JPH07138173A - Therapeutic agent for dermatopathy such as atopic dermatitis - Google Patents

Abstract

PURPOSE:To obtain a therapeutic agent having great therapeutic effects on various hardly treatable dermatopathies such as atopic dermatitis without any side effect thereon. CONSTITUTION:This therapeutic agent for various dermatopathies is obtained by suitably combining gelanicals such as Houttuyniae Herba, Moutan Cortex, Scutellariae Radix, Bupleuri Radix, Nepetae Herba, Paeoniae Radix, Rehmanniae Rhizoma, Coptidis Rhizoma, Phellodendri Cortex, Gardeniae Fructus, Rhei Rhizoma, Seseleos Radix and Atractylodis Rhizoma, decocting the galenicals with a vegetable oil such as olive oil, removing solid substances by filtering, etc., the resultant extract solution, providing an essence, placing horse oil and beeswax therein, cooling the prepared mixture while stirring the mixture, preparing a plaster and using the resultant plaster as a principal ingredient.

Description

Detailed Description of the Invention

[0001]

This invention is used as a therapeutic drug for skin diseases of atopic dermatitis. It is also used as a treatment for stomatitis, acne, ear canal, and other skin disorders.

[0002]

2. Description of the Related Art Conventionally, Japanese Patent Application No. 5-9 filed by the same person
No. 3519, Japanese Patent Application No. 5-105881, Japanese Patent Application No. 5-1
There are remedies for skin diseases such as atopic dermatitis disclosed in Japanese Patent Application No. 41135 and Japanese Patent Application No. 5-204408. The herbal medicines that compose these therapeutic agents include one part that is not part of the pharmacopoeia.
Similarly, there is a corticosteroid hormone drug as a remedy for atopic dermatitis, etc., but it has to be discontinued because of side effects of this drug such as systemic symptoms, blackening of the skin and thinning of the skin. There are many things that can not be done.

[0003]

Therefore, it is an object to make all the crude drugs constituting the therapeutic drug for skin diseases such as atopic dermatitis belong to the Japanese Pharmacopoeia. And atopic dermatitis,
It acts on stomatitis, acne, otitis externa, and other skin diseases to suppress itchiness, no side effects, and more effectively suppress inflammation due to allergies, etc., and to obtain a therapeutic drug with a greater effect. In the case of corticosteroid hormones, which are currently considered to be effective therapeutic agents for atopic dermatitis, there is no choice but to discontinue their use due to side effects such as systemic symptoms, blackening of the skin and thinning of the skin. In many cases, an external preparation that can replace this is strongly desired.

[0004]

[Means for Solving the Problems] As a first means, deer peony, button pie, sardine, swordfish, peony,
Various skins containing effective combination of extracts of horse mackerel, such as olive oil and other vegetable oils, which are obtained by appropriately combining crude drugs such as dioxin, laurel, psyllium, sardine, rhubarb, sardine, etc. Remedy for disease. As a second means, it may be obtained by appropriately combining crude drugs such as deer yak, button pie, sardine, psycho, cacao, peony, sardine, sardine, sardine, sanshishi, rhubarb, sardine, etc. and simmering them in vegetable oil such as olive oil. Remedy for various skin diseases whose active ingredient is a combination of the extract and horse oil. As a third means, a proper combination of crude drugs such as juuyaku, button pie, sardine, psycho, keigai, peony, dio, laurel, sardine, sanshishi, rhubarb, spruce, soup, and sausage, is boiled with vegetable oil such as olive oil. A remedy for various skin diseases containing a combination of the extract obtained and horse oil as an active ingredient. As a fourth means
Ougon, Psycho, Keigai, Fern, Peony,
A remedy for various skin diseases whose effective main ingredient is a combination of crude drugs such as dioxin, rhubarb, gendine, juniper, etc., which are boiled with vegetable oil such as olive oil and horse oil. As a fifth means,
A remedy for various skin diseases whose effective main ingredient is a combination of herbal medicines such as juuyaku, button pie, sardine and the like, and an extract obtained by boiling these with vegetable oil such as olive oil and horse oil. As a sixth means, an effective main ingredient is a combination of crude drugs such as sardine, turkey, swordfish, kaygae, licorice, etc., and a mixture of horse oil and an extract obtained by boiling these with vegetable oils such as olive oil. A remedy for various skin diseases. As a seventh means, an effective main ingredient is a combination of horse oil and an extract obtained by boiling crude oil such as deer yam, pothampi, swordfish, psycho, kaygae, etc., which are boiled with vegetable oil such as olive oil. Remedies for various skin diseases. As an eighth means, deer, button pie, psycho,
Kayigai, peony, swordfish, oren, sage,
Treatment of various skin diseases whose effective main component is a combination of extracts of bovine oil such as olive oil and the like, which are obtained by appropriately combining crude drugs such as sardine, rhubarb, spruce, soup, and salamander. medicine. 9th
As a means for the treatment of various skin diseases, an effective main component is a combination of crude drugs such as sardines, pipiens, and psychos, and an extract obtained by boiling these with vegetable oils such as olive oil and horse oil. . As a tenth means, various kinds of skin whose effective main ingredient is a combination of herbal medicines such as sardines, pipiens, psychos, kaygae, etc., obtained by boiling these with vegetable oils such as olive oil and horse oil Remedy for disease. As 11th means, 1st means, 2nd means, 3rd means, 4th means, 5th means, 6th means, 7th means 8th
A therapeutic agent for various skin diseases, which comprises as an effective main component an extract obtained by boiling off a vegetable oil such as olive oil by appropriately combining the crude drugs of the above-mentioned means, the ninth means, or the tenth means. As a twelfth means, the first means, the second
, The third means, the fourth means, the fifth means, the sixth means, the seventh means, the eighth means, the ninth means, or the tenth means in each case are appropriately combined in each case. Together,
A remedy for various skin diseases whose active ingredient is an extract obtained by boiling off horse oil. As 13th means, 1st means, 2nd means, 3rd means, 4th means, 5th means, 6th means, 7th means, 8th means, 9th means , A therapeutic agent for various skin diseases, which comprises, as an active principle, a combination of the extract obtained by boiling out of the tenth means, the eleventh means and the twelfth means with hinthiol. Atopic dermatitis has many causes and various symptoms. In order to ameliorate these skin symptoms, we have invented an ointment that combines the effective pharmacological actions of Chinese herbal medicines. The above crude drug is assembled based on the following. 1. It has antiphlogistic, antibacterial and other pharmacological effects. It has a pharmacological effect such as suppression of vascular hyperpermeability. Has a pharmacological action such as detoxification: Ougon 4. Has a pharmacological action such as anti-itch: Kaigai 5. It has anti-allergic and other pharmacological effects: Psycho Based on these, the following crude drugs are appropriately combined. 1. It has pharmacological actions such as anti-inflammatory and detoxification: rhubarb, laurel, psyllium, ginseng sardine, spruce 2. It has anti-itch and other pharmacological actions: Bow-fu, Soujutsu, Salamander, juniper. It has pharmacological actions such as skin hydration: peony, diocin 4. Antiallergic and anti-inflammatory action, etc .: Licorice Other herbal medicines having a pharmacological action or having the same pharmacological action as described above can be appropriately combined. And further moisturizing the skin,
By combining horse oil, which has other effects such as strong penetration into skin tissue, and vegetable oil, the therapeutic effect is further enhanced.

