JPH06247808A - Seed disinfectant composition - Google Patents

Abstract

PURPOSE:To obtain the subject composition as a combination of seed disinfectant(s) with certain kind(s) of antimicrobial agent, broad in antimicrobial spectrum, having stable disease injury-controlling activity even against disinfectant-resistance bacteria, giving synergistic effect, thus usable at low levels of dose. CONSTITUTION:The objective composition is a combination of at least one kind of compound selected from ergosterol biosynthesis inhibitors, cell growth inhibitors, organic and inorganic copper agents, bactericides and pyrrole-based microbisides as seed disinfectant with at least one kind of compound selected from 1,5-pentanedial, 2,5-dimethoxutetrahydrofuran, glyoxal, benzalkonium chloride, 1,2-benzoisothiazolin-3-one, 4-chloro-2-xylenol, 4-chloro-2-cresol and p- oxybenzoic esters as antibacterial agent. These active ingredients can be pharmaceutically manufactured into an emulsion stock liquor, sprayable paste, sprayable or dilutible solution, emulsion, hydrate, aqueous solution, powder or capsules. The amount of the component B to be used is suitably 0.1-10 pts.wt. per pt.wt. of the component A.

Description

Detailed Description of the Invention

[0001]

[Object of the Invention]

[0002]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a seed disinfectant composition containing a seed disinfectant and a certain antimicrobial agent as active ingredients.

[0003]

2. Description of the Related Art Seed disinfectants are widely and commonly used for controlling various seed-borne diseases and soil-borne diseases. The seed disinfectant is applied to seeds of various crops by dressing, dipping, spraying or the like. Examples of seed disinfectants include ergosterol biosynthesis inhibitors, cell division inhibitors, and organic / inorganic copper agents. Bactericidal agents, pyrrole fungicides, etc. are used.

[0004]

However, the above-mentioned seed disinfecting agents have limited efficacy of diseases, and resistant bacteria have appeared in some of the pathogenic bacteria that have conventionally exhibited antibacterial activity. Deterioration is becoming a problem.

In view of such circumstances, the present inventor conducted various studies to develop a seed disinfectant having a broad antibacterial spectrum and a stable disease control effect against the above-mentioned seed disinfectant drug-resistant bacteria. The present invention has been completed by finding that a synergistic effect can be exhibited and a low dose can be used by using a certain antimicrobial agent together with a seed disinfectant.

[0006]

[Constitution of the invention]

[0007]

The present invention provides an ergosterol biosynthesis inhibitor, a cell division inhibitor, an organic / inorganic copper agent,
One or more compounds selected from among bactericides and pyrrole fungicides (hereinafter referred to as compound (I));
A seed disinfectant composition comprising, as an active ingredient, one or more compounds selected from the group of the following antimicrobial agents (hereinafter referred to as compound (II)).

(Antimicrobial group) 1,5-pentanedial, 2,5-dimethoxytetrahydrofuran, glyoxal, benzalkonium chloride, 1,2-benzisothiazolin-3-one, 4-chloro-2-xylenol,
4-Chloro-2-cresol, paraoxybenzoic acid ester The ergosterol biosynthesis inhibitor, the cell division inhibitor, the organic / inorganic copper agent, the bactericide, and the pyrrole fungicide, which are one of the components of the present invention, It includes agents used for seed treatment as seed disinfectants.

In the above, the ergosterol biosynthesis inhibitor is a drug having an activity of inhibiting the fungal ergosterol biosynthesis system, and examples thereof include triflumizole,
Triadimenol, pefurazoate, prochlorads,
Mention may be made of triadimefon, hexaconazole, cycloconazole, metconazole and etaconazole.

In the above, the cell division inhibitor is an agent having an activity of inhibiting fungal cell division, and examples thereof include benomyl, thiophanate methyl, and thiabendazole.

In the above, the organic / inorganic copper agent is an agent having copper in the molecule, and examples thereof include cupric hydroxide, basic copper chloride and copper nonylphenol sulfonate.

In the above, the bactericidal agent is a drug used for controlling bacterial diseases, for example,
Oxolinic acid and streptomycin can be mentioned.

