JPH0840923A - Nutrient-supplying agent - Google Patents
Nutrient-supplying agentInfo
- Publication number
- JPH0840923A JPH0840923A JP6194620A JP19462094A JPH0840923A JP H0840923 A JPH0840923 A JP H0840923A JP 6194620 A JP6194620 A JP 6194620A JP 19462094 A JP19462094 A JP 19462094A JP H0840923 A JPH0840923 A JP H0840923A
- Authority
- JP
- Japan
- Prior art keywords
- agent
- mixture
- mineral
- nutrient
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 235000004279 alanine Nutrition 0.000 description 1
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- VCPUQYKWJRESOC-VJXVFPJBSA-N aspalathin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=C(O)C(C(=O)CCC=2C=C(O)C(O)=CC=2)=C1O VCPUQYKWJRESOC-VJXVFPJBSA-N 0.000 description 1
- VCPUQYKWJRESOC-UHFFFAOYSA-N aspalathine Natural products OC1C(O)C(O)C(CO)OC1C1=C(O)C=C(O)C(C(=O)CCC=2C=C(O)C(O)=CC=2)=C1O VCPUQYKWJRESOC-UHFFFAOYSA-N 0.000 description 1
- 201000008937 atopic dermatitis Diseases 0.000 description 1
- 235000013734 beta-carotene Nutrition 0.000 description 1
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 description 1
- 239000011648 beta-carotene Substances 0.000 description 1
- 229960002747 betacarotene Drugs 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 235000020279 black tea Nutrition 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 150000001728 carbonyl compounds Chemical class 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 description 1
- 229940125904 compound 1 Drugs 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 229960003067 cystine Drugs 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 231100000517 death Toxicity 0.000 description 1
- 238000010908 decantation Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 230000002900 effect on cell Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- IVTMALDHFAHOGL-UHFFFAOYSA-N eriodictyol 7-O-rutinoside Natural products OC1C(O)C(O)C(C)OC1OCC1C(O)C(O)C(O)C(OC=2C=C3C(C(C(O)=C(O3)C=3C=C(O)C(O)=CC=3)=O)=C(O)C=2)O1 IVTMALDHFAHOGL-UHFFFAOYSA-N 0.000 description 1
- 210000003722 extracellular fluid Anatomy 0.000 description 1
- XUFQPHANEAPEMJ-UHFFFAOYSA-N famotidine Chemical compound NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 XUFQPHANEAPEMJ-UHFFFAOYSA-N 0.000 description 1
- 229960001596 famotidine Drugs 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 229940093915 gynecological organic acid Drugs 0.000 description 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 description 1
- 210000002977 intracellular fluid Anatomy 0.000 description 1
- ODBRNZZJSYPIDI-VJXVFPJBSA-N isoorientin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=C(OC(=CC2=O)C=3C=C(O)C(O)=CC=3)C2=C1O ODBRNZZJSYPIDI-VJXVFPJBSA-N 0.000 description 1
- UYJGIAWJIRZBNU-UHFFFAOYSA-N isoorientin Natural products OCC1OC(C(O)C(O)C1O)c2cc(O)c(O)c3C(=O)C=C(Oc23)c4ccc(O)c(O)c4 UYJGIAWJIRZBNU-UHFFFAOYSA-N 0.000 description 1
- 235000015110 jellies Nutrition 0.000 description 1
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- 239000011572 manganese Substances 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
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- 238000000034 method Methods 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 description 1
- 235000005875 quercetin Nutrition 0.000 description 1
- 229960001285 quercetin Drugs 0.000 description 1
- FDRQPMVGJOQVTL-UHFFFAOYSA-N quercetin rutinoside Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 FDRQPMVGJOQVTL-UHFFFAOYSA-N 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 235000005493 rutin Nutrition 0.000 description 1
- ALABRVAAKCSLSC-UHFFFAOYSA-N rutin Natural products CC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5 ALABRVAAKCSLSC-UHFFFAOYSA-N 0.000 description 1
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- 229960004555 rutoside Drugs 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- BWMISRWJRUSYEX-SZKNIZGXSA-N terbinafine hydrochloride Chemical compound Cl.C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 BWMISRWJRUSYEX-SZKNIZGXSA-N 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019163 vitamin B12 Nutrition 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 235000019158 vitamin B6 Nutrition 0.000 description 1
- 239000011726 vitamin B6 Substances 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
【0001】[0001]
【産業上の利用分野】本発明は、栄養補助剤に関し、さ
らに詳しくは、アスパラサス・リネアリスの含有成分か
ら生命が誕生した原始の海のミネラル組成比率と同じミ
ネラル成分を抽出し、アミノ酸混合物とビタミン混合物
を加えてなる栄養補助剤に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a nutritional supplement, and more specifically, it extracts from an Aspalathus linearias mineral component the same mineral component as that of the primitive sea in which life was born, to obtain an amino acid mixture. The present invention relates to a nutritional supplement containing a vitamin mixture.
