JP6706465B2 - Vital sensor module - Google Patents

Description

The present embodiment relates to a vital sensor module .

When information about the human body is acquired by a sensor, a motion sensor that captures a movement or an optical sensor that obtains information by using light is used in addition to those used in a medical field and a blood glucose meter that directly measures blood itself.

The pulse wave sensor can measure the blood flow in the capillaries by using an optical sensor that comes into contact with the body surface, and can measure the pulse rate, pulse fluctuation, etc. from the change in blood flow due to the heartbeat. .. In the measurement using the optical sensor, the blood oxygen saturation level using light of two different wavelengths is used in addition to the pulse rate.

On the other hand, in order to monitor respiration, it is common to wear a breathing band on the chest or waist or an air pressure transducer or velocity meter at the nasal opening.

Japanese Patent Laid-Open No. 2012-19926 JP 2012-19928 A JP 2012-19929A JP 2012-120773 A U.S. Patent Application Publication No. 2014/0051955 JP, 2004-121668, A International Publication No. 2011/027438

However, the technique of wearing a breathing band on the chest or lower back to monitor respiration or an air pressure transducer or velocity meter at the nasal opening is extremely expensive in terms of equipment and equipment, and it is not possible for an ordinary person to wear it properly. Because it is difficult, it is necessary to visit a specialized institution and undergo an examination in an environment different from the daily living space.

In addition, these methods strongly tighten the device or device to the body, and the discomfort associated with wearing the device or device is also a serious problem.

The present embodiment aims to provide a vital sensor module capable of extracting respiratory components such as respiratory rhythm, respiratory rate, and presence/absence of breathing by paying attention to a change in pulse wave signal amplitude.

According to one aspect of this embodiment, the substrate and the surface of the substrate that is in contact with the human body are arranged so as to overlap with the center of the substrate when viewed in the first direction perpendicular to the substrate. A light emitting element, a light receiving element disposed on the surface so as to surround the light emitting element and spaced apart from the light emitting element, and a light emitting element disposed on the surface spaced apart from the light emitting element and the light receiving element. And a sensor that is in contact with the body surface of a living body, and the light emitted from the light emitting element is received by the light receiving element as reflected light returning from the inside of the living body, and the pulse wave signal intensity is based on the intensity of the reflected light. With detecting, by arranging the top and bottom peak values of the waveform of the pulse wave signal strength in time series respectively, it is possible to obtain an envelope curve that reflects the respiratory rhythm , the sensor, when worn, A pressure sensor for detecting a contact pressure between a body surface and a surface in contact therewith, wherein the pressure sensor includes a plurality of air blowing type pressure sensors, and whether the output values of the plurality of air blowing type pressure sensors are within a threshold range. There is provided a vital sensor module that determines a wearing state depending on whether it is outside a threshold range .

According to another aspect of the present embodiment, the substrate and the surface of the substrate that is a surface in contact with the human body are arranged so as to overlap with the center of the substrate when viewed in a first direction perpendicular to the substrate. And a light receiving element disposed on the surface so as to surround the light emitting element and spaced apart from the light emitting element, and disposed on the surface separately from the light emitting element and the light receiving element. The sensor is provided with, the light emitted from the light emitting element is contacted with the body surface of the living body, the reflected light returned from the inside of the living body is received by the light receiving element, and the pulse wave signal is based on the intensity of the reflected light. Along with detecting the intensity, by arranging the peak values of the top and bottom of the waveform of the pulse wave signal intensity respectively in time series, an envelope curve reflecting the respiratory rhythm can be obtained, and the sensor, when worn. The pressure sensor includes a pressure sensor that detects a contact pressure between the body surface and the surface in contact with the body surface. The pressure sensor includes a film pressure sensor, and an output value of the film pressure sensor is within a threshold range or outside the threshold range. A vital sensor module is provided in which the mounting state is determined depending on the condition, the film-shaped pressure sensor includes a piezo film, and the pressed region is capable of developing color.

According to another aspect of the present embodiment, the substrate and the surface of the substrate that is a surface in contact with the human body are arranged so as to overlap with the center of the substrate when viewed in a first direction perpendicular to the substrate. And a light receiving element disposed on the surface so as to surround the light emitting element and spaced apart from the light emitting element, and disposed on the surface separately from the light emitting element and the light receiving element. The sensor is provided with, the light emitted from the light emitting element is contacted with the body surface of the living body, the reflected light returned from the inside of the living body is received by the light receiving element, and the pulse wave signal is based on the intensity of the reflected light. Along with detecting the intensity, by arranging the peak values of the top and bottom of the waveform of the pulse wave signal intensity respectively in time series, an envelope curve reflecting the respiratory rhythm can be obtained, and the sensor, when worn. A pressure sensor for detecting a contact pressure with a surface in contact with the body surface is provided, and the pressure sensor includes a plurality of button type pressure sensors, and an output value of the plurality of button type pressure sensors is within a threshold range or a threshold value. Provided is a vital sensor module that determines the wearing state depending on whether it is out of range.

According to the present embodiment, it is possible to provide a vital sensor module capable of extracting a respiratory component such as a respiratory rhythm, a respiratory rate, and the presence/absence of respiration by paying attention to a change in the signal amplitude of a pulse wave.

(A) A schematic diagram showing the state of wireless communication with an external PC/portable terminal by mounting the vital sensor module according to the first embodiment on the inside of the forearm, and (b) relating to the first embodiment. The schematic diagram which shows a mode of wireless communication with an external PC/mobile terminal with the vital sensor module mounted on the outside of the forearm. (A) A schematic diagram showing the state of wireless communication with an external PC/portable terminal, in which the vital sensor module according to the first embodiment is mounted inside the index finger, (b) according to the first embodiment The schematic diagram which shows a mode of wireless communication with an external PC/mobile terminal with the vital sensor module mounted on the outside of the index finger. (A) A schematic diagram showing a state in which the vital sensor module according to the first embodiment is attached to the entrance of the ear canal, and (b) a vital sensor module according to the embodiment attached to the ear canal and an external PC/portable terminal. FIG. 3 is a schematic diagram showing a state of wireless communication of FIG. (A) A schematic planar configuration example of the optical sensor portion of the vital sensor module according to the first embodiment, (b) Another schematic planar configuration of the optical sensor portion of the vital sensor module according to the first embodiment Example. FIG. 5 is a schematic cross-sectional structure diagram showing a state in which the vital sensor module according to the first embodiment including the optical sensor shown in FIG. FIG. 6 is still another schematic plan configuration example of the optical sensor portion of the vital sensor module according to the first embodiment. FIG. 7 is a schematic sectional structural view taken along the line I-I of FIG. 6. FIG. 3 is a schematic bird's-eye view configuration diagram of the vital sensor module according to the first embodiment. The typical block block diagram inside the housing|casing of the vital sensor module which concerns on 1st Embodiment. The flowchart figure which shows the operating method of the vital sensor module which concerns on 1st Embodiment. The flowchart figure which shows the detailed operating method between step S6 and step S7 in FIG. In the vital sensor module which concerns on 1st Embodiment, the measurement example of the relationship between the pulse wave signal strength (a.u.) and the number S of samples. Another measurement example of the relationship between the pulse wave signal intensity (a.u.) and the number of samples S in the vital sensor module according to the first embodiment. In the vital sensor module according to the first embodiment, an example of measurement of the respiratory rate by the envelope curve of the relationship between the pulse wave signal intensity (au) and the sample number S in FIG. 12 (sample number S=1000 to 6000 (pieces)) ). In the vital sensor module according to the first embodiment, a measurement example of the respiratory frequency by the envelope of the relationship between the pulse wave signal intensity (au) and the sample number S in FIG. 12 (sample number S=6000 to 11000 (pieces)) ). In the vital sensor module which concerns on 1st Embodiment, the measurement example (sample number S=1000-8000 (pieces)) of the pulse wave signal intensity (a.u.) at the time of apnea and the sample number S. In the vital sensor module which concerns on 1st Embodiment, another measurement example (sample number S=1000-11000 (pieces)) of the pulse wave signal intensity (a.u.) at the time of apnea and the sample number S. 3 is a flowchart showing an operating method of the vital sensor module according to the first embodiment. FIG. 19 is an explanatory diagram of pulse wave signal waveforms corresponding to the operation method shown in FIG. 18. 9 is a flowchart showing another operation method of the vital sensor module according to the first embodiment. FIG. 21 is an explanatory diagram of a pulse wave signal waveform corresponding to the operation method shown in FIG. 20 is a measurement example of the relationship between the pulse wave signal intensity (a.u.) and the number of samples S during the operation of FIG. 20 in the vital sensor module according to the first embodiment. It is a pulse wave signal waveform example in the vital sensor module which concerns on a comparative example, Comprising: (a) Typical example provided with ejection wave and reflected wave, (b) Waveform example provided with an unnatural notch or an inflection point of a rising leg, (C) An example of a waveform having a systolic apex deformation/amplitude change of a reflected wave, (d) An example of waveform having an unnatural inflection line of a descending leg. It is the pattern example of the pulse wave signal waveform which needs attention in the vital sensor module which concerns on a comparative example, Comprising: (a) systolic deformation example (notch type), (b) systolic deformation example (tokasaka type), (c) expansion Period variant (ripple type). In the vital sensor module which concerns on 2nd Embodiment, the typical plane block diagram seen from the surface side which contacts a human body. In the vital sensor module which concerns on 3rd Embodiment, the typical plane block diagram seen from the surface side which contacts a human body. In the vital sensor module which concerns on 4th Embodiment, the typical plane block diagram seen from the surface side which contacts a human body. (A) A bird's-eye view of the optical sensor portion of the vital sensor module according to the fifth embodiment, (b) an explanatory view of FIG. 28( a ). (A) The bird's-eye view of the vital sensor module which concerns on 5th Embodiment, (b) Explanatory drawing of FIG. 29(a). The typical block block diagram of the vital sensor module which concerns on 5th Embodiment. The circuit block block diagram of the vital sensor module which concerns on 5th Embodiment. The flowchart figure which shows the operating method of the vital sensor module which concerns on 1st-5th embodiment. The flowchart figure which shows another operating method of the vital sensor module which concerns on 1st-5th embodiment.

