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JPH08507066A - 治療用ペプチド含有のミクロエマルジョン - Google Patents

治療用ペプチド含有のミクロエマルジョン

Info

Publication number
JPH08507066A
JPH08507066A JP6519110A JP51911094A JPH08507066A JP H08507066 A JPH08507066 A JP H08507066A JP 6519110 A JP6519110 A JP 6519110A JP 51911094 A JP51911094 A JP 51911094A JP H08507066 A JPH08507066 A JP H08507066A
Authority
JP
Japan
Prior art keywords
microemulsion
medium chain
fatty acid
hlb surfactant
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6519110A
Other languages
English (en)
Japanese (ja)
Inventor
コンスタンティニデス，パナイオティス・ペリクレウス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of JPH08507066A publication Critical patent/JPH08507066A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP6519110A 1993-02-17 1994-02-17 治療用ペプチド含有のミクロエマルジョン Pending JPH08507066A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1860993A 1993-02-17 1993-02-17
US08/018,609 1993-02-17
PCT/US1994/001678 WO1994019001A1 (fr) 1993-02-17 1994-02-17 Micro-emulsions comprenant des peptides therapeutiques

Publications (1)

Publication Number Publication Date
JPH08507066A true JPH08507066A (ja) 1996-07-30

Family

ID=21788831

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6519110A Pending JPH08507066A (ja) 1993-02-17 1994-02-17 治療用ペプチド含有のミクロエマルジョン

Country Status (3)

Country Link
EP (1) EP0684833A4 (fr)
JP (1) JPH08507066A (fr)
WO (1) WO1994019001A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011504871A (ja) * 2007-06-01 2011-02-17 ノボ・ノルデイスク・エー／エス 固体又は半固体担体中にペプチド薬剤を含む自然に分散可能なプレコンセントレイト
US9481721B2 (en) 2012-04-11 2016-11-01 Novo Nordisk A/S Insulin formulations
US9688737B2 (en) 2008-03-18 2017-06-27 Novo Nordisk A/S Protease stabilized acylated insulin analogues
US10265385B2 (en) 2016-12-16 2019-04-23 Novo Nordisk A/S Insulin containing pharmaceutical compositions
JP2019514856A (ja) * 2016-04-21 2019-06-06 ユニリーバー・ナームローゼ・ベンノートシヤープ 脂肪酸及びアミノ酸塩のｎ−アシル誘導体を含む新規なナノエマルジョン
JP2019514857A (ja) * 2016-04-21 2019-06-06 ユニリーバー・ナームローゼ・ベンノートシヤープ Ｎ−アシルアミノ酸塩を含む新規ナノエマルションおよび製造方法
JP2019517998A (ja) * 2016-04-21 2019-06-27 ユニリーバー・ナームローゼ・ベンノートシヤープ 低圧下における小液滴エマルジョンの製造方法

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
CA2160681A1 (fr) * 1993-04-19 1994-10-27 Masao Takahashi Preparation d'une microemulsion renfermant une substance legerement absorbable
EP0736041B1 (fr) * 1993-11-17 2006-02-08 Athena Neurosciences, Inc. Liquide transparent permettant l'administration de medicaments encapsules
CA2285389C (fr) 1997-03-31 2008-12-30 Neorx Corporation Inhibiteur therapeutique des cellules des muscles lisses de la paroi vasculaire
DE19716953B4 (de) * 1997-04-22 2006-02-09 Forschungszentrum Jülich GmbH Verfahren zur Sanierung von mit Schadstoff kontaminiertem Boden und bikontinuierliche Mikroemulsion
DE10013796A1 (de) * 2000-03-20 2001-09-27 Kaercher Gmbh & Co Alfred Dekontaminations-Zusammensetzung sowie Emulsionen hieraus
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
CN107496912B (zh) * 2017-04-14 2021-06-29 郑振宜 一种乙肝病毒抗原肽联合肝癌细胞抗原信息的抗原提呈信号群及其应用
CN109010117B (zh) * 2018-07-10 2021-05-25 山西医科大学 一种具有滋润保湿作用的微乳凝胶护唇啫喱及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
IE60024B1 (en) * 1987-02-03 1994-05-18 Stiefel Laboratories Ltd Microemulsions
DE3908047A1 (de) * 1989-03-13 1990-09-20 Desitin Arzneimittel Gmbh Hochdisperse pharmazeutische zusammensetzung
US5110606A (en) * 1990-11-13 1992-05-05 Affinity Biotech, Inc. Non-aqueous microemulsions for drug delivery

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011504871A (ja) * 2007-06-01 2011-02-17 ノボ・ノルデイスク・エー／エス 固体又は半固体担体中にペプチド薬剤を含む自然に分散可能なプレコンセントレイト
US9688737B2 (en) 2008-03-18 2017-06-27 Novo Nordisk A/S Protease stabilized acylated insulin analogues
US10259856B2 (en) 2008-03-18 2019-04-16 Novo Nordisk A/S Protease stabilized acylated insulin analogues
US9481721B2 (en) 2012-04-11 2016-11-01 Novo Nordisk A/S Insulin formulations
JP2019514856A (ja) * 2016-04-21 2019-06-06 ユニリーバー・ナームローゼ・ベンノートシヤープ 脂肪酸及びアミノ酸塩のｎ−アシル誘導体を含む新規なナノエマルジョン
JP2019514857A (ja) * 2016-04-21 2019-06-06 ユニリーバー・ナームローゼ・ベンノートシヤープ Ｎ−アシルアミノ酸塩を含む新規ナノエマルションおよび製造方法
JP2019517998A (ja) * 2016-04-21 2019-06-27 ユニリーバー・ナームローゼ・ベンノートシヤープ 低圧下における小液滴エマルジョンの製造方法
US12453680B2 (en) 2016-04-21 2025-10-28 Conopco, Inc. Nanoemulsions comprising fatty acid and N-acyl derivatives of amino acid salt
US10265385B2 (en) 2016-12-16 2019-04-23 Novo Nordisk A/S Insulin containing pharmaceutical compositions
US10596231B2 (en) 2016-12-16 2020-03-24 Novo Nordisk A/S Insulin containing pharmaceutical compositions

Also Published As

Publication number Publication date
EP0684833A4 (fr) 1996-09-11
EP0684833A1 (fr) 1995-12-06
WO1994019001A1 (fr) 1994-09-01

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