【0002】[0002]
【従来の技術】従来より、機能性食品、健康食品、健康
補助剤、栄養剤としては多くの製品が知られている。2. Description of the Related Art Conventionally, many products are known as functional foods, health foods, health supplements and nutritional supplements.
【0003】[0003]
【発明が解決しようとする課題】しかし、これらの製品
は効力の疑わしいものや、効力の弱いものがほとんど
で、効果があるものは副作用が生じるため、健康を維持
し、成人病、老年病を予防あるいは改善することは難し
く、また、効果が薄いため効果を得るのに長時間を要す
る欠点があった。However, most of these products have suspicious efficacy or weak efficacy, and those that are effective have side effects, so maintain health and prevent adult diseases and geriatric diseases. It is difficult to prevent or improve, and there is a drawback that it takes a long time to obtain the effect because the effect is weak.
【0004】本発明は、副作用が少なく、細胞機能を活
発にして身体のホメオスタシスを維持して健康を維持
し、成人病、老年病を予防するのに強い効力を有する人
を始めとした哺乳動物の栄養補助剤の提供を目的とす
る。The present invention provides mammals including humans, which have few side effects, have a strong effect on cell homeostasis, maintain homeostasis of the body and maintain health, and prevent adult diseases and senile diseases. The purpose is to provide nutritional supplements for.
【0005】[0005]
【課題を解決するための手段】そこで、本発明者は前記
課題を解決するため鋭意研究を重ねた結果、細胞が最も
生育しやすくするためには生命が誕生した原始の海と類
似のミネラル組成比率を用いるこに着目し、このミネラ
ル組成比率をアスパラサス・リネアリスの抽出液から得
ることを見出し、原始の海と同じミネラル組成で、かつ
体液(細胞内液+細胞外液)と同じミネラル組成比率を
持ち、これと、アミノ酸混合物、ビタミン、さらに体内
の活性酸素を消去・除去するスカベンジ作用および/ま
たは抗酸化能を有する物質、かつ、フェノール化合物、
及びフラボノイド、糖化フラボノイド等の糖化合物を含
有する組成物が、広範な疾患に対して優れた効果を有
し、かつ副作用がなく安全且つ迅速に健康を維持し、弱
った体力を回復し、かつ成人病と老人病の改善と治療が
でき、前記課題が解決できるとの知見を得て本発明を完
成した。The inventors of the present invention have conducted extensive studies to solve the above problems, and as a result, in order to make the cells grow most easily, a mineral composition similar to that of the primitive sea in which life was born was created. Focusing on the use of ratio, we found that this mineral composition ratio was obtained from the extract of Aspalathus linealis, and it has the same mineral composition as the original sea and the same mineral composition as body fluid (intracellular fluid + extracellular fluid). A substance having a ratio, an amino acid mixture, a vitamin, a substance having a scavenging action for eliminating / removing active oxygen in the body and / or an antioxidant ability, and a phenol compound,
And flavonoids, compositions containing sugar compounds such as glycated flavonoids have excellent effects against a wide range of diseases, and maintain safe and quick health without side effects, recover weak physical strength, and The present invention has been completed based on the knowledge that adult diseases and geriatric diseases can be improved and treated and the above problems can be solved.