Next, this embodiment will be described with reference to the drawings. In the following description of the drawings, the same or similar reference numerals are given to the same or similar parts. However, it should be noted that the drawings are schematic and the relationship between the thickness and the plane dimension, the ratio of the thickness of each layer, and the like are different from the actual ones. Therefore, specific thicknesses and dimensions should be determined in consideration of the following description. Further, it is needless to say that the drawings include portions having different dimensional relationships and ratios.

Further, the embodiments described below exemplify devices and methods for embodying the technical idea, and do not specify the material, shape, structure, arrangement, etc. of component parts to the following. .. This embodiment can be modified variously within the scope of the claims.

[First Embodiment]
(Mounting form of vital sensor module)
The vital sensor module 2 according to the first embodiment is attached to the inside of the forearm of the human body 18, and a schematic diagram showing a state of wireless communication with an external PC/mobile terminal 4 is as shown in FIG. Represented by. Further, the vital sensor module 2 according to the first embodiment is attached to the outside of the forearm of the human body 18, and a schematic diagram showing a state of wireless communication with an external PC/portable terminal 4 is shown in FIG. Is represented as As shown in FIGS. 1A and 1B, the vital sensor module 2 according to the first embodiment can be mounted on the forearm of the human body 18 via the arm strap 50.

In addition, the vital sensor module 2F according to the first embodiment is mounted inside the index finger 18F of the human body 18, and a schematic diagram showing a state of wireless communication with an external PC/portable terminal 4 is shown in FIG. It is represented as shown in. In addition, the vital sensor module 2F according to the first embodiment is attached to the outside of the index finger 18F of the human body 18, and a schematic diagram showing a state of wireless communication with an external PC/portable terminal 4 is shown in FIG. It is represented as shown in. As shown in FIGS. 2A and 2B, the vital sensor module 2F according to the first embodiment can be attached to the index finger 18F of the human body 18 via a finger strap 50F. Although an example in which the finger is attached to the forefinger 18F is shown here, the finger is not limited to the forefinger 18F and may be another finger.

A schematic diagram showing a state in which the vital sensor module 2E according to the first embodiment is attached to the entrance of the ear canal is represented as shown in FIG. 3A, and the vital sensor module according to the embodiment attached to the ear canal. A schematic diagram showing a state of wireless communication between 2E and an external PC/portable terminal 4 is represented as shown in FIG.

Furthermore, the mounting example of the vital sensor module according to the first embodiment is not limited to the forearm 18, the index finger 18F, and the ear canal entrance, and may be another human body part.

(Light sensor)
A schematic planar configuration example of the optical sensor 1 portion of the vital sensor module according to the first embodiment is shown as shown in FIG. 4A, and another schematic planar configuration example is shown in FIG. 4B. It is represented as shown in.

As shown in FIG. 4A, the optical sensor 1 portion of the vital sensor module according to the first embodiment is arranged adjacent to one light emitting element (LED; Light Emitting Diode) 12 and the LED 12. And a single light receiving element (PD: Photodetector) 14. The LED 12 and the PD 14 are arranged on the substrate 20A. The LED 12 and the PD 14 may be surrounded by a light shielding resin wall (insulating layer) 21 arranged on the substrate 20A. Here, the LED 12 can emit visible light or near infrared light. The PD 14 is a light receiving element having sensitivity in the same band as the LED 12 that emits visible light or near infrared light. When a plurality of PDs 14 are arranged, an optical filter may be provided on each of the plurality of PDs 14 for proper use. For example, one PD 14 may be provided with an optical filter so that it is sensitive to visible light and the other PD 14 is sensitive to near infrared light. The optical filter can be formed, for example, by applying it to a light receiving element or a resin package, but is not limited to this.

In addition, in the vital sensor module 2 according to the first embodiment, the LED 12 includes a green light emitting diode and can measure a pulse wave.

In addition, in the vital sensor module 2 according to the first embodiment, the LED 12 includes a red light emitting diode or an infrared light emitting diode, and can measure blood oxygen saturation.

Another configuration example of the optical sensor 1 portion of the vital sensor module according to the first embodiment is as shown in FIG. 4B, in which two LEDs 12 ₁ and 12 ₂ and LEDs 12 ₁ and 12 ₂ are adjacent to each other. And one PD 14 arranged in the same manner. The LEDs 12 ₁ and 12 ₂ and the PD 14 are arranged on the substrate 20A. Further, the LEDs 12 ₁ and 12 ₂ and the PD 14 may be surrounded by a light shielding resin wall (insulating layer) 21 arranged on the substrate 20A. Here, the LEDs 12 ₁ and 12 ₂ can emit visible light or near infrared light. Further, the PD 14 is a light receiving element having sensitivity in the same band as the LEDs 12 ₁ and 12 ₂ that emit visible light or near infrared light.

(Vital sensor module)
Further, a schematic cross-sectional structure example in a state where the vital sensor module 2 according to the first embodiment including the optical sensor 1 shown in FIG. 4A is mounted on the human body (arm) 18 is as shown in FIG. Represented by.

As shown in FIG. 5, the vital sensor module 2 according to the first embodiment is arranged, for example, in a face-down close contact with a human body (arm) 18. Although the vital sensor module 2 is in close contact with the human body (arm) 18 in the example shown in FIG. 5, the vital sensor module 2 may be disposed apart from the surface of the human body (arm) 18 by a predetermined distance. Here, the predetermined distance is, for example, within several mm.

The substrate 20A can be formed of, for example, a printed circuit board (PCB), and is arranged in the module housing 10. The memory 8A, the control integrated circuit 8B, the resistance element 8R, the capacitor 8C, and the like are arranged on the front surface (the surface on the side contacting the human body 18 is referred to as the back surface or the bottom surface) of the substrate 20A. Here, the resistance element 8R, the capacitor 8C and the like are applied to components such as a delay circuit.

Further, as shown in FIG. 5, the battery 9 may be arranged on the front surface side of the substrate 20A via a columnar resin wall (insulating wall) 21B. The battery 9 is also arranged in the module housing 10. The battery 9 and the electrodes on the substrate 20A are connected by a bonding wire 20W or the like.

Further, as shown in FIG. 5, a board 20B may be arranged on the front surface side of the board 20A and the battery 9 via a connector 6A. The board 20B is also arranged in the module housing 10. Here, the connector 6A connects between the substrates 20A and 20B.

As shown in FIG. 5, the optical sensor 1 is preferably arranged so as to project from the surface of the module housing 10.

Further, the module housing 10 may be provided with a concave curved surface shape in accordance with the shape of the human body 18 portion in the portion in contact with the human body 18 so that the close contact between the human body 18 and the optical sensor 1 is facilitated. ..

The module housing 10 according to the present embodiment has, for example, adhesiveness on the surface, and the vital sensor module 2 is configured to be attached to the human body 18 by the adhesiveness of the module housing 10. Good.