[0005]

[Effect] By lightly applying the therapeutic agent of the present invention locally or by spreading it on gauze or paper and applying it, there are no side effects on atopic dermatitis and more effective inflammation due to allergies. As it is suppressed and the itch is suppressed, deterioration of the affected area due to scratches or the like can be prevented, and the therapeutic effect is further increased. The skin can be restored to normal, and the color of the skin that has been discolored by using a corticosteroid hormone can be restored to normal. Even for stomatitis, acne, ear canal, itch, and other skin diseases, there are no side effects, and allergies, inflammations, etc. are effectively suppressed, and the therapeutic effect is greater.

[0006]

Example 1 An extract obtained by boiling off olive oil with an appropriate combination of crude drugs such as sardine, pearl oyster, sardine, caulis, peony, sardine, sardine, sardine, sardine, rhubarb, sardine, etc. The solid matter is removed by other methods to obtain an extract. Horse oil and beeswax are added to this, dissolved, stirred and cooled to prepare a plaster, which is a therapeutic agent for various skin diseases. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 g of button beetle, 10 g of sardine, 5 g of peony, 10 g of peony, 1 ginger
It is preferred to use 0 g, 5 g of laurel, 3 g of psyllium, 5 g of sardine, 10 g of rhubarb, 10 g of sardine, and 10 g of sojutsu. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Juyaku 20g, Buttonpig 10g, Oogon 10g, Keigai 5g, Peonies 10g, Zeou 10g, Coptis 5g, Oataku 3g,
5 g of sardines, 10 g of rhubarb, 10 g of sardines, and 10 g of soup nuts were added to olive oil 500c at 140 ° C
The extract obtained by boiling for about 5 minutes at c is filtered to obtain an extract. Then, when the temperature of the extract is about 80 to 100 ° C, 100 g of beeswax and 400 g of horse oil are added and dissolved, and the drug is made by cooling while stirring.

[0007]

EXAMPLE 2 Olive oil in Example 1 was replaced with other vegetable oils such as sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil and corn oil.

[0008]

Example 3 The olive oil in Example 1 was replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0009]

Fourth Embodiment In the first embodiment, the second embodiment, the third embodiment,
A combination of hinokitiol (a component of vegetable oil) with the extract obtained by filtering the extract obtained by boiling and removing solids by other methods.

[0010]

[Embodiment 5] Embodiment 1, Embodiment 2, Embodiment 3, Embodiment 4
Beeswax in vaseline or other base.

[0011]

[Example 6] An extract obtained by boiling off olive oil with an appropriate combination of crude drugs such as sardine, pearl oyster, sardine, syco, kaygai, peony, sardine, sardine, sardine, sanshishi, rhubarb, sardine, etc. Is removed by filtration and other methods to obtain an extract. Put horse oil and beeswax in this and dissolve,
A remedy for various skin diseases whose main component is a plaster that is cooled with stirring. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 buttons
g, Ougon 10g, Psycho 10g, Keigai 5g, Peonies 10g, Sioux 10g, Ouren 5g, Oataku 3g, Sanshishi 5g, Rhinoceros 10g, Bowfu 10
It is preferable to use it in a ratio of 10 g of soy sauce. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown.
Juyaku 20g, Buttonpig 10g, Ougon 10g,
Psycho 10g, Keigai 5g, Peonies 10g, Sioux 10g, Coptis 5g, Oataku 3g, Sanshishi 5
g, rhubarb 10g, bow-fu 10g, sojutsu 10
g of the crude drug is boiled in 500 cc of olive oil at about 140 ° C. for about 5 minutes, and the extract obtained is filtered to obtain an extract. Then, when the temperature of the extract is about 80 to 100 ° C, 100 g of beeswax and 400 g of horse oil are added and dissolved, and the drug is made by cooling while stirring.

[0012]

EXAMPLE 7 Olive oil in Example 6 was replaced with other vegetable oils such as sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil and corn oil.

[0013]

[Embodiment 8] The olive oil of Embodiment 6 is replaced with other vegetable oils such as α-linolenic acid based perilla oil and perilla oil.

[0014]

[Embodiment 9] In Embodiment 6, Embodiment 7, and Embodiment 8,
A combination of hinokitiol (a component of vegetable oil) with the extract obtained by filtering the extract obtained by boiling and removing solids by other methods.

[0015]

[Embodiment 10] The beeswax of Embodiment 6, Embodiment 7, Embodiment 8, and Embodiment 9 is used as petrolatum or other base.

[0016]

[Embodiment 11] Properly combining crude drugs such as sardine, pearl oyster, sardine, psycho, kayigai, peony, sardine, sardine, sardine, sanshishi, rhubarb, spruce, soup, and salam, and simmering them in olive oil. The extract is obtained by filtering the extracted solution and removing solids by other methods. Horse oil and beeswax are added to this, dissolved, stirred and cooled to prepare a plaster, which is a therapeutic agent for various skin diseases. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 g of beetpi, 10 g of sardine, 10 g of psycho, 5 g of cayx, 10 g of peony, 10 g of dio, and 5 of aulen.
It is preferable to use g, 3 g of oat, 5 g of sashimi, 10 g of rhubarb, 3 g of spruce, 10 g of soup nuts, 3 g of salamander. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Juyaku 20g, 1 button
0g, Ougon 10g, Psycho 10g, Keigai 5g,
Peony 10g, diorhea 10g, laurel 5g, lobster 3g, sardine 5g, rhubarb 10g, spruce 3
g, Sojutsu 10g, Peppermint 3g about 14
The extract obtained by boiling for 5 minutes with 500 cc of olive oil at 0 ° C. is filtered to obtain an extract. Then, when the temperature of the extract is about 80 to 100 ° C, 100 g of beeswax and 400 g of horse oil are added and dissolved, and the drug is made by cooling while stirring.

[0017]

Example 12 Olive oil in Example 11 was replaced with sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0018]

EXAMPLE 13 Olive oil in Example 11 was replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0019]

[Example 14] In Examples 11, 12, and 13, the extracts obtained by boiling were filtered, and the solids were removed by other methods to obtain extracts, each containing hinokitiol (a component of vegetable oil). A combination.

[0020]

[Embodiment 15] Embodiment 11, Embodiment 12, Embodiment 13,
The thing which used the beeswax in Example 14 as vaseline or other bases.