【0006】本発明の有効成分は、原始の海と類似のミ
ネラル組成比率を持つミネラル混合物である。このミネ
ラル混合物は、アスパラサス・リネアリスの抽出液から
得るのが好ましい。The active ingredient of the present invention is a mineral mixture having a mineral composition ratio similar to that of the primitive sea. This mineral mixture is preferably obtained from the extract of Aspalathus linealis.
【0007】アミノ酸混合物に加えられるアミノ酸とし
ては、フェニルアラニン、リジン、スレオニン、トリブ
トファン、バリン、イソロイシン、ロイシン、メチオニ
ン、グルタミン酸、アスパラギン酸、アルギニン、ヒス
チジン、チロシン、アラニン、グリシン、ブロリン、セ
リン、シスチン、タウリンなどより選ばれた1種または
これらの混合物が挙げられる。Amino acids added to the amino acid mixture include phenylalanine, lysine, threonine, tributophan, valine, isoleucine, leucine, methionine, glutamic acid, aspartic acid, arginine, histidine, tyrosine, alanine, glycine, brolin, serine, cystine, taurine. And the like, or a mixture thereof.
【0008】ビタミンとしては、ビタミンB1、ビタミ
ンB2、ビタミンB6、ビタミンB12、コリン、イノ
シトール、ビオチン、葉酸、ビタミンC、ビタミンA、
ビタミンD、ビタミンEなどより選ばれた1種またはこ
れらの混合物が挙げられる。As vitamins, vitamin B1, vitamin B2, vitamin B6, vitamin B12, choline, inositol, biotin, folic acid, vitamin C, vitamin A,
One kind or a mixture thereof selected from vitamin D, vitamin E and the like can be mentioned.
【0009】また、本発明は、リン、鉄、マグネシウ
ム、銅、亜鉛、マンガン、セレン、ルビジウム、フッ素
等の1種またはこれらの混合物よりなるミネラルを混合
すればより効果が優れる。Further, in the present invention, the effect is more excellent if a mineral consisting of one kind of phosphorus, iron, magnesium, copper, zinc, manganese, selenium, rubidium, fluorine and the like or a mixture thereof is mixed.
【0010】スカベンジ作用とは、スーパーオキシドラ
ジカル、ヒドロキシラジカル、アルキルラジカルなどの
活性酸素(フリーラジカル)を補足して消去・除去する
作用である。スカベンジ作用を示す物質としては、ボリ
フェノール類、フラボノイド、アスコルビン酸(ビタミ
ンC)、ビタミンE(トコフェロール)、βカロチン等
が挙げられる。The scavenging action is the action of supplementing active oxygen (free radicals) such as superoxide radicals, hydroxy radicals and alkyl radicals to eliminate and remove them. Examples of substances having a scavenging action include polyphenols, flavonoids, ascorbic acid (vitamin C), vitamin E (tocopherol), β-carotene and the like.
【0011】フェノール化合物としては、グァイアコー
ル、フェノール、オイケノール、フェニルエタノール等
の群より選ばれた1種またはこれらの混合物が挙げられ
る。Examples of the phenol compound include one selected from the group consisting of guaiacol, phenol, eukenol, phenylethanol and the like, or a mixture thereof.
【0012】フラボノイド、糖化フラボノイド等の糖化
合物としては、アスパラチン、オリエンチン(ルテキシ
ン)、シスオリエンチン(ホモオリエンチン、ルトナレ
チン)、イソクエルシチン、ケルセチン、ルチン等の群
より選ばれた1種またはこれらの混合物が挙げられる。The sugar compound such as flavonoid and glycated flavonoid is one selected from the group consisting of aspalathin, orientin (lutexin), cis-orientin (homoorientin, rutonaretin), isoquercitin, quercetin, rutin and the like. A mixture may be mentioned.
