JPH03204803A - Adsorbent for peroxylipid - Google Patents

Abstract

PURPOSE:To obtain an adsorbent for peroxylipids, containing magnesium (meta) silicate aluminate as an active ingredient and capable of preventing or suppressing skin roughening, inflammations, pruritus, prickly heat, common acne, etc., of the skin. CONSTITUTION:An adsorbent for peroxylipids containing magnesium silicate aluminate and/or magnesium metasilicate aluminate in an amount of at least 0.1wt.% as an active ingredient. The aforementioned compound used has 0.001-500mum particle diameter and a granular, spherical or platy form is preferred in using for the skin. The above-mentioned compound is used as an active ingredient of a skin drug for external use, toilet water, beautifying solution, milky lotion or deodorant.

Description

Detailed Description of the Invention [Industrial Field of Application] The present invention is directed to lipid peroxide adsorbents, external skin preparations, lotions, and cosmetic products containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as active ingredients. Concerning liquids, emulsions, and deodorants.

[Conventional technology] Sebum is constantly secreted from the skin along with sweat, and many of the oils contained in these oils are converted into lipid peroxides through automatic air oxidation, photooxidation, etc., and are also used in cosmetics. Some oils easily convert into lipid peroxides, and these can have negative effects on the skin (rough skin, inflammation, itching, heat rash, etc.)
There is a risk of causing acne (acne). Therefore, in cosmetics, agents such as antioxidants, active oxygen scavengers, and ultraviolet absorbers are currently added to suppress the oxidative deterioration of the oils in sebum and the oils in cosmetic formulations.

[Problem to be solved by the invention 1 However, sebum is constantly secreted, and even if drugs such as antioxidants, active oxygen scavengers, and ultraviolet absorbers are added, the effects often do not last. In addition, it is not preferable from the viewpoint of safety to incorporate a sufficient amount in terms of effectiveness.

The present invention has been made in view of the above-mentioned problems of the prior art, and its object is to provide a skin external use characterized by using a powder having a lipid peroxide adsorption effect as a lipid peroxide adsorbent, and containing the same in the powder. The purpose is to obtain agents, lotions, serums, milky lotions, and deodorants.

As a result of intensive research in order to achieve the above object, the present inventors have revealed that magnesium aluminate silicate or magnesium aluminate metasilicate has lipid peroxide adsorption ability, and have found that magnesium aluminate silicate or magnesium aluminate metasilicate has lipid peroxide adsorption ability. The present inventors have discovered that they can obtain agents, external skin preparations, lotions, serums, emulsions, and deodorants, and have completed the present invention.

[Means for Solving the Problems] That is, the invention according to claim 1 is a lipid peroxide adsorbent containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient.

The invention according to claim 2 is an external preparation for skin containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient.

The invention according to claim 3 is a lotion containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient.

The invention according to claim 4 is a beauty serum containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient.

The invention according to claim 5 is a milky lotion containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient.

The invention according to claim 6 is a deodorant containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient.

The configuration of the present invention will be explained in detail below.

The present invention, which contains magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient, is a lipid peroxide adsorbent whose active ingredient is a powder capable of adsorbing lipid peroxide.

Lipid peroxide adsorbents mentioned here include, for example, lotions, creams, emulsions, makeup bases, basic cosmetics such as packs, facial creams, cleansing creams, cleaning materials such as soaps, foundations, white powders, lipsticks, rouges, etc. eyeliner,
Makeup cosmetics such as mascara, eye shadow, eyebrow makeup, and nail polish; topical deodorants such as deodorants and antiperspirants (aerosols, roll-ons, powders, pressed powders, creams, and sticks); shoe pads, disposable diapers, It refers to deodorants such as sanitary products, and its uses include cosmetics, quasi-drugs, pharmaceuticals, and sanitary products.

The particle size of the magnesium aluminate silicate and/or magnesium aluminate metasilicate used in the present invention is 0.001 to 500 μm.

Although any shape may be used, granular, spherical, and plate-like shapes are preferable when used on the skin or hair.

The amount of the magnesium aluminate silicate and/or magnesium aluminate metasilicate added to the lipid peroxide adsorbent is 0.1 to 100% by weight.

If it is less than 0.1%, the lipid peroxide adsorption effect is difficult to exhibit.

The present invention is an external skin preparation containing powder that has the ability to adsorb lipid peroxide.

The external skin preparations mentioned here include lotions, creams,
Basic cosmetics such as emulsions, makeup bases, packs, face wash creams, cleansing creams, cleaning materials such as soaps, makeup cosmetics such as foundation, white powder, lipstick, blusher, eyeliner, mascara, eyeshadow, eyebrows, nail polish, etc. It refers to external deodorants, such as deodorants and antiperspirants (aerosols, roll-ons, powders, pressed powder creams, and stickers), and its uses include cosmetics, quasi-drugs, and pharmaceuticals.

The particle size of the magnesium aluminate silicate and/or magnesium aluminate metasilicate used in the present invention is 0.001 to 500 um.

It may have any shape, but when used on the skin, granular, spherical, and plate-like shapes are preferred.

The amount of the above-mentioned magnesium aluminate silicate and/or magnesium aluminate metasilicate added to the skin external preparation is 0.1 to 100% by weight. If it is less than 0.1%, the lipid peroxide adsorption effect is difficult to exhibit.

Although it stagnates, the powder can be dispersed in the container by shaking the container, and its uses include cosmetics, quasi-drugs, and pharmaceuticals.

The particle size of the magnesium aluminate silicate and/or magnesium aluminate metasilicate used in the present invention is 0.001 to 500 μm.

Although any shape may be used, granular, spherical, and plate-like shapes are preferable in consideration of the feel on the skin.

The amount of magnesium aluminate silicate and/or magnesium aluminate metasilicate added to the lotion is 0.
．． It is 1 to 100% by weight. If it is less than 0.1%, the lipid peroxide adsorption effect is difficult to exhibit.

The present invention is a lotion containing powder that has the ability to adsorb lipid peroxide.

The lotion referred to here is generally called a powdered lotion, and when left standing, the powder sinks to the bottom layer of the container.The present invention is a beauty lotion containing powder that has the ability to adsorb lipid peroxide. .

The term beauty serum as used herein refers to a lotion with a product viscosity of 100 cpS or more and a milky lotion with an oil content of 10% or less, and its uses include cosmetics, quasi-drugs, and pharmaceuticals.

The particle size of the magnesium aluminate silicate and/or magnesium aluminate metasilicate used in the present invention is 0.001 to 500 μm.

Although any shape may be used, granular, spherical, and plate-like shapes are preferable in consideration of the feel on the skin.

The amount of magnesium aluminate silicate and/or magnesium aluminate metasilicate added to the serum is 0.
．． It is 1 to 100% by weight. If it is less than 0.1%, the lipid peroxide adsorption effect is difficult to exhibit.

The present invention is an emulsion containing a powder having an ability to adsorb lipid peroxide. .

The particle size of the magnesium aluminate silicate and/or magnesium aluminate metasilicate used in the present invention is 0.001 to 500 μm.

Although any shape may be used, granular, spherical, and plate-like shapes are preferable in consideration of the feel on the skin.

The amount of magnesium aluminate silicate and/or magnesium aluminate metasilicate added to the emulsion is 0.
It is 1 to 100% by weight. If it is less than 0.1%, it is difficult to achieve the adsorption effect of lipid peroxide.

The present invention is a deodorant containing powder that has the ability to adsorb lipid peroxide. .

