JPH06146B2 - Sustained release material encapsulation base material - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial field of application] The present invention relates to a substrate in which a sustained-release substance is internally released, and more specifically, as a bactericide, insecticide, repellent, attractant, deodorant or fragrance. The present invention relates to a base material containing a sustained-release substance, which is desired to gradually volatilize and maintain its efficacy for a long period of time.

[Conventional technology]

As is well known, sustained-release substances such as bactericides are used in various fields, and it is desirable that these substances are gradually volatilized so that their effects last as long as possible. Conventionally, these sustained-release substances are used as they are or by supporting them on an appropriate air-permeable base material, but since the sustained-release substance is in direct contact with air, its volatilization is rapid and it is difficult to last for a long time. It was.

In addition, recently, in each device having a blower such as a heater or a cooler, a base material carrying a sustained-release substance is installed in a part of a blower path. For example, as shown in Fig. 1, a kind of package was developed in which a granular material (2) of a sustained release substance was enclosed in an air permeable bag-like material (1), and this package was directly attached to a heater or cooler in the air passage. It is a thing. It should be noted that (3) in FIG. 1 is a part in which the bag-shaped material is sandwiched between two parts, and there is an air-permeable base material (4) having a fine mesh so that other sustained-release substances do not volatilize by blowing air. ), The fine-grained sustained-release substance-encapsulating bag (5) pre-wrapped therein is stored. Even in such a package, the sustained-release substance is in direct contact with the air, so that its sustaining effect is short.

[Problems to be solved by the invention]

The problem to be solved by the present invention is to solve the above-mentioned difficulties of this kind of sustained-release substance, in other words, to provide a base material containing a sustained-release substance having a large sustained effect. is there.

[Means for solving problems]

The above problems can be achieved by once encapsulating the sustained-release substance in an inorganic microcapsule, granulating this with a binder resin, and supporting this granular material on an air-permeable substrate. That is, the present invention relates to a sustained-release substance-encapsulating base material characterized in that an air-permeable base material is loaded with a granular material comprising inorganic microcapsules containing a sustained-release substance and a binder resin.

[Structure and Action of Invention]

The sustained-release substance-containing base material according to the present invention is basically as follows.

(A) Encapsulating the sustained-release substance in inorganic microcapsules, (b) Granulating the microcapsules of (a) above with a binder resin to form granules, and (c) Air permeability of these granules. It consists of being carried on a base material.

In the present invention, since the sustained-release substance is encapsulated in the inorganic microcapsules, the sustained-release substance is gradually volatilized, and its sustaining effect is remarkably improved. Further, by granulating the inorganic microcapsules encapsulating the sustained-release microcapsules together with the binder resin, volatilization of the sustained-release substance is further suppressed, and the sustained-release effect is further lengthened, and the particulate matter is supported. As the air permeable base material, it is possible to use a coarse material to the extent that the particulate matter does not fall off or volatilize from between the base materials. This facilitates the flow of air between the substrates,
The sustained release substance is effectively diffused by air. It should be noted that when an extremely dense material is used as the base material, the air is not sufficiently circulated and the sustained release substance is volatilized, but the diffusion thereof is insufficient.

Hereinafter, the present invention will be described in detail in the order of (A) to (C).

The sustained-release substance is not particularly limited, and any substance that can be volatilized and exerts its effect can be used. For example, a bactericidal agent, an insecticide, a fragrance, a deodorant, and another disinfectant, Examples thereof include repellents for insects such as cockroaches and mosquitoes, attractants for pheromones and the like. As the inorganic microcapsules for encapsulating the sustained-release substance, microcapsules made of an inorganic material can be used, and typical examples thereof include the following.

In the present invention, examples of the inorganic material forming the outer wall of the microcapsule (referred to as a wall substance) include the following, and one or more of them are used.

Alkaline earth metal carbonates such as calcium carbonate, barium carbonate, magnesium carbonate, etc.

Alkaline earth metal silicates ... Calcium silicate, barium silicate, magnesium silicate, etc.