[0021]

[Example 16] Properly combining crude drugs such as juuyaku, button pie, sardine, psycho, kayga, licorice, peony, dio, rhododendron, gendine, juniper, etc., and filtering these extracts obtained by boiling them with olive oil. The solid matter is removed by the method of 1 to obtain an extract. Horse oil and beeswax are added to this, dissolved, stirred and cooled to prepare a plaster, which is a therapeutic agent for various skin diseases. The above herbal medicine can be used in an appropriate ratio, but it is 20 g of deer, 20 g of peony, 10 g of sardine, 10 g of psycho, 5 g of calyx, 5 g of licorice, 10 g of peony, 10 g of dio, 10 g of rhubarb, 10 gendine.
It is preferable to use it in a ratio of 10 g of gram and 10 g of jelly. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. 20 g of deer, 10 g of peony, 10 g of gut, 10 g of psycho, 5 g of calyx, 5 g of licorice, 10 g of peony, 10 g of dio, 10 g of rhubarb, 10 gendins
g, 10 g of juniper herbal medicine 5 olive oil at about 140 ℃
The extract obtained by boiling at 00 cc for about 5 minutes is filtered to obtain an extract. Then, when the temperature of the extract is about 80 to 100 ° C, 100 g of beeswax and 400 g of horse oil are added and dissolved, and the drug is made by cooling while stirring.

[0022]

Example 17 Olive oil in Example 16 was replaced with sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0023]

[Embodiment 18] The olive oil of Embodiment 16 is replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0024]

[Example 19] Extracts obtained by boiling the extracts obtained in Examples 16, 17 and 18 were filtered, and solids were removed by other methods to obtain extracts, and hinokitiol (a component of vegetable oil), respectively. A combination of.

[0025]

[Embodiment 20] Embodiment 16, Embodiment 17, Embodiment 18,
The beeswax of Example 19 was used as petrolatum or other base.

[0026]

Twenty-first Embodiment A crude drug such as syrup, pipiens, and swordfish are appropriately combined, these are boiled with olive oil, the extract obtained is filtered, and the solid matter is removed by other methods to obtain an extract. Put horse oil and beeswax in this and dissolve,
A remedy for various skin diseases whose main component is a plaster that is cooled with stirring. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 buttons
It is preferable to use it in a ratio of 10 g of Ogone. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. An extract obtained by boiling 20 g of deer yak, 10 g of peony, 10 g of sorghum in 500 cc of olive oil at about 140 ° C. for about 5 minutes, and filtering the obtained extract solution to obtain an extract. Then, when the temperature of the extract is about 80 to 100 ° C, 100 g of beeswax and 400 g of horse oil are added and dissolved, and the drug is made by cooling while stirring.

[0027]

[Example 22] Olive oil in Example 21 was converted to sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0028]

Twenty-third Embodiment A case where the olive oil in the twenty-first embodiment is replaced with other vegetable oil such as α-linolenic acid-based perilla oil and perilla oil.

[0029]

[Example 24] Extracts obtained by boiling the extracts obtained in Examples 21, 22 and 23 were filtered, and solid substances were removed by other methods to obtain hinokitiol (a component of vegetable oil). A combination of.

[0030]

[Embodiment 25] Embodiment 21, Embodiment 22, Embodiment 23,
The beeswax in Example 24 was used as petrolatum or other base.

[0031]

Twenty-sixth Embodiment A crude drug such as syrup, pearl oyster, sardine, mussel, liquorice, etc. is appropriately combined, these are boiled in olive oil, the extract obtained is filtered, and the solid matter is removed by another method to obtain an extract. . Horse oil and beeswax are added to this, dissolved, stirred and cooled to prepare a plaster, which is a therapeutic agent for various skin diseases. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 g of button pie, 10 g of sardine, and 5 ginger
g, and licorice is 5 g. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. A crude drug of 20 g of deer, 20 g of peony, 10 g of sardine, 5 g of calyx, and 5 g of licorice was boiled in 500 cc of olive oil at about 140 ° C. for about 5 minutes to obtain an extract by filtering. And the temperature of the extract is about 80-100 ℃
At the time, 100 g of beeswax and 400 g of horse oil were added and dissolved, and the drug was made by cooling with stirring.

[0032]

[Example 27] Olive oil in Example 26 was converted into sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0033]

[Embodiment 28] The olive oil of Embodiment 26 is replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0034]

[Example 29] Extracts obtained by removing the solid matter by filtration and other methods in Examples 26, 27 and 28 were added to the extracts obtained to obtain hinokitiol (a component of vegetable oil). A combination of.

[0035]

[Embodiment 30] Embodiment 26, Embodiment 27, Embodiment 28,
The thing which used the beeswax in Example 29 for petrolatum or other bases.

[0036]

[Embodiment 31] Properly combining crude drugs such as mulberry, pearl oyster, sardine, psyche, cabbage, etc., these are boiled with olive oil, the extract obtained is filtered, and the solid matter is removed by other methods to obtain an extract. . Horse oil and beeswax are added to this, dissolved, stirred and cooled to prepare a plaster, which is a therapeutic agent for various skin diseases. The above herbal medicines can be used in an appropriate ratio, but
0g, Buttonpig 10g, Ougon 10g, Psycho 10
It is preferable to use g and 5 g of keikai. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Extracts are obtained by filtering the extract obtained by boiling a crude drug of 20 g of deer, 20 g of peony, 10 g of sardine, 10 g of psycho, and 5 g of cabbage in 500 cc of olive oil at about 140 ° C. for about 5 minutes to obtain an extract. And the temperature of the extract is about 80-100 ℃
At the time, 100 g of beeswax and 400 g of horse oil were added and dissolved, and the drug was made by cooling with stirring.

[0037]

[Example 32] Olive oil in Example 31 was converted to sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0038]

[Thirty-third Embodiment] The olive oil of the thirty-first embodiment is replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0039]

[Example 34] Extracts obtained by boiling off the extracts obtained in Examples 31, 32 and 33 were filtered, and solids were removed by other methods to obtain hinokitiol (a component of vegetable oil). A combination of.

[0040]

[Embodiment 35] Embodiment 31, Embodiment 32, Embodiment 33,
The beeswax of Example 34 was used as petrolatum or other base.

[0041]

[Example 36] Extract obtained by simmering these in olive oil by appropriately combining crude drugs such as scrotum, button pipi, psycho, cacao, peony, sardine, laurel, sage, sardine, rhubarb, spruce, soup, and salam. The liquid is filtered, and the solid matter is removed by other methods to obtain an extract. Put horse oil and beeswax in this and dissolve,
A remedy for various skin diseases whose main component is a plaster that is cooled with stirring. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 buttons
g, Psycho 10g, Keigai 5g, Peony 10g,
10 g of dio, 5 g of citrus plant, 3 g of psyllium, 5 g of sardine, 10 g of rhubarb, 5 g of spruce, 10 gauze
It is preferable to use g and ginseng at a ratio of 5 g. Further, any other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. 20 g of deer, 10 g of peony, 10 g of psyche, 5 g of peony, 10 g of peony, 10 g of peony, 5 g of lauren, 3 g of sardine, 5 g of sausage, 10 g of rhubarb,
A crude drug of 5 g of spruce, 10 g of soup, and 5 g of salamander is boiled in 500 cc of olive oil at about 140 ° C. for about 5 minutes to obtain an extract by filtering the extract. And when the temperature of the extract is about 80-100 ° C, 100 g of beeswax and horse oil 4
A drug made by adding 00g, dissolving and cooling with stirring.