【0013】ミネラル成分の抽出とアミノ酸混合物とビ
タミン混合物との混合は、アスパラサス・リネアリスの
葉(茎を含む)にアミノ酸混合物とビタミン混合物を噴
霧、乾燥後抽出して得るのが好ましい。The extraction of the mineral component and the mixing of the amino acid mixture and the vitamin mixture are preferably obtained by spraying the leaves (including the stem) of Aspalathus linealis with the amino acid mixture and the vitamin mixture, drying and extracting.
【0014】抽出法としては、アスパラサス・リネアリ
スの葉または茎にアミノ酸混合物とビタミン混合物を噴
霧乾燥した物を水及び/または有機溶媒で抽出し、該抽
出液より抽出溶媒を留去する方法、またはアスパラサス
・リネアリスの葉または茎にアミノ酸とビタミン混合物
を噴霧乾燥した物を粉砕することによって得ることがで
き、また、通常の日本茶、中国茶、紅茶などの製法と同
様に抽出してもよい。As an extraction method, a method in which leaves or stems of Aspalathus linearis are spray-dried with an amino acid mixture and a vitamin mixture is extracted with water and / or an organic solvent, and the extraction solvent is distilled off from the extract. Alternatively, the leaves or stems of Aspalathus linealis can be obtained by pulverizing a product obtained by spray-drying a mixture of amino acids and vitamins, and can also be extracted in the same manner as ordinary Japanese tea, Chinese tea, black tea, etc. Good.
【0015】水で抽出する場合には、アスパラサス・リ
ネアリスの10〜1000倍の水を加え、90〜100
度で、5〜30分程度抽出するのが好ましい。また、通
常の茶と同様に抽出するときは、アスパラサス・リネア
リスの乾燥葉にアミノ酸とビタミン混合物を噴霧乾燥し
た物の50〜1000倍の水を加え、90〜100度で
5〜30分程度沸騰させ抽出液を得る。In the case of extraction with water, 10 to 1000 times as much water as Aspalathus linealis is added, and 90 to 100
It is preferable to perform extraction for about 5 to 30 minutes. In addition, when extracting in the same way as ordinary tea, add 50 to 1000 times water of spray dried amino acid and vitamin mixture to dried leaves of Aspalathus linearias, and add 5 to 30 minutes at 90 to 100 degrees. Boil to obtain an extract.
【0016】有機溶媒の具体例としては、メタノール、
エタノール、アセトン等が挙げられ、抽出にあたっては
温時抽出等慣用手段を用いることができる。また、抽出
液の分離も、デカンテーションや遠心分離等の慣用手段
を用いることができる。Specific examples of the organic solvent include methanol,
Ethanol, acetone and the like can be mentioned, and conventional means such as warm extraction can be used for extraction. Further, for the separation of the extract, conventional means such as decantation or centrifugation can be used.
【0017】抽出溶媒の留去も凍結乾燥等の慣用手段を
用いることができ、また、アスパラサス・リネアリスの
乾燥葉にアミノ酸とビタミン混合物を噴霧乾燥した物を
粉砕して、粉末化して用いることもできる。A conventional means such as freeze-drying can be used for distilling off the extraction solvent, and the dried leaves of Aspalathus linearias are spray-dried with a mixture of amino acids and vitamins and then pulverized to be used. You can also
【0018】本発明は、生命が誕生した原始の海と同じ
組成比率を持つミネラル混合物とアミノ酸混合物、ビタ
ミン混合物、また必要に応じて添加される抗酸化作用お
よび/またはスカベンジ作用(活性酸素消去・除去作
用)を持つ物質、およびフラボノイドを含有することに
よって初めて優れた効果を示すのであり、ミネラルの組
成比率はナトリウム100%に対して、カリウム80〜
130%、マグネシウム13〜35%、カルシウム8〜
20%、抗酸化作用及び/またはスカベンジ作用(活性
酸素消去・除去能、SOD用活性)の力価が10,00
0〜100,000単位/g、糖化合物0.2〜20m
g/g、及びフェノール化合物を1〜20%、また微量
ミネラルを添加するときは、0.01μg/g〜5mg
/gを含有することが必要である。The present invention relates to a mineral mixture and amino acid mixture having the same compositional ratio as that of the primitive sea where life was born, a vitamin mixture, and an antioxidant action and / or scavenging action (active oxygen elimination / It has an excellent effect only when it contains a substance having a scavenging action) and flavonoids, and the composition ratio of minerals is 100% sodium to 80% potassium.
