, cholesterol, alcohol and bilirubin. You can measure it.

종래 기술에 따른 무혈진단 시스템은 대한민국특허등록 "제 10-0165522 호"(혈중성분 무혈진단을 위한 최적지점 검색장치 및 이를 이용한 무혈진단기)에 개시되어 있다.The blood-free diagnostic system according to the prior art is disclosed in the Republic of Korea Patent Registration No. 10-0165522 (Optimum spot search apparatus and blood-free diagnostic device using the same) for blood component-free diagnosis.

도 1은 종래기술에 따른 혈중성분 무혈진단을 위한 최적지점 검색장치의 블록 구성도로서, 피검사자의 진단부위(10)에 소정 파장의 광신호를 조사하기 위한 광발생부(12)와, 조사된 광이 피검사자의 혈중성분에 반사 혹은 투과될 때의 광량을 검출하기 위한 광검출부(14)와, 광발생부(14)를 구동하기 위한 구동부(18)와, 광검출부(14)에서 출력된 검출신호를 증폭하기 위한 증폭기(13)와, 증폭기(13)의 출력신호를 필터링하기 위한 필터(15)와, 필터(15)에서 출력된 신호를 입력하여 디지털 데이터로 변환하기 위한 아날로그/디지털 변환부(16)와, 소정의 최적 진단지점 검색방법이 저장되어 있는 메모리(24)와, 사용자의 명령이 입력되는 키패드(17)와, 구동부(18)와 아날로그/디지털 변환부(16)와 키패드(17) 및 메모리(24)가 접속되며, 사용자가 입력한 명령에 따라 메모리(24)에 저장된 최적 진단지점 검색방법을 수행하는 마이크로프로세서(20) 및 마이크로프로세서(20)에 접속되며, 광검출부(14)에서 최대 검출신호가 검출될 때, 검출된 값과 상기 검출된 값이 최대 검출값이라는 것을 표시하기 위한 표시부(22)를 구비하고 있다. 1 is a block diagram of an optimal point search apparatus for blood component acuity diagnosis according to the prior art, the light generating unit 12 for irradiating an optical signal of a predetermined wavelength to the diagnosis site 10 of the examinee, The light output unit 14 for detecting the amount of light when the light is reflected or transmitted through the blood component of the test subject, the drive unit 18 for driving the light generation unit 14, and the detection output from the light detection unit 14 An amplifier 13 for amplifying the signal, a filter 15 for filtering the output signal of the amplifier 13, and an analog / digital converter for inputting the signal output from the filter 15 and converting the signal into digital data (16), a memory (24) storing a predetermined optimal diagnosis point search method, a keypad (17) into which a user's command is input, a driver (18), an analog / digital converter (16), and a keypad ( 17) and the memory 24 are connected, the memo according to the command input by the user It is connected to the microprocessor 20 and the microprocessor 20 which perform the optimal diagnostic point search method stored in 24, and when the maximum detection signal is detected by the photodetector 14, the detected value and the detected value The display part 22 for displaying that this is a maximum detection value is provided.

이와 같은 구비된 혈중성분 무혈진단을 위한 최적지점 검색장치는 사용자의 개시 명령이 키패드(17)로 입력되면, 마이크로프로세서(20)는 소정의 기준값을 설정하고, 구동부(18)에 소정신호를 인가하여 구동부(18)를 동작시킨다. 구동부(18)가 동작되면 광 발생부(12)에서는 소정의 광을 발생하여 진단부위(10)에 광을 조사하게 된다. 진단부위(10)에 조사된 광 중 반사된 광은 광검출부(14)에서 검출되고 증폭기(13)에서 증폭되며 필터(15)에 의해 필터링 되는데, 아날로그/디지털 변환부(16)를 사용하여 이 신호를 디지털 데이터로 변환한다. When the user's start command is inputted to the keypad 17, the microprocessor 20 sets a predetermined reference value and applies a predetermined signal to the driver 18. To operate the driving unit 18. When the driving unit 18 is operated, the light generating unit 12 generates predetermined light to irradiate light to the diagnosis unit 10. The reflected light among the light irradiated to the diagnostic portion 10 is detected by the photodetector 14, amplified by the amplifier 13, and filtered by the filter 15. Convert the signal to digital data.