Further, the module housing 10 may be made of a material having higher flexibility than the other configuration of the vital sensor module 2, thereby improving the adhesion between the module housing 10 and the human body 18, As a result, the adhesion between the vital sensor module 2 and the human body 18 can be further improved.

When the surface of the module housing 10 is made to have an adhesive property, an extra configuration for bringing the vital sensor module 2 such as a belt into close contact with the human body 18 is not essential.

Yet another schematic planar configuration example of the portion of the optical sensor 1 arranged on the bottom surface side of the vital sensor module 2 according to the first embodiment in contact with the human body 18 is shown in FIG. A schematic sectional structure taken along the line I-I is represented as shown in FIG. 7.

As shown in FIGS. 6 and 7, the optical sensor 1 of the vital sensor module 2 according to the first embodiment has a plurality of PDs 14 ₁ arranged on the PCB 20 so that the LED 12 is arranged in the center and the periphery of the LED 12 is surrounded.・14 ₂・14 ₃・14 ₄ are arranged. In the example of FIG. 6, four PDs are arranged. In the example of FIG. 6, four PDs are arranged for one LED, but the configuration is not limited to this, and two PDs may be arranged for one LED. Further, four LEDs may be arranged for one PD. Alternatively, two LEDs may be arranged for one PD.

Further, as shown in FIGS. 6 and 7, a black light-shielding resin wall 21 is arranged on the surface of the PCB 20, and the LED 12 and PDs 14 ₁ , 14 ₂ , 14 ₃ , 14 ₄ are used for this light-shielding. The resin wall 21 separates them from each other. An insulating layer colored black may be applied to the light shielding resin wall 21.

So as to surround the periphery of the LED 12 multiple _{PD14 1 · 14 2 · 14 3} · 14 4 to place around the _{LED12, PD14 1 · 14 2 ·} 14 3 · Effective plurality of light information around the LED 12 can be grasped by the 14 _4, and applied to a photoelectric pulse wave sensor, it is possible improve its operational stability. Moreover, since the number of LEDs used is one, low power consumption operation is possible.

Although illustration is omitted, an operation unit, a display unit, and the like are arranged on the top surface side of the vital sensor module 2 according to the first embodiment so as to be operated/observed by the subject, and contact the human body 18. Optical sensors and various sensors may be arranged on the bottom side.

When the wearing state of the optical sensor 1 and the human body 18 is not good, the main body moves in the X-axis, Y-axis, and Z-axis directions as shown in FIG. Although the contact distance Δ between the human body 18 and the human body 18 fluctuates, the vital sensor module 2 according to the first embodiment maintains the correct wearing state because the wearing state is explicitly displayed to the subject. Measurement can be performed. By making the mounting state explicit, it is possible to prevent measurement in a mounting failure state and always measure in a correct state (correct value). It is possible to clarify the ideal state of wearing to the subject, and the usability is improved.

A schematic bird's-eye view configuration of the vital sensor module 2 according to the first embodiment is represented as shown in FIG.

As shown in FIG. 8, the vital sensor module 2 according to the first embodiment includes a PCB 20, an LED 12 disposed on the surface of the PCB 20, and a PD 14 disposed on the surface of the PCB 20 and spaced apart from the LED 12. _1, 14 _2, 14 _3, 14 _4, on the surface of the PCB 20, LED 12 and PD 14 _1, 14 _2, 14 _3, 14 sensor 16, which is ₄ spaced apart from the arrangement _1, 16 _2, 16 _3, 16 ₄ The light emitted from the LED 12, which is brought into contact with the human body 18 or the body surface of an animal, is reflected by the PD 14 ₁ , 14 ₂ , 14 _3, and 14 ₄ and is received, and the intensity of the reflected light is detected. At the same time, the sensor can clearly indicate information about the contact state with the body surface based on the sensor output value detected by contacting the body surface.

Further, as shown in FIG. 8, a black light-shielding resin wall 21 is arranged on the surface of the PCB 20, and the LED 12 and PDs 14 ₁ , 14 ₂ , 14 ₃ , 14 ₄ , sensor (thermistor) 16 ₁ , The 16 ₂ 16 ₃ 16 ₄ are separated from each other by the light shielding resin wall 21. An insulating layer colored black may be applied to the light shielding resin wall 21.

The vital sensor module 2 according to the first embodiment may detect the wavelength, the attenuation ratio, or the phase difference of the reflected light.

The sensor can determine the wearing state depending on whether the sensor output value is within the threshold range or outside the threshold range.

Further, in the vital sensor module 2 according to the first embodiment, the surface in contact with the body surface may include a flat surface, and the surface in contact with the body surface may include a light receiving surface, a light emitting surface, and a sensor contact surface. It should be noted that the surface in contact with the body surface does not necessarily have to be a flat surface, and may be intentionally a curved surface to fit the arm.

In addition, in the vital sensor module 2 according to the first embodiment, the LED 12 includes a green light emitting diode and can measure a pulse wave.

In addition, in the vital sensor module 2 according to the first embodiment, the LED 12 includes a red light emitting diode or an infrared light emitting diode, and can measure blood oxygen saturation.

Further, as shown in FIG. 8, the sensor includes thermistors 16 ₁ 16 ₂ 16 ₃ 16 ₄ for detecting the temperature of the surface in contact with the body surface when worn, and the thermistors 16 ₁ 16 ₂ 16 ₃ The wearing state may be determined depending on whether the measured value of 16 ₄ is within the threshold range or outside the threshold range, and the information regarding the wearing condition may be made explicit to the subject.

Further, the thermistors 16 ₁ 16 ₂ 16 ₃ 16 ₄ can be applied to the measurement of the temperature of the body surface of the human body 18 or the animal. It is possible to estimate the body temperature from the temperature of the body surface of the human body 18 or the animal.

Further, as shown in FIG. 8, the vital sensor module 2 according to the first embodiment is arranged on the front surface of the PCB 20 (the surface on the side in contact with the human body 18 is referred to as the back surface or the bottom surface). The housing 10 may be provided.

An example of a schematic block configuration inside the housing 10 of the vital sensor module 2 according to the first embodiment is represented as shown in FIG.

Here, in the vital sensor module 2 according to the first embodiment, as shown in FIG. 9, the housing 10 includes a power supply unit 34, a wireless communication unit 32 connected to an antenna 36, a control unit 30, and an operation unit. 35, the display unit 40, or the storage unit 42 can be incorporated.

Further, the vital sensor module 2 according to the first embodiment may include an electronic circuit component arranged on the surface of the substrate 20 as in the configuration shown in FIG. The electronic circuit component may be, for example, an integrated circuit component such as an LED driver or a passive circuit component such as a capacitor, a resistor and an inductor.

Moreover, in the vital sensor module 2 according to the first embodiment, the housing 10 is wearable.

Further, the PCB 20 may be provided with a flexible material having flexibility according to the shape on the body surface of a human body or an animal. That is, the substrate may include a flexible printed circuit board.

(Operating method of vital sensor module)
A flowchart showing the operating method of the vital sensor module 2 according to the first embodiment is expressed as shown in FIG.

The operation method of the vital sensor module 2 according to the first embodiment is, as shown in FIG. 10, a step S1 of turning on the power, a step S2 of starting measurement by the optical sensor 1, and a mounting state being correct. Step S3, which determines whether or not it is determined, and if the mounting state is not correct in Step S3, Step S4 that displays an alert on the display unit (40), and the measurement is reset by receiving the alert display and the measurement by the optical sensor 1. Step S5 for returning to step S2, step S6 for continuing measurement by the optical sensor 1 if the wearing state is correct in step S3, and step S7 for storing the measured data in the storage unit (42). And a step S8 of ending the measurement and a step S9 of turning off the power supply.

Further, in FIG. 10, a flowchart showing a detailed operation method between step S6 and step S7 is expressed as shown in FIG.

First, after step S6 in which measurement by the optical sensor 1 is continued, the process proceeds to step S61 in which it is determined whether or not signal acquisition by another sensor is to be performed. Here, the other sensor is assumed to be, for example, a temperature sensor, a pressure sensor, or the like.

In step S61, in the case of performing signal acquisition by another sensor (YES), the process proceeds to step S62 and a signal by another sensor is acquired.

Next, after performing signal acquisition by another sensor in step S62, it transfers to step S63 and stores the acquired signal information in the memory|storage part (memory) 42.

Next, in step S63, the acquired signal information is stored in the storage unit (memory) 42, and then the process proceeds to step S64 to acquire the pulse wave signal.

Further, in step S61, when the signal acquisition by another sensor is not performed (NO), the process proceeds to step S64 and the pulse wave signal is acquired.