130%, magnesium 13-35%, calcium 8-
20%, antioxidant and / or scavenging activity (active oxygen scavenging / scavenging ability, activity for SOD) of 10,000
0 to 100,000 units / g, sugar compound 0.2 to 20 m
g / g, and 1 to 20% of phenol compounds, and when adding trace minerals, 0.01 μg / g to 5 mg
It is necessary to contain / g.
【0019】本発明の構成物質はいずれも無毒性のもの
で薬理基準にも合致したもので、ラットに対する急性毒
性試験で死亡例は皆無であり、生化学血液検査および病
理組織学的検査においても異常が認められなかった。All of the constituents of the present invention are non-toxic and meet the pharmacological criteria. There are no deaths in the acute toxicity test on rats, and no biochemical blood tests or histopathological tests are conducted. No abnormality was found.
【0020】本組成物は、有効成分を生理学的に許容さ
れうる担体、賦形剤、結合剤、希釈剤と混合してそのま
ま溶液、粉末顆粒、錠剤、乳剤、ゼリー状など任意の形
態で単独投与、濃縮液を利用、またはその他の健康食
品、栄養剤、健康補助剤に混合し用いることもできる。The present composition is prepared by mixing the active ingredient with physiologically acceptable carriers, excipients, binders and diluents, and as such is used in any form such as solution, powder granules, tablets, emulsions and jellies. It can be used by administration, a concentrated solution, or mixed with other health foods, nutritional supplements and health supplements.
【0021】投与量は、対象となる人の年齢、性別、対
象となる疾患の種類、程度により異なるが、健康補助剤
・栄養剤として常用する場合には、組成物2〜400m
g/kg/日の範囲で用いるのが好ましく、飲料として
常用する場合には、0.2〜10%溶液を100ml〜
500ml/日飲食するのが好ましい。The dose varies depending on the age and sex of the target person, the type and degree of the target disease, but when used as a health supplement / nutrition agent, the composition is 2 to 400 m.
It is preferably used in the range of g / kg / day, and when used as a beverage, 100 ml of a 0.2-10% solution is used.
It is preferable to eat and drink 500 ml / day.
【0022】[0022]
【作用】成人病および/あるいは老年病の発病要因は複
雑で不明な点が多いが、多くの疾患はミネラルバランス
の異常と体内の活性酸素が深く関わっている可能性があ
る。生命が誕生した原始の海のミネラル組成比率をアス
パラサス・リネアリス抽出物から得、これとアミノ酸混
合物とビタミン混合物、及び、スーパーオキシドラジカ
ルなどの活性酸素の除去するスカベンジ作用(SOD様
活性)を有する物質および糖化合物などの物質が組合わ
さって、身体の体液組成を容易に維持・平衡化して細胞
を活性化して成人病、老人病を改善し健康を維持するも
のと考えられる。[Function] Although the etiological factors of adult diseases and / or geriatric diseases are complicated and unclear, many diseases may be deeply related to abnormal mineral balance and active oxygen in the body. The ratio of mineral composition of the primitive sea where life was born is obtained from Aspalathus linealis extract, and it has a scavenging action (SOD-like activity) for removing active oxygen such as amino acid mixture and vitamin mixture, and superoxide radical. It is considered that a substance and a substance such as a sugar compound are combined to easily maintain and balance the body fluid composition of the body to activate cells to improve adult diseases and geriatric diseases and maintain health.