[0042]

Example 37 Olive oil in Example 36 was replaced with sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0043]

[Example 38] The olive oil of Example 36 was replaced with other vegetable oils such as α-linolenic acid based perilla oil and perilla oil.

[0044]

[Example 39] Extracts obtained by boiling off the extracts obtained in Example 36, Example 37, and Example 38 were filtered, and solids were removed by other methods to obtain hinokitiol (a component of vegetable oil). A combination of.

[0045]

[Example 40] Example 36, Example 37, Example 38,
The beeswax of Example 39 was used as petrolatum or other base.

[0046]

[Example 41] Crude drugs such as mulberry, peony, and psycho were properly combined, and these were boiled with olive oil to obtain an extract, which was then filtered to remove solids and obtain an extract. Horse oil and beeswax are added to this, dissolved, stirred and cooled to prepare a plaster, which is a therapeutic agent for various skin diseases. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 buttons
It is preferable to use g and Psycho 10 g. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Extracts are obtained by boiling 20 g of deer yam, 10 g of peony, and 10 g of psyche in 100 cc of olive oil at about 140 ° C. for about 5 minutes, and filtering the resulting extract. And when the temperature of the extract is about 80-100 ° C, 100 g of beeswax and horse oil 4
A drug made by adding 00g, dissolving and cooling with stirring.

[0047]

[Example 42] Olive oil in Example 41 was converted into sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0048]

[Example 43] The olive oil of Example 41 was replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0049]

Example 44 In Examples 41, 42 and 43, the extracts obtained by boiling were filtered, and the solids were removed by other methods to obtain extracts, and hinokitiol (a component of vegetable oil), respectively. A combination of.

[0050]

[Embodiment 45] Embodiment 41, embodiment 42, embodiment 43,
The beeswax in Example 44 was used as petrolatum or other base.

[0051]

[Embodiment 46] Crude drugs such as sardines, peony, psychosis, caulis, and the like are appropriately combined, and these are boiled with olive oil, and the obtained extract is filtered and solids are removed by other methods to obtain an extract. Horse oil and beeswax are added to this, dissolved, stirred and cooled to prepare a plaster, which is a therapeutic agent for various skin diseases. The above herbal medicines can be used in an appropriate ratio, but it is preferable to use them in a ratio of 20 g of deer yak, 10 g of button pie, 10 g of psyche, and 5 g of mussel. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Juyaku 20g, 1 button
About 0g, Psycho 10g, 5g of cabbage, about 140 ℃
The extract obtained by boiling off with olive oil of 500 cc for about 5 minutes is filtered to obtain an extract. And the temperature of the extract is about 80
A drug made by adding 100 g of beeswax and 400 g of horse oil at -100 ° C, dissolving and cooling with stirring.

[0052]

[Example 47] The olive oil of Example 46 was converted to sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0053]

[Embodiment 48] Olive oil of Embodiment 46 is replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0054]

[Example 49] Extracts obtained by boiling the extracts obtained in Examples 46, 47 and 48 were filtered, and solids were removed by other methods to obtain hinokitiol (a component of vegetable oil). A combination of.

[0055]

[Embodiment 50] Embodiment 46, Embodiment 47, Embodiment 48,
The beeswax of Example 49 was used as petrolatum or other base.

[0056]

[Example 51] An extract obtained by boiling off olive oil with an appropriate combination of crude drugs such as sardine, pearl oyster, sardine, caulis striata, peony, sardine, sardine, sardine, sardine, rhubarb, sardine, etc. The solid matter is removed by other methods to obtain an extract. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 g of beetpi and 1 gong
0g, Keigai 5g, Peony 10g, Sioux 10
It is preferable to use g, 5 g of laurel, 3 g of psyllium, 5 g of sardine, 10 g of rhubarb, 10 g of sardine, and 10 g of sojutsu. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Juyaku 20g, Buttonpig 10g, Oogon 10g, Keigai 5g, Peonies 10g, Zeou 10g, Coptis 5g, Oataku 3g,
5 g of sardines, 10 g of rhubarb, 10 g of sardines, and 10 g of soup nuts were added to olive oil 500c at 140 ° C
The extract obtained by boiling for about 5 minutes at c is filtered to obtain an extract. Then, when the temperature of the extract is about 80 to 100 ° C., 500 g of beeswax is added and dissolved, and the drug is made by cooling while stirring.

[0057]

[Embodiment 52] Olive oil in Embodiment 51 is replaced with sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0058]

[Example 53] The olive oil of Example 51 is replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0059]

[Example 54] Hinokitiol (a component of vegetable oil) was added to the extract obtained by filtering the extract obtained by boiling in Example 51, Example 52, and Example 53 and removing the solid matter by other methods. A combination of.

[0060]

[Embodiment 55] Embodiment 51, Embodiment 52, Embodiment 53,
The beeswax of Example 54 was used as petrolatum or other base.

[0061]

[Example 56] An extract obtained by simmering these in olive oil by appropriately combining crude drugs such as sardine, pearl oyster, sardine, syco, kaygai, peony, sardine, sardine, sardine, sanshishi, rhubarb, sardine, etc. Is removed by filtration and other methods to obtain an extract. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but there are 20 g of deer, 20 g of peony, 10 g of sardine, 10 g of psyche, 5 g of cayx, 10 g of peony, 10 g of sardine, 5 g of oat, 3 of oat.
g, 5 g of sardines, 10 g of rhubarb, 10 g of bow-fu,
It is preferably used in a proportion of 10 g of soup. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Juyaku 20g, Buttonpig 10g, Oogon 10g, Psycho 10g, Keigai 5g, Peony 10g, Diou 1
A crude drug of 0 g, 5 g of laurel, 3 g of psyllium, 5 g of sardine, 10 g of rhubarb, 10 g of sardine, 10 g of soup nut was boiled in 500 cc of olive oil at about 140 ° C. for about 5 minutes to obtain an extract. Then, when the temperature of the extract is about 80 to 100 ° C., 500 g of beeswax is added and dissolved, and the drug is made by cooling while stirring.

[0062]

[Embodiment 57] Olive oil in Embodiment 56 is replaced with sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0063]

[Embodiment 58] The olive oil of Embodiment 56 is replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0064]

[Example 59] Extracts obtained by removing the solids by filtration and other methods in Examples 56, 57, and 58 were added to extracts obtained by hinokitiol (a component of vegetable oil), respectively. A combination of.

[0065]

[Embodiment 60] Embodiment 56, Embodiment 57, Embodiment 58,
The beeswax of Example 59 was used as petrolatum or other base.