마이크로프로세서(20)에서는 상기 변환된 디지털 데이터의 값, 즉 검출값과 설정된 기준값을 비교하여 검출값이 설정된 기준값보다 작은 경우, 검출값이 기준값 보다 크거나 같은 경우, 기준값을 검출값으로 치환한다. 표시부(22)에 검출값으로 치환된 기준값을 표시한다.The microprocessor 20 compares the value of the converted digital data, that is, the detected value and the set reference value, and replaces the reference value with the detected value when the detected value is greater than or equal to the reference value. The display unit 22 displays the reference value substituted with the detected value.

이와 같은 무혈진단방법은 다수의 광을 사용하고 잡음성분을 제거하여 잡음성분에 대한 영향을 최소화할 수 있으므로 혈액중의 농도가 매우 작은 성분도 정확하게 측정할 수 있는 잇점이 있다.Such a bloodless diagnosis method has the advantage that it is possible to accurately measure even a very small concentration in the blood because it can minimize the effect on the noise component by using a plurality of light and remove the noise component.

그러나, 이와 같은 종래기술에 따른 혈중성분 무혈진단을 위한 최적지점 검색장치는 실제로 입사파에 대한 투과 및 반사신호가 매우 작아서 증폭에 따른 노이즈가 발생하는 문제점이 있으며, 전치증폭기의 입력회로에서 최종 출력회로까지의 증폭률을 수 천배 이상 이득이 필요하게 되는 문제점이 있었다.However, such an optimal point search apparatus for blood component acuity diagnosis according to the related art has a problem in that noise due to amplification is generated because the transmission and reflection signals for incident waves are very small, and the final output from the input circuit of the preamplifier There was a problem that the gain of the amplification to the circuit is required to be several thousand times or more.

본 발명은 상기한 종래기술의 제반 문제점을 해결하기 위한 것으로, 그 목적은 모세혈관 속으로 입사시킨 특정 파장의 입사파에 대한 투과율은 혈관 체적변화율과 혈중 헤모글로빈의 농도에 따라 변하는데, 그에 따라 미세한 투과 및 반사신호를 1차 증폭하고, 1차 증폭된 신호를 PWM신호로 변환하여 증폭하는 방식으로써, 증폭에 따른 노이즈를 제거할 뿐만 아니라 작은 증폭률로도 출력신호를 제어가 가능하도록 하는 PWM방식에 의한 혈중성분 진단장치를 제공함에 있다. The present invention is to solve the above-mentioned problems of the prior art, the purpose is that the transmittance of the incident wave of a specific wavelength incident into the capillaries varies depending on the rate of blood vessel volume change and the concentration of hemoglobin in the blood, accordingly It is a method of amplifying transmission and reflection signals first, and converting the first amplified signal into PWM signal to amplify it. The present invention provides a diagnostic device for blood components.

본 발명의 목적을 달성하기 위한 PWM방식에 의한 혈중성분 진단장치는 소정의 신체부위의 혈관에 광원을 조사하고, 조사된 광원이 상기 혈관을 통과 또는 반사된 광신호를 입사하여 전기적신호로 변환하는 광센서와, 상기 광센서로부터 출력된 아날로그 검지신호를 아날로그/디지털변환부를 통해 디지털 검지신호로 변환하여 혈중성분의 농도 등을 진단하는 혈중성분 농도의 무혈측정장치에 있어서, 상기 광센서로부터 변환 출력된 아날로그 검지신호를 소정레벨로 증폭하는 제 1 증폭기와, 상기 제 1 증폭기를 통해 증폭된 아날로그 검지신호를 펄스폭변조하여 출력하는 펄스폭변조발생부와, 상기 펄스폭변조발생부로부터 출력된 펄스폭변조신호를 저역 필터링하는 저역통과필터와, 상기 저역통과필터를 통해 출력된 신호를 2차 증폭하여 상기 아날로그/디지털변환부로 입력시키는 제 2 증폭기와, 상기 아날로그/디지털변환부로부터 출력된 디지털 검지신호를 분석하여 혈관 및 혈중성분을 진단하는 마이크로프로세서를 포함하여 이루어짐을 특징으로 한다.In order to achieve the object of the present invention, an apparatus for diagnosing blood components using a PWM method irradiates a light source to blood vessels of a predetermined body part, and converts the light source into an electrical signal by irradiating the light signal passing or reflected through the blood vessel. An optical sensor and a blood component concentration measurement device for diagnosing the concentration of blood components by converting an analog detection signal output from the optical sensor into a digital detection signal through an analog / digital conversion unit, the output of the conversion from the optical sensor A first amplifier for amplifying the analog detection signal to a predetermined level, a pulse width modulation generator for pulse width modulating and outputting the analog detection signal amplified by the first amplifier, and a pulse output from the pulse width modulation generator A low pass filter for low pass filtering the width modulated signal, and a second amplification of the signal output through the low pass filter And a microprocessor for diagnosing blood vessels and blood components by analyzing a second amplifier inputted to the digital converter and a digital detection signal output from the analog / digital converter.

