JPH0714894Y2 - Capillary for sample suction - Google Patents

Description

[Detailed Description of the Invention] [Industrial field of application] The present invention relates to a sample suction thin tube used in a sample analyzer such as a blood analyzer, and more specifically, a container for sticking a rubber stopper of a sealed sample container. The present invention relates to a thin tube capable of sucking an internal sample.

[Conventional technology]

To aspirate a sample from a sealed container such as a vacuum blood collection tube,
A thin tube with a sharp tip is used. The following is a conventional example.

(A) An injection needle having a blade at the tip and an opening at the tip.

(B) The double-tube structure needle described in JP-A-58-76765. The tip of this needle is conical and two openings are provided as lateral holes near the tip.

[Problems to be solved by the invention]

The thin tube used for sample suction of the sample analyzer,
At a minimum, the following are required:

(A) High durability.

(B) When the plug is pierced, fragments of the plug, such as rubber dust, are unlikely to occur, and the fragments do not clog the thin tube.

The conventional technology has the following problems. In (a), not only durability is not taken into consideration, but also the opening is at the tip, so that the hole is likely to be clogged by the fragment of the plug.

In (b), the pipe diameter is large due to the double structure. Therefore, when the plug is pierced, it receives a large frictional force and is easily worn. Further, since the tip has a conical shape, the plug is pierced while being pryed open, so that a fragment of the plug is likely to occur. Further, since the thin tube has a single structure, the center of the plug is pierced many times when re-measurement is performed later, so that the plug becomes brittle and fragments of the plug are likely to occur.

The present invention has been made in view of the above points, and an object of the present invention is to provide a sample suction thin tube that is excellent in durability (wear resistance) and that is unlikely to be clogged by a fragment of a plug.

[Means for solving problems]

In order to achieve the above object, the sample suction thin tube of the present invention is, as shown in the drawings, a sample thin tube 10 for sucking a sample, a ventilation thin tube 12 for aeration, and these two tubes. And a holder 14 for holding the thin tubes 10 and 12, and two blades 16 and 18 are provided at the tips of the two thin tubes 10 and 12, respectively.
Horizontal hole-shaped openings 20 in the cylindrical parts near the tips of 10 and 12,
22 is bored, the sealing member 24 and the adhesive 26 are sealed from the tip to the opening, and a coating 29 having excellent wear resistance is formed on the tip portion including the two thin blades 16 and 18 and the openings 20 and 22. Further, the opening 22 of the ventilation thin tube 12 is located in front of the opening 20 of the sample thin tube 10.

[Action]

When the tips of the thin tubes 10 and 12 come into contact with the stopper 52 of the sealed container and further advance, the thin tubes 10 and 12 pierce the stopper 52 while cutting the stopper 52 by the blades 16 and 18 provided at the ends. Since the stopper is cut open rather than widened, the frictional force generated between the thin tube and the stopper is small.

Further, since the hardness is increased by forming the coating having excellent wear resistance, it is possible to use a thin thin tube and further reduce the frictional force. The smaller the frictional force, the less likely it is to wear and the less likely the fragments of the plug will be generated.

Since the openings 20 and 22 of the thin tubes 10 and 12 are not opened in the traveling direction of the thin tubes and are provided laterally on the cylindrical portion of the thin tubes, the fragments of the plug do not clog the openings 20 and 22. Further, since the opening 22 of the ventilation thin tube 12 is provided in front of the opening 20 of the sample thin tube 10, first, the inside of the sample container communicates with the atmosphere by entering the opening 22 into the sample container. After being brought to the atmospheric pressure, the opening 20 enters the inside of the sample container to suck the sample.

In addition, since two thin tubes are provided and pierce the positions a little apart from each other from the center of the stopper, the piercing position changes every time the sample container is installed.

〔Example〕

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the drawings. However, unless otherwise specified, the materials, shapes, relative positions, etc. of the constituent devices described in this embodiment are not intended to limit the scope of the present invention to them only, and are merely descriptions. It's just an example.

FIG. 1 is a right side view of a partial cross section of an embodiment of the sample suction thin tube of the present invention, FIG. 2 is a bottom view of the same, and FIG. 3 is a front view of the same.

The sample suction thin tube of the present invention comprises thin tubes 10 and 12 and a holder 14 for holding these two thin tubes. Thin tube 10,
12 is a stainless steel thin tube with an outer diameter of 1.3 to 0.6 mm and a wall thickness of 0.15 to 0.2 mm.
It is joined to 14. The thin tube 10 is a thin tube for a sample, and is a thin tube for leading the sample in the sample container to the outside of the container. Thin tube 12
Is a thin tube for ventilation, and is a thin tube for introducing air from the outside of the sample container to the inside of the container in order to bring the inside of the sample container to atmospheric pressure.