[0066]

[Example 61] Obtained by boiling off these oils with olive oil in appropriate combination with herbal medicines such as juuyaku, button pie, sardine, psycho, kaygai, peony, sardine, laurel, sardine, sanshishi, rhubarb, spruce, soup, and salamander. The extract is obtained by filtering the extracted solution and removing solids by other methods. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 g of button pie, 10 g of sardine, 5 g of psyche, 5 g of kayga,
Peony 10g, diorhea 10g, laurel 5g, lobster 3g, sardine 5g, rhubarb 10g, spruce 5
It is preferable to use g, soy sauce 10 g, and sausage 5 g. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Juyaku 20g, button pick 10g,
Ougon 10g, Psycho 5g, Keigai 5g, Peonies 10g, Diou 10g, Ouren 5g, Oataku 3
g, 5 g of sardine, 10 g of rhubarb, 5 g of spruce, 10 g of sorghum, and 5 g of salamander were boiled in 500 cc of olive oil at about 140 ° C. for about 5 minutes to obtain an extract, which was filtered to obtain an extract. And the temperature of the extract is about 80-1
A drug made by adding 500 g of beeswax at 00 ° C, dissolving and cooling with stirring.

[0067]

[Example 62] Olive oil in Example 61 was replaced with sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0068]

Example 63 The olive oil of Example 61 is replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0069]

[Example 64] Extracts obtained by boiling off the extract obtained in Example 61, Example 62, and Example 63 were filtered, and solids were removed by other methods to obtain hinokitiol (a component of vegetable oil). A combination of.

[0070]

[Embodiment 65] Embodiment 61, embodiment 62, embodiment 63,
The beeswax of Example 64 was used as petrolatum or other base.

[0071]

[Embodiment 66] Properly combining crude drugs such as sycamore, button pie, sardine, psycho, cacao, liquorice, peony, diorhea, rhubarb, gendine, juniper, etc., these were boiled with olive oil, and the extract obtained was filtered. The solid matter is removed by the method of 1 to obtain an extract. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 g of button pie, 10 g of sardine, 10 psycho
g, 5 g of Keikai, 5 g of licorice, 10 g of peony,
It is preferable to use 10 g of dioxin, 10 g of rhubarb, 10 g of gendine, and 10 g of juniper. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Juyaku 20g, Buttonpig 10g, Ougon 10g, Psycho 1
0g, Keigai 5g, Licorice 5g, Peony 10
g, 10g of dio, 10g of rhubarb, 10g of gendine,
10 g of juniper herbal medicine 500 olive oil of about 140 ℃
The extract obtained by boiling for 5 minutes with cc is filtered to obtain an extract. Then, when the temperature of the extract is about 80 to 100 ° C., 500 g of beeswax is added and dissolved, and the drug is made by cooling while stirring.

[0072]

[Embodiment 67] The olive oil used in embodiment 66 is sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0073]

[Example 68] The olive oil of Example 66 was replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0074]

[Embodiment 69] Extracts obtained by boiling off the extracts obtained in Examples 66, 67 and 68 are filtered, and solid substances are removed by other methods to obtain hinokitiol (a component of vegetable oil). A combination of.

[0075]

[Embodiment 70] Embodiment 66, Embodiment 67, Embodiment 68,
The beeswax of Example 69 was used as petrolatum or other base.

[0076]

[Example 71] Crude drugs such as syrup, pearl oyster, and sardine are appropriately combined, and these are boiled in olive oil to obtain an extract, which is filtered to remove solids and obtain an extract. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but it is preferable to use them in a ratio of 20 g of deer yak, 10 g of button pie, and 10 g of augon. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. An extract obtained by boiling 20 g of deer yak, 10 g of peony, 10 g of sorghum in 500 cc of olive oil at about 140 ° C. for about 5 minutes, and filtering the obtained extract solution to obtain an extract. And when the temperature of the extract is about 80-100 ° C, add 500 g of beeswax to dissolve it,
A drug made by cooling while stirring.

[0077]

[Example 72] Olive oil in Example 71 was replaced with sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0078]

[Example 73] The olive oil of Example 71 was replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0079]

[Example 74] In Examples 71, 72, and 73, the extracts obtained by boiling were filtered, and the solids were removed by other methods to obtain extracts, and hinokitiol (a component of vegetable oil), respectively. A combination of.

[0080]

[Embodiment 75] Embodiment 71, Embodiment 72, Embodiment 73,
The beeswax of Example 74 was used as petrolatum or other base.

[0066]

[Embodiment 76] Crude drugs such as mulberry, pearl oyster, sardine, caulis liquor, licorice and the like are appropriately combined, and these are boiled with olive oil, the extract obtained is filtered, and the solid matter is removed by another method to obtain an extract. . A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicine can be used in an appropriate ratio, but 20 g of deer yak,
It is preferable to use 10 g of button bean, 10 g of sardine, 5 g of mussel, and 5 g of liquorice. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Juyaku 20g, Buttonpig 10g, Oogon 10g, Keigai 5
g, licorice 5 g, crude oil 50 at about 140 ° C
The extract obtained by boiling at 0 cc for about 5 minutes is filtered to obtain an extract. And when the temperature of the extract is about 80-100 ° C,
A drug made by adding 500 g of beeswax, dissolving and cooling with stirring.

[0082]

[Example 77] Olive oil in Example 76 was converted to sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0083]

[Embodiment 78] Olive oil of Embodiment 76 is replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0084]

[Example 79] In Examples 76, 77 and 78, the extracts obtained by boiling were filtered, and the solids were removed by other methods to obtain extracts, and hinokitiol (a component of vegetable oil) was added. A combination of.

[0085]

[Embodiment 80] Embodiment 76, Embodiment 77, Embodiment 78,
The beeswax in Example 79 was used as petrolatum or other base.

[0086]

[Embodiment 81] Properly combining crude drugs such as mulberry, pearl oyster, sardine, psyllium, and pearl oyster, boiling these with olive oil, filtering the extract obtained, and removing the solid matter by other methods to obtain an extract. . A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but it is preferable to use them in a ratio of 20 g of deer yak, 10 g of button beetle, 10 g of sardine, 10 g of psyche, and 5 g of mussel. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Goldfish 20g, Tanjin 10g, Ougon 10g Psycho 10
g, cabbage 5g crude drug 50 olive oil at about 140 ℃
The extract obtained by boiling at 0 cc for about 5 minutes is filtered to obtain an extract. And when the temperature of the extract is about 80-100 ° C,
A drug made by adding 500 g of beeswax, dissolving and cooling with stirring.

[0087]

Example 82 A combination of ru (a component of vegetable oil). The olive oil used in Example 81 was sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil, corn oil or other vegetable oil.

[0088]

[Example 83] The olive oil of Example 81 was replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0089]

[Embodiment 84] Extracts obtained by removing the solid matter by filtration and other methods in Examples 81, 82 and 83 were used to obtain hinokitiol (a component of vegetable oil). A combination of.

[0090]

[Embodiment 85] Embodiment 81, Embodiment 82, Embodiment 83,
The beeswax of Example 84 was used as petrolatum or other base.