The term deodorant here refers to deodorants and antiperspirants (aerosols,
Roll-on, powder pressed powder cream,
It refers to external deodorants such as sticks, shoe pads, disposable diapers, sanitary products, etc., and its uses include cosmetics, quasi-drugs, pharmaceuticals, and sanitary products.

The particle size of the magnesium aluminate silicate and/or magnesium aluminate metasilicate used in the present invention is 0.001 to 500 μm.

Although any shape may be used, granular, spherical, and plate-like shapes are preferable in consideration of the feel on the skin.

The amount of magnesium aluminate silicate and/or magnesium aluminate metasilicate added to the deodorant is 0.
．． It is 1 to 100% by weight. If it is less than 0.1%, the lipid peroxide adsorption effect is difficult to exhibit.

In addition to magnesium aluminate silicate and/or magnesium aluminate metasilicate, the lipid peroxide adsorbent, external skin preparation, lotion, beauty serum, emulsion, and deodorant of the present invention include cosmetics, quasi-drugs, etc. Any ingredient commonly used in pharmaceuticals, sanitary products, etc. can be incorporated within the range that does not impair the effect.

Such ingredients include, for example, water; avocado oil, almond oil, olive oil, crepe seed oil, sesame oil, sasanqua oil, safflower oil, soybean oil, Tuba oil, corn oil, rapeseed oil, persic oil, and castor oil. Fats and oils such as oil, sunflower oil, cottonseed oil, peanut oil, cacao oil, palm oil, coconut oil, beef oil, non-fat, hydrogenated oil, turd oil, pork oil, mink oil, egg yolk oil; spermaceti, shellac, beeswax ,
Waxes such as lanolin, liquid lanolin, carnauba wax, and candelilla wax; Hydrocarbons such as liquid paraffin, liquid polyisobutylene, squalane, pristane, petrolatum, paraffin, and ceresin; Dimethylpolysiloxane, methylphenylpolysiloxane, and methylhydrodiene polysiloxane , octamethylcyclotetrasiloxane,
Silicone oil such as decamethylcyclopentasiloxane;
Fatty acids such as succinic acid, tartaric acid, citric acid, undecylenic acid, lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, oleic acid, linoleic acid, ricinoleic acid, behenic acid; ethanol, isopropanol, lauryl alcohol, Alcohols such as cetanol, 2-hexyldecanol, stearyl alcohol, isostearyl alcohol, oleyl alcohol, lanolin alcohol; ethylene glycol, diethylene glycol monoethyl ether, triethylene glycol, polyethylene glycol, propylene glycol, 1.3
- Polyhydric alcohols such as butylene glycol, glycerin, and batyl alcohol; Saccharides such as glucose, sucrose, lactose, xylitol, sorbitol, mannitol, and maltitol; diisopropyl adipate, hexyldecyl isostearate, cetyl isooctanoate, oleyl oleate, Esters such as decyl oleate, lanolin acetate, butyl stearate, isopropyl myristate, diethyl phthalate, hexyl laurate; aluminum stearate, calcium stearate, magnesium stearate, zinc stearate, aluminum myristate, calcium myristate, myristic magnesium acid, zinc myristate, aluminum palmitate,
Calcium palmitate, magnesium palmitate,
Metallic soaps such as zinc palmitate, zinc laurate, zinc undecylenate, calcium acetate; natural water-soluble substances such as gum arabic, atrium alginate, casein, carrageenan, gum karaya, agar, quince seed, gelatin, dextrin, starch, tragacanth, pectin, etc. High molecular compounds; natural pigments such as chlorophyll and β-carotene;
Sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, sorbitan trioleate, diglycerol pent-2-ethylhexylate, sorbitan, tetra-2-ethylhexyl Sorbitan fatty acid esters such as acid diglycerol sorbitan, monocottonseed oil fatty acid glycerin, monoerucic acid glycerin, sesquioleic acid glycerin, monostearic acid glycerin, α, α′-
Glycerol polyglycerol fatty acids such as glyceryl oleate, glyceryl monostearate and malic acid, propylene glycol fatty acid esters such as propylene glycol monostearate, lipophilic nonionic surfactants such as hydrogenated castor oil derivatives, and glycerin alkyl ethers. Agent; POE sorbitan fatty acid esters such as POE-sorbitan monooleate, POE-sorbitan monostearate, POE-sorbitan monooleate, POE-sorbitan tetraoleate, POE sorbitan monolaurate, POE sorbitan monooleate, POE sorbitol POE-sorbit fatty acid esters such as pentaoleate, POE sorbitol monostearate, POE glycerin monostearate, PO
POE-glycerin fatty acid esters such as E-glycerin monoisostearate and POE-glycerin triisostearate, POE-fatty acid esters such as POE-monooleate, POE-distearate, POE-monooleate, and ethylene glycol distearate, POE lauryl ether , POE oleyl ether, POE stearyl ether, POE behenyl ether, POE2-
POE alkyl ethers such as octyl dodecyl ether, POE cholestanol ether, POE-octyl phenyl ether, POE nonylphenyl ether, POE
POE-alkyl phenyl ethers such as OE dinonylphenyl ether, Pluronic type surfactants such as Pluronic, POE-POP cetyl ether, POE-
POE2-decyltetradecyl ether, POE-PO
P Monobutyl Ether, POE-POP Hydrogenated Lanoun P
POE-POP alkyl ethers such as OE-POP glycerin ether, tetra-POE/tetra-POP ethylenediamine condensates such as Tetronic, POE castor oil, POE hydrogenated castor oil, POE hardened castor monoisostearate OE hydrogenated castor oil towa POE castor oil hardened castor oil derivatives such as isostearate, POE-hydrogenated castor oil monopyroglutamic acid monoisostearic acid diester, POE hydrogenated castor oil maleic acid, OE beeswax lanolin derivatives such as OE sorbit beeswax,
Alkanolamides such as coconut oil fatty acid jetanolamide, lauric acid monoethanolamide, fatty acid isopropanolamide, POE propylene glycol fatty acid ester, POE alkylamine, POE-fatty acid amide, sucrose fatty acid ester, POE-nonylphenyl formaldehyde condensate , alkyl ethoxydimethylamine oxide, trioleyl phosphoric acid, etc.; soap base, fatty acid soaps such as sodium laurate, sodium palmitate, higher alkyl sulfate esters such as sodium lauryl sulfate, lauryl sulfate, etc. salt, POE lauryl sulfate triethanolamine, P
Alkyl ether sulfate ester salts such as OE sodium lauryl sulfate, H- such as sodium lauroyl sarcosine, etc.
Higher fatty acid amide sulfonates such as acyl sarcosinate, sodium tomilistoyl methyl taurate, sodium coconut oil fatty acid methyl tauride, sodium lauryl methyl tauride, phosphoric acids such as POE sodium oleyl ether phosphate, POE stearyl ether phosphate, etc. Ester salts, sulfosuccinates such as sodium di-2-ethylhexyl sulfosuccinate, monolauroyl monoethanolamide polyoxyethylene sodium sulfosuccinate, sodium lauryl polypropylene glycol sulfosuccinate, sodium linear dodecylbenzene sulfonate, trilinear dodecylbenzene sulfonate Ethanolamine, alkylbenzene sulfonates such as linear dodecylbenzenesulfonic acid, N-acyl glutamates such as monosodium trauroylglutamate, disodium N-stearoylglutamate, monosodium N-myristoyl-L-glutamate, hydrogenated coconut oil fatty acid glycerin Higher fatty acid ester sulfate salts such as sodium sulfate, sulfated oils such as funnel oil, POE-
Alkyl ether carboxylic acid, POE-alkyl allyl ether carboxylate, α-olefin sulfonate,
Anionic surfactants such as higher fatty acid ester sulfonate, secondary alcohol sulfate, higher fatty acid alkylolamide sulfate, sodium lauroyl monoethanolamide succinate, topalmitoyl aspartate ditriethanolamine, sodium caseinate;
Polyether modified silicone, amino modified silicone,
Alkyl-modified silicone, alcohol-modified silicone,
Silicone surfactants such as carboxylic acid-modified silicones; perfluoroalkyl carboxylates, perfluoroalkyl phosphates, perfluoroalkyltrimethylammonium salts, perfluoroalkyl betaines, perfluoroalkylamine oxides, perfluoroalkyl EO adducts Fluorinated surfactants such as butyl paraoxybenzoate, propyl paraoxybenzoate, ethyl paraoxybenzoate, methyl paraoxybenzoate, etc.; Vitamins such as vitamin A1 vitamin D1 vitamin E1 vitamins; estradiol, ethinylestradiol, Hormones such as cortisone; antiperspirants such as aluminum hydroxychloride, aluminum chloride, aluminum sulfate, basic aluminum bromide, aluminum phenolsulfonic acid, tannic acid, aluminum naphthalene sulfonic acid, basic aluminum iodide; urocanic acid, cinoxate, etc. UV absorbers; anti-inflammatory agents such as allantoin, aloe powder, and guaidulene? 3,4.4
- Trichlorocarbanilide (T, C, C), triethyl citrate (T, E, C), benzalkonium chloride, pensitonium chloride, alkyltrimethylammonium chloride, resorcinol, phenol, sorbic acid, salicylic acid, hexachlorophene, etc. Fungicides; other powders;
Lavender, which is a natural plant fragrance; Essential oils such as lemon, lime, jasmine, mint, peppermint, rose, and camphor; Animal fragrances such as musk, civet, and castorium; and other synthetic fragrances; Freon 11, Freon 12, Freon 114, and propane. Propellants such as isobutane, n-butane and mixtures thereof, liquefied petroleum gas (LPG), n-pentane, isopentane, n-hexane, dimethyl ether, chlorinated hydrocarbons; carbon dioxide gas,
Examples include compressed gases such as nitrogen gas and laughing gas.