Next, in step S64, after acquiring the pulse wave signal, the process proceeds to step S7, and the acquired pulse wave signal information (data) is stored in the storage unit (memory) 42.

Furthermore, after step S7, the operations of step S61, step S62, step S63, and step S64 may be repeated.

(Relationship between pulse wave signal strength and sample number S)
The vital sensor module according to the first embodiment includes the LED 12 that emits visible light and/or near infrared light and the PD 14 that has sensitivity in the same band, and can provide a pulse wave sensor module.

Further, the vital sensor module according to the first embodiment can form a pulse wave sensor/thermistor/acceleration sensor, etc., as one combined module by mounting sensors such as the thermistor/acceleration sensor, etc. The mounting form is such that it is closely attached to the body surface such as fingertip/wrist/external ear canal (wristwatch/wristband/earphone etc.) and is mounted on the body.

(Target area of signal amplitude)
In the vital sensor module according to the first embodiment, a measurement example of the relationship between the pulse wave signal intensity (au) and the sample number S is represented as shown in FIG. Further, in the vital sensor module according to the first embodiment, another measurement example of the relationship between the pulse wave signal intensity (au) and the sample number S is expressed as shown in FIG.

Here, sampling is performed 200 times per second, for example. Therefore, the number of samples S=1000 (pieces) on the horizontal axis in FIGS. 12 and 13 corresponds to 5 seconds, and the number of samples S=11000 (pieces) corresponds to 55 seconds. Therefore, in the two examples shown in FIGS. 12 and 13, the horizontal axis corresponds to sampling for 50 seconds. In addition, when the sampling frequency is relatively low, for example, 20 Hz, the resolution of the obtained pulse wave decreases, and it becomes difficult to visualize the respiratory rhythm. For this reason, it is desirable that the sampling frequency is in a relatively high frequency range of about 100 Hz to 1 kHz.

Further, in both of the two examples shown in FIGS. 12 and 13, the number of respirations at the time of pulse wave measurement is unified at 13 times/minute.

In the vital sensor module according to the first embodiment, an example of measurement of the respiratory rate by the envelope curve of the relationship between the pulse wave signal intensity (au) and the sample number S in FIG. 12 (sample number S=1000 to 6000 (pieces)) ) Is represented as shown in FIG. Further, in the vital sensor module according to the first embodiment, a measurement example of the number of breaths by the envelope curve of the relationship between the pulse wave signal intensity (au) and the sample number S in FIG. 12 (sample number S=6000 to 11000( 15) is represented as shown in FIG.

Here, the sampling is performed 200 times per second, for example. Therefore, the sample number S=1000 (pieces) on the horizontal axis of FIG. 14 corresponds to 5 seconds, and the sample number S=6000 (pieces) corresponds to 30 seconds. Therefore, in the example shown in FIG. 14, the horizontal axis corresponds to sampling for 25 seconds.

Similarly, the number of samples S=6000 (pieces) on the horizontal axis of FIG. 15 corresponds to 30 seconds, and the number of samples S=11000 (pieces) corresponds to 55 seconds. Therefore, in the example shown in FIG. 15, the horizontal axis corresponds to sampling for 25 seconds.

In the vital sensor module according to the first embodiment, the top and bottom peak values of the waveform of the pulse wave signal intensity (au) are arranged in time series to obtain an envelope curve that reflects the respiratory rhythm. ..

In the vital sensor module according to the first embodiment, as shown in FIGS. 12 to 15, when attention is paid to changes in the pulse wave signal intensity (signal amplitude) in a region lower than the baseline AA line of the pulse wave, respiration It can be seen that the components are appearing and the changes associated with breathing appear.

In the vital sensor module according to the first embodiment, since the signal amplitude of the obtained pulse wave changes with the respiration, the change in the region below the baseline AA line of the signal amplitude is particularly monitored. Therefore, the respiratory rhythm can be detected.

(Change in signal amplitude due to apnea)
In the vital sensor module according to the first embodiment, a measurement example (sample number S=1000 to 8000 (pieces)) of the relationship between the pulse wave signal intensity (au) and the sample number S during apnea is shown in FIG. It is represented as shown in. Further, in the vital sensor module according to the first embodiment, another measurement example of the relationship between the pulse wave signal intensity (au) and the sample number S during apnea (sample number S=1000 to 11000 (pieces)) Is represented as shown in FIG.

Here, the sampling is performed 200 times per second, for example. Therefore, in the two examples shown in FIGS. 16 and 17, the horizontal axis corresponds to sampling for 35 seconds and 50 seconds, respectively.

In both of the two examples shown in FIGS. 16 and 17, the number of breaths at the time of pulse wave measurement is unified to be zero.

In the example shown in FIG. 16, the initial value of the signal amplitude of the pulse wave signal intensity (au) at the time of apnea is 1200, while the signal amplitude of the pulse wave signal intensity (au) is 35 seconds later. , About 300.

Similarly, in the example shown in FIG. 17, the initial value of the signal amplitude of the pulse wave signal intensity (au) at the time of apnea is 1000, whereas after 50 seconds, the pulse wave signal intensity (au) of the pulse wave signal intensity (au) is changed. The signal amplitude has been reduced to about 600.

By stopping breathing, oxygenated hemoglobin (HbO ₂ ) in blood is decreased, and blood oxygen saturation is decreased. Therefore, the signal amplitude of the pulse wave decreases even when the same amount of blood is being propagated.

Therefore, in the vital sensor module according to the first embodiment, the presence or absence of respiration can be determined by measuring the decreasing tendency of the signal amplitude of the pulse wave.

Generally, if apnea of 10 seconds or more is observed 30 times or more in 7 hours, or if the number of apnea or hypopnea is 5 or more in 1 hour, it is determined to be apnea. To be done.

(Operating method of vital sensor module: Flowchart example 1)
The flowchart example 1 which shows the operating method of the vital sensor module which concerns on 1st Embodiment is represented as shown in FIG. An explanatory diagram of the pulse wave signal waveform corresponding to the operation method shown in FIG. 18 is expressed as shown in FIG.

As shown in FIG. 19, the bottom n-th time of the pulse wave signal waveform is defined by T _n , and the bottom n-th signal strength is defined by B _n .

Hereinafter, an operation flowchart example 1 of the vital sensor module according to the first embodiment will be described.
(A) First, in step S11, a pulse wave is acquired by an optical sensor.
(B) Next, in step S12, the acquired analog signal of the pulse wave is converted into a digital signal via the A/D converter.
(C) Next, in step S13, the bottom of the pulse wave is detected and a time stamp as time information is added. The obtained data is (T _n , B _n ).
(D) Next, in step S14, the bottom of the interval _{D n (= T n -T n} -1) is calculated, and compared to before and after the time interval _{(D n-1, D n} + 1), For example, when it is about 50% or about 200% or more, it is excluded as an error value. The values (T _c , B _c ) supplemented from the preceding and following time intervals are assigned to the data excluded as the error value. Here, as the complemented value, a method of taking a simple average of preceding and following data, a method of taking a weighted average, or the like can be adopted.
(e) After the above processing, in step S15, the moving average processing is appropriately performed on the data group (B ₀ , B ₁ ,..., B _n ,... ). The data group after the moving average processing is (b ₀ , b ₁ ,..., B _n ,...).
(F) Next, in step S16, an envelope is obtained by connecting the respective data (T _n , b _n ) that have been subjected to the moving average processing, and a peak or bottom value per unit time is obtained for the obtained envelope. By obtaining, the information of the respiratory rate is obtained.

If conversation or forced breathing is detected by the microphone during the above operation, the fact is notified to the system side (flag notification).

Since the information on the respiratory rate obtained during this period may not be correctly detected by conversation or the like, the system side may determine whether to utilize the information.

(Operating method of vital sensor module: Flowchart example 2)
A flowchart example 2 showing another operating method of the vital sensor module according to the first embodiment is expressed as shown in FIG. An explanatory diagram of the pulse wave signal waveform corresponding to the operation method shown in FIG. 20 is expressed as shown in FIG.

As shown in FIG. 21, the peak n-th time of the pulse wave signal waveform is t _n , the peak n-th signal strength is P _n , the bottom n-th time is T _n , and the bottom n-th signal strength is B _n . It is defined.