Since the blade 16 is provided at the tip of the thin tube 10, the thin tube can be pierced at last while cutting the plug instead of piercing it while spreading the plug made of rubber or the like. In other words, since the frictional force generated between the plug and the thin tube 10 is small, rubber residue or the like is less likely to occur and the thin tube 10 is less likely to wear. Further, since the driving force for moving the thin tube may be small, the force applied to the sample container is small, and there is no fear of damage to the container.

The thin tube 10 is provided with a lateral hole with a chamfered edge on the cylindrical portion of the thin tube, which is several mm away from the tip of the thin tube, and forms an opening 20 through an inner passage 28. FIG. 4 is an enlarged view of part A in FIG. 2, and FIG. 5 is BB in FIG.
It is a line sectional view. A cylindrical encapsulating member 24 that is tightly fitted in the passage 28 is inserted from the opening at the tip of the thin tube 10 to a position where it comes into contact with the opening 20, and further sealed with, for example, a thermosetting adhesive 26. Therefore, the sample sucked through the opening 20 flows through the passage 28 without pooling, and is drawn out of the sample container.
Since the opening 20 is a lateral hole, pieces of plug such as rubber residue will not be blocked.

Further, the tip end portion of the thin tube including the blade 16 and the opening 20 is subjected to a coating treatment excellent in wear resistance and corrosion resistance to form a coating film 29. Note that C is a tip end portion that has been subjected to a coating treatment. Although various coating methods can be considered, it is preferable to form a titanium carbide film and a titanium nitride film thereon by an ion plating method. By increasing the wear resistance in this way, the hardness was also increased, and the thin tube 10 could be made thin with an outer diameter of about 0.8 mm and an inner diameter of about 0.5 mm.

Therefore, the frictional force is further reduced, and the fragments of the plug are less likely to be generated. The tip end of the thin tube has increased hardness and is less likely to rub, but the other part is not coated, and therefore remains elastic to some extent against bending of the thin tube. For this reason, when the thin tube advances and pierces the stopper, even if the stopper slightly shifts in the left-right direction, the thin tube can return to its original state without being bent when pulled out from the stopper. That is, it is possible to prevent plastic deformation of the thin tube. Therefore, it is possible to prevent breakage of the thin tube.

The thin tube 12 is a blade 18, an encapsulating member, an adhesive, in the same manner as the thin tube 10.
An opening 22 is provided and a coating process is performed.

As shown in FIG. 2, the thin tubes 10 and 12 have a lateral hole-shaped opening 22 of the thin tube 12 in front of the lateral hole-shaped opening 20 of the thin tube 10 (in FIGS. 1, 2, 4, 5, and 6). It is integrally molded with the holder 14 so as to be located in the left direction).

FIG. 6 is a schematic diagram of a sample suction system. When the moving means (not shown) of the holder 14 operates, the thin tubes 10 and 12 move forward to the left, and the tip of the thin tube 12 hits the stopper 52 made of rubber or the like. When it further advances, the blade 18 cuts the stopper. Next thin tube
The tip of 10 hits the stopper and cuts with blade 16. Then, first, the opening 22 reaches the inside of the sample container 50. Narrow tube 12 is for ventilation
30 communicates with the atmosphere in the cleaning tank 46. For this reason,
If the inside of the sample container 50 has a negative pressure (pressure lower than atmospheric pressure), air is supplied from the outside through the ventilation pipe 30 and the thin tube 12 to approach atmospheric pressure. If the inside of the sample container 50 has a positive pressure (pressure higher than atmospheric pressure), the sample or air is pushed out to the outside through the thin tube 12 and the ventilation pipe 30, and approaches the atmospheric pressure. As a case where the blood pressure is negative, it is considered that blood is collected from a person with a thin blood vessel using a vacuum blood collection tube. Also, as a case of positive pressure, it is possible that the stopper was opened and then closed again. After a while, the opening 20 of the thin tube 10 will also become the sample container 50.
Reach in. The thin tube 10 is connected to a syringe 36 by a pipe 34. When the syringe 36 performs the suction operation, a predetermined amount of the sample is sucked from the sample container in the atmospheric pressure state, and the sample is quantitatively collected by the metering device 38. At the same time, the same amount of air is supplied from the thin tube 12 into the sample container. Therefore, the sample is sucked smoothly with little resistance. When the suction operation is completed,
The capillaries 10 and 12 retract (move to the left in FIGS. 1, 2, 4, 5, and 6) and are removed from the stopper 52. The thin tubes 10 and 12 that have been unplugged are drawn so that their openings 20 and 22 are located in the cleaning tank 46. When the syringe 36 performs the cleaning operation, the sample remaining in the flow path is pushed by the cleaning liquid and the opening
It is discharged from 20 and washed. The thin pipe 12 and the ventilation pipe 30 are cleaned by operating the pump 40 connected to the thin pipe 12 and the ventilation pipe 30 through the pipe 32 to supply the cleaning liquid. Similarly, the air pressure source 44 connected to the thin tube 12 and the ventilation pipe 30 operates to completely remove the cleaning liquid remaining in the flow path.