The magnesium aluminate silicate and magnesium aluminate metasilicate used in the present invention may be powders that have been surface-modified in advance, as long as the adsorption of lipid peroxide is not lost.

Examples of surface modifiers include ester oils, hydrocarbon oils, fatty acids, silicone oils (for example, methylhydrodiene polysiloxane, 1.3.5.7-titramethylcyclotetrasiloxane, dimethylpolysiloxane, methylphenylpolysiloxane, etc.). ), waxes such as spermaceti wax, wood wax, shellac, beeswax, lanolin, carnauba wax, and candelilla wax, and silane coupling agents (e.g., vinyltrichlorosilane, triethoxyvinylsilane, 3-chloropropyltrimethoxysilane) etc.) silylating agents (e.g., trimethylchlorosilane, hexamethyldisilazane, diethylaminotrimethylsilane, etc.), titanate coupling agents (e.g., methyltrichlorotitanium, isopropyltriisostearoyl titanate, tetraoctyl bis(ditridecylphosphate) titanate, bis (dioctyl pyrophosphate) ethylene titanate, etc.), monomers forming synthetic polymers (e.g. monomers for polyamides such as caprolactam, monomers for polyolefins such as ethylene and propylene, styrene monomers, divalent aromatic phenols, Monomers for polyesters such as bisphenol A, monomers for acrylic resins such as methyl methacrylate, methacrylic acid, butyl acrylate, monomers for epoxy resins such as bisphenol A and epichlorohydrin, monomers for fluororesins, monomers for silicone resins, etc.), Surfactants such as alkylaryl sulfonates, higher alcohol sulfates, higher alcohol phosphates, etc., silicone interfaces such as polyether-modified silicones, amino-modified silicones, alkyl-modified silicones, alcohol-modified silicones, carboxylic acid-modified silicones, etc. Active agents, perfluoroalkyl carboxylates, perfluoroalkyl phosphate esters, perfluoroalkyl trimethyl ammonium salts, perfluoroalkyl betaines, perfluoroalkyl amine oxides, perfluoroalkyl EO adducts and other fluorinated surfactants, stearin Aluminum acid, calcium stearate, magnesium stearate, zinc stearate, aluminum myristate, calcium myristate, magnesium myristate, zinc myristate, aluminum palmitate, calcium palmitate, magnesium palmitate, zinc palmitate, zinc laurate, Examples include metal soaps such as zinc undecylenate and calcium acetate, silicone resins, silicone rubbers, gelatin, collagen, keratin, fibroin, dextrin, and cyclodextrin. As a modification method, any conventional method may be used, such as modification by coating, topochemical modification, mechanochemical modification, modification by encapsulation, and modification by radiation irradiation. Examples include modification methods such as modification by plasma irradiation, and treatment is carried out under conditions such as in a gas phase, in a liquid phase, or under vacuum.

Alternatively, the surface may be modified by plasma irradiation or the like without using a modifier.

[Examples] Next, examples of each section will be described. The present invention is not limited to these. The blending amount is in weight%.

Example 1 Powder foundation (1) Sericite 47.2
8(2) Talc 15
．． 0(3) Magnesium aluminate silicate 15.
0(4) Titanium dioxide 6.5
(5) Iron oxide 3.5 (
6) Trimethylolpropane triisostearate 5.0 (7) Squalane 6.0 (
8) Sorbitan sesquiolate 1.0 (9
) Preservative 0.5 (10
) Oxidizing preservative 0.02 (1
1) Fragrance 0.2 (Manufacturing method) The above (1) to (5) are mixed in a Henschel mixer, a heated and dissolved solution of (6) to (11) is added thereto, and the mixture is mixed and pulverized. This was molded into a medium plate to obtain a powder foundation.

Comparative Example 1 Powder foundation (1 seri site (2 talc (3 calcium carbonate (4Titanium dioxide (Iron pentaoxide (6 trimethylolpropane Triisostearate (7) Squalane (8) Sorbitan sesquiolate (9) Preservatives (10) Oxidizing preservative (11) Fragrance (Manufacturing method) According to Example 1.

47.28 15.0 15.0 6.5 3.5 5.0 6.0 1.0 0.5 0.02 0.2 Next, the effectiveness was confirmed through a practical test. For 25 female subjects with skin prone to make-up, the foundation obtained in Example 1 was applied to one skin, and the foundation obtained in Comparative Example 1, which does not contain magnesium aluminate silicate, was applied to the other skin every day for one week. The product was applied twice and the state of rough skin was examined after use. The test results are shown in Table 1.

As is clear from the table, compared to Comparative Example 1, there were significantly more people who answered that their skin did not get rough due to make-up, which indicates that the combination of magnesium aluminate silicate is effective in preventing rough make-up. was suggested.

Table 1 Example 2 Powdered skin external preparation (1) Talc 49.95 (2) Magnesium aluminate metasilicate 42.5 (
3) Silicon dioxide 7.5 (4
) Fragrance 0.05 (manufacturing method) While stirring and mixing (1) to (3) in a blender (4
) was evenly sprayed to obtain a powdered skin preparation for external use.