Alkaline earth metal phosphates ... Calcium phosphate, barium phosphate, magnesium phosphate, etc.

Alkaline earth metal sulfates, such as calcium sulfate, barium sulfate, magnesium sulfate, etc.

Metal oxide: Silica (silicic acid anhydride), titanium oxide, iron oxide, cobalt oxide, zinc oxide, nickel oxide, manganese oxide, aluminum oxide (alumina), etc.

Metal hydroxide: Iron hydroxide, nickel hydroxide, aluminum hydroxide, calcium hydroxide, chromium hydroxide, etc.

Silicates other than alkaline earth metals: zinc silicate, aluminum silicate, copper silicate, magnesium aluminum silicate, magnesium silicate, etc.

Carbonates other than alkaline earth metals: zinc carbonate, aluminum carbonate, cobalt carbonate, basic carbonates, nickel carbonate, etc.

The method of encapsulating the sustained-release substance in the microcapsule is not limited to a method for producing the sustained-release substance, as long as the sustained-release substance is included in the microcapsule.
For example, it can be manufactured by the following method.

A sustained-release substance is added to a 0.3 mol / -saturated aqueous solution containing at least one inorganic compound selected from alkali metal silicates, carbonates, phosphates and copper sulfate, and alkaline earth metal halides. Disperse. Then, an organic solvent having a solubility in water of preferably 5% or less is mixed to obtain W /
After being made into an O-type emulsion, it is at least one of an alkaline earth metal halide, an inorganic acid, an organic acid, an ammonium salt of an inorganic acid, an ammonium salt of an organic acid and a carbonate of an alkali metal, and the above inorganic An aqueous solution of a compound capable of forming a water-insoluble precipitate (i.e. wall material) by an aqueous reaction with the compound (concentration 0.05 mol / -saturation concentration, preferably 0.1
˜2 mol /) is mixed with the above W / O type emulsion in an amount equal to or more than the latter with respect to 100 parts by weight of the former.
Thus, spherical porous inorganic wall microcapsules containing the sustained-release substance are obtained. 5% solubility in water
The following organic solvents include hexane, decane, hexadecane, isohexane, isoheptane, and other saturated aliphatic hydrocarbons: hexene, octene, dimethylbutadiene, heptine, and other unsaturated unsaturated hydrocarbons; benzene, toluene,
Aromatic hydrocarbons such as dodecylbenzene, cymene and styrene; cyclohexane; alicyclic hydrocarbons such as cyclohexene and cyclononane are exemplified, and these are alone or
Used in combination with one or more species. Also, it does not matter if these organic solvents are mixed with alcohols or the like up to about 10% by weight. The amount of the organic solvent used is not particularly limited as long as the obtained emulsion is a W / O type, but is usually 50% by weight or more, preferably 70 to 80% by weight of the emulsion.
It is good to say The emulsification method may be a conventional method such as a stirring method or a shaking method. Upon emulsification, a known emulsifier can be added. As the emulsifier, preferably HLB
Can be used nonionic surfactants in the range of 3.5-6.0, polyoxyethyl sorbitan monooleate, polyoxyethylene sorbitan monolaurate, sorbitan monostearate, sorbitan trioleate, etc. are exemplified as typical ones. It These emulsifiers are usually used in an amount of 5% by weight or less, preferably 0.01 to 3% by weight, based on the organic solvent. Such a manufacturing method is disclosed in Japanese Examined Patent Publication No.
It can be carried out according to the procedure disclosed in Japanese Patent No. 251.

