JPH07173001A - Agrochemical solid formulation - Google Patents

Abstract

(57) [Summary] [Structure] A solid agricultural chemical formulation containing acephate and condensed sodium phosphate, a method for stabilizing a solid agricultural chemical formulation containing condensed sodium phosphate added to a solid pharmaceutical formulation containing acephate, and condensed sodium phosphate Stabilized acephate added. [Effect] The addition of condensed sodium phosphate improves the storage stability of acephate in the acephate drug substance or the agricultural chemical solid preparation containing acephate.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a stabilized agricultural chemical solid preparation containing acephate and stabilization of acephate.

2. Description of the Related Art Acephate (O, S-dimethyl acetylphosphoramidothioate) is used in The Pesticide Ma
nual 8th edition (1987 The British Crop Protection Cou
(published by Ncil) The compound having insecticidal activity described on page 1 and the like, and is currently used as an active ingredient of agricultural insecticides because it is effective in controlling various pests.

However, since acephate is not very stable in pesticide formulations,
Depending on storage conditions, the acephate in the preparation was decomposed severely, and as a result, the insecticidal efficacy of acephate could not be effectively utilized. Therefore, it has been desired to develop a stable agricultural chemical composition containing acephate.

[0002]

The present invention provides a stabilized agricultural chemical solid preparation containing acephate and condensed sodium phosphate, and the addition of condensed sodium phosphate allows the acephate drug substance or the agricultural chemical solid to be solidified. This is because the acephate in the preparation is stabilized. The condensed sodium phosphate referred to in the present invention refers to sodium phosphate in which two or more are condensed across an oxygen atom, and examples thereof include sodium polyphosphate, sodium tripolyphosphate, and sodium pyrophosphate. The amount of condensed sodium phosphate effective for stabilizing acephate is generally 0.01 to 1 per 1 part by weight of acephate.
It is 0 part by weight, preferably 0.05 to 1 part by weight.

The content of acephate in the solid agricultural chemical preparation of the present invention is generally 0.5 to 99% by weight, preferably 5 to 9%.
The content of the condensed sodium phosphate as a stabilizer is 5% by weight, and the content of the stabilized sodium phosphate can stabilize the acephate, and is usually 0.
It is from 01 to 50% by weight, preferably from 1 to 20% by weight, more preferably from 1 to 10% by weight. The agricultural chemical solid preparation of the present invention usually contains a solid carrier for agricultural chemical preparations other than acephate and condensed sodium phosphate, and examples of the solid carrier for pharmaceutical preparation include kaolin clay, attapulgite clay,
Mineral carriers such as sericite clay, pyrophyllite clay, montmorillonite clay, zeolite, bentonite, acid clay, activated clay, serpentine, talc, diatomaceous earth, inorganic salts such as sulfates, nitrates and chlorides, and synthesis of silica Examples thereof include inorganic carriers such as carriers, and organic carriers such as sugars, starch, dextrin, wheat flour, soybean flour, corn flour, and wood flour. These solid carriers for formulation are usually contained in the agricultural chemical solid formulation of the present invention in an amount of 1 to 90% by weight, preferably 20 to 70% by weight.

The agricultural chemical solid preparation of the present invention may further contain various kinds of auxiliary agents for agricultural chemical preparations, such as surfactants, dyes, fragrances, known stabilizers and the like. And these are contained in the agrochemical composition of the present invention,
The content is usually 0.5 to 30% by weight, preferably 2 to 10% by weight. Examples of the surfactant include alkyl sulfate salts such as sodium lauryl sulfate, alkyl aryl sulfonates such as sodium alkyl naphthalene sulfonate, lignin sulfonates such as sodium lignin sulfonate, succinate derivative, and polycarboxylic acid salt. Anionic surfactants such as polyethylene glycol alkyl aryl ether sulfate ester salt, formaldehyde condensate of aromatic sulfonate, nonionic properties such as polyoxyethylene alkyl ether, polyoxyethylene alkyl aryl ether, polyoxyethylene aryl aryl ether, etc. Surfactants may be mentioned.
The agricultural chemical solid preparation of the present invention may further contain other agricultural chemical active ingredients, for example, pyrethroid compounds such as fenpropatorin, fenvalerate and esfenvalerate.

The pesticide solid preparation of the present invention comprises acephate,
Condensed sodium phosphate, a solid carrier for agricultural chemicals, and if necessary, a surfactant and the like are added, mixed with a mixer, etc., and finely pulverized with an pulverizer such as an air mill, a hammer mill, a centrifugal pulverizer to an average particle size of 20 μm or less The powdered agrochemical solid formulation of the present invention, or by further crushing these pulverized products into granules using a compression molding machine such as a roller compactor, an extrusion granulator, or a tumbling granulator,
It is produced by an ordinary method such as a granular pesticide solid preparation of the present invention.

[0006]

The present invention will be described in more detail below with reference to formulation examples and test examples, but the present invention is not limited to the following examples. Formulation Example 1 25 parts by weight of acephate, sodium tripolyphosphate 5
4 parts by weight of sodium dodecylbenzene sulfonate, 2 parts by weight of a condensate of sodium aromatic sulfonate and formaldehyde, 20 parts by weight of Tokusil GU-N (synthetic silica made by Tokuyama Soda) and 44 parts by weight of kaolin clay are jet milled. Was pulverized and mixed with a mixer to obtain a wettable powder which is the solid agricultural chemical preparation of the present invention. Formulation Example 2 In the same manner as in Formulation Example 1, except that 10 parts by weight of sodium tripolyphosphate was used in place of 5 parts by weight and 39 parts by weight of kaolin clay was used in place of Formulation Example 1,
A wettable powder, which is the agricultural chemical solid preparation of the present invention, was obtained.

Test Example The wettable powders obtained in the above Formulation Examples 1 and 2 were enclosed in an aluminum laminate bag and stored in a thermostat at 50 ° C. for 2 weeks. The content of acephate in the preparation before and after storage was measured using gas chromatography, and the decomposition rate was determined by the following formula.

[Equation 1] Further, in Preparation Example 1, sodium tripolyphosphate 5
The degradation rate was similarly determined for a comparative formulation prepared in the same manner by using 5 parts by weight of kaolin clay instead of parts by weight. The results are shown in Table 1.

[Table 1]

[0008]

Effect of the Invention The addition of condensed sodium phosphate improves the storage stability of acephate in the solid drug formulation containing acephate drug substance or acephate.

Claims (5)

[Claims] 1. A pesticide solid preparation comprising acephate and condensed sodium phosphate. 2. A solid pesticide formulation, comprising 5 to 95% by weight of acephate, 1 to 20% by weight of condensed sodium phosphate, and a solid carrier for pesticide formulation. 3. A pesticide solid preparation containing acephate,
A method for stabilizing an agricultural chemical solid preparation, which comprises adding condensed sodium phosphate. 4. The stabilizing method according to claim 3, wherein the addition amount of condensed sodium phosphate is 0.05 to 1 part by weight with respect to 1 part by weight of acephate. 5. A stabilized acephate to which condensed sodium phosphate is added.