JP5203971B2 - Chemical injection device - Google Patents

Description

  The present invention relates to a chemical liquid injector that is used together with a medical fluoroscopic imaging apparatus and injects a chemical liquid into a subject to be imaged.

  Currently, fluoroscopic imaging devices for medical use include X-ray CT (Computed Tomography) scanners, MRI (Magnetic Resonance Imaging) devices, PET (Positron Emission Tomography) devices, ultrasound diagnostic devices, CT angiography devices, MRA (MRA) MRA Devices and the like are known.

  When using a device as described above, it is often performed to inject a medical solution such as a contrast medium, a radioactive substance, and physiological saline into a subject in order to obtain a good fluoroscopic image or for other purposes. In addition, a chemical liquid injector for injecting these chemical liquids has been put into practical use. For example, in a CT scanner, when injecting a contrast agent, the contrast agent injection is divided into a plurality of phases so that an optimal CT value can be obtained within the scanning period of the CT apparatus, and the injection rate is increased for each phase. Attempts have been made to change or to change the contrast agent concentration.

For example, in Patent Document 1, the total amount of medicinal solution is calculated based on the body weight of a subject, and the calculated amount of medicinal solution is injected at a predetermined time with an infusion protocol in which the infusion rate is changed according to a pre-registered infusion pattern. A chemical injection device for injection is described. Further, Patent Document 2 describes a chemical solution injector capable of freely setting an injection protocol by drawing an injection pattern on an injection graph displayed on a touch panel using a pen input device.
Patent Document 1: Japanese Patent Application Laid-Open No. 2004-113475 Patent Document 2: Japanese Patent Application Laid-Open No. 2004-298549

  However, in the chemical injection device described in Patent Document 1, there is only one type of injection pattern that is set in advance, and the operator cannot arbitrarily change the injection pattern. In addition, the operator cannot recognize the injection pattern in which the chemical solution is injected.

  On the other hand, the chemical injection device described in Patent Document 2 can arbitrarily create a desired injection pattern. However, in practice, injection patterns are often classified into several typical patterns, and it is troublesome to create a similar injection pattern each time.

  In order to solve these problems, it is conceivable that a plurality of injection patterns are registered in advance so that the operator can select one of these injection patterns. However, in this case, a new problem that the operator may select the injection pattern by mistake may occur, so it is important to prevent an erroneous selection by the operator.

  The objective of this invention is providing the chemical | medical solution injection | pouring apparatus with which an operator can set an injection | pouring pattern easily and so that a mistake may not arise.

In order to achieve the above object, a chemical liquid injection device according to the present invention includes a chemical liquid injection means, a pattern storage means for storing a plurality of injection patterns of chemical liquid as data, and one of injection patterns stored in the pattern storage means. An input means for selecting, a display means for displaying the selected injection pattern in a graph showing the injection time on the horizontal axis, an injection protocol generating means for generating an injection protocol based on the graph, and a liquid injection means Control means for controlling the operation, data input means for data input, and chemical liquid injection amount determining means for determining the injection amount of the chemical liquid using data input from the data input means . The injection patterns stored in the pattern storage means are different from each other in the temporal change in the injection state from the start to the end of the injection of the chemical solution. The control means controls the operation of the chemical solution injection means so that the chemical solution is injected according to the injection protocol created by the injection protocol creation means. The injection protocol creating means determines the injection rate of the chemical solution so that the injection amount of the chemical solution determined by the chemical solution injection amount determination means is injected at a predetermined injection time according to the selected pattern. Create a protocol.

In the chemical injection device of the present invention, the graph displayed on the display means may be expressed by an injection speed with the vertical axis expressed as a relative value. Furthermore, liquid injection quantity determining means, and Turkey to determine the injection amount of the liquid medicine on the basis of at least the subject's body weight is preferred.

  The input means may have a plurality of pattern selection operation units each displaying symbols corresponding to the plurality of injection patterns stored in the pattern storage means. In this case, the chemical solution injection unit is configured to be able to inject two types of chemical solutions, and the injection pattern stored in the pattern storage unit can include an injection pattern in which two types of chemical solutions are injected simultaneously. Furthermore, the input means may have a chemical solution selection operation unit for selecting at least one of the two types of chemical solutions.