이와 같이 이루어진 본 발명을 첨부된 도면을 참조하여 상세히 설명하면 다음과 같다. The present invention made as described above will be described in detail with reference to the accompanying drawings.

도 2는 본 발명의 일 실시 예에 따른 PWM방식에 의한 혈중성분 진단장치는 소정의 신체부위의 혈관에 광원을 조사하고, 조사된 광원이 상기 혈관을 통과 또는 반사된 광신호를 입사하여 전기적신호로 변환하는 광센서(100)와, 상기 광센서(100)로부터 출력된 아날로그 검지신호를 소정레벨로 증폭하는 제 1 증폭기(102)와, 상기 제 1 증폭기(102)를 통해 증폭된 아날로그 검지신호를 PWM하여 출력하는 PWM발생부(110)와, 상기 PWM발생부(110)로부터 출력된 PWM신호를 저역 필터링하는 저역통과필터(LPF : Low Pass Filter)(112)와, 상기 LPF(112)를 통해 출력된 직류전압신호를 신호를 2차 증폭하는 제 2 증폭기(104)와, 제 2 증폭기(104)를 통해 출력된 아날로그신호를 디지털신호로 변환하는 아날로그/디지털(A/D)변환부(106)와, 상기 A/D변환부(106)로부터 출력된 디지털신호를 분석하여 혈관의 체적변화율 및 혈중성분의 농도를 진단하는 마이크로프로세서(108)로 구성된다.2 is a device for diagnosing blood components by a PWM method according to an embodiment of the present invention, irradiating a light source to blood vessels of a predetermined body part, and irradiating a light signal passing or reflected through the blood vessel to an electric signal. The optical sensor 100 for converting the signal to the first, the first amplifier 102 for amplifying the analog detection signal output from the optical sensor 100 to a predetermined level, and the analog detection signal amplified by the first amplifier 102 PWM generator 110 for outputting the PWM, a low pass filter (LPF: Low Pass Filter) (112) for low-pass filtering the PWM signal output from the PWM generator 110, and the LPF (112) A second amplifier 104 which amplifies the DC voltage signal output through the second signal, and an analog / digital (A / D) converter for converting the analog signal output through the second amplifier 104 into a digital signal ( 106 and the digital signal outputted from the A / D converter 106 And a microprocessor 108 for diagnosing the volume change rate of blood vessels and the concentration of blood components.

이와 같이 구성된 본 발명 실시예에 따른 작용을 첨부된 도 2를 참조하여 보다 상세히 설명하면 다음과 같다.When described in more detail with reference to Figure 2 attached to the operation according to the embodiment of the present invention configured as follows.

먼저, 본 발명은 혈관의 체적변화율과 혈중 헤모글로빈의 농도에 따라 변하는 모세혈관 속으로 입사시킨 특정파장의 입사파에 대한 투과 또는 반사광을 입사하여 검지된 미세신호를 증폭할 때 PWM 방식으로 전치증폭하도록 하므로서, 증폭효율을 높이도록 하는 것이다.First, the present invention is to pre-amplify by a PWM method when amplifying the detected micro-signal by incidence of the transmitted or reflected light to the incident wave of a specific wavelength incident into the capillary tube varying according to the volume change rate of blood vessels and the concentration of hemoglobin in the blood By doing so, the amplification efficiency is to be increased.