Hereinafter, an operation flowchart example 2 of the vital sensor module according to the first embodiment will be described.
(A) First, in step S21, a pulse wave is acquired by an optical sensor.
(B) Next, in step S22, the acquired analog signal of the pulse wave is converted into a digital signal via the A/D converter.
(C) Next, in step S23, the peak and bottom of the pulse wave are detected, and a time stamp as time information is added. The obtained peak data is (t _n , P _n ) and the obtained bottom data is (T _n , B _n ).
(D) Next, in step S24, to calculate the peak signal strength and the bottom signal intensity difference (P _n -B _n) or _{(P n -B n-1)} , and the signal amplitude [Delta] H _n.
(E) Next, in step S25, the signal amplitude ΔH is calculated in accordance with the passage of time, and the amount of change in the signal amplitude ΔH is monitored.
(F) Next, in step S26, when the signal amplitude ΔH continuously decreases for a certain period of time (for example, 15 seconds, 30 seconds, etc.), it is determined that proper breathing is not maintained, and the system side Notify to that effect.

In the vital sensor module according to the first embodiment, a measurement example of the relationship between the pulse wave signal intensity (a.u.) and the number of samples S during the operation of FIG. 20 is expressed as shown in FIG. In the example shown in FIG. 22, the signal amplitude is continuously decreased from ΔH=1200 to ΔH=300 in 35 seconds.

A pulse wave signal waveform example in the vital sensor module according to the comparative example, which is a typical waveform example including the ejection wave P1 and the reflected wave P2, is shown in FIG. An example of a waveform having a notch or an inflection point (pseudo P1) is shown in FIG. 23(b), and an example of a waveform having a systolic apex deformation/amplitude change of a reflected wave is shown in FIG. 23(c). An example of the waveform having the unnatural inflection line of the descending leg is represented as shown in FIG.

FIG. 24A is a pattern example of a pulse wave signal waveform that requires attention in the vital sensor module according to the comparative example, and a systolic variation example (notch type) is represented as shown in FIG. ) Is represented as shown in FIG. 24( b ), and the diastolic variation (ripple type) is represented as shown in FIG. 24( c ).

Due to the pressing pressure between the measuring instrument and the skin, distortion is generated at each peak of the pulse wave as shown in FIGS. Further, each peak of the pulse wave is affected by the pressing force between the measuring instrument and the skin, and a plurality of peaks including false peaks appear. Therefore, when the upper envelope is adopted, the detection accuracy is lowered due to the mixing of the false peak, but in the vital sensor module according to the first embodiment, pay attention to the lower envelope rather than the upper envelope. Therefore, the respiratory rhythm can be detected.

Further, in the vital sensor module according to the first embodiment, the data calculation load on the MCU is small, and it is possible to achieve low power consumption and low cost.

In addition, in the vital sensor module according to the first embodiment, since the amplitude change associated with the occurrence of bradycardia is detected using the lower envelope, the lead time until detection is short, and body movement noise and Is easy to distinguish.

Further, in the vital sensor module according to the first embodiment, the detection accuracy can be improved by combining the information on the body surface temperature/speech and the presence or absence of forced respiration (sampling frequency: low).

Further, in the vital sensor module according to the first embodiment, depending on the measurement state, by referring to the sensor output information (body surface temperature/presence/absence of body movement/presence/absence of conversation, etc.) that is acquired at the same time, The detection accuracy of the respiratory rhythm can be improved.

In addition, in the vital sensor module according to the first embodiment, it is possible to monitor the respiratory rhythm of the wearer by a simple method without a large wearing load.

Further, by using the vital sensor module according to the first embodiment, it is not necessary to visit a specialized institution or the like, and it is possible to monitor in an environment close to daily life.

Further, by using the vital sensor module according to the first embodiment, it becomes possible to visualize relaxation rhythm by helping to visualize the respiratory rhythm.

As described above, according to the first embodiment, the respiratory component such as the respiratory rhythm, the respiratory rate, and the presence/absence of breathing is reduced by reducing the burden of the wearing state of the subject and focusing on the signal amplitude change of the pulse wave. It is also possible to monitor the wearer's condition by acquiring information such as pulse rate, blood oxygen saturation, and whether or not there is body movement. Vital sensor module and its operation A method can be provided.

[Second Embodiment]
In the vital sensor module 2 according to the second embodiment, a schematic plan configuration viewed from the side in contact with the human body is shown in FIG.

In the vital sensor module 2 according to the second embodiment, the sensor includes a pressure sensor that detects the contact pressure with the surface that comes into contact with the body surface when worn. That is, a pressure sensor that detects a contact pressure (pressing pressure) may be provided on a surface (area) that comes into contact with the body (skin) when worn, so that the information regarding the wearing condition may be made explicit to the subject.

As shown in FIG. 25, the vital sensor module 2 according to the second embodiment includes a PCB 20, an LED 12 arranged on the surface of the PCB 20, and a PD 14 ₁ arranged on the surface of the PCB 20 spaced apart from the LED 12. 14 ₂ ·14 ₃ ·14 ₄ and a pressure sensor 22 ₁ ·22 ₂ ·22 ₃ ·22 ₄ arranged on the surface of the PCB 20 apart from the LED 12 and PD 14 ₁ ·14· ₂ ·14 ₃ ·14 _4. The light emitted from the LED 12 is brought into contact with the human body 18 or the body surface of an animal and the reflected light returning from the inside of the living body is received by the PD 14 ₁ , 14 ₂ , 14 ₃ , 14 ₄ and the intensity of the reflected light is detected. At the same time, the pressure sensors 22 ₁ , 22 ₂ , 22 _3, and 22 ₄ can clearly indicate information regarding the contact state with the body surface based on the sensor output value detected by contacting the body surface.

Further, as shown in FIG. 25, a black light-shielding resin wall 21 is arranged on the surface of the PCB 20, and the LED 12 and the PDs 14 ₁ , 14 ₂ , 14 ₃ , 14 ₄ , pressure sensors 22 ₁ , 22 ₂ are arranged. · 22 ₃ · 22 _4, by the light shielding resin walls 21 are spaced apart from each other. An insulating layer colored black may be applied to the light shielding resin wall 21.

The vital sensor module 2 according to the second embodiment may detect the wavelength, the attenuation ratio, or the phase difference of the reflected light.

The sensor can determine the wearing state depending on whether the sensor output value is within the threshold range or outside the threshold range. Other configurations and operating methods are similar to those of the first embodiment.

According to the second embodiment, similar to the first embodiment, the burden on the wearing state of the subject is reduced and the signal amplitude change of the pulse wave is focused to determine the respiratory rhythm, the respiratory rate, and the presence/absence of respiration. It is also possible to extract the respiratory components such as, and it is also possible to monitor the wearer's condition by also acquiring information such as pulse rate, blood oxygen saturation, and the presence or absence of body movement. A module and its operating method can be provided.

[Third Embodiment]
In the vital sensor module 2 according to the third embodiment, a schematic plan configuration viewed from the side in contact with the human body is shown in FIG.

In the vital sensor module 2 according to the third embodiment, as shown in FIG. 26, the sensor detects the temperature of the surface which is in contact with the body surface when the thermistor 16 ₁ , 16 ₂ , 16 ₃ , 16 _{4 is} mounted. And pressure sensors 22 ₁ , 22 ₂ , 22 ₃ , 22 ₄ for detecting the contact pressure with the surface that comes into contact with the body surface when worn.

The vital sensor module 2 according to the third embodiment is attached to the human body 18 via the strap 50.

As shown in FIG. 26, the schematic planar configuration of the photosensor portion arranged on the bottom surface side of the vital sensor module 2 according to the third embodiment in contact with the human body 18 is such that the LED 12 is arranged at the center and the periphery of the LED 12 is arranged. A plurality of PDs 14 ₁ , 14 ₂ , 14 ₃ , 14 ₄ are arranged so as to surround the. In the example of FIG. 26, four PDs are arranged.

So as to surround the periphery of the LED 12 multiple _{PD14 1 · 14 2 · 14 3} · 14 4 to place around the _{LED12, PD14 1 · 14 2 ·} 14 3 · Effective plurality of light information around the LED 12 can be grasped by the 14 _4, and applied to a photoelectric pulse wave sensor, it is possible improve its operational stability. Moreover, since the number of LEDs used is one, low power consumption operation is possible.

Although illustration is omitted, the vital sensor module 2 according to the third embodiment is provided with an operation unit, a display unit, and the like on the top surface side so that the subject can operate and observe the human body 18. Optical sensors, thermistors 16 ₁ , 16 ₂ , 16 ₃ , 16 ₄ , pressure sensors 22 ₁ , 22 ₂ , 22 ₃ , 22 _4, etc. are arranged on the bottom surface side. The optical sensor, thermistor 16 ₁ , 16 ₂ , 16 ₃ , 16 ₄ and the pressure sensor 22 ₁ , 22 ₂ , 22 ₃ , 22 ₄ are arranged on the same PCB arranged on the housing 10. Is also good. Alternatively, they may be arranged on different substrates.