Comparative Example 2 Powdered skin preparation (1) Talc (2) Mica (3) Silicon dioxide (4) Granular cellulose (5) Fragrance (Manufacturing method) According to Example 2.

49.95 7.5 7.5 35.0 0.05 The powdered skin external preparation of Comparative Example 2 was applied to the face for three months to examine its effect on improving inflammation induced by acne. The test results are shown in Table 2.

From the same table, more than 80% more people answered that "inflammation was clearly improved" and "inflammation was slightly improved" in Example 2 compared to Comparative Example 2, and the combination of magnesium aluminate metasilicate It was suggested that it is more effective against inflammation induced by acne.

Next, we confirmed the effectiveness through actual use tests. Example 3 Compact-shaped deodorant powder (1) Magnesium aluminate silicate The powdered skin external preparation obtained in Example 2 and mica were mixed in place of magnesium aluminate metasilicate for 20 test subjects suffering from acne. 15.0 (2) Magnesium metasilicate aluminate 15.0 (3) Mica 30.0
(4) Zinc milliste h io,
.

(5) Talc 2o, 0
(6) Liquid paraffin 10.0
(Manufacturing method) (1) to (5) are mixed in a Henschel mixer, and after adding component (6) to this mixture, it is pulverized with a 58P pulverizer (micron for wires), and this is press-molded into a medium plate. A compact deodorant powder according to the present invention was obtained.

Comparative Example 3 Compact deodorant powder (1) Talc 30.0 (2) Mica 30.0 (3) Zinc myristate 10.0 (4) Talc 20.
0(5) Liquid paraffin 10.
0 (Production method) Same as Example 3.

Next, we confirmed the effectiveness through actual use tests. Using 15 male subjects who had armpit odor and were prone to inflammation in their armpit skin, the compacted deodorant powder of Example 3 was applied to one armpit and the compacted deodorant of Comparative Example 3 was placed under the other armpit. Apply the powder twice a day for a week,
The anti-inflammatory effect and deodorizing effect on the skin were investigated. The test results are shown in Tables 3 and 4.

From the same table, it was revealed that, compared to Comparative Example 3, Example 3 had a better skin inflammation prevention effect and was also superior in deodorizing effect.

Table 4 Example 4 Ointment (1) Ceresin (2) Liquid paraffin (3) POE (10 moles added) Monooleate (4) Glycerin monostearate (5 Petrolatum (6) Magnesium metasilicate aluminate (7 Purified) Water (8 propylene glycol (manufacturing method) (1) to (5) mixed and dissolved at 70°C and oil phase), 20.
0 18.0 0.25 0.25 35.0 5.0 17.5 4.0 Disperse (6) in this. (8) was dissolved in (7), maintained at 70°C, added to the oil phase, and homogeneously emulsified using a homomixer, followed by cooling to obtain an ointment.

The ointment obtained in Example 4 was more effective in improving rough skin in actual use than an ointment containing kaolin instead of magnesium aluminate metasilicate.

Example 5 Lotion (1) Ethanol 15.0
(2) Hyaluronic acid 4.0 (
3) Magnesium aluminate silicate 4.0 (4
) Kaolin 0.5 (5)
Camphor (appropriate amount) (6) Fragrance (appropriate amount) (7) Purified water
Residue (manufacturing method) A lotion was obtained by a conventional method.

The lotion according to this example was excellent in suppressing the stickiness of the skin caused by sebum and improving skin inflammation.

It was highly effective.

Example 6 Cream (1) Cetostearyl alcohol 3.5 (
2) Squalane 20.0 (
3) Beeswax 3.0 (4
) Lanolin 5.0 (5
) Ethylparaben 0.3(6)
P OE (20 mol addition) Sorbitan monooleate 2.0 (7 Stearic acid monoglyceride 2.0 (8
Magnesium aluminate metasilicate 2.5 (9 Magnesium aluminate silicate 2.5 (10) Flavor bentonite 0.1 (111,3-
Butylene glycol 5.0 (12) Glycerin 5.0 (13) Purified water
49.1 (Production method) A cream was obtained by a conventional method.

Example 7 The cream according to this example improves rough skin.
Baby powder (1 talc 80.0 (
2 Calcium carbonate 17.0 (3 Starch 0.5 (4 Magnesium aluminate silicate 2.0 (5 Fungicide)
0.3 (6 preservatives
0.2 (Production method) Baby powder was obtained by a conventional method.

The baby powder according to this example was excellent in eliminating body odor and making it difficult to develop heat rash.

Example 8 Roll-on deodorant (1) Purified water (2) Ethanol (3) Sorbit (4) Magnesium metasilicate aluminate (manufacturing method) 71.0 20.0 4.0 5.0 A roll-on deodorant was obtained by a conventional method.

The roll-on deodorant according to this example had a light feeling on use, was particularly effective in suppressing itching in the armpits, and was also found to have a deodorizing effect.

Example 9 Lipstick (1) Magnesium aluminate silicate (2) Red No. 202 (3) Red No. 204 (4) Red No. 223 (5) Ceresin (6) Beeswax (7) Cetyl alcohol (8) Squirrel wax (9) ) Carnauba wax (10) Liquid paraffin (11) Liquid lanolin (12) Butyl stearate (13) Sorbitan sesquioleate 4.5 0.5 2.0 0.05 15.0 10.0 5.0 4. 0 1.0 20.95 20.0 15.0 2.0 (14) Fragrance Appropriate amount (
15) Antioxidant Appropriate amount (manufacturing method) A lipstick was obtained by a conventional method.

The lipstick according to this example prevented chapped lips and had good makeup retention.

Example 10 Stick eyeshadow (1) Ultramarine (2) Talc (3) Magnesium aluminate metasilicate (4) Pearl pigment (5) Carnauba wax (6) Solid paraffin (7) Lanolin derivative (8) Squalane (9) Glyceryl Tri-2-ethylhexanoate (10) Sorbitan sesquioleate 12.0 4.0 5.0 17.0 10.0 5.0 5.0 21.0 20.0 1.0 (11) Fragrance Appropriate amount (Manufacturing method) A stick eyeshadow was obtained by a conventional method.

The stick eyeshadow according to this example was excellent in suppressing oil floating and suppressing skin inflammation.

Example 11 A shoe insole was obtained by filling the epithelial part of the insole with magnesium aluminate silicate.

When the resulting shoe pads were used by people with sebaceous disease, it suppressed itching and skin inflammation that occurred on the feet, and it was also found to have a sufficient deodorizing effect.

Example 12 Paper Diaper Magnesium aluminate metasilicate was compounded into a water-absorbing polymer for a paper diaper to obtain a paper diaper.

The resulting paper diapers have excellent deodorizing effects and can be used for long periods of time.
It was hard to get stuffy and was effective in preventing heat rash.

Example 13 Feminine sanitary product Magnesium aluminate silicate was dispersed on the surface of a water-absorbing polymer, and a cloth was placed over the dispersion to fix the powder, thereby obtaining a feminine sanitary product.

The obtained sanitary product had a deodorizing effect and was excellent in suppressing rough skin.

Example 14 Solid powder external skin preparation (1) Talc (2) Magnesium stearate (3) Magnesium aluminate silicate (4) Spherical polyethylene (5) Fragrance (6) Bactericide 19.8 5.0 35. 0 40.0 0.1 0.1 (Production method) Spray (5) uniformly while stirring and mixing (1) to (4) and (6) in a blender, and mold this into a medium plate to solidify. A powdered skin preparation for external use was obtained.