[0091]

[Example 86] Extract obtained by simmering these in olive oil by appropriately combining crude drugs such as sardine, pearl oyster, psycho, cacao, peony, sardine, laurel, psyllium, sardine, rhubarb, spruce, soup, and salamander. The liquid is filtered, and the solid matter is removed by other methods to obtain an extract. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 g of button pie, 10 g of psyche, 5 g of peony, 10 g of peony, 10 g of dio, 5 g of laurel, 3 g of oak, 5 g of sardine,
It is preferable to use 10 g of rhubarb, 5 g of spruce, 10 g of soup, and 5 g of salamander. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Juyaku 20g, Buttonpig 10g, Psycho 10g, Keigai 5
g, peony 10g, dioxin 10g, ouren 5
g, Oataku 3g, sushi 5g, rhubarb 10g,
A crude drug of 5 g of spruce, 10 g of soup, and 5 g of salamander is boiled in 500 cc of olive oil at about 140 ° C. for about 5 minutes to obtain an extract by filtering the extract. Then, when the temperature of the extract is about 80 to 100 ° C., 500 g of beeswax is added and dissolved, and the drug is made by cooling while stirring.

[0092]

[Embodiment 87] The olive oil used in Embodiment 86 is sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0093]

[Embodiment 88] The vegetable oil of the embodiment 86 except that α-linolenic acid-based perilla oil, perilla oil, and other vegetable oils are used.

[0094]

[Embodiment 89] The extracts obtained by boiling the extracts obtained in Examples 86, 87 and 88 by filtration and removing the solids by other methods were added to hinokitiol (a component of vegetable oil). A combination of.

[0095]

[Embodiment 90] Embodiment 86, embodiment 87, embodiment 88,
The beeswax of Example 89 based on petrolatum or other base. An extract is obtained by appropriately combining crude drugs such as rye yam, button pie, and psycho, boiling these with olive oil, filtering the obtained extract, and removing the solid matter by other methods. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but it is preferable to use them in a ratio of 20 g of deer, 20 g of peony, 10 g of psycho. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, one example of production of the drug of the present invention will be shown. Approximately 14 herbal medicines of 20g of deer, 10g of peony, 10g of psycho
The extract obtained by boiling for 5 minutes with 500 cc of olive oil at 0 ° C. is filtered to obtain an extract. Then, when the temperature of the extract is about 80 to 100 ° C., 500 g of beeswax is added and dissolved, and the drug is made by cooling while stirring.

[0097]

Example 92 Olive oil in Example 91 was converted to sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0098]

[Example 93] The olive oil of Example 91 is replaced with other vegetable oils such as α-linolenic acid-based perilla oil and perilla oil.

[0099]

[Example 94] Extracts obtained by removing the solid matter by filtration and other methods in Examples 91, 92, and 93 were used to obtain hinokitiol (a component of vegetable oil). A combination of.

[0100]

[Embodiment 95] Embodiment 91, Embodiment 92, Embodiment 93,
The beeswax of Example 94 was used as petrolatum or other base.

[0101]

[Example 96] Crude drugs such as syrup, pearl oyster, psyllium, and pearl oyster are combined as appropriate, and these are boiled with olive oil, and the extract obtained is filtered and solids are removed by other methods to obtain an extract. Add beeswax to this and dissolve,
A remedy for various skin diseases whose main component is a plaster that is cooled with stirring. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 buttons
It is preferable to use g, Psycho 10 g, and Keigai 5 g. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used. Next, 1 of manufacture of the medicine of this invention
Here is an example: An extract obtained by boiling 20 g of deer, 20 g of peony, 10 g of psyche, and 5 g of cabbage in 500 cc of olive oil at about 140 ° C. for about 5 minutes and filtering the extract is obtained. Then, when the temperature of the extract is about 80 to 100 ° C., 500 g of beeswax is added and dissolved, and the drug is made by cooling while stirring.

[0102]

[Example 97] Olive oil in Example 96 was converted to sesame oil, safflower oil, rapeseed oil, evening primrose oil, sunflower oil,
Other vegetable oils such as corn oil.

[0103]

[Embodiment 98] The vegetable oil of Example 96 which is olive oil such as α-linolenic acid-based perilla oil and perilla oil.

[0104]

[Example 99] Extracts obtained by boiling off the extracts obtained in Example 96, Example 97, and Example 98 were filtered, and solids were removed by other methods to obtain hinokitiol (a component of vegetable oil). A combination of.

[0105]

[Embodiment 100] Embodiment 91, embodiment 92, embodiment 9
3, The beeswax of Example 94 was used as petrolatum or other base.

[0106]

[Example 101] An extract obtained by boiling these oils out of horses by appropriately combining crude drugs such as sardine, pearl oyster, sardine, caulis, peony, sardine, sardine, sardine, sardine, rhubarb, sardine, etc. Is removed by filtration and other methods to obtain an extract. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 g of beetpi, 10 gong
g, Keigai 5g, Peonies 10g, Sioux 10g,
It is preferable to use 5 g of laurel, 3 g of psyllium, 5 g of sardine, 10 g of rhubarb, 10 g of sardine, and 10 g of soup jujube. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used.

[0107]

[Example 102] A combination of hinokitiol (a component of vegetable oil) with an extract obtained by filtering the extract obtained by boiling and removing solids by other methods in Example 101.

[0108]

[Example 103] The beeswax of Examples 101 and 102 used as vaseline or other base.

[0109]

[Example 104] Obtained by boiling these oils out of horses by appropriately combining herbal medicines such as daikon yak, pearl oyster, swordfish, psycho, kayigai, peony, sardine, sardine, rye, sanshishi, rhubarb, sardine, etc. The extract is obtained by filtering the extract by filtration or other methods. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in appropriate proportions, but there are 20 g of deer yak, 10 g of peony, 10 g of sardine, 10 g of psycho, 5 g of peony, 10 g of peony, 10 g of dio, 5 g of oat, 3 g of oat,
It is preferable to use 5 g of sardines, 10 g of rhubarb, 10 g of sardines, and 10 g of soup. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used.

[0110]

[Example 105] A combination of hinokitiol (a component of vegetable oil) with the extract obtained by filtering the extract obtained by boiling and removing the solid matter by another method in Example 104.

[0111]

[Example 106] A product in which the beeswax in Examples 104 and 105 is used as vaseline or another base.

[0112]

[Embodiment 107] A proper combination of crude drugs such as sardine, white pipi, swordfish, psycho, kayigai, peony, sardine, sardine, sardine, sardine, rhubarb, spruce, soup, and salamander is boiled in horse oil. The extract obtained is filtered to remove solid matter by other methods to obtain an extract. Add beeswax to this and dissolve,
A remedy for various skin diseases whose main component is a plaster that is cooled with stirring. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 buttons
g, Oogon 10g, Psycho 10g, Keigai 5g, Peonies 10g, Ziog 10g, Coptis 5g, Oataku 3g, Sanshishi 5g, Rhinoceros 10g, Spruce 5g,
It is preferable to use 10 g of Soujutsu and 5 g of Sausage. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used.

[0113]

[Example 108] A combination of hinokitiol (a component of vegetable oil) with the extract obtained by filtering the extract obtained by boiling and removing solids by other methods in Example 107.