  In the present invention, “relative value” is used to mean “absolute value”.

  According to the present invention, a plurality of injection patterns are stored in advance in the pattern storage means, and when creating an injection protocol, it is only necessary to select one of the injection patterns stored in the pattern storage means. Patterns can be set very easily. Moreover, since the selected injection pattern is displayed as an injection graph on the display means, the selected injection pattern can be intuitively recognized, and as a result, erroneous selection of the injection pattern can be prevented. In particular, when a graph is created based on the relationship between the injection rate expressed as a relative value and the injection time, the graph profile is the same regardless of the actual injection rate, so a common profile is used even when the injection volume changes. can do.

1 is a perspective view of an example of a chemical liquid injection system to which the present invention is applied. It is a perspective view of the chemical injection device shown in FIG. It is a perspective view which shows the injection | pouring head shown in FIG. 2 with the syringe with which it is mounted | worn. FIG. 3 is a block diagram showing the function of the chemical liquid injector shown in FIG. 2. It is a figure which shows an example of the screen displayed on a display part. It is a figure which shows the other example of the injection | pouring graph displayed on a display part.

Explanation of symbols

DESCRIPTION OF SYMBOLS 100 Chemical solution injection apparatus 101 Injection control unit 110 Injection head 121 Input part 122 Display part 124 Injection protocol preparation part 125 Control part 130 Piston drive mechanism 151,152 Chemical solution selection button 160 Injection graph 170 Pattern selection button group 300 CT scanner 1000 Perspective imaging system

  Next, embodiments of the present invention will be described with reference to the drawings.

  Referring to FIG. 1, there is shown a fluoroscopic imaging system 1000 that is an example of a chemical liquid injection system to which the present invention is applied, which has a chemical liquid injection device 100 and a CT scanner 300 that is a fluoroscopic imaging device. The CT scanner 300 is connected to the chemical injection device 100 in a wired manner, and includes a scanner main body 301 that executes an imaging operation, and a control unit 302 that controls the operation of the scanner main body 301.

  For example, as shown in FIG. 2, the chemical injection device 100 includes an injection head 110 that is an injection means mounted on the top of a stand 111 via an arm 112, and an injection control unit that is connected to the injection head 110 and a cable 102. 101. The injection control unit 101 includes a main operation panel 103, a touch panel 104 serving as a display unit and an input unit, a hand unit 107 serving as an auxiliary input unit connected by a cable 108, and the like.

  As shown in FIG. 3, the injection head 110 has two concave portions 114 formed as a syringe holding mechanism on the upper surface of the head main body 113, and the two syringes 200 </ b> C and 200 </ b> P are attached to the concave portion 114. The syringes 200 </ b> C and 200 </ b> P have a cylinder 210 and a piston 220. For example, the syringe 200C is filled with a contrast medium for CT as a chemical solution, and the syringe 200P is filled with physiological saline. The tips of the two syringes 200 </ b> C and 200 </ b> P attached to the head main body 113 are connected by a connecting tube 230. Also, two piston drive mechanisms 130 that are driven independently of each other are provided corresponding to the two recesses 114, and the piston 220 of each syringe attached to the recess 114 is pushed by each piston drive mechanism 130. Thus, it is possible to inject a contrast agent, inject physiological saline, and simultaneously inject both.

  As the general configuration of the piston drive mechanism 130 and its control mechanism, known configurations described in Patent Documents 1 and 2 can be adopted.

  FIG. 4 is a block diagram functionally showing the chemical liquid injector 100. Each block shown in FIG. 4 exists as at least a part of the configuration described in FIGS. 1 to 3 or a combination of at least a part thereof, and may be configured as hardware or as a logic circuit. It may be configured.