Comparative Example 5 Solid powder external skin preparation (1 talc 19.8 (2
Magnesium stearate 5.0 (3 Magnesium aluminate silicate 35.5 (4) Spherical polyethylene 40.0 (5 Fragrance
0.1 (6 fungicide
0.1 (Production method) According to Example 14.

Next, we confirmed the effectiveness through actual use tests. 15 subjects suffering from rough skin were given 3 doses of the solid powdered external preparation for skin obtained in Example 14 and the solid powdered external preparation for skin that did not contain magnesium aluminate silicate as shown in Comparative Example 5. It was applied to the face to examine its effect on preventing rough skin. The test results are shown in Table 2.

From the same table, compared to Comparative Example 5, in Example 14, more than 50% more people answered that "rough skin was clearly improved" and "rough skin was slightly improved", and magnesium aluminate silicate did not improve skin roughness. It was suggested that the results were better than that of the previous model.

Example 15 Cleansing cream (1) Setanol (2) Peace wax (3) Stearic acid (4) Vaseline (5) Squalane 2.0 2.0 3.0 8.0 37.0 (6) Isopropyl myristate 10. 0(7) P.O.
P (20 mol addition) sorbitan laurate
2.5 (8) Glycerin monostearate 2.5 (9) Ethylparaben 0.3 (10) Fragrance
0.2 (11) Glycerin 2.0 (12) Propylene glycol 5.0 (13) Purified water 20.4 (14) Potassium hydroxide 0.1 (15) Magnesium metasilicate aluminate 5.0 (Production method) ( 1) to (10) and (11) to (14) each at 7
After heating to 0° C. to dissolve, add to the melts of (11) to (14). After emulsifying using an emulsifying machine, the mixture was cooled to a linear temperature of 30°C using a heat exchanger, and then filled into a container.

Comparative Example 6 Cleansing Cream (1) Setanol 2.0 (
2) Peace wax 2.0 (
3) Stearic acid 3.0 (4
) Vaseline 8.0 (5
) Squalane 37.0 (6
) Isopropyl myrite) 10.0 (
7) POP (20 mol addition) Sorbitan laurate 2.5 (8) Glycerin monostearate 2.5 (9) Ethyl paraben 0.3 (10) Fragrance
0.2 (11) Glycerin 2.0 (12) Propylene glycol 5.0 (13) Purified water 20.4 (14) Potassium hydroxide 0.1 (15) Sericite 5.0 Next, effects from actual use tests We have confirmed the following. For 30 test subjects suffering from acne, 15 test subjects received the cleansing cream obtained in Example 15, to which magnesium aluminate metasilicate was not added. The cleansing cream of Comparative Example 6 was used by 15 other test subjects twice a day for one month, and the effectiveness of improving inflammation induced by acne was visually judged by a professional judge.

The test results are shown in Table 8.

As is clear from the table, compared to the comparative example, the example had "clearly improved inflammation" and "inflammation was slightly improved"
More than 70% of respondents answered that magnesium aluminate metasilicate is effective against inflammation induced by acne.

Example 16 Deodorant spray (1) Freon 11 76.8 (2) n-butane (3) Magnesium aluminate silicate (4) Magnesium aluminate metasilicate (5) Isopropyl myristate (6) Tetra-2-ethyl Diglycerol hexanoate Sorpitan 19.2 1.5 1.5 0.5 0.5 (Production method) After mixing (3) to (6) in a kneader, fill it into a spray area and roughly (1 ) and (2) to obtain a deodorizing spray.

Comparative Example 7 Deodorant spray (1) Freon 11 (2) n-butane (3) Talc (4) Isopropyl myristate (5) Tetra-2-ethylhexanoic acid diglycerol sorbitan 76.8 19.2 3.0 0.5 (Manufacturing method) This is based on Example 16.

Next, we confirmed the effectiveness through actual use tests. Tests were conducted on the skin inflammation improving effect and deodorizing effect of the deodorant spray of the present invention using 20 male subjects suffering from skin inflammation and foot odor due to sebum. One foot of the subject was treated with the deodorant spray of Example 16, and the other foot was treated with one dose of the deodorant spray of Comparative Example 7.
The product was used twice a day for two weeks, and its skin inflammation-improving effect and deodorizing effect were investigated.

The test results are shown in Tables 9 and 10.

As is clear from the same table, compared to Comparative Example 7, Example 6 had an excellent effect on improving skin inflammation and also had a good deodorizing effect.

(Left below) Example 17 Pack (1) Polyvinyl alcohol (2) Polyethylene glycol 15.0 3.0 (3) Propylene glycol 7.0 (
4) Ethanol 10.0 (
5) Magnesium aluminate silicate 5.0 (6)
) Magnesium metasilicate aluminate 5.0 (7)
Methylparaben 0.05 (8)
Fragrance 0.15 (9)
Purified water 54.8 (Production method) Add (2), (3), and (7) to (9) and dissolve. Next, (1) is added and dissolved by heating and stirring, and then (5) and (6) are dispersed.

(4) and (8) were added to this and dissolved with stirring to obtain a bag.

As a result of actual use tests, the pack obtained in Example 14 was found to be excellent in suppressing skin stickiness caused by sebum and suppressing skin inflammation.

Example 18 Calamine lotion (1) Calamine (2) Magnesium aluminate metasilicate (3) Bentonite 1.0 1.0 0.2 (4) Phenol Appropriate amount (5
) Glycerin 4.0 (6)
Purified water residue (manufacturing method) Calamine lotion was obtained by a conventional method.

The calamine lotion according to this example was excellent in suppressing skin inflammation after sunburn.

Example 19 Solid white powder (1) Talc 87.
9(2) Magnesium aluminate silicate 10.0
(3) Liquid paraffin 2.0 (
4) Flavor 0.1 (Production method) A solid white powder was obtained by a conventional method.

The solid white powder according to this example had an excellent effect of preventing rough skin.

Example 20 Deodorant stick (1) Octamethylcyclotetrasiloxane 60.0 (2) Squalane 10.0 (3) Hydrocarbon wax 10.0 (4) Magnesium aluminate metasilicate 10.0 (5) Aluminate silicate Magnesium 10.0 (Production method) A deodorant stick was obtained by a conventional method.

When the deodorant stick according to this example was applied to the armpits, it had a deodorizing effect and was excellent in preventing heat rash.

Example 21 Cleansing powder (1) Soap powder (2) Sodium N-myristoylmethyltaurate (3) Myristic acid (4) POE (20 mol addition) Cetyl ether (
5) Fragrance (6) Magnesium aluminate silicate 40.0 18.0 1.0 0.5 0.5 10.0 (7) Magnesium aluminate metasilicate 5.0 (
Manufacturing method) A cleansing powder was obtained by a conventional method.

The cleansing powder according to this example had excellent cleaning effects and was effective in preventing rough skin and acne.

Example 22 Red beni (1) Magnesium aluminate silicate 5.0 (
2) Talc 80.0 (
3) Zinc stearate 5.0 (4
) Rice starch 10.0 (5
) Pigment (appropriate amount) (6) Fragrance (appropriate amount) (7) Preservative
Appropriate amount (manufacturing method) A blusher was obtained by a conventional method.

The blusher according to this example prevented skin inflammation and had good makeup retention.

Example 23 Eyeliner (1) Iron oxide (black) 11
．． 0(2) Magnesium metasilicate aluminate 5.
0(3) Vinyl acetate resin emulsion 43.0
(4) Glycerin 5.0 (
5) POE (20 mol addition) Sorbitan monooleate ester 1.0 (6) Carboxyethylene methylcellulose (10% aqueous solution) 15.0 (
7 Acetyltributyl citrate 1.0 (8 Purified water 19.0 (9 Fragrance)
Appropriate amount (10 preservatives
Appropriate amount (manufacturing method) An eyeliner was obtained by a conventional method.