Depending on whether the measurement value of the thermistor 16 ₁ 16 ₂ 16 ₃ 16 ₄ is within the threshold range or outside the threshold range, the wearing state is determined and the information regarding the wearing condition is made explicit to the subject. Is also good.

Further, the thermistors 16 ₁ 16 ₂ 16 ₃ 16 ₄ can be applied to the measurement of the temperature of the body surface of the human body 18 or the animal.

In addition, the wearing state is determined based on whether the measured values of the pressure sensors 22 ₁ , 22 ₂ , 22 ₃ , 22 ₄ are within the threshold range or outside the threshold range, and the information regarding the wearing condition is displayed to the subject. It may be appropriate. Other configurations and operating methods are the same as those in the first embodiment or the second embodiment.

According to the third embodiment, as in the first embodiment, the burden on the wearing condition of the subject is reduced and the change in the signal amplitude of the pulse wave is focused on to determine the respiratory rhythm, the respiratory rate, and the presence/absence of respiration. It is also possible to extract the respiratory component such as, and it is also possible to monitor the condition of the wearer by also acquiring information such as pulse rate, blood oxygen saturation, presence or absence of body movement, etc. A module and its operating method can be provided.

(Fourth Embodiment)
In the vital sensor module 2 according to the fourth embodiment, a schematic plan configuration viewed from the side in contact with the human body is shown in FIG.

In the vital sensor module 2 according to the fourth embodiment, as shown in FIG. 27, the sensor detects the temperature of the surface in contact with the body surface when the thermistor 16 ₁ , 16 ₂ , 16 ₃ , 16 _{4 is} mounted. And pressure sensors 22 ₁ , 22 ₂ , 22 ₃ , 22 ₄ for detecting the contact pressure with the surface that comes into contact with the body surface when worn.

The vital sensor module 2 according to the fourth embodiment is attached to the human body 18 via the strap 50.

As shown in FIG. 27, the schematic planar configuration of the optical sensor portion arranged on the bottom surface side of the vital sensor module 2 according to the fourth embodiment in contact with the human body 18 is such that the PD 14 is arranged at the center and the periphery of the PD 14 is arranged. A plurality of LEDs 12 ₁ , 12 ₂ , 12 ₃ , 12 ₄ are arranged so as to surround the. In the example of FIG. 27, four LEDs are arranged.

By arranging a plurality of LEDs 12 ₁ 12 ₂ 12 ₃ 12 ₄ so as to surround the periphery of the PD 14, it is possible to compensate for the insufficient light amount of the PD 14 and to irradiate the PD 14 with the same amount of light from the surroundings. it can. Therefore, it can be applied to a photoelectric pulse wave sensor or the like to improve its operation stability.

Although illustration is omitted, the vital sensor module 2 according to the fourth embodiment is provided with an operation unit, a display unit, and the like on the top surface side so that the subject can operate and observe the human body 18. Optical sensors, thermistors 16 ₁ , 16 ₂ , 16 ₃ , 16 ₄ , pressure sensors 22 ₁ , 22 ₂ , 22 ₃ , 22 _4, etc. are arranged on the bottom side. The optical sensor, thermistor 16 ₁ , 16 ₂ , 16 ₃ , 16 ₄ and the pressure sensor 22 ₁ , 22 ₂ , 22 ₃ , 22 ₄ are arranged on the same PCB arranged on the housing 10. Is also good. Alternatively, they may be arranged on different substrates.

Depending on whether the measurement value of the thermistor 16 ₁ 16 ₂ 16 ₃ 16 ₄ is within the threshold range or outside the threshold range, the wearing state is determined and the information regarding the wearing condition is made explicit to the subject. Is also good.

Further, the thermistors 16 ₁ 16 ₂ 16 ₃ 16 ₄ can be applied to the measurement of the temperature of the body surface of the human body 18 or the animal.

In addition, the wearing state is determined based on whether the measured values of the pressure sensors 22 ₁ , 22 ₂ , 22 ₃ , 22 ₄ are within the threshold range or outside the threshold range, and information regarding the wearing condition is clearly shown to the subject. It may be appropriate. Other configurations and operating methods are similar to those of the first to third embodiments.

According to the fourth embodiment, as in the first embodiment, the burden on the subject due to the wearing state is reduced and the change in the signal amplitude of the pulse wave is focused on to determine the respiratory rhythm, the respiratory rate, and the presence/absence of respiration. It is also possible to extract the respiratory components such as, and it is also possible to monitor the wearer's condition by also acquiring information such as pulse rate, blood oxygen saturation, and the presence or absence of body movement. A module and its operating method can be provided.

(Fifth Embodiment)
A bird's-eye view of the optical sensor portion 2A of the vital sensor module 2 according to the fifth embodiment is shown in FIG. 28(a), and an explanatory view of FIG. 28(a) is shown in FIG. 28(b). Is represented as

A bird's-eye view of the vital sensor module 2 according to the fifth embodiment is shown in FIG. 29(a), and an explanatory view of FIG. 29(a) is shown in FIG. 29(b). ..

28 and 29, the optical sensor 1 is projected from the surface of the module housing 10 by about 1 mm to 2 mm. A power switch (SW) 102 is arranged on the side surface of the module housing 10. Further, the power can be supplied from the outside via the micro USB terminal 110, for example. In addition, as a power source, a solar cell, a dye-sensitized solar cell, an organic thin film solar cell, or the like may be incorporated to make it wireless. Further, similarly to the vital sensor module 2 according to the first embodiment, a configuration capable of performing wireless communication with an external PC/mobile terminal may be adopted.

In FIG. 29, for example, the length L is about 35 mm, the width W is about 25 mm, and the thickness D is about 13 mm. It should be noted that the above dimensions are an example, and as described in the mounting example of the vital sensor module according to the embodiment, an appropriate size according to the mounting state on the forearm, the index finger, the ear canal entrance, and other human body parts. May be miniaturized.

In order to determine the mounting state, various sensors can be arranged in the sensor arrangement portions SR1 and SR2 around the optical sensor 1 on the surface of the module housing 10. A thermistor, an inter-electrode resistance sensor, a pressure sensor, etc. can be arranged in each sensor.

It is desirable to arrange two or more measurement points in order to measure the temperature, the pressure, the resistance value and the like and to stably determine the mounting state. That is, if the thermistor is arranged in plural, it is preferable to compare the data of plural measuring points. In the case of an inter-electrode resistance sensor, it is advisable to arrange a plurality of electrodes, measure the resistance value between the plurality of electrodes, and compare the data. If it is a pressure sensor, it is advisable to arrange a plurality of pressure sensors and compare data at a plurality of measurement points.

The measuring unit of the vital sensor module according to the fifth embodiment is not limited to the timepiece type because it is assumed to be other than the wrist and the forearm. As described in the mounting example of the vital sensor module according to the embodiment, the vital sensor module may be mounted on the index finger/external ear canal entrance or another human body part.

Further, an operation unit, a display unit, and the like are arranged on the bottom surface side (in the usage state, the top surface side) of the vital sensor module 2 according to the fifth embodiment so that the subject can operate/observe. Then, the optical sensor 1, various sensors, and the like are arranged on the surface side in contact with the human body 18 (which is the surface in contact with the human body in the use state).

(Schematic block configuration of vital sensor module)
A schematic block configuration of the vital sensor module 2 according to the fifth embodiment is represented as shown in FIG.

As shown in FIG. 30, the vital sensor module 2 according to the fifth embodiment includes a power supply unit 34, a control unit 30 connected to the power supply unit 34, and an optical sensor for detecting optical information of an external living body 18. 1, a sensor (temperature sensor 38, various sensors 43) that detects contact information with the living body 18, a display unit 40 that displays mounting information with the living body 18, and an optical sensor 1 and the sensors (38 and 43). And a storage unit 42 that stores the stored data.

The vital sensor module 2 according to the fifth embodiment may include a temperature sensor 38 that detects the temperature of the living body 18, as shown in FIG.

As shown in FIG. 30, the vital sensor module 2 according to the fifth embodiment may include a pressure sensor as various sensors 43 that detect contact information with the living body 18.

As shown in FIG. 30, the vital sensor module 2 according to the fifth embodiment includes a wireless communication unit 32 and an antenna 36 for wirelessly communicating mounting information with the living body 18, and an external PC/portable terminal 4 is provided. It is possible to carry out wireless communication with.