  In FIG. 4, an input unit 121 corresponds to the main operation panel 103 and the touch panel 104 shown in FIG. 2, and various settings related to the chemical injection device 100 by the operator, determination of the injection amount of the chemical, and determination of the injection protocol of the chemical Used to input data necessary for The display unit 122 corresponds to the touch panel 104 shown in FIG. 2, and displays a setting screen, a data input screen, a screen representing an operation state, and the like of the chemical liquid injector 100.

  The injection amount determination unit 123 determines the amount of the chemical solution to be injected into the subject using a part of the data input from the input unit 121. The optimal value for injecting the chemical into the subject is the optimal value for capturing a good image, subject factors such as the subject's weight, height, sex, age, components of the chemical, chemical factors such as physical properties, and imaging site, It depends on imaging factors such as imaging time and chemical injection protocol.

  For example, when the drug solution is a contrast medium, one important factor for obtaining a good image is the total amount of iodine injected. Contrast agents have different iodine concentrations depending on the type, and different types of contrast agents have different amounts of iodine contained in the same amount.

  Therefore, coefficient data for each imaging region, effective component data for each type of drug solution (for example, in the case of contrast medium, iodine-containing concentration data for each type of contrast medium), and information on drugs corresponding to physical information such as the body weight and height of the subject. Total injection amount data and the like are stored in the database 126.

  The injection amount determination unit 123 calculates the injection amount of the chemical solution by referring to the database 126 and applying a calculation formula determined in advance in consideration of these various factors. The calculation procedure of the injection amount of the chemical solution in the injection amount determination unit 123 may be the same as the calculation procedure of the injection amount of the chemical solution in the conventional chemical injection device. Description is omitted.

  The injection protocol creation unit 124 creates a chemical solution injection protocol using part of the data input from the input unit 121 and the injection amount determined by the injection amount determination unit 123.

  In order to make it easy for the operator to visually understand the injection protocol to be created, the injection protocol creation unit 124 displays, for example, a screen 150 as shown in FIG. 5 on the touch panel 104 (see FIG. 2) when creating the injection protocol.

  In the example illustrated in FIG. 5, chemical solution selection buttons 151 and 152, a determination button 154, a deletion button 155, an injection graph 160, and a pattern selection button group 170 are displayed on the screen 150.

  The chemical liquid selection buttons 151 and 152 are used to select which one of the piston drive mechanisms 130 (see FIG. 2) corresponds to the two piston drive mechanisms 130 (to be created). It is a button, and two types of chemicals are indicated by “A” and “B”. In this embodiment, the drug solution A is a contrast agent, and the drug solution B is a physiological saline. Adjacent to each of the chemical solution selection buttons 151 and 152, the injection amount of each chemical solution obtained by the injection amount determination unit 123 (see FIG. 4) is displayed.

  The injection graph 160 is a graph in which the vertical axis represents the injection rate of the chemical solution with the relative value, and the horizontal axis represents the injection time. The injection protocol is not displayed on the initial screen.

  The decision button 154 is operated when the injection protocol displayed on the injection bluff 160 is determined. The delete button 155 is operated when the injection protocol displayed on the injection bluff 160 is deleted.

  The pattern selection button group 170 is for selecting one of a plurality of injection patterns having different temporal changes in the injection speed from the start to the end of the injection of the chemical solution, and corresponds to the plurality of injection patterns. Thus, it has a plurality of buttons each displaying a pattern similar to the profile of the injection pattern displayed on the injection graph 160. Thereby, when an operator selects an injection pattern, each injection pattern can be recognized intuitively.