[00114]

[Example 109] The beeswax of Examples 107 and 108 used as vaseline or other base.

[0115]

[Embodiment 110] A herbal medicine such as sycamore, button pie, sardine, psycho, kayigai, licorice, peony, dio, rhubarb, gendine, juniper, etc., is properly combined,
The extract obtained by boiling these off with horse oil is filtered, and solids are removed by other methods to obtain an extract. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but
0g, Buttonpig 10g, Ougon 10g, Psycho 10
g, 5 g of Keikai, 5 g of licorice, 10 g of peony,
It is preferable to use 10 g of dioxin, 10 g of rhubarb, 10 g of gendine, and 10 g of juniper. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used.

[0116]

[Example 111] A combination of hinokitiol (a component of vegetable oil) with an extract obtained by filtering the extract obtained by boiling and removing the solid matter by another method in Example 110.

[0117]

[Example 112] The beeswax of Examples 110 and 111 was used as petrolatum or other base.

[0118]

[Embodiment 113] A herbal medicine such as goldfish, tanjin, swordfish, etc. is appropriately combined, these are boiled with horse oil, the extract obtained is filtered, and the solid matter is removed by other methods to obtain an extract. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but it is preferable to use them in a ratio of 20 g of deer yak, 10 g of button pie, and 10 g of augon. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used.

[0119]

[Example 114] A combination of hinokitiol (a component of vegetable oil) with an extract obtained by filtering the extract obtained by boiling and removing the solid matter by another method in Example 113.

[0120]

[Example 115] The beeswax of Examples 113 and 114 was used as petrolatum or other base.

[0121]

[Example 116] Crude drugs such as sardine, sea squirrel, swordfish, oyster, licorice and the like are appropriately combined, these are boiled with horse oil, the extract obtained is filtered, and the solid matter is removed by other methods to obtain an extract. To get A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but it is preferable to use them in a ratio of 20 g of deer yak, 10 g of button beetle, 10 g of sardine, 5 g of mussel, and 5 g of licorice. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used.

[0122]

[Example 117] A combination of hinokitiol (a component of vegetable oil) with the extract obtained by filtering the extract obtained by boiling and removing solids by other methods in Example 116.

[0123]

[Embodiment 118] A product in which the beeswax in Embodiments 116 and 117 is used as vaseline or another base.

[0124]

[Embodiment 119] A crude drug such as sardine, turkey, swordfish, psycho, kaygae, etc. is properly combined, these are boiled with horse oil, the extract obtained is filtered, and the solid matter is removed by other methods to obtain an extract. To get A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but it is preferable to use them in a ratio of 20 g of deer yak, 10 g of button beetle, 10 g of sardine, 10 g of psyche, and 5 g of mussel. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used.

[0125]

[Example 120] A combination of hinokitiol (a component of vegetable oil) with the extract obtained by filtering the extract obtained by boiling and removing the solid matter by another method in Example 119.

[0096]

[Example 121] The beeswax of Examples 119 and 120 was used as petrolatum or other base.

[0127]

[Embodiment 122] Obtained by boiling off these oils of horse by appropriately combining crude drugs such as sycamore, button pipi, psycho, kaygai, peony, sardine, lauren, sage, sushi, rhubarb, spruce, soup, and salamander. The extract is obtained by filtering the extracted solution and removing solids by other methods. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 g of button pie, 10 g of psycho, 5 g of peony, 10 g of peony, 10 g of dio
It is preferable to use them in the proportions of g, 5 g of laurel, 3 g of oat, 5 g of sardine, 10 g of rhubarb, 5 g of spruce, 10 g of soup nut, 5 g of salamander. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used.

[0128]

[Example 123] A combination of hinokitiol (a component of vegetable oil) with an extract obtained by filtering the extract obtained by boiling and removing the solid matter by another method in Example 122.

[00129]

EXAMPLE 124 The beeswax of Examples 122 and 123 was used as petrolatum or other base.

[0130]

[Embodiment 125] Crude drugs such as sardines, peony, and psycho are properly combined, these are boiled with horse oil, the extract obtained is filtered, and solids are removed by other methods to obtain an extract. A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 g of button pie, 1 psycho
It is preferably used in a proportion of 0 g. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used.

[0131]

[Example 126] A combination of hinokitiol (a component of vegetable oil) with the extract obtained by filtering the extract obtained by boiling and removing the solid matter by another method in Example 125.

[0132]

[Example 127] The beeswax of Examples 125 and 126 used as vaseline or other base.

[0133]

[Embodiment 128] A herbal medicine such as mulberry, white pipi, psycho, kaygae, etc. is properly combined, these are boiled with horse oil, the extract obtained is filtered, and the solid matter is removed by other methods to obtain an extract. . A remedy for various skin diseases that contains beeswax as a main ingredient, which is melted and cooled while stirring to make a plaster. The above herbal medicines can be used in an appropriate ratio, but 20 g of deer yak, 10 buttons
It is preferable to use g, Psycho 10 g, and Keigai 5 g. In addition, other crude drug having the same pharmacological action as the above crude drug may be appropriately used.

[0134]

[Example 129] A combination of hinokitiol (a component of vegetable oil) with the extract obtained by filtering the extract obtained by boiling and removing the solid matter by another method in Example 128.

[0135]

(Example 130) The beeswax of Examples 128 and 129 was used as petrolatum or other base.

[0131]

EFFECT OF THE INVENTION By using these drugs for atopic dermatitis, which is difficult to treat, there are no side effects, the inflammation due to allergies can be more effectively suppressed, and the itchiness of the affected area can be suppressed. It is possible to prevent deterioration of the affected area due to the treatment, and it is possible to perform treatment that is much more effective than before. Then, the skin can be restored to normal, and the skin that has been discolored due to the side effect of using the corticosteroid hormone can be restored to normal. In addition, the use of these drugs has no side effects on stomatitis, acne, ear canal, itch, and other skin diseases, and more effectively acts on inflammation and other symptoms, and thus has a great therapeutic effect.