【0023】このように原始の海の体液組成比率は、身
体の体液組成比率と同じであり、そのような組成比率の
ミネラルを採取した場合、体内のミネラルバランスを維
持することが容易であり、細胞を活性化することができ
る。Thus, the body fluid composition ratio of the primitive sea is the same as the body fluid composition ratio of the body, and when minerals having such a composition ratio are collected, it is easy to maintain the mineral balance in the body, The cells can be activated.
【0024】[0024]
【効果】本発明は、ヒトを含む哺乳動物の成人病および
/または老年病の疾患を副作用無く、飲食等による内服
として迅速に改善することができ、ヒトの健康を増進
し、糖尿病、皮膚疾患、便秘、アトピー性皮膚炎、肝臓
疾患、リウマチ、高血圧、パーキンソン病、水虫、2日
酔防止、鬱病・精神不安、ストレス、腎臓病、白内障、
肌荒れ、腫瘍、などの疾患を飲食等により副作用無く、
迅速に改善治療することができる。[Effects] The present invention can rapidly improve adult diseases and / or geriatric diseases of mammals including humans without adverse effects as oral administration by eating and drinking, etc., and promote human health, diabetes, and skin diseases. , Constipation, atopic dermatitis, liver disease, rheumatism, hypertension, Parkinson's disease, athlete's foot, hangover prevention, depression / mental anxiety, stress, kidney disease, cataract,
No side effects such as rough skin, tumor, etc. due to eating and drinking,
Improving treatment can be done quickly.
【0025】[0025]
【実施例】採取したアスパラサス・リネアリスの葉(茎
つき)を5mm長に切断後、ローリング、酸素 酵、天
日乾燥の工程を経て乾燥葉とする。乾燥葉3.5gにア
ミノ酸混合物とビタミン混合物を噴霧した後、乾燥した
葉を水1.5リットルで15分間沸騰させ抽出液を得
た。[Examples] The collected leaves of Aspalathus linealis (with stem) are cut into 5 mm lengths, and then subjected to steps of rolling, oxygen fermentation, and sun drying to obtain dried leaves. After spraying 3.5 g of dried leaves with the amino acid mixture and the vitamin mixture, the dried leaves were boiled with 1.5 liters of water for 15 minutes to obtain an extract.
【0026】得られた抽出液から、鉄(0.86mg/
100g)、リン(22.9mg/100g)、カルシ
ウム(22.2mg/100g)、ナトリウム(211
mg/100g)、カリウム(232mg/100
g)、マグネシウム(67.1mg/100g)、銅
(0.57ppm)、亜鉛(1.62ppm)、マンガ
ン(18.5ppm)、リチウム(0.15ppm)、
ルビジウム(6.0ppm)、アミノ酸混合物(0.5
〜10%)、ビタミン混合物(400〜700mg/1
00g)のミネラルの組成比率を得、糖化合物として糖
化フラボノイド1〜50mg/g、フェノール3〜15
%を溶液状のまま混合し、スカベンジ作用(SOD様活
性)および/または抗酸化能として力価20,000単
位/g以上となるように調製した。得られた組成物に水
を添加し、組成物が1%を含有する溶液を得た。From the obtained extract, iron (0.86 mg /
100 g), phosphorus (22.9 mg / 100 g), calcium (22.2 mg / 100 g), sodium (211)
mg / 100 g), potassium (232 mg / 100)
g), magnesium (67.1 mg / 100 g), copper (0.57 ppm), zinc (1.62 ppm), manganese (18.5 ppm), lithium (0.15 ppm),
Rubidium (6.0 ppm), amino acid mixture (0.5
-10%), vitamin mixture (400-700mg / 1
00g) of mineral composition ratio, saccharified flavonoid as sugar compound 1 to 50 mg / g, phenol 3 to 15
% Was mixed in the form of a solution and prepared so as to have a scavenging effect (SOD-like activity) and / or an antioxidative ability of a titer of 20,000 units / g or more. Water was added to the obtained composition to obtain a solution containing 1% of the composition.