  In the example shown in FIG. 5, pattern buttons representing seven patterns 1 to 7 are displayed in the pattern selection button group 170. Briefly describing each pattern, pattern 1 is a pattern in which the injection rate increases linearly over time, pattern 2 is a pattern in which the injection rate decreases linearly over time, and pattern 3 is an injection process A pattern in which the chemical solution is injected at a constant injection rate until halfway, and thereafter the injection rate decreases linearly with the passage of time. Pattern 4 has a linear injection rate with the passage of time until the middle of the injection process. In the pattern 5 in which the chemical solution is injected at a constant injection rate thereafter, the injection rate of the chemical solution A linearly decreases with time, and the injection rate of the chemical solution B linearly increases with time. Pattern 6 in which chemical solutions A and B are injected simultaneously, pattern 6 is a pattern in which chemical solutions are injected at a constant injection rate from the start to the end of injection. Te, pattern 7, the solution A at a greater injection rate than the chemical B, and a pattern which simultaneously injected at a constant injection rate solution A, the B to the end from the injection start. These patterns 1 to 7 are stored in advance in the database 126 as graph profile data indicated by the relationship between the injection time and the injection speed. That is, the database 126 includes pattern storage means in the present invention.

  The injection graph 160 displays one of the selected patterns 1 to 7 when the operator selects an injection pattern. Although seven types of injection patterns are shown in this embodiment, the number of registered injection patterns is not limited to this as long as there are a plurality of types, and the number can be increased or decreased according to the specifications of the chemical solution injection device.

  In addition to this, the screen 150 can display subject information such as a subject's ID and weight, and imaging information such as an imaging region.

  Each of the pattern buttons of the chemical solution selection buttons 151 and 152, the determination button 154, the deletion button 155, and the pattern selection button group 170 can be operated by tapping each display position with a pen or an operator's finger. it can.

  A plurality of time display boxes 161 are displayed at positions corresponding to the scale of the horizontal axis (injection time) in the injection graph 160. The injection time substantially coincides with the imaging time by the CT scanner 300 (see FIG. 1), and the injection time corresponding to the imaging time sent from the CT scanner 300 is displayed in the rightmost time display box 161. In the other time display box 161, for example, when the pattern 3 or 4 is selected, the slope of the injection graph changes, or when the pattern 5 is selected, the injection speeds of the two chemical solutions match. The time at the characteristic point of the implantation pattern is displayed according to the selected implantation pattern and implantation time.

  Data relating to the imaging time can be obtained not from the CT scanner 300 but from an external database (not shown). Alternatively, the injection time data for the imaging region can be stored in the database 126 (see FIG. 4), and the injection time can be set from here. Furthermore, the value displayed in the time display box 161 can be set as a default value, and can be arbitrarily changed by the operator.

  Referring to FIG. 4 again, the control unit 125 injects into the injection amount determination unit 123 and the injection protocol creation unit 124 based on the operation of the injection control unit 101 by the operator through the input unit 121 and data input, respectively. Calculation commands for determining the amount and creating the injection protocol are issued, and predetermined data, graphs, and the like are displayed on the display unit 122 based on the calculation results of the injection amount determining unit 123 and the injection protocol creating unit 124. Further, the control unit 125 controls the operation of each piston drive mechanism 130 so as to inject the medicinal solution of the injection amount determined by the injection amount determination unit 123 in accordance with the injection protocol created by the injection protocol creation unit 124.

  In this embodiment, since the data input for determining the injection amount and creating the injection protocol is performed on the screen displayed on the touch panel 104, the control unit 125 uses the touch panel 104 for the data input. Also performs screen display control.

  Next, an example of the chemical solution injection operation by the chemical solution injection apparatus 100 will be described with reference to the respective drawings described above.

  The operator attaches the syringes 200 </ b> P and 200 </ b> C to the injection head 110 while the power of the chemical liquid injection device 100 is on. After mounting the syringes 200P and 200C, the operator connects the extension tube to the syringes 200P and 200C via the connecting tube 230, and inserts an injection needle (not shown) provided at the tip of the extension tube into the subject. .

  Thereafter, when the operator operates a start button provided on the main operation panel 103, a screen for determining the injection amount is displayed on the touch panel 104.

  On the screen for determining the injection volume, images for inputting the imaging region, the weight of the subject, and the type of the medicinal solution to be injected are displayed sequentially or collectively, and the operator determines at least the weight of the subject according to this image. input. In particular, in the image for entering the type of chemical solution, if the chemical solution is a contrast agent or physiological saline, or if the chemical solution is a contrast agent, an input image of data necessary to specify the iodine-containing concentration Is also displayed.