In the above, the pyrrole fungicide is a drug having a pyrrole ring in the molecule, for example, 4-
(2,2-difluoro-1,3-benzodioxole-
4-yl) pyrrole-3-carbonitrile can be mentioned.

The antimicrobial agent used as one component of the present invention includes agents used as highly safe industrial antibacterial and antifungal agents, or those used as agricultural bactericides. Any of those usually used as an antimicrobial agent can be used. For example, alcohols, aldehydes, phenols, quaternary ammonium salts, thiazoles, isothiazolones, epoxides, guanidines, organic-inorganic copper agents, etc., preferably,
1,5-pentanedial, 2,5-dimethoxytetrahydrofuran, glyoxal, benzalkonium chloride, 1,2-benzisothiazolin-3-one, 4-chloro-2-xylenol, 4-chloro-2-cresol, paraoxy Benzoic acid ester, more preferably 1,5-pentanedial and 1,2-benzisothiazolin-3-one.

In the present invention, one kind or two or more kinds of the above-mentioned antimicrobial agents can be used in combination.

[0016]

The antimicrobial agent, which is one of the components of the present invention, does not have a disease controlling effect by itself, but when mixed with a seed disinfectant, the seed disinfecting effect is remarkably enhanced. And show a synergistic effect.

Diseases in which the combination of the present invention exerts excellent efficacy include, for example, rice blast, bacillus seedling disease, sesame leaf blight, rice blight bacterial disease, seedling wilt bacterial disease, and naked wheat smut of wheat. , Fusarium head blight, powdery mildew, and seedling blight of vegetables, etc., but the sterilization spectrum is not limited to these.

The compounding agent of the present invention is used together with an auxiliary agent usually used in the field of formulation. The active ingredients of the seed disinfectant (I) and the antimicrobial agent (II) can be prepared by known methods, for example, emulsion stock solutions, sprayable pastes, sprayable or dilutable solutions, emulsions, wettable powders, aqueous solutions, powders, For example, it is formulated into a capsule or the like using a polymer substance.

The above-mentioned preparations can be used as they are or after being diluted with water or the like and subjected to seed dressing treatment, seed dipping treatment, spray treatment and the like. It can also be mixed with other seed treatment agents.

The blending ratio of the seed disinfectant (I) and the antimicrobial agent (II), which are the active ingredients of the composition of the present invention, can be varied within a relatively wide range, but the usual seed disinfectant (I) 1
Antimicrobial agent (II) is 0.01 to 100 parts by weight.
Parts by weight, preferably in the range of 0.1 to 10 parts by weight.

The application rate of the composition of the present invention varies depending on the mixing ratio of active ingredients, weather conditions, formulation form, application time, method, place, target disease, target crop, etc., but usually 1 kg of seeds as the total amount of active ingredients. For example, about 0.001 to about 5
0 g, preferably about 0.01 to about 10 g can be used.

[0022]

EXAMPLES The present invention will be described in more detail below with reference to formulation examples and test examples, but the compounds, additives and their compounding ratios in the formulation examples are not limited to these. In addition,% indicating the usage rate of formulation examples is% by weight unless otherwise specified.

In the following description, Ia to Ig and IIa to IIh represent the following compounds, respectively.

Ia: triflumizole Ib: triadimenol Ic: pefurazoate Id: benomyl Ie: oxolinic acid If: 4- (2,2-difluoro-1,3-benzodioxol-4-yl) pyrrole-3 -Carbonitrile Ig: cupric hydroxide IIa: 1,5-pentanedial IIb: 2,5-dimethoxytetrahydrofuran IIc: glyoxal IId: benzalkonium chloride IIe: 1,2-benzisothiazolin-3-one IIf: 4-chloro-2-xylenol IIg: 4-chloro-2-cresol IIh: paraoxybenzoic acid ester

[0025]

[Formulation example]

[0026]

[Formulation Example 1] (Wettable powder) 20 parts of compound Id, compound I
20 parts of Ie, 3 parts of calcium ligninsulfonate, 2 parts of sodium lauryl sulfate and the balance of synthetic silicon hydroxide were well pulverized and mixed to obtain a wettable powder.