The eyeliner according to this example suppressed skin roughness and had good makeup retention.

Calamine Lotion (1) Ethanol (2) Glycerin (3) Hyaluronic Acid (4) Red Red (5) Zinc Oxide (6) Aluminum Silicate Magnesium acid (7) Phenol (8) Camphor (9) Fragrance (10) Ion-exchanged water (Production method) Calamine lotion was obtained by a conventional method.

Comparative Example 8 Calamine lotion (1) Ethanol (2) Glycerin 14.0 3.0 0.2 0.15 0.5 1.0 0.05 0.15 Appropriate amount remainder 14.0 3.0 (3 Hyaluronic acid (4 Bengala (zinc pentoxide (6 talc (7 phenol (8 camphor (9 fragrances (10) Ion exchange water (Manufacturing method) According to Example 24.

0.2 0.15 0.5 1.0 0.05 0.15 The appropriate amount of residue was more than 50% higher, and magnesium aluminate silicate was excellent in suppressing rough skin and oil floating after sunburn.

(See margin below) Next, we confirmed the effectiveness through actual use tests. summer,
The calamine lotion of Example 24 was applied to one cheek of the face of 15 female panelists who tanned for 2 hours under direct sunlight, and the calamine lotion of Comparative Example 8 was applied to the other cheek, and a puff was used immediately after the tanning was completed. 24 hours later, the condition of the skin on the cheeks was evaluated by each person. The test results are shown in Tables 11 and 12.

From the same table, compared to Comparative Example 8, those who answered that Example 24 had "less rough skin and less oily skin" Table 11 Example 25 Acne lotion (1) Thioxolone (2) Magnesium aluminate metasilicate (3) d-camphor (4 d-menthol (5) hexachlorophene (6) propylene glycol (7) ethanol (8) fragrance (9) colorant (10) ion-exchanged water (manufacturing method) Acne lotion was obtained by a conventional method.

0.01 2.0 0.02 0.05 0.01 5.0 15.0 Appropriate amount Appropriate amount Residue Comparative Example 9 Acne lotion (1) Thioxolone (2) Calcium carbonate (3) d-camphor (4) d-menthol 0.01 2.0 0.02 0.05 (5 Hexachlorophene 0.01 (6
Propylene glycol 5.0 (7) Ethanol 15.0 (8)
Appropriate amount (9 colorants
Appropriate amount (10 ion exchange water
Residue (manufacturing method) Acne lotion was obtained in the same manner as in Example 25.

It was suggested that the combination of magnesium ruminate is effective against inflammation induced by acne.

Next, we confirmed the effectiveness through actual use tests. For 25 test subjects suffering from acne, the acne lotion obtained in Example 25 was used on one cheek and the acne lotion obtained in Comparative Example 9 was used on the other cheek for one month, and the effect of improving inflammation induced by acne was evaluated. I looked into it.

The test results are shown in Table 13.

From the same table, compared to Comparative Example 9, more than 80% more people answered that "inflammation was clearly improved" and "inflammation was slightly improved" in Example 25. (1) Ethanol (2) Propylene glycol (3) Alum (4) Citric acid (5) Polyoxyethylene sorbitan monooleate (6) Fragrance (7) Magnesium aluminate silicate (8) Ion exchange water 11.0 5 .0 1.5 0.5 2.5 Appropriate amount 1.0 Residue (manufacturing method) A lotion was obtained by a conventional method.

The obtained lotion was excellent in suppressing stickiness caused by skin oil.

Example 27 Lotion (1) Potassium hydroxide (2) Glycerin (3) Ethanol (4) Ethyl paraoxybenzoate (5) Fragrance (6) Coloring agent (7) Magnesium aluminate silicate (8) Aluminate metasilicate Magnesium (9) ion exchange water (manufacturing method) A lotion was obtained by a conventional method.

0.05 10.0 15.0 0.1 Appropriate amount Appropriate amount 1.0 1.0 remainder The lotion obtained is Excellent in preventing skin irritation It was something.

Example 28 Aftershave lotion (1)
Ethanol 25.0 (2) Sorbit 2.0 (3) Hexachlorophene 0.1 (4) Menthol 0.3 (5) Aminobenzoic acid 0.2 (6) Citric acid
0.1 (7) Fragrance
Appropriate amount (8) Magnesium metasilicate aluminate (9) Ion exchange water
Residue (manufacturing method) An aftershave lotion was obtained by a conventional method.

The obtained aftershave lotion was effective in protecting the skin after shaving and preventing razor burn.

Kay Aluminum Magnesium and or mail (Manufacturing method) A serum was obtained by a conventional method.

Example 29 Beauty serum (1) Glycerin (2) Dipropylene glycol (3) Hyaluronic acid (4) Ethanol (5) Carboxyvinyl polymer (6) Potassium hydroxide (7) Sodium hexametaphosphate (8) Urocanic acid (9) ) Bantothenyl ethyl ether (10) Fragrance (11) POE (20) Octyldodecanol (12)
Methylparaben (13) EDTA・3Na・2H20 (14) Magnesium aluminate silicate (15) Magnesium aluminate metasilicate (16) Ion exchange water 8.0 5.0 0.1 5.0 0.15 0.006 0 .02 0.1 0.05 0.01 0.3 0.1 0.01 0.5 0.5 Remaining comparative example 10 Beauty serum (1) Glycerin (2) Dipropylene glycol (3) Hyaluronic acid (4) Ethanol (5) Carboxyvinyl polymer (6) Potassium hydroxide (7) Sodium hexametaphosphate (8) Urocanic acid (9) Pantothenyl ethyl ether (10) Fragrance (11) POE (20) Octyldodecanol (12)
Methylparaben (13) EDTA・3Na・2H20 (14) Talc (15) Ion exchange water (manufacturing method) 8.0 5.0 0.1 5.0 0.15 o, ooe O2O3 0,1 0,05 0,01 0,3 0,1 0,01 0,1 Residual serum was obtained by a conventional method.

Next, we confirmed the effectiveness through actual use tests. winter season,
The serum of Example 29 was applied to one cheek of the face of 1 o female subjects who are prone to rough skin, and the serum of Comparative Example 10 was applied to the other cheek for two weeks, and the skin condition of the cheek was evaluated individually. The test results are shown in Table 14.

From the same table, compared to Comparative Example 10, more than 50% more people answered that Example 29 had "less rough skin," indicating that magnesium aluminate silicate was excellent in preventing skin roughness in winter.

Example 30 Beauty essence (emulsified type) (1) Glycerin (2) Dipropylene glycol (3) Ethanol (4) Carboxyvinyl polymer (5) Potassium hydroxide (6) EDTA・3Na・2H20 (7) Sodium hexametaphosphate (8) Aloe powder (9) Fragrance (10) Methylparaben (11) Magnesium aluminate metasilicate (12)
POE (60) Hydrogenated castor oil (13) Octylmethoxycinnamic acid (14) Methylphenylpolysiloxane (15) Dimethylpolysiloxane (16) Squalane (17) D-5 (18) Ion exchange water (manufacturing method) By conventional method I got the serum.