Next, in the present invention, microcapsules containing a sustained-release substance are mixed with a binder resin and granulated. In this case, the mixing ratio of both is 50% by weight or less, preferably about 5 to 40% by weight, of the microcapsules in the mixture. The average particle size of the granulated granules is about 1 to 10 mm, preferably about 3 to 7 mm. A wide variety of natural or synthetic resins can be used as the binder resin used,
Conventional synthetic resins are used. Typical examples thereof are polyvinyl chloride, polyvinylidene chloride, polyvinyl acetate, polyethylene, polypropylene, polymethylpentene, polybutene-1, polybutadiene, polystyrene, acrylonitrile resin, AS resin, ABS resin, MBS resin,
Polyphenylene ether, polyphenylene sulphate, fluororesin, silicone resin, polymethacrylstyrene, methacryl resin, polyamide, polyimide, polyimide amide, polyethylene terephthalate, polybutylene terephthalate, polycarbonate, polyvinyl alcohol, polyvinyl ether, polyacetal, polyallyl sulfone, polyarylate , Isopropylene rubber,
Further, there may be mentioned two or more kinds of copolymers of monomers constituting these resins such as polybutadiene rubber or other resins, or two or more kinds of polymer blends of these monomers or other resins.

Not only granular but also pellet-like,
Various types such as a cylindrical shape, a conical shape, a rectangular parallelepiped, and a cube are included.

The particles thus obtained are supported on an air-permeable substrate. Air permeable materials are widely used as the base material in this case, and examples thereof include woven cloth, non-woven cloth, felt, and resin base material. The means for supporting the particles is not particularly limited as long as the particles are supported on the base material. A typical means is a means in which the above-mentioned base material is formed into a bag shape and the granular material is contained inside the bag-shaped base material. For example, as shown in FIG. 2, the granular material (7) is contained in the bag-shaped base material (6).

〔Example〕

 Hereinafter, the present invention will be described in more detail with reference to Examples.

Example 1 A base material as shown in FIG. 2 was prepared. That is, a synthetic resin non-woven fabric is used as a bag-shaped base material, and a granulated product having an average particle diameter of 3 to 7 mm, which is composed of 40 parts by weight of inorganic microcapsules containing a bactericide inside and 60 parts by weight of polyvinyl chloride did. However, the inorganic microcapsules were prepared as follows.

No. 3 silicic acid 6.5 mol / 83 ml with 15 g of bactericide added 1
Sorbitan monolaurate (Sp
an-20) cyclohexane solution 1 having a concentration of 30 g /
It is put in 67 ml and emulsified by an emulsifier at 700 rpm for 1 minute. This is placed in 1.5 mol / 500 ml of ammonium bicarbonate prepared beforehand, and gently stirred for 20 minutes.

This is subjected to solid-liquid separation using a centrifugal settler.

Separate into aqueous solution (liquid) layers of bactericide, encapsulated silica (solid), solvent, reaction by-product (sodium carbonate) and unreacted ammonium bicarbonate.

Since the bactericide-containing silica thus obtained has a pH of 9.6 in a 5% slurry, the bactericide-containing silica generated in pure water is added to neutralize the silica, and 0.1 mol / apple of apple is added. Adjust to pH 5-6 with acid.

The encapsulated silica is recovered again by a centrifugal filter.

The fungicide-containing silica thus obtained has a size of 1
It was 0 to 50 μ.

[Brief description of drawings]

FIG. 1 is a schematic diagram of a conventional sustained-release substance-containing bag-shaped substrate, and FIG. 2 is a schematic diagram of a bag-shaped substrate as an example of the substrate of the present invention. 1 ... bag-like material 2 ... granules of sustained-release material 3 ... part of bag-like material 4 ... air-permeable base material 5 ... sustained-release material-containing bag 6 ... Bag-shaped base material 7 Granules 8 Microcapsules containing sustained-release substance

Claims (3)

[Claims] 1. A sustained-release substance-encapsulating base material, characterized in that an air-permeable base material is loaded with a granular material composed of inorganic microcapsules containing a sustained-release substance and a binder resin. 2. The sustained-release substance-containing base material according to claim 1, wherein the granular material is housed in a bag-like material made of an air-permeable base material. 3. The sustained-release substance according to claim 1 or 2, wherein the sustained-release substance is at least one of a bactericide, insect repellent, repellent, attractant, deodorant and fragrance. Encapsulation substrate.