도 2는 본 발명의 실시예에 따른 PWM방식에 의한 혈중성분 진단장치의 블록 구성도로서, 광센서(100)를 통해 입사된 광신호는 제 1 증폭기(102)를 통해 피크신호를 소정 레벨로 증폭한다.2 is a block diagram of a blood component diagnosis apparatus using a PWM method according to an exemplary embodiment of the present invention, in which an optical signal incident through the optical sensor 100 sets a peak signal through a first amplifier 102 to a predetermined level. Amplify.

제 1 증폭기(102)를 통해 증폭된 검지신호는 필터링하지 않고, PWM발생부(110)를 통하여 검지신호를 펄스폭 변조를 한 후 PWM 신호로 출력한다. PWM신호로 변환하기 위해서 수동소자로 구현한 삼각파를 발생시켜 비교기(도면에 미도시)를 거쳐 PWM 신호를 발생시키게 된다.The detection signal amplified by the first amplifier 102 is not filtered, and the pulse width modulation of the detection signal is output through the PWM generator 110 and then output as a PWM signal. To convert into a PWM signal, a triangular wave implemented with a passive element is generated to generate a PWM signal through a comparator (not shown).

상기 PWM발생부(110)를 통해 발생된 PWM신호는 저역통과필터(112)를 통하여 직류전압으로 변환하여 제 2 증폭기(104)로 출력한다.The PWM signal generated through the PWM generator 110 is converted into a DC voltage through the low pass filter 112 and output to the second amplifier 104.

제 2 증폭기(104)에서는 상기 저역통과필터(112)에서 출력된 신호를 2차 증폭하게 되는데, 이때, 제 2 증폭기(104)에서는 입사광의 최대 첨두치의 변화율을 PWM신호의 변화율로 변경하여 2차 증폭하는 것이므로, 증폭률을 기존의 증폭률 보다 5배 이상 줄이더라도 검출할 수 있는 충분히 큰 신호를 발생할 수 있게 된다. In the second amplifier 104, the signal output from the low pass filter 112 is second amplified. In this case, in the second amplifier 104, the rate of change of the maximum peak value of incident light is changed to the rate of change of the PWM signal. Since it is amplified, even if the amplification rate is reduced by five times or more than the existing amplification rate, it is possible to generate a sufficiently large signal that can be detected.

상기 제 2 증폭기(104)를 통해 증폭된 아날로그 PWM신호는 A/D변환부(106)를 통해 디지털 PWM신호로 변환되어 마이크로프로세서(108)로 출력하게 된다.The analog PWM signal amplified by the second amplifier 104 is converted into a digital PWM signal through the A / D converter 106 and output to the microprocessor 108.

여기서, 입력된 아날로그 입력신호가 대단히 미약하여 한번의 PWM방식으로 원하는 증폭률을 만들 수 없을 경우, 다음 단에서 PWM방식에 의한 PWM 증폭을 수행하는 PWM증폭부(도면에 미도시)를 추가할 수 있도록 한다.Here, if the input analog input signal is so weak that the desired amplification factor cannot be achieved with a single PWM method, a PWM amplifier (not shown in the drawing) that performs PWM amplification by the PWM method can be added in the next step. do.

마이크로프로세서(108)에서는 입력된 PWM신호의 변화폭으로 심박수를 연산함과 아울러 심장박동 신호인 맥박을 분석하게 된다. The microprocessor 108 calculates the heart rate based on the change width of the input PWM signal and analyzes the heartbeat signal pulse.

뿐만 아니라, 마이크로프로세서에서 A/D변환부를 활용하지 않고 PWM신호의 변화폭으로 두 파장의 흡수도를 예측할 수 있다. PWM의 펄스 폭(DUTY%)이 실시간으로 변하게 되고 현재의 'DUTY%'와 다음신호의 최대 'DUTY%' 사이의 간격 시간을 측정하여 연산하면 심박수를 얻을 수 있고 듀티의 최소 최대값을 이용해서 혈중 산소농도를 연산하게 된다.In addition, the absorbance of two wavelengths can be predicted by the change width of the PWM signal without using the A / D converter in the microprocessor. The pulse width (DUTY%) of the PWM is changed in real time, and the measurement is performed by measuring the interval time between the current 'DUTY%' and the maximum 'DUTY%' of the next signal to obtain the heart rate and using the minimum maximum value of the duty. Oxygen levels in the blood are calculated.

