JPH0778235B2 - Cleaning composition - Google Patents

Description

TECHNICAL FIELD OF THE INVENTION The present invention relates to a cleansing composition which suppresses skin irritation by blending a mixture of α-, β- and γ-cyclodextrins.

Conventional technology and its problems Conventional cleaning compositions for households such as kitchen detergents,
It is known that β-cyclodextrin is blended to suppress skin irritation (see Japanese Patent No. 1402779 and Japanese Patent Laid-Open No. 267218/1987). However, β-cyclodextrin has a low solubility in a detergent and its stimulative effect was not sufficient. It has also been proposed to use a methylated cyclodextrin as a cleaning agent (Japanese Patent Laid-Open No. S60-12065).
No. 62-62897) is very expensive because it is chemically modified.

The present inventors have made various studies on such problems, and surprisingly, a mixture of α, β and γ-cyclodextrin (mixed cyclodextrin) is unexpectedly used as a detergent at a higher concentration than in the case of β-cyclodextrin alone. The present invention has been completed based on the finding that it can be dissolved.

Means for Solving the Problems The present invention is characterized by blending 50 to 80% by weight of α-cyclodextrin, 15 to 45% by weight of β-cyclodextrin and 5 to 20% by weight of γ-cyclodextrin mixed cyclodextrin. A cleaning composition is provided.

The mixed cyclodextrin used in the present invention is 6 to
A cyclodextrin-forming enzyme (Cycloamylos), which is a non-reducing maltooligosaccharide in which eight glucose (glucose) molecules are linked cyclically by α-1,4-glucoside bonds and is produced by microorganisms of the genus Bacillus sp. Glucan
It is obtained by acting otransferase) on starch. As the mixed cyclodextrin, α-cyclodextrin 50 to 80% by weight, β-cyclodextrin 15 to
Those containing 45% by weight and 5-20% by weight of γ-cyclodextrin are used. Such a mixed cyclodextrin has a significantly higher solubility in a detergent than conventionally used β-cyclodextrin, and irritation of the detergent to the skin is significantly suppressed. If the blending ratio of each of α-, β-, and γ-cyclodextrins in the mixed cyclodextrin is out of the above range, the solubility in a detergent is low and the effect of suppressing skin irritation decreases.

The results of examining the solubility of the cyclodextrin used in the present invention in water are shown in FIG. As is clear from FIG. 1, α-cyclodextrin (α-CD) and β-cyclodextrin (β
-CD) and γ-cyclodextrin (γ-CD), the solubility of mixed cyclodextrins (mixed CD; α: 60%, β: 30%, γ: 10%) is much higher than that of each cyclodextrin alone. Very expensive.

β-Cyclodextrin has low water solubility, and a benzene ring is stably included, but is unstable when a fatty acid is included. However, by combining α, β, γ-cyclodextrin, the solubility is synergistically improved as compared with the case of alone, and as a result, it becomes possible to include a wider range of stimulants, It is estimated that the irritation suppression effect was significantly improved.

The cleaning composition of the present invention is used as a kitchen detergent, a detergent for clothes, a cleaning agent for a household, and the like, and a surfactant and other components are added depending on the type of the cleaning composition.

For example, anionic surfactants such as sulfate ester salts, alkyl allyl sulfonates, acylmethyl sulfonates, α-olefin sulfonates, alkane sulfonates, acyl amino acid salts, alkyl sulfosuccinates and alkyl ether carboxylates. Sucrose fatty acid ester, alkanolamide, polyoxyethylene alkylamine, polyoxyethylene fatty acid amide, alkyl ether activator, alkyl allyl ether activator, polyoxyethylene fatty acid ester, phenyl ether activator, polyoxyalkylene polymer Nonionic surfactants such as combined and tetronic type surfactants; cationic surfactants such as mono long-chain alkyl trimethyl ammonium salts and di long chain alkyl dimethyl ammonium salts; imidazoline-based surfactants, mono alkyl dimes Le betaine, amphoteric surfactants such as monoalkyl amidopropyl dimethyl betaine; amine oxide type surfactants, palmitic acid, myristic acid, oleic acid, stearic acid, behenic acid,
Higher fatty acids such as coconut oil fatty acid and tallow fatty acid; silicon derivatives; protein hydrolysates, cationized water-soluble polymers, nonionic water-soluble polymers such as polyvinylpyrrolidone and its derivatives and cellulose derivatives, methyl vinyl ether maleic acid butyl ester Polymers, anionic water-soluble polymers such as xanthan gum, and amphoteric water-soluble polymers such as acrylic acid methacrylic acid ester copolymers; UV absorbers such as oxybenzone and cinnamic acid ester derivatives; tripolyphosphate , Metaphosphate, pyrophosphate, orthophosphate, silicate, zeolite, carbonate,
Builders such as sulfates and perborates; polyhydric alcohols such as propylene glycol, 1,3-butylene glycol, sorbitol, polypropylene glycol, glycerin; alcohols such as ethanol, isopropanol, methanol; CFCs, LPG, DME, etc. Propellant; other known pH regulators, moisturizers, fragrances, chelating agents, pigments, animal and plant extracts, refreshing agents, germicides, preservatives, antioxidants, antistatic agents, brighteners, enzymes, etc. Any of the above components can be appropriately mixed.