【0027】また、アミノ酸混合物の化学分析結果は下
記の通りである。フェニルアラニン(0.30g/10
0g)、リジン(0.54g/100g)、スレオニン
(0.51g/100g)、トリブトファン(0.08
g/100g)、バリン(0.37g/100g)、イ
ソロイシン(0.30g/100g)、ロイシン(0.
45g/100g)、メチオニン(0.17g/100
g)、タウリン(5.11%)、グルタミン酸(2.7
8g/100g)、アスパラギン酸(1.20g/10
0g)。The results of chemical analysis of the amino acid mixture are as follows. Phenylalanine (0.30g / 10
0 g), lysine (0.54 g / 100 g), threonine (0.51 g / 100 g), tributofane (0.08)
g / 100 g), valine (0.37 g / 100 g), isoleucine (0.30 g / 100 g), leucine (0.
45 g / 100 g), methionine (0.17 g / 100)
g), taurine (5.11%), glutamic acid (2.7)
8g / 100g), aspartic acid (1.20g / 10
0 g).
【0028】さらに、ビタミン混合物の化学分析結果は
下記の通りである。ビタミンB1(59.1mg/10
0g)、B2(62.4mg/100g)、B6(0.
17mg/100g)、B12(52μg)、コリン
(430mg/100g)、イノシトール(117mg
/100g)、ビオチン(7.7μg)、葉酸(0.1
3mg/100g)を含有する。Further, the results of chemical analysis of the vitamin mixture are as follows. Vitamin B1 (59.1 mg / 10
0 g), B2 (62.4 mg / 100 g), B6 (0.
17 mg / 100 g), B12 (52 μg), choline (430 mg / 100 g), inositol (117 mg)
/ 100 g), biotin (7.7 μg), folic acid (0.1
3 mg / 100 g).
【0029】香気成分としては、カルボニル化合物(1
5%)、カロチノイド分解物(17%)、炭素数2〜1
2の有機酸(22%)、フェノール化合物(13%)、
芳香族含酸素化合物(7%)、芳香族炭化水素(7
%)、テルベノイド(4%)などを含有する。As the aroma component, a carbonyl compound (1
5%), carotenoid decomposition product (17%), carbon number 2-1
2 organic acids (22%), phenolic compounds (13%),
Aromatic oxygen-containing compound (7%), aromatic hydrocarbon (7
%), Terbenoid (4%) and the like.
【0030】実施例1 製造例で得た抽出液を表1に示す各種疾患のパネラー
に、一日500ml〜1000mlを2週間飲用した
後、症状の改善を調べた。その結果、高い率で症状の改
善が認められ、飲食前に比して、健康状態がよくなり、
糖尿病、肝臓病などの各種疾患の症状が改善され日常生
活に支障もなくなった。Example 1 The extract obtained in the production example was drunk at 500 ml to 1000 ml per day for 2 weeks on the panelists of various diseases shown in Table 1, and the improvement of symptoms was examined. As a result, a high rate of improvement in symptoms was observed, and the health condition was better than before eating and drinking.
Symptoms of various diseases such as diabetes and liver disease have been improved and there has been no hindrance to daily life.
【0031】[0031]
【表1】 [Table 1]
───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.6 識別記号 庁内整理番号 FI 技術表示箇所 A61K 33/00 45/00 ─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. 6 Identification code Internal reference number FI technical display area A61K 33/00 45/00
Claims (3)
つミネラル混合物、アミノ酸、ビタミン、スカベンジ作
用および/または抗酸化能を有する物質、フェノール化
合物、フラボノイド及び糖化フラボノイド等の糖化合物
を含有してなる栄養補助剤。1. A mineral mixture having a mineral composition ratio similar to that of the primitive sea, an amino acid, a vitamin, a substance having a scavenging action and / or an antioxidant ability, a sugar compound such as a phenol compound, a flavonoid and a glycated flavonoid. Nutritional supplements.