Claims (31)

[Claims] 1. A combination of the herbal medicines of juuyaku, button pie, swordfish, kayga, peony, dio, lauren, sage, sardine, rhubarb, sardine, and soup, which are boiled with vegetable oil, and horse oil are combined. A remedy for various skin diseases, characterized in that 2. An extract obtained by boiling botanical oils of horse mackerel, pearl oyster, pearl oyster, sycamore, oyster oyster, peony, sardine, laurel, pearl oyster, sardine, rhubarb, pearl oyster, eucalyptus, and horse oil. A therapeutic agent for various skin diseases, which comprises a combination of the compounds as an active ingredient. 3. An extract obtained by boiling botanical oils together with a herbal medicine of sycamore, button pie, sardine, psycho, cacao, peony, sardine, citrus cabbage, sardine, sardine, rhubarb, spruce, eucalyptus. A therapeutic agent for various skin diseases, which comprises a combination of horse oil as an active ingredient. 4. A combination of an extract obtained by boiling these vegetable oils with horse oil, which is a combination of the herbal medicines of juuyaku, button pie, sardine, psycho, kayga, licorice, peony, dio, rhododendron, gendine and juniper. A therapeutic agent for various skin diseases, which comprises: 5. A treatment for various skin diseases, characterized in that an effective main ingredient is a combination of a herbal medicine of saccharum serrata, button pipi, and sardine, and an extract obtained by boiling these off with vegetable oil and horse oil. medicine. 6. A variety of types characterized in that an effective main component is a combination of a herbal medicine of sycamore, button pie, swordfish, kayga, and licorice, and a combination of an extract obtained by boiling these off with vegetable oil and horse oil. Remedies for skin disorders. 7. A variety of types characterized in that an effective main component is a combination of a herbal medicine of sycamore, button pie, swordfish, psycho, and kayga, and a combination of an extract obtained by boiling these off with vegetable oil and horse oil. Remedies for skin disorders. 8. A herbal extract of horse mackerel, white pipi, psycho, kaygai, peony, sardine, laurel, sage, sardine, rhubarb, spruce, soup, and salamander, which are boiled with vegetable oil to obtain an extract of horse and horse. A therapeutic agent for various skin diseases, which comprises a combination of oils as an active ingredient. 9. A treatment for various skin diseases, characterized in that an effective main ingredient is a combination of a herbal medicine of Yaku yak, button pie, and psychophyllum, and a combination of an extract obtained by boiling these with vegetable oil and horse oil. medicine. 10. A variety of skin diseases characterized by using a combination of crude drugs of syrup, pipiens, psychophylla, and pearl oysters, and combining an extract obtained by boiling these with vegetable oil and horse oil as an active ingredient. Remedies for. 11. An extract obtained by boiling botanical oils in combination with a crude drug of juuyaku, button pie, swordfish, kaygae, peony, sardine, laurel, sage, sardine, rhubarb, sardine, and eucalyptus, is used as an active ingredient. A therapeutic agent for various skin diseases characterized by the following: 12. An effective main component of an extract obtained by combining botanicals of sardine, white pipi, swordfish, psycho, kayigai, peony, sardine, sardine, sardine, sardine, rhubarb, sardine, and sorghum, and simmering them with vegetable oil. A therapeutic agent for various skin diseases, which comprises: 13. An extract obtained by boiling these oils with vegetable oil by combining crude drugs such as sardine, pearl oyster, sardine, psycho, kayigai, peony, sardine, citrus, sardine, sardine, rhubarb, spruce, soup, and salamander. A therapeutic agent for various skin diseases, which is characterized by having an active main component. 14. A combination of the herbal medicines of sardine, white peony, sardine, psycho, cacao, liquorice, peony, dio, rhododendron, gendine and juniper, which are boiled with vegetable oil and used as an effective main component. A remedy for various characteristic skin diseases. 15. A therapeutic agent for various skin diseases, characterized in that an extract obtained by boiling them in vegetable oil is used as an active ingredient in combination with crude drugs of syrup, peony, and sardine. 16. A therapeutic agent for various skin diseases, which comprises a combination of crude drugs of sycamore, button pie, swordfish, kaygae, and licorice, and an extract obtained by boiling these off with vegetable oil as an effective main component. 17. A therapeutic agent for various skin diseases, which comprises a combination of crude drugs of syrup, button peony, swordfish, psycho, and mussel, and an extract obtained by simmering them in vegetable oil as an active ingredient. 18. An extract obtained by combining botanicals of sardine, white pipi, psycho, kayga, peony, sardine, laurel, sage, sardine, rhubarb, spruce, soup, and salamander, and simmering them in vegetable oil. A therapeutic agent for various skin diseases, which is characterized by being an ingredient. 19. A therapeutic agent for various skin diseases, characterized in that an extract obtained by boiling them with vegetable oils, which is a combination of the herbal medicines of Japanese yam, peony, and psyche, is the active ingredient. 20. A therapeutic agent for various skin diseases, characterized in that an effective main ingredient is an extract obtained by combining botanicals of sycamore, pipiens, psychosis, and pearl oysters, and extracting these with vegetable oil. 21. An effective main ingredient is an extract obtained by combining the herbal medicines of scrotum, button pie, swordfish, kaygae, peony, sardine, laurel, sage, sardine, rhubarb, sardine, and pearl syrup, and boiling them with horse oil. A therapeutic agent for various skin diseases, which comprises: 22. An extract obtained by boiling boar oil with a combination of crude drugs of sardine, pearl oyster, sardine, psychosis, kaygai, peony, sardine, sardine, sardine, sardine, rhubarb, sardine, and soup. A remedy for various skin diseases, which is characterized by having a main component. 23. A combination of the herbal medicines of sardine, button pie, sardine, psycho, kayigai, peony, sardine, sardine, sardine, sanshishi, rhubarb, spruce, soup, and salamander, obtained by boiling these in horse oil. A therapeutic agent for various skin diseases, which comprises an extract as an effective main component. 24. An effective main ingredient is an extract obtained by decocting horse mackerel oil with a combination of crude drugs of sardine, pearl oyster, sardine, psycho, cacao, licorice, peony, dio, rhubarb, gendine, juniper. A therapeutic agent for various skin diseases characterized by the following: 25. A therapeutic agent for various skin diseases, characterized in that an effective main ingredient is an extract obtained by boiling horse mackerel oil in combination with a crude drug of syrup, button pie, and sardine. 26. A remedy for various skin diseases, characterized in that an extract obtained by boiling off horse mackerel oil from a combination of crude drugs of syrup, button pie, swordfish, caulis liquor, and licorice is used as an active ingredient. 27. A therapeutic agent for various skin diseases, characterized in that an extract obtained by boiling off horse mackerel oil from a combination of crude drugs of sycamore, button pie, swordfish, saiko, and kayiga is used as an active ingredient. 28. An extract obtained by combining the herbal medicines of juuyaku, button pipi, psycho, kaygai, peony, sardine, lauren, ouaf, sangishi, rhubarb, spruce, sowjutsu, and halibut and boiling them with horse oil. A remedy for various skin diseases, which is characterized by having an active principle. [29] A therapeutic agent for various skin diseases, characterized in that an extract obtained by boiling horse mackerel oil in combination with a crude drug of sycamore, button pie, and psychosis is an effective main component. 30. A therapeutic agent for various skin diseases, characterized in that an effective main ingredient is an extract obtained by boiling horseradish oil with a combination of crude drugs of syrup, peony, psycho, and kayga. 31. The first, second and third aspects of the claims.
Section, Section 4, Section 5, Section 6, Section 7, Section 8, Section 9.
Item, Item 10, Item 11, Item 12, Item 13, Item 14
Item, Item 15, Item 16, Item 17, Item 17, Item 18, Item 19
Item, Item 20, Item 21, Item 22, Item 23, Item 24
Item, Item 25, Item 26, Item 27, Item 28, Item 29
Item 30. The therapeutic agent for various skin diseases according to Item 30, wherein the extract obtained by boiling is combined with hinthiol.