The detergent composition of the present invention can be made into a usual form such as a kitchen detergent, a laundry detergent, and a household detergent by a conventional method.

EXAMPLES Next, the present invention will be described more specifically based on Examples and Comparative Examples. The cleaning compositions obtained in Examples and Comparative Examples were evaluated by the following methods.

(Transparency) After being left in a thermostatic chamber at -5 ° C for 1 week, the appearance was visually checked and observed for precipitation and cloudiness.

(Skin irritation) A 5% aqueous solution of the test detergent was subjected to a closed patch test for 24 hours on the upper arms of 30 healthy persons. The state of the skin one hour after the removal of the test solution was judged with a magnifying glass, and the one showing a clear reaction was regarded as positive. Out of 30 people, 5 or more were positive and poor, and those with less than 5 were good.

Example 1 (Kitchen Detergent) A kitchen detergent was prepared by the following method according to a conventional method. Ingredient weight% Polyoxyethylene lauryl ether sodium sulfate 1
5.0 Coconut oil fatty acid diethanolamide 5.0 Mixed cyclodextrin (α: 60%, β: 30%, γ: 10
%) 0.4 Perfume 0.2 Water balance Example 2 (kitchen detergent) Ingredients Weight% Polyoxyethylene alkyl (C ₁₂ -C ₁₃₎ ether sulfate (EO3 mol) 10.0 secondary sodium alkane sulfonate 5.0 coconut oil fatty acid diethanolamide 5.0 Mixed cyclodextrin (α: 60%, β: 30%, γ: 10
%) 0.5 Perfume 0.2 Water balance Example 3 (kitchen detergent) Ingredient weight% Sodium α-olefinsulfonate 10.0 Lauryl dimethylamine oxide 5.0 Coconut oil fatty acid diethanolamide 5.0 Mixed cyclodextrin (α: 80%, β: 15%, γ :Five%)
0.2 Fragrance 0.2 Water balance Example 4 (kitchen detergent) Component wt% Coconut oil fatty acid amide propyldimethylamino acetic acid betaine 5.0 Polyoxyethylene lauryl ether sodium sulfate (EO3 mol) 10.0 Lauric acid-myristic acid monoethanolamide 5.0 Mixed cyclodextrin ( α: 50%, β: 30%, γ: 20
%) 0.1 Fragrance 0.2 Water Remainder Example 5 (detergent for clothing) A detergent for clothing was prepared according to a conventional method according to the following formulation. Ingredient wt% Sodium coconut oil fatty acid 13.0 Polyoxyethylene (EO7 mol) Alkyl (C ₁₃ ~
C ₁₅ ) ether 22.0 monoisopropanolamine 3.0 methyl alcohol 10.0 coconut oil fatty acid diethanolamide 2.0 hydroxyethanediphosphonic acid 0.2 mixed cyclodextrin (α: 60%, β: 30%, γ: 10
%) 0.2 Perfume 0.1 Water balance Example 6 (laundry detergents) Component Weight% Polyoxyethylene (E06 moles) alkyl (C ₁₀ -
C ₁₄ ) ether 17.0 LAS diethanolamine salt 60.0 coconut oil fatty acid diethanolamide 21.0 alkaline phosphatase 0.3 lipase 0.2 hard water (100 ppm) balance mixed cyclodextrins (α: 60%, β: 30%, γ: 10
%) 0.5 Fragrance 0.2 Example 7 (Carpet shampoo) A carpet shampoo was prepared according to a conventional method according to the following formulation. When using, dilute 40 times. Ingredient wt% Sodium lauryl sulfate 6.0 Magnesium lauryl sulfate 6.0 Lauroyl sarcosine sodium 10.0 Mixed cyclodextrin (α: 60%, β: 30%, γ: 10
%) 0.1 Antistatic agent Trace amount Perfume 0.05 Water Remainder The detergents of the present invention of Examples 1 to 7 did not cause precipitation or clouding even when left at -5 ° C for 1 week, and the skin irritation was evaluated well. .

Comparative Examples 1 to 3 In Example 2, mixed cyclodextrins were each α-,
A kitchen detergent was prepared with the same composition except that β- and γ-cyclodextrin was changed to 100%. When evaluated by the above-mentioned evaluation methods, in all cases, clouding and precipitation occurred when left at -5 ° C, and the evaluation of skin irritation was also poor.

[Effect of the Invention] The cleaning composition of the present invention causes less irritation to the skin,
And it has excellent foaming power.

[Brief description of drawings]

FIG. 1 is a graph showing the solubility of cyclodextrin.

Claims (1)

[Claims] 1. α-Cyclodextrin 50 to 80% by weight, β
A detergent composition comprising 15 to 45% by weight of cyclodextrin and 5 to 20% by weight of γ-cyclodextrin mixed cyclodextrin.