0%に対して、カリウム80〜130%、マグネシウム
13〜35%、カルシウム8〜20%であることを特徴
とする請求項1記載の栄養補助剤。2. The composition ratio of minerals is sodium 10
The nutritional supplement according to claim 1, wherein potassium is 80 to 130%, magnesium is 13 to 35%, and calcium is 8 to 20% with respect to 0%.
リスの抽出物から得ることを特徴とする請求項1または
2記載の栄養補助剤。3. Nutritional supplement according to claim 1 or 2, characterized in that the mineral mixture is obtained from an extract of Aspalathus linealis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6194620A JPH0840923A (en) | 1994-07-28 | 1994-07-28 | Nutrient-supplying agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6194620A JPH0840923A (en) | 1994-07-28 | 1994-07-28 | Nutrient-supplying agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH0840923A true JPH0840923A (en) | 1996-02-13 |
Family
ID=16327564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6194620A Pending JPH0840923A (en) | 1994-07-28 | 1994-07-28 | Nutrient-supplying agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0840923A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0956867A1 (en) * | 1998-05-12 | 1999-11-17 | Franz-Peter Dr. Liebel | Use of flavonoid glycosides, tanning agents and microorganisms for the therapy and prophylaxis of diabetes mellitus |
| JP2002051732A (en) * | 2000-06-12 | 2002-02-19 | Access Business Group Llc | Composition and method for correcting deficiency disease of vegetable chemical substance by diet |
| JP2005522486A (en) * | 2002-04-08 | 2005-07-28 | ザ デイリー ウェルネス カンパニー | Methods and compositions for improving fertility health in animal males and females, and humans |
| JP2007020432A (en) * | 2005-07-13 | 2007-02-01 | Asahi Breweries Ltd | Alcohol metabolism promoting beverage |
| JP2008533131A (en) * | 2005-03-18 | 2008-08-21 | ユニジェン インク. | Histamine-suppressing composition containing isoorientin |
| JP2009256364A (en) * | 2009-06-24 | 2009-11-05 | Daily Wellness Co | Method and composition for improving health state of fertilizing capacity of male and female animal and human |
| JP2011067197A (en) * | 2003-08-26 | 2011-04-07 | Mannatech Inc | Antioxidant sensor, method, and composition |
| WO2013047613A1 (en) * | 2011-09-27 | 2013-04-04 | 花王株式会社 | Containerized beverage |
-
1994
- 1994-07-28 JP JP6194620A patent/JPH0840923A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0956867A1 (en) * | 1998-05-12 | 1999-11-17 | Franz-Peter Dr. Liebel | Use of flavonoid glycosides, tanning agents and microorganisms for the therapy and prophylaxis of diabetes mellitus |
| JP2002051732A (en) * | 2000-06-12 | 2002-02-19 | Access Business Group Llc | Composition and method for correcting deficiency disease of vegetable chemical substance by diet |
| JP2005522486A (en) * | 2002-04-08 | 2005-07-28 | ザ デイリー ウェルネス カンパニー | Methods and compositions for improving fertility health in animal males and females, and humans |
| JP2011067197A (en) * | 2003-08-26 | 2011-04-07 | Mannatech Inc | Antioxidant sensor, method, and composition |
| JP2008533131A (en) * | 2005-03-18 | 2008-08-21 | ユニジェン インク. | Histamine-suppressing composition containing isoorientin |
| JP2007020432A (en) * | 2005-07-13 | 2007-02-01 | Asahi Breweries Ltd | Alcohol metabolism promoting beverage |
| JP2009256364A (en) * | 2009-06-24 | 2009-11-05 | Daily Wellness Co | Method and composition for improving health state of fertilizing capacity of male and female animal and human |
| WO2013047613A1 (en) * | 2011-09-27 | 2013-04-04 | 花王株式会社 | Containerized beverage |
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