이상에서 본 발명에 따른 바람직한 실시예에 대해 설명하였으나, 전치증폭을 위해 PWM신호를 발생 및 증폭하는 증폭기는 2차 PWM증폭하는 등 다양하게 변형이 가능하며, 본 기술분야에서 통상의 지식을 가진자라면 본 발명의 특허청구범위를 벗어남이 없이 다양한 변형예 및 수정예를 실시할 수 있을 것으로 이해된다. Although a preferred embodiment according to the present invention has been described above, an amplifier for generating and amplifying a PWM signal for preamplification may be variously modified, such as a second PWM amplification, and has a general knowledge in the art. It will be understood that various modifications and variations may be made without departing from the scope of the claims of the present invention.

이상에서 설명한 바와 같이, 본 발명에 따른 PWM방식에 의한 혈중성분 진단장치는 PWM방식의 전치증폭기로 광센서에서 출력된 미세한 검지신호를 증폭하므로, 주변의 노이즈의 영향을 최소화하여 검지신호를 증폭할 수 있으며, 그에 따라 심박수 측정, 맥박측정 및 혈중 농도 등의 원하는 진단을 보다 정확히 산출할 수 있는 효과가 있다. As described above, the PWM component blood system diagnostic apparatus according to the present invention amplifies the minute detection signal output from the optical sensor with a PWM pre-amplifier, thereby minimizing the influence of ambient noise to amplify the detection signal. Therefore, there is an effect that can more accurately calculate the desired diagnosis, such as heart rate measurement, pulse measurement and blood concentration.

도 1은 종래기술에 따른 혈중성분 무혈진단을 위한 최적지점 검색장치 및 이를 이용한 무혈진단기의 블록 구성도이고,1 is a block diagram of an optimal point search apparatus for blood component diagnosis and bloodless diagnostic apparatus using the same according to the prior art,

도 2는 본 발명의 실시예에 따른 펄스폭변조 방식에 의한 혈중성분 진단장치의 블록 구성도이다.2 is a block diagram of an apparatus for diagnosing blood components by a pulse width modulation method according to an exemplary embodiment of the present invention.

< 도면의 주요부분에 대한 부호의 설명 ><Description of Symbols for Major Parts of Drawings>

100 : 광세선 102, 104 : 제 1, 제 2 증폭기100: optical thin line 102, 104: first and second amplifiers

106 : A/D변환부 108 : 마이크로프로세서106: A / D conversion unit 108: microprocessor

110 : 펄스폭변조발생부 112 : 저역통과필터110: pulse width modulation generator 112: low pass filter

Claims (6)