If the opening 22 of the thin tube 12 is behind the opening 20 of the thin tube 10 (to the right in FIGS. 1, 2, 4, 5, and 6), when the inside of the sample container is under negative pressure, the cleaning liquid in the pipe 34 is used. Is drawn into the sample container, which causes a problem that the sample is contaminated. Even if the pipe 34 is provided with an air layer, a small amount of cleaning liquid is mixed. On the contrary, in the case of positive pressure, the sample is pushed into the pipe 34.

In this way, by providing the opening 22 of the ventilation thin tube 12 in front of the opening 20 of the sample thin tube 10, a fixed amount of the sample can be used without any problem whether the inside of the sample container is negative pressure or positive pressure. Can be sucked. Further, as shown in FIG. 3, two thin tubes for piercing the stopper 52 are provided, and pierce locations slightly apart from each other from the center of the stopper. Therefore, even if the same sample container is installed, the location where the pierce is made every time it is installed. Will change. For this reason, even if it is pierced multiple times, the part does not become brittle and the fragments of the plug do not occur.

Next, the results of the durability test of the sample suction thin tube of the present invention will be described. As a test, the vacuum blood collection tube was continuously pierced into the rubber stopper. However, each vacuum blood collection tube was pierced 5 times. After puncturing 110,000 times, microscopic observation was performed, but the wear of the tip of the thin tube was 0.5 mm or less, which was 10 times more wear resistant than the conventional thin tube. In addition, there was no clogging due to rubber residue.

[Effect of device]

Since the sample suction thin tube of the present invention is configured as described above, it has the following effects.

(A) In order to improve wear resistance, a thin tube is subjected to a film treatment to form a film, so that the hardness is increased and the thin tube can be made thinner than before, and since a blade is provided at the tip, the thin tube is Can pierce while opening the tap. By these, the frictional force generated between the thin tube and the plug can be reduced. Further, since the two thin tubes are provided, the place where the stopper is pierced changes every time the sample container is installed, and therefore the stopper does not become brittle even if the measurement is repeated many times.
Therefore, the generation of broken pieces of the plug such as rubber residue is almost eliminated.

(B) Since the opening at the tip of the thin tube is a lateral hole, it is possible to prevent clogging due to broken pieces of the plug.

(C) The life of the thin tube can be remarkably extended by forming a film by applying a film treatment to enhance wear resistance.

(D) Since the sample has a ventilating thin tube, the inside of the sample container can be brought to the atmospheric pressure state, and the sample can be smoothly sucked. Moreover, since the opening of the ventilating thin tube is located in front of the opening of the sample thin tube, the opening of the sample thin tube is immersed in the sample while the inside of the sample container is close to the atmospheric pressure, and therefore the contamination is prevented. It is possible to always suck a fixed amount of sample without problems such as the above.

[Brief description of drawings]

FIG. 1 is a partial cross-sectional right side view showing an embodiment of the sample suction thin tube of the present invention, FIG. 2 is a bottom view thereof, and FIG. 3 is a front view thereof.
FIG. 4 is an enlarged view of the tip portion of the sample capillary (enlarged view of portion A in FIG. 2), FIG. 5 is a sectional view taken along line BB in FIG. 4, and FIG. 6 is a sample suction capillary of the present invention. It is a schematic diagram of a sample suction system using. 10 …… Sample thin tube, 12 …… Ventilation thin tube, 14 …… Holder,
16, 18 ... Blade, 20, 22 ... Opening, 24 ... Encapsulation member, 26 ...
… Adhesive, 28 …… Passage, 29 …… Coating, 30, 32, 34 …… Piping, 36 …… Syringe, 38 …… Metering device, 40 …… Pump,
44 …… Pneumatic source, 46 …… Cleaning tank, 50 …… Sample container, 52 ……
plug

Claims (1)

[Scope of utility model registration request] 1. A sample thin tube for sucking a sample, a ventilation thin tube for aeration, and a holder for holding these two thin tubes, each of which has a blade at the tip thereof. Provide a horizontal hole-like opening in the cylindrical portion near the tips of the two capillaries, and seal the area from the tip to the opening with a sealing member and an adhesive, and at the tip part including the blades and openings of the two capillaries. A sample suction thin tube characterized in that a coating having excellent wear resistance is formed, and the opening of the ventilation thin tube is located in front of the opening of the sample thin tube.