[0027]

[Formulation Example 2] (Wettable powder) 20 parts of compound Ia, compound I
20 parts of Ie, 3 parts of calcium ligninsulfonate, 2 parts of sodium lauryl sulfate and the balance of synthetic silicon hydroxide were well pulverized and mixed to obtain a wettable powder.

[0028]

[Formulation Example 3] (Wettable powder) 10 parts of compound Ie, compound I
20 parts of Ie, 3 parts of calcium lignin sulfonate, 2 parts of sodium lauryl sulfate and the balance of synthetic silicon hydroxide were well pulverized and mixed to obtain a wettable powder.

[0029]

TEST EXAMPLE Next, the test example shows that the composition of the present invention is useful as a seed disinfectant.

[0030]

[Test Example 1] Rice sapling seedling disease control test Rice buds (cultivar Tanginbozu) contaminated with benomyl-resistant, low-sensitivity triflumizole rice scabbed seedling disease fungus (Gibberella fujikuroi) were used in Preparation Examples 1, 2, 3 and The present invention prepared according to them, 400 times as much as the wettable powder, 2
After soaking for 4 hours, the seedlings were sowed and seeded in a plastic pot filled with seedling-raising soil after germination. Then, it was cultivated in a greenhouse for 21 days, and the diseased seedling rate was examined. The results are shown in Table 1.

[0031]

[Table 1] Rice sapling disease control test (in the table, the numbers indicate diseased seedling rates (%).)

[0032]

[Test Example 2] Rice seedling wilting bacterial disease control test A rice paddy rice (cultivar Koshihikari) inoculated and infected with Pseudomonus plantarii was prepared using Formulation Example 1,
2, 3 and 4 of the wettable powder of the present invention prepared according to them
It was soaked in a diluted solution of 00 times for 24 hours, and seeded in a plastic pot filled with seedling cultivation soil after soaking and germination. Then, the seedlings were germinated at 30 ° C. for 3 days and then cultivated in a greenhouse for 18 days to examine the diseased seedling rate. The results are shown in Table 2.

[0033]

[Table 2] Rice seedling killing bacterial disease control test (in the table, the numbers indicate diseased seedling rates (%).)

[0034]

[Test Example 3] Control test for wheat smut disease Wheat seeds (Ustilago tritici) inoculated and infected with wheat seeds (cultivar Norin 61) were prepared with a prescribed amount of the wettable powder of the present invention prepared according to the formulation example. The seedlings were subjected to dressing treatment and seeded in a plastic pot filled with seedling cultivation soil. Then, it was cultivated in a greenhouse for 21 days, and the diseased seedling rate was examined. The results are shown in Table 3.

[0035]

[Table 3] Wheat bare smut control test (in the table, the numbers indicate the diseased seedling rate (%).)

Continuation of the front page (51) Int.Cl. ⁵ Identification number Office reference number FI technical indication (A01N 43/52 43:80) (A01N 43/90 43:80) (72) Inventor Shigehiro Kato Shiga Prefecture 1041 Yasu-cho, Yasu-cho, Yasu-cho In-house (72) Inventor Mikio Tsuda In-house 1041 Yasu-cho, Yasu-cho, Yasu-gun, Shiga In-house (72) In-house Kenji Yasui 1041 Yasu-cho, Yasu-cho, Yasu-gun In-house

Claims (1)

[Claims] Claims: 1. One or more compounds selected from ergosterol biosynthesis inhibitors, cell division inhibitors, organic / inorganic copper agents, bactericides, and pyrrole fungicides, and the following antimicrobial agents: A seed disinfectant composition comprising as an active ingredient one or more compounds selected from the group of. (Antimicrobial agent group) 1,5-pentanedial, 2,5-
Dimethoxytetrahydrofuran, glyoxal, benzalkonium chloride, 1,2-benzisothiazoline-3
-One, 4-chloro-2-xylenol, 4-chloro-
2-cresol, paraoxybenzoic acid ester