As shown in FIG. 30, the vital sensor module 2 according to the fifth embodiment has a speaker 47 that clearly indicates mounting information on the living body 18, an external interface 33 that can be connected to an external device, and an operation that executes an operation. The unit 35 and the microphone 37 for inputting voice information may be provided. Here, the external device connected to the external interface (I/F) 33 may include a charging device or the like. Here, as the charging method, for example, a method of supplying power from the outside through the micro USB terminal 110 or a method of wirelessly feeding power from the outside through a micro coil may be applied. Further, a solar cell, a dye-sensitized solar cell, an organic thin-film solar cell, or the like may be built in to make it compact and wireless.

Other configurations and operating methods are the same as those in the first to fourth embodiments.

(Circuit block configuration of vital sensor module)
The circuit block configuration of the vital sensor module according to the fifth embodiment is represented as shown in FIG.

The LED/PD in the optical sensor 1 is connected to the MCU 30 via the LED driver 1D/analog front end (AFE) 1A.

The thermistor 38 is connected to the MCU 30 via an amplifier and an A/D converter 38A.

The microphone 37 is connected to the MCU 30 via an amplifier and an A/D converter 37A.

Further, the MCU 30 may be connected to, for example, an acceleration sensor 43 as various sensors and may be capable of detecting body movement.

Further, the MCU 30 may be connected to the wireless communication unit (RF) 32.

Further, the MCU 30 may be connected to the speaker 47 via the D/A converter and the amplifier 47A.

Further, the MCU 30 may be connected to the display 40 and the memory 42.

According to the fifth embodiment, similar to the first embodiment, the burden on the subject due to the wearing state is reduced and the change in the signal amplitude of the pulse wave is focused on, thereby determining the respiratory rhythm, the respiratory rate, and the presence/absence of respiration. It is also possible to extract the respiratory components such as, and it is also possible to monitor the wearer's condition by also acquiring information such as pulse rate, blood oxygen saturation, and the presence or absence of body movement. A module and its operating method can be provided.

(Operating method of vital sensor module: Optical sensor calibration)
A flowchart showing the operating method of the vital sensor module according to the first to fifth embodiments is expressed as shown in FIG.

As shown in FIG. 32, the operating method of the vital sensor module according to the first to fifth embodiments includes a mounting state determination step S31, and a step S32 of determining whether or not the measured value of the sensor is within a threshold range. If the measured value of the sensor is not within the threshold value range in the above-mentioned determination step S32, an alert is displayed and the measurement value of the sensor is returned to the mounting state determination step in step S33 Is within the threshold range, step S34 for performing optical sensor calibration, step S35 for measuring with the optical sensor, step S36 for determining whether or not the measurement by the optical sensor is finished, and If the measurement has not been completed, the process returns to step S35 for measuring with the optical sensor, and if the measurement with the optical sensor has been completed, the process ends.

Here, a thermistor, a pressure sensor, an interelectrode resistance sensor, or the like can be applied to the sensor. For example, when a plurality of thermistors are arranged, the output value of each thermistor is monitored, and if even one is out of the threshold range, the determination result can be NO in step S32.

As the alert display in step S33, for example, blinking display by LED or display display can be applied.

“Optical sensor calibration” is defined as follows.

Since the pulse wave detection sensitivity varies depending on the person and the measurement unit, in order to obtain a substantially constant output (amplitude of the pulse wave), it is necessary to change the LED light amount according to the person and the measurement unit. .. Therefore, the output (amplitude of the pulse wave) when the LED light amount is changed from a relatively low state to a relatively high state is monitored, and the initial setting for determining the optimum LED light amount for the subject is set to the This is called sensor calibration.

A flowchart showing another operation method of the vital sensor module according to the first to fifth embodiments is expressed as shown in FIG.

Another operation method of the vital sensor module according to the first to fifth embodiments is, as shown in FIG. 33, a mounting state determining step S41 and a step of determining whether or not the measured value of the thermistor is within a threshold range. If the measured value of the thermistor is not within the threshold value range in S42 and the above-described determination step S42, an alert is displayed and the process returns to the mounting state determination step S43, and in the determination step S42, the thermistor If the measured value is within the threshold range, step S44 of performing optical sensor calibration, step S45 of measuring the pulse wave with the optical sensor, step S46 of measuring the temperature with the thermistor, and measuring the temperature with the thermistor. Step S47 of determining whether or not the result is continuously less than the threshold value for a predetermined time, and if the temperature measurement result by the thermistor is continuously less than the threshold value for the predetermined time period, an alert is displayed and the mounting state is The step S43 of returning to the determination step S41, and step S48 of determining whether or not the pulse wave measurement by the optical sensor is finished when the temperature measurement result by the thermistor is not less than the threshold value continuously for a predetermined time, If the pulse wave measurement by the sensor is not completed, the process returns to step S45 of measuring the pulse wave by the optical sensor, and if the pulse wave measurement by the optical sensor is completed, the process is ended.

As the alert display in step S43, for example, blinking display by LED or display display can be applied.

(Examples of various pressure sensors)
-Button type pressure sensor-
As the pressure sensor 22 applicable to the vital sensor module 2 according to the embodiment, a button type pressure sensor can be applied. In the vital sensor module 2 according to the embodiment to which the button type pressure sensor is applied, the mounting state can be determined depending on whether the output value of the button type pressure sensor is within the threshold range or outside the threshold range.

-Air blow type pressure sensor-
As the pressure sensor 22 applicable to the vital sensor module 2 according to the embodiment, an air blowing type pressure sensor can be applied. In the vital sensor module 2 according to the embodiment to which the air blowing type pressure sensor is applied, the mounting state can be determined depending on whether the output value of the air blowing type pressure sensor is within the threshold range or outside the threshold range. it can. For example, depending on the air pressure of the air blowing port, it may be determined that the mounting state is poor in the pressure released state, and that the mounting state is good in the pressure applied state. Further, the contact pressure may be derived by detecting the air resistance at the air outlet that blows out the air.

-Film pressure sensor-
As the pressure sensor 22 applicable to the vital sensor module 2 according to the embodiment, it is possible to apply a film pressure sensor. In the vital sensor module 2 according to the embodiment to which the film pressure sensor is applied, the mounting state can be determined depending on whether the output value of the film pressure sensor is within the threshold range or outside the threshold range. As the film-like pressure sensor, for example, a film-shaped piezo film pressure sensor can be applied, and processing such as coloring of a pressed region may be performed.

-O-ring resistance film type pressure sensor-
As the pressure sensor 22 applicable to the vital sensor module 2 according to the embodiment, an O-ring resistance film type pressure sensor can be applied. An O-ring resistance film type pressure sensor applicable to the vital sensor module 2 according to the embodiment includes a glass substrate, a first transparent electrode layer arranged on the glass substrate, and a first transparent electrode layer arranged on the first transparent electrode layer. A dot spacer, a second transparent electrode layer disposed on the first transparent electrode layer via the dot spacer and a space, and an insulating layer disposed on the second transparent electrode layer. The insulating layer can be formed of, for example, polyethylene terephthalate (PET).

The O-ring resistance film type pressure sensor applies a resistance film type touch panel, and when pressure is applied to the insulating layer, the insulating layer and the second transparent electrode layer are pushed down, and the first and second transparent electrode layers come into contact with each other. , The contact point coordinates can be detected.

-O-ring pressure sensor-
Further, as the pressure sensor 22 applicable to the vital sensor module 2 according to the embodiment, as the O-ring-shaped pressure sensor, an O-ring-shaped tube in which a liquid/gas/laser light source is enclosed is used. The contact pressure may be derived by detecting the current flow and the intensity of laser light.

(Example of inter-electrode resistance sensor)
The contact resistance between electrodes is represented by a parallel circuit of the resistance R _S of the skin portion and the resistance R _W of the surface portion in the contact state with the human body 18, and is usually about 2 kΩ to 5 kΩ. On the other hand, in the non-contact state with the human body 18, it is about several MΩ.

The vital sensor module 2 according to the embodiment may include an inter-electrode resistance sensor that comes into contact with the body surface when worn.

The optical sensor, the thermistor, and the pressure sensor may be arranged on the same PCB arranged on the housing 10. Alternatively, they may be arranged on different substrates.

As in the third embodiment or the fourth embodiment, a thermistor, a pressure sensor, etc. may be provided and used together with these sensors.

The vital sensor module 2 according to the embodiment is attached to the human body 18 via the strap 50.

Further, a black light-shielding resin wall is arranged on the surface of the PCB 20, and the LED and the PD/electrode resistance sensor are separated from each other by this light-shielding resin wall. An insulating layer colored black may be applied to the light shielding resin wall.