  When the input of all data is completed, the operator operates a confirmation button (not shown) displayed on the touch panel 104. By operating the confirmation button, the input data is sent to the injection amount determination unit 123, where the injection amount is determined.

  After the injection amount is determined, a signal indicating that the determination of the injection amount is completed is sent to the control unit 125, and the determined injection amount data is sent to the injection protocol creation unit 124. When a signal indicating that the determination of the injection amount is completed is sent to the control unit 125, the control unit 125 sends a command for creating the injection protocol to the injection protocol creation unit 124, and for example, as shown in FIG. A screen 150 for creating an injection protocol is displayed on the touch panel 104.

  When the injection protocol creation screen 150 is displayed on the touch panel 104, the operator determines which chemical injection protocol to create according to the displayed screen 150, either of the two chemical solution selection buttons 151, 152. Select by manipulating one or both. The determination of the drug solution for which the injection protocol is to be created can be performed, for example, by the operator operating the decision button 154 after selecting the drug solution.

  Next, the operator selects an injection pattern of the selected chemical solution from patterns 1 to 7. The injection pattern is selected by operating one of a plurality of pattern buttons displayed on the pattern selection button group 170. When an injection pattern is selected, the injection protocol creation unit 124 reads profile data of the selected injection pattern from the database 126 according to a command from the control unit 125. On the other hand, the control unit 125 controls the touch panel 104 so that the selected injection pattern is displayed on the injection graph 160.

  For example, when pattern 3 (a pattern in which a chemical solution is injected at a constant injection rate until the end of injection and thereafter the injection rate linearly decreases with time) is selected on the screen 150 of the touch panel 104. Shows an injection graph 160 as shown in FIG. The time display box 161 displays the injection time based on the imaging time data sent from the CT scanner 300 (see FIG. 1). At this time, the time at which the injection rate decreases may also be displayed.

  The operator confirms the profile of the injection pattern displayed on the injection graph 160 and corrects the time displayed in the time display box 161 as necessary.

  After confirming the injection pattern, etc., if the injection pattern displayed on the injection graph 160 is acceptable, the operator operates the decision button 154. As a result, the control unit 125 sends an injection protocol creation command to the injection protocol creation unit 124, and the injection protocol creation unit 124 sends a predetermined amount of the medicinal solution according to the injection pattern displayed on the injection graph 160. An infusion protocol is created by determining the actual infusion rate of the drug solution to be infused over time. The created injection protocol is sent to the control unit 125.

  Thereafter, the control unit 125 switches the display on the touch panel 104 to a screen for injection, and creates a control sequence for the piston drive mechanism 130 based on the injection protocol sent from the injection protocol creation unit 124.

  An injection start button is displayed on the injection screen. When this button is operated by the operator, the control unit 125 controls the piston drive mechanism 130 according to the created control sequence. Thereby, the drug solution is injected into the subject according to the created injection protocol.

  As described above, in the chemical injection device 100 of this embodiment, a plurality of injection patterns are registered in advance, and an injection pattern can be set very easily by allowing an operator to arbitrarily select among them. can do. In addition, in this embodiment, since the injection pattern selected by the operator is displayed on the injection graph 160, the operator can intuitively recognize the selected injection pattern. As a result, it is possible to prevent an erroneous selection of the implantation pattern.

  Furthermore, in this embodiment, an injection graph is created with the injection rate of the chemical solution represented by a relative value as the vertical axis, and an actual injection rate corresponding to the injection amount and the injection time is obtained based on the created injection graph. . Therefore, the operator can select the injection pattern and set the injection time or the like as necessary, thereby injecting a predetermined amount of chemical solution within a predetermined time.

  In addition, since the injection graph 160 represents the injection rate as a relative value, the profile of the injection graph 160 is the same even when the actual injection rate changes due to the difference in the injection amount. Therefore, the same profile can be used even when the injection amount changes. In particular, if the created infusion graph data is stored in, for example, the database 126 in the infusion control unit 101 or a database provided separately from it, the stored infusion protocol can be read out as necessary. Each time changes, there is no need to create a new injection graph 160.