7.0 6.0 3.0 0.1 0.03 0.01 0.02 0.2 0.01 0.1 0.9 0.5 0.5 1.0 0.5 0.5 0. 5 Remaining Comparative Example 11 Beauty serum (emulsified type) (1) Glycerin (2) Dipropylene glycol (3) Ethanol (4) Carboxyvinyl polymer (5) Potassium hydroxide (6) EDTA・3Na・2H20 (7) Hexamethalin Sodium acid (8) Aloe powder (9) Fragrance (10) Methyl paraben (11) Mica (12) POE (60) Hydrogenated castor oil (13) Octyl methoxycinnamic acid (14) Methylphenyl polysiloxane (15) Dimethyl polysiloxane (16) Squalane (17) D -5 (18) Ion exchange water 7.0 6.0 3.0 0.1 0.03 0.01 0.02 0.2 0.01 0.1 0.9 0 .5 0.5 1.0 0.5 0.5 0.5 Residue (manufacturing method) A serum was obtained by a conventional method.

Next, we confirmed the effectiveness through actual use tests. Twenty female subjects suffering from sticky sebum applied the serum of Example 30 on one cheek and the serum of Comparative Example 11 on the other cheek for one week, and each evaluated the sticky state of their sebum. .

The test results are shown in Table 15.

From the same table, compared to Comparative Example 11, more than 50% more people answered that Example 30 had "less sticky sebum," indicating that magnesium aluminate metasilicate had an excellent effect of preventing sticky sebum.

(Margin below) Table 15 Example 31 Beauty serum (1) Glycerin (2) Dipropylene glycol (3) Hyaluronic acid (4) Ethanol (5) Carboxyvinyl polymer (6) Potassium hydroxide (7) Sodium hexametaphosphate (8) Allantoin (9) Bantothenyl ethyl ether 8.0 5.0 0.1 5.0 0.15 0.006 0.02 0.1 0.05 (10) Fragrance 0.01
(11) POE (20) Octyldodecanol 0
．． 3(12) Methylparaben 0.
1 (13) EDTA・3Na・2H200,01(1
4) Magnesium aluminate silicate 1.0 (15
) Ion-exchanged water Residue (manufacturing method) A beauty serum was obtained by a conventional method.

The beauty serum according to this example was more effective in improving rough skin in actual use.

Example 32 Beauty essence (emulsified type) (1) Glycerin 7.0 (2
) Dipropylene glycol 6.0 (3) Ethanol 3.0 (4) Carboxyvinyl polymer 0.1 (5) Potassium hydroxide 0.03 (6) EDTA・3
Na・2H200,01(7) Sodium hexametaphosphate 0.02(8) Vitamin E acetate
0.2 (9 fragrances
0.01 (10 methylparaben
0.1 (11 Magnesium aluminate metasilicate 0
．． 5 (12POE (60) hydrogenated castor oil
0.5 (13 octyl methoxycinnamic acid 0.
5 (14 methyl phenyl polysiloxane 1.0 (
15 dimethylpolysiloxane 0.5 (16
Squalane 0.5 (17D-
50.5 (18 ion-exchanged water Residue (manufacturing method) A beauty serum was obtained by a conventional method.

The beauty serum according to this example was more effective in improving rough skin in actual use.

(1) Microcrystalline wax (2) Beeswax (3) Lanolin (4) Liquid paraffin (5) Sorbitan sesquioleate (6) Polyoxyethylene sorbitan monooleate (20E, 0,) (7) Aluminum stearate (8) Fragrance (9) Preservative (IO) Antioxidant (11) Glycerin (12) Magnesium aluminate silicate (13) Ion-exchanged water (Production method) A milky lotion was obtained by a conventional method.

1.0 2.0 2.0 30.0 4.0 0.2 0.4 Proper amount Proper amount Proper amount 8.0 2.0 Example 33 Emulsion Comparative Example 12 Emulsion (1) Microcrystalline wax 1.0 (2) Beeswax (3) Lanolin (4) Liquid paraffin (5) Sorbitan sesquioleate (6) Polyoxyethylene sorbitan monooleate (20E, 01) (7 Aluminum stearate (8 Fragrance (9) Preservative (10 Antioxidant) Agent (11 Glycerin (12) Mica (13) Ion-exchanged water (manufacturing method) According to Comparative Example 33.

2.0 2.0 30.0 4.0 0.2 0.4 Appropriate amount Appropriate amount Appropriate amount 8.0 2.0 Next, the effect was confirmed through a practical use test. For 30 subjects suffering from rough skin, the emulsion obtained in Example 33 was applied to one cheek of the face, and the emulsion obtained in Comparative Example 12 was applied to the other cheek for two weeks to examine the effect of improving rough skin. .

The test results are shown in Table 16.

From the same table, compared to Comparative Example 12, more than 80% more people answered that "rough skin was improved" in Example 33, suggesting that magnesium aluminate silicate is effective against rough skin.

Example 34 Emulsion (1) Squalane (2) Vaseline (3) Beeswax (4) Sorbitan sesquioleic acid ester 5.0 2.0 0.5 0.8 (5) 20 (EO) Polyoxyethylene olein ether (6 Fragrance (7 Ethyl parapene (8) Vitamin E acetate (9) Propylene glycol (10) Hyaluronic acid (11) Ethanol (12) Carboxyvinyl polymer 1.0% aqueous solution (13) Potassium hydroxide (14) Magnesium aluminate metasilicate (15) Magnesium aluminate silicate (16') ion-exchanged water (manufacturing method) A milky lotion was obtained by a conventional method.

1.2 0.5 Appropriate amount Appropriate amount 5.0 0.5 5.0 20.0 0.1 0.5 0.5 Remaining comparative example 13 Emulsion (1) Squalane (2) Vaseline 5.8 2.0 (3 ) Beeswax (4) Sorbitan sesquioleate (5) 20 (EO) polyoxyethylene olein ether (6) Fragrance (7) Ethylparaben (8 Vitamin E acetate (9 Propylene glycol (10) Hyaluronic acid (11 Ethanol (12 Carboxyl) Vinyl polymer 1.0% aqueous solution (13) Potassium hydroxide (14) Talc (15) Ion exchange water (Production method) A milky lotion was obtained by a conventional method.

0.5 0.8 1゜2 0.5 Appropriate amount Appropriate amount 5.0 0.5 5.0 20.0 0.1 0.5 Residue Next, the effect was confirmed by a practical test. To 18 test subjects suffering from acne, the emulsion obtained in Example 34 was applied to one cheek of the face and the emulsion obtained in Comparative Example 13 to the other cheek for one month, and the results were shown to be effective against acne. We investigated its effectiveness in improving inflammation.

The test results are shown in Table 17.

From the same table, compared to Comparative Example 13, more than 80% more people answered that "inflammation was improved" in Example 34. It was suggested that it is effective against.

Example 35 Emulsion (1) Stearic acid (2) Setanol 2.0 1.5 (3) Vaseline 3.0 (
4) Lanolin alcohol 2.0 (5)
Liquid paraffin 10.0(6)E
, 0, (10) Polyoxyethylene monooleate ether 2.0 (7) Fragrance 0.5 (8
) Vitamin E acetate (9) Methylparaben (10) Glycerin 3.0 (11) Propylene glycol 5.0 (12) Triethanolamine 1.0 (13) Magnesium aluminate silicate 0.4 (14) Metasilicic acid Magnesium aluminate 0.4 (15) Ion exchange water
Residue (manufacturing method) A milky lotion was obtained by a conventional method.

The emulsion according to this example prevents skin roughness in actual use,
It was effective in keeping the skin moist.