The wearing state may be determined depending on whether the measured value of the inter-electrode resistance sensor is within the threshold range or outside the threshold range, and the information regarding the wearing condition may be made explicit to the subject.

In the vital sensor module 2 according to the embodiment, the mounting state can be determined depending on whether the output value of the inter-electrode resistance sensor is within the threshold range or outside the threshold range.

For example, the contact resistance between electrodes is usually about 2 kΩ to 5 kΩ in the contact state with the human body, so if it is within this range, it is determined to be within the threshold range, and in the non-contact state with the human body, about several MΩ. Since it is a degree, if it is within this range, it can be determined that it is outside the threshold range.

The vital sensor module of the present embodiment is a sleep breathing monitor tool, a rehabilitation monitor tool for a medical patient (determining whether or not overload rehabilitation is performed based on the breathing condition), a relaxation tool (managing the respiratory rate. It can be applied to medical measuring devices such as relaxation monitor (abdominal respiration), respiration monitor, activity meter, heart rate monitor.

As described above, according to the present embodiment, the respiratory component such as the respiratory rhythm, the respiratory rate, and the presence/absence of breathing is extracted by reducing the burden of the wearing state of the subject and focusing on the signal amplitude change of the pulse wave. It is also possible to monitor the condition of the wearer by also acquiring information such as pulse rate, blood oxygen saturation, presence or absence of body movement, and a method of operating the same. Can be provided.

[Other Embodiments]
As described above, the description has been given according to the present embodiment, but it should not be understood that the discussion and drawings forming a part of this disclosure are exemplifications and limit the present embodiment. From this disclosure, various alternative embodiments, examples and operational techniques will be apparent to those skilled in the art.

As described above, the present embodiment includes various embodiments not described here.

The vital sensor module according to the present embodiment can be applied to medical measurement devices such as a rehabilitation monitor tool after illness treatment, a sleep biological monitor tool, an activity meter, and a heart rate meter.

DESCRIPTION OF SYMBOLS 1... Optical sensor 2, 2F, 2E... Vital sensor module 4... PC/mobile terminal 8A... Memory 8B... Control integrated circuit 8C... Capacitor 8R... Resistor element 9... Battery 10... Module housing 12, 12 ₁ , 12 ₂ , 12 ₃ , 12 ₄ ... Light emitting element (LED)
14, 14 ₁ , 14 ₂ , 14 ₃ , 14 ₄ ... Light receiving element (PD)
16, 16 ₁ , 16 ₂ , 16 ₃ , 16 ₄ ... Thermistor 18... Human body (living body) (forearm)
18F... Index finger 20, 20A, 20B... Printed circuit board (PCB, board)
21... Light-shielding resin wall (insulating layer)
21B: Columnar resin wall (insulating wall)
22, 22 ₁ , 22 ₂ , 22 ₃ , 22 ₄ ... Pressure sensor 30... Control unit (MCU)
32... Wireless communication unit (RF)
33... External interface (I/F)
34... Power supply unit 35... Operation unit 36... Antenna 37... Microphone 37A, 38A... Amplifier and A/D converter 38... Temperature sensor (thermistor)
40... Display (display)
42... Storage unit (memory)
43... Various sensors (acceleration sensor)
47... Speaker 47A... D/A converter and amplifier 50, 50F... Strap 100... Vital sensor module 102... Power switch (SW)
110... Micro USB terminal (receptacle)
SR ₁ , SR ₂ ... Sensor placement part

Claims (16)

Board,
A light emitting element disposed on a surface of the substrate, which is a surface on the side in contact with the human body, so as to overlap the center of the substrate in a first direction view perpendicular to the substrate;
A light-receiving element disposed on the surface so as to surround the light-emitting element and spaced apart from the light-emitting element ;
A sensor disposed apart from the light emitting element and the light receiving element on the surface ,
In contact with the body surface of the living body, the light emitted from the light emitting element receives the reflected light returning from the inside of the living body by the light receiving element, and detects the pulse wave signal intensity based on the intensity of the reflected light, and By arranging the peak values of the top and bottom of the waveform of the pulse wave signal strength in time series respectively, an envelope curve reflecting the respiratory rhythm can be obtained ,
The sensor includes a pressure sensor that detects a contact pressure with a surface in contact with the body surface when worn,
The pressure sensor includes a plurality of air blowing type pressure sensors , characterized in that the mounting state is determined by whether the output values of the plurality of air blowing type pressure sensors are within a threshold range or outside a threshold range. Vital sensor module. Board,
A light emitting element disposed on a surface of the substrate, which is a surface on the side in contact with the human body, so as to overlap the center of the substrate in a first direction view perpendicular to the substrate;
A light-receiving element disposed on the surface so as to surround the light-emitting element and spaced apart from the light-emitting element;
A sensor disposed on the surface and spaced apart from the light emitting element and the light receiving element;
Equipped with
Contact with the body surface of the living body, the light emitted from the light emitting element is received by the light receiving element reflected light returning from the inside of the living body, while detecting the pulse wave signal intensity based on the intensity of the reflected light, By arranging the peak values of the top and bottom of the waveform of the pulse wave signal strength in time series respectively, an envelope curve reflecting the respiratory rhythm can be obtained,
The sensor includes a pressure sensor that detects a contact pressure with a surface in contact with the body surface when worn,
The pressure sensor comprises a film-shaped pressure sensor, the output value of the film-shaped pressure sensor is within a threshold range or is outside the threshold range to determine the mounting state,
The vital sensor module, wherein the film-shaped pressure sensor includes a piezo film and is capable of developing a color in a pressed region. Board,
A light emitting element disposed on a surface of the substrate, which is a surface on the side in contact with the human body, so as to overlap with the center of the substrate in a first direction view perpendicular to the substrate;
On the surface, a light receiving element that is arranged apart from the light emitting element so as to surround the light emitting element,
A sensor disposed on the surface and spaced apart from the light emitting element and the light receiving element;
Equipped with
In contact with the body surface of the living body, the light emitted from the light emitting element receives the reflected light returning from the inside of the living body by the light receiving element, and detects the pulse wave signal intensity based on the intensity of the reflected light, and By arranging the peak values of the top and bottom of the waveform of the pulse wave signal strength in time series respectively, an envelope curve reflecting the respiratory rhythm can be obtained,
The sensor includes a pressure sensor that detects a contact pressure with a surface in contact with the body surface when worn,
The pressure sensor includes a plurality of button type pressure sensors, and the vital condition is characterized in that the mounting state is determined depending on whether the output values of the plurality of button type pressure sensors are within a threshold range or outside a threshold range. Sensor module. The vital sensor module according to any one of claims 1 to 3, wherein the number of breaths can be measured by an envelope curve of the relationship between the pulse wave signal intensity and the number of samples within a predetermined time. The respiratory rhythm can be detected by monitoring a change in signal amplitude in a region below a predetermined baseline of the pulse wave signal intensity, and the vital according to any one of claims 1 to 4, wherein Sensor module. The vital sensor according to any one of claims 1 to 5, wherein the presence or absence of respiration can be determined by measuring a decreasing tendency of the signal amplitude of the pulse wave signal intensity. module. 7. The sensor according to claim 1, wherein the sensor is capable of clearly indicating information regarding a contact state with the body surface based on a sensor output value detected by contacting the body surface. Vital sensor module. The vital sensor module according to claim 7, wherein the sensor determines a wearing state by whether the sensor output value is within a threshold range or outside the threshold range. The sensor includes a thermistor that detects the temperature of the surface in contact with the body surface when worn, and determines the wearing state by whether the measured value of the thermistor is within a threshold range or outside the threshold range. The vital sensor module according to any one of claims 1 to 7 , which is characterized. The vital sensor module according to claim 9, wherein the thermistor is also applicable to measurement of the temperature of the body surface of the living body. 11. The vital sensor module according to claim 1, wherein the substrate includes a flexible material having flexibility. The vital sensor module according to claim 11, wherein the substrate comprises a flexible printed circuit board. 13. The vital sensor module according to claim 1, wherein the light emitting element includes a light emitting diode. 13. The vital sensor module according to claim 1, wherein the light emitting element includes a red light emitting diode and an infrared light emitting diode, and is capable of measuring blood oxygen saturation. The vital sensor module according to claim 1, wherein the vital sensor module can be mounted on a forearm, a finger, or an ear canal of a human body. 16. The vital sensor module according to claim 1, wherein the vital sensor module is capable of wireless communication with an external personal computer or a mobile terminal.