  In the above-described embodiment, an example in which the injection rate is expressed as a relative value has been shown. Can be replaced with a graph converted to a numerical value corresponding to the actual injection rate obtained. In actual injection, the value of the injection rate itself is important as well as the change with time of the injection state. Accordingly, by displaying an injection graph with the vertical axis representing the actual injection rate, the operator can also determine the validity of the created injection protocol.

  Alternatively, an injection protocol can be created by using an injection graph in which the vertical axis indicates the actual injection speed from the beginning. In this case, since the injection amount is determined from the relationship between the injection speed and the injection time at the stage where the injection graph is created, the injection amount may not be determined in advance.

  For the vertical axis of the injection graph, in addition to the above-described injection speed, any variable that can be changed with time during the injection of the chemical solution can be used. For example, the vertical axis can also be indicated by the amount of medicinal solution injected. The injection amount may be a cumulative injection amount, or the total injection time may be divided into a plurality of time zones of equal intervals or unequal intervals and indicated by relative values for each time zone.

  Further, in the above-described embodiment, an example in which the touch panel 104 is used and the display unit and the input unit when creating the injection protocol are shared is shown, but the display unit is not necessarily the touch panel 104. In this case, for example, the injection graph 160 shown in FIG. 5 is displayed on the display unit, but other operation buttons such as the chemical solution selection buttons 151 and 152 and the pattern selection button group 170 are displayed on the display unit. Separately, it is provided in an input unit such as an operation panel (not shown).

  Further, in the above-described embodiment, the injection control unit 101 has been described as including the injection amount determining unit 123 that calculates the injection amount of the drug solution from the body weight data of the subject input by the operator. However, the injection control unit does not have the injection amount determination unit 123, and the operator may directly input the injection amount of the chemical solution.

  In the above-described embodiment, the example in which the chemical solution is continuously injected from the start to the end of the injection has been shown. However, an interval for temporarily interrupting the injection of the chemical solution may be provided during the injection process of the chemical solution. In this case, it is preferable that the interval time can be set on the injection graph.

Claims (7)

Chemical injection means;
A pattern storage means for storing, as data, a plurality of injection patterns each having a different time-dependent change pattern of the injection state from the start to the end of the injection of the chemical solution;
Input means for selecting one of a plurality of injection patterns stored in the pattern storage means;
Display means for displaying the selected injection pattern in a graph showing the injection time on the horizontal axis;
Injection protocol creating means for creating an injection protocol based on the graph;
A control unit that controls the operation of the chemical solution injection means so that the chemical solution is injected in accordance with the injection protocol created by the injection protocol creation means;
Data input means for data input;
A chemical injection amount determining means for determining an injection amount of the chemical liquid using data input from the data input means;
I have a,
The injection protocol creation means determines the injection speed of the chemical solution so that the injection liquid amount determined by the chemical injection amount determination means is injected at a predetermined injection time according to the selected injection pattern. A chemical solution injection device that creates the injection protocol by The graph ordinate is indicated by infusion rate, expressed in relative value, liquid injector according to claim 1. The liquid medicine injection amount determining means, that determine the injection amount of the liquid medicine on the basis of at least the subject's weight, liquid injector according to claim 1 or 2.   4. The chemical solution according to claim 1, wherein the input unit includes a plurality of pattern selection operation units each displaying a pattern corresponding to a plurality of injection patterns stored in the pattern storage unit. 5. Injection device. The chemical solution injection means is configured to be able to inject two types of chemical solutions,
The chemical | medical solution injection apparatus of Claim 4 with which the injection | pouring pattern stored in the said pattern storage means contains the injection | pouring pattern which inject | pours two types of chemical | medical solutions simultaneously.   The chemical input device according to claim 5, wherein the input unit further includes a chemical selection operation unit for selecting at least one of the two types of chemicals. The chemical solution injection device according to any one of claims 1 to 6, further comprising a syringe that is attached to the chemical solution injection unit and is filled with the chemical solution.

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