Example 36 Emulsion (1 Liquid paraffin 7.0 (2 Lanolin 3.0 (3 Oleic acid 3.0) (4 Triethanolamine 1.5 (5 Ethylparaben)
Appropriate amount (6) Fragrance
Appropriate amount (7) Magnesium aluminate metasilicate 1.0 (8) Ion exchange water
Residue (manufacturing method) A milky lotion was obtained by a conventional method.

The emulsion according to this example had an excellent effect of improving rough skin in actual use.

Example 37 Deodorizing spray (1) LPG” (2) Isopentane 59.5 35.8 (3) Magnesium metasilicate aluminate 2.0 (4
) Magnesium aluminate silicate 1.3 (5) Isopropyl myristate 0.9 (6) Tetra-2-ethylhexyate diglycerol sorbitan 0.5 *Propane (43%)/isobutane (16%)/n-butane ( 41%) (Manufacturing method) A deodorizing spray was obtained by a conventional method.

Comparative example 14 Deodorizing spray (1) LP G” 5
9.5(2) Isopentane 35
．． 5(3) Evening/Ruku 3
．． 3(4) Isopropyl myristate 0.9
(5) Tetra-2-ethylhexyl diglycerol sorbitan 0.5 *Propane (43%)/isobutane (16%)/n-butane (41X) (Production method) Obtain deodorizing spray in the same manner as in Example 37 Ta.

Table 18 Next, the effects were confirmed through actual use tests. Using 30 male subjects suffering from skin inflammation and foot odor due to sebaceous disease,
Tests were conducted on the skin inflammation improving effect and deodorizing effect of the deodorant spray of the present invention.

The deodorant spray of Example 37 was applied to one foot of the test subject, and the deodorant spray of Comparative Example 14 was applied to the other foot twice a day for two weeks to examine the effect of improving skin inflammation and deodorizing effect.

The test results are shown in Tables 18 and 19.

As is clear from the table, Example 37 had a better skin inflammation improving effect and deodorizing effect than Comparative Example 14.

(Left below) Example 38 Compact deodorant powder (1) Magnesium aluminate silicate 30 (2) Magnesium aluminate metasilicate 30 (3) Zinc myristate 10 (4) Talc
20(5) Liquid paraffin
10 (Production method) Components (1) to (4) are mixed in a Henschel mixer, and component (5) is added to this mixture. After mixing, 5
The powder was pulverized with an 8P pulperizer (wire micron) and press-molded into a medium plate to obtain a compact deodorant powder according to the present invention.

Comparative Example 15 Compact deodorant powder (1) Silicic anhydride 60 (2) Zinc myristate 10 (3) Talc
20(4) Liquid paraffin
10 (Production method) According to Example 38.

Using 20 male subjects, the compact deodorant powder of Example 38 was placed under one armpit and the compact deodorant powder of Comparative Example 15 was placed under the other armpit twice a day.
The product was used repeatedly for one week, and its anti-inflammation and deodorizing effects on the skin were examined. The test results are shown in Tables 19 and 20.

From the same table, it was revealed that, compared to Comparative Example 15, Example 38 had a better skin inflammation prevention effect and was also superior in deodorizing effect.

Next, we confirmed the effectiveness through actual use tests. Table 20 Example 39 Roll-on deodorant (1) Sugar ice cream (2) Ethanol (3) Sorbit (4) Magnesium aluminate silicate (manufacturing method) Mix ingredients (1) to (4) and place in a roll-on container,
A roll-on deodorant was prepared.

When the resulting roll-on deodorant was used on the armpits, it had a deodorizing effect and also had the effect of suppressing heat rash.

Example 40 Baby powder (1) Magnesium aluminate metasilicate (2) Spherical polyethylene (3) Fragrance (manufacturing method) Components (1) to (3) were mixed in a Nauta mixer to obtain baby powder.

The obtained baby powder suppressed the floating of oil on the skin and was effective in preventing heat rash.

Example 41 Deodorant stick (1) Octamethylcyclotetrasiloxane 60.0 (2) Squalane 10.0
(3) Hydrocarbon wax 10.0 (
4) Magnesium aluminate silicate 10.0 (
5) Magnesium metasilicate aluminate 10.0 (manufacturing method) Components (1) to (5) were heated and mixed and filled into a container to obtain a deodorant stick.

The obtained deodorant stick suppressed rough skin and gave a firm feeling to the skin.

Example 42 Shoe insole The epithelial part of the insole was filled with magnesium aluminate metasilicate to obtain a shoe insole.

When the resulting shoe pads were used by people with sebaceous disease, they suppressed itching and skin inflammation that occur on the feet, and had sufficient deodorizing effects.

Example 43 Paper Diaper Magnesium aluminate silicate was compounded into a water-absorbing polymer for a paper diaper to obtain a paper diaper.

The resulting paper diapers have excellent deodorizing effects and can be used for long periods of time.
It was difficult to get heat rash.

Example 44 Feminine sanitary product Magnesium aluminate metasilicate was dispersed on the surface of a water-absorbing polymer, and a cloth was placed over the dispersion to fix the powder to obtain a feminine sanitary product.

The obtained sanitary products had excellent deodorizing effects and were effective in suppressing skin inflammation.

[Effects of the Invention] Since the present invention is configured as described above, it produces the effects described below.

Magnesium aluminate silicate according to claim 1 and/or
Or, according to a lipid peroxide adsorbent containing magnesium aluminate metasilicate as an active ingredient, since it contains magnesium aluminate silicate and/or magnesium aluminate metasilicate, its ability to adsorb lipid peroxide can cause rough skin, Skin inflammation, itching, heat rash, acne, etc. can be prevented or suppressed.

Magnesium aluminate silicate according to claim 2 and/or
Or, according to a skin external preparation containing magnesium aluminate metasilicate as an active ingredient, since it contains magnesium aluminate silicate and/or magnesium aluminate metasilicate, its ability to adsorb lipid peroxide causes rough skin and skin irritation. Inflammation, itching, heat rash, acne, etc. can be prevented or suppressed.

Magnesium aluminate silicate according to claim 3 and/or
Or, according to a lotion containing magnesium aluminate metasilicate as an active ingredient, since it contains magnesium aluminate silicate and/or magnesium aluminate metasilicate, its ability to adsorb lipid peroxide can cause rough skin and skin inflammation. , itching, heat rash, acne, etc. can be prevented or suppressed.

Magnesium aluminate silicate according to claim 4 and/or
Or, according to a beauty serum containing magnesium aluminate metasilicate as an active ingredient, since it contains magnesium aluminate silicate and/or magnesium aluminate metasilicate, its ability to adsorb lipid peroxide can cause rough skin and skin inflammation. , itching, heat rash, acne, etc. can be prevented or suppressed. According to the emulsion containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient according to claim 5, since it contains magnesium aluminate silicate and/or magnesium aluminate metasilicate, Oxidized lipid adsorption ability can prevent or suppress rough skin, skin inflammation, itching, heat rash, acne, etc. According to the deodorant containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient according to claim 6, since it contains magnesium aluminate silicate and/or magnesium aluminate metasilicate, Due to its ability to adsorb lipid peroxide, it has an excellent deodorizing effect.

Claims (6)

[Claims] (1) A lipid peroxide adsorbent containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient. (2) A skin external preparation containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient. (3) A lotion containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient. (4) A beauty serum containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient. (5) An emulsion containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient. (6) A deodorant containing magnesium aluminate silicate and/or magnesium aluminate metasilicate as an active ingredient.