소정의 신체부위의 혈관에 광원을 조사하고, 조사된 광원이 상기 혈관을 통과 또는 반사된 광신호를 입사하여 전기적신호로 변환하는 광센서와, 상기 광센서로부터 출력된 아날로그 검지신호를 아날로그/디지털변환부를 통해 디지털 검지신호로 변환하여 혈중성분의 농도 등을 진단하는 혈중성분 농도의 무혈측정장치에 있어서,An optical sensor irradiates a light source to blood vessels of a predetermined body part, and converts an optical signal through which the irradiated light source passes or reflects the blood vessel into an electrical signal, and converts an analog detection signal output from the optical sensor into analog / digital signals. In the blood-free measurement device of the blood component concentration to convert the digital detection signal through the converter for diagnosing the concentration of blood components, etc., 상기 광센서로부터 변환 출력된 아날로그 검지신호를 소정레벨로 증폭하는 제 1 증폭기;A first amplifier for amplifying the analog detection signal converted and output from the optical sensor to a predetermined level; 상기 제 1 증폭기를 통해 증폭된 아날로그 검지신호를 펄스폭변조하여 출력하는 펄스폭변조발생부;A pulse width modulation generator for outputting the pulse width modulation by outputting the analog detection signal amplified by the first amplifier; 상기 펄스폭변조발생부로부터 출력된 펄스폭변조신호를 저역 필터링하는 저역통과필터;A low pass filter for low-pass filtering the pulse width modulation signal output from the pulse width modulation generator; 상기 저역통과필터를 통해 출력된 신호를 2차 증폭하여 상기 아날로그/디지털변환부로 입력시키는 제 2 증폭기; 및A second amplifier for secondly amplifying the signal output through the low pass filter and inputting the analog / digital converter; And 상기 아날로그/디지털변환부로부터 출력된 디지털 검지신호를 분석하여 혈관의 체적변화율 및 혈중성분의 농도를 산출하여 혈관 및 혈중성분을 진단함과 아울러 상기 펄스폭변조신호의 변화폭으로부터 심박수를 산출함과 아울러 맥박을 진단하는 마이크로프로세서를 포함하여 이루어짐을 특징으로 하는 펄스폭변조 방식에 의한 혈중성분 진단장치.By analyzing the digital detection signal output from the analog / digital converter, the volume change rate of blood vessels and the concentration of blood components are calculated to diagnose blood vessels and blood components, and the heart rate is calculated from the change width of the pulse width modulation signal. Device for diagnosing blood components by pulse width modulation method comprising a microprocessor for diagnosing pulse. 제 1 항에 있어서, The method of claim 1, 상기 광센서에서 출력된 아날로그 검지신호는 소정의 신체일부의 모세혈관을 투과한 광입자의 량을 검출하여 그 광량을 전기적인 아날로그신호로 변환된 것임을 특징으로 하는 펄스폭변조 방식에 의한 혈중성분 진단장치.The analog detection signal output from the optical sensor detects the amount of light particles passing through a capillary blood vessel of a predetermined body and converts the light amount into an electrical analog signal. . 제 1 항에 있어서,The method of claim 1, 상기 펄스폭변조발생부는 상기 제 1 증폭기를 통해 출력된 아날로그검지신호의 최대첨두치의 변화율을 펄스폭변조신호의 변화율로 변환하는 것을 특징으로 하는 펄스폭변조 방식에 의한 혈중성분 진단장치.And the pulse width modulation generator is configured to convert the rate of change of the maximum peak value of the analog detection signal output through the first amplifier into the rate of change of the pulse width modulation signal. 삭제delete 삭제delete 제 1 항에 있어서,The method of claim 1, 상기 펄스폭변조발생부에 부가하여 상기 아날로그 입력신호가 대단히 미약하여 한번의 펄스폭방식으로 원하는 증폭률을 만들 수 없을 경우, 다음 단에서 펄스폭변조방식으로 펄스폭변조 증폭을 수행하는 펄스폭변조증폭부를 더 포함하여 구성된 것을 특징으로 하는 펄스폭변조방식에 의한 혈중성분 진단장치.In addition to the pulse width modulation generator, if the analog input signal is so weak that the desired amplification rate cannot be made with a single pulse width method, a pulse width modulation amplification is performed in the next stage to perform pulse width modulation amplification with a pulse width modulation method. Blood component diagnosis device by the pulse width modulation method characterized in that it further comprises a unit.
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Publication number Priority date Publication date Assignee Title
WO1991000022A1 (en) * 1989-06-23 1991-01-10 Genencor International, Inc. Enzyme assisted degradation of surface membranes of harvested fruits and vegetables
JPH06121778A (en) * 1992-10-08 1994-05-06 Toshiba Corp Witching frequency generator
KR940013459A (en) * 1992-12-29 1994-07-15 최태영 Automatic blood sugar measuring device and measuring method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991000022A1 (en) * 1989-06-23 1991-01-10 Genencor International, Inc. Enzyme assisted degradation of surface membranes of harvested fruits and vegetables
JPH06121778A (en) * 1992-10-08 1994-05-06 Toshiba Corp Witching frequency generator
KR940013459A (en) * 1992-12-29 1994-07-15 최태영 Automatic blood sugar measuring device and measuring method

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