JP2019111445A - X-ray diagnostic apparatus - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an X-ray diagnostic apparatus capable of improving inspection efficiency. An X-ray tube 7 generates X-rays. The X-ray detector 10 detects the X-rays generated from the X-ray tube 7. The mounting surface 11 is held between the X-ray tube 7 and the X-ray detector 10, and has a mounting portion for a subject and a mounting portion for a specimen collected from the subject. The mounting table support mechanism 3 supports the X-ray detector 10 and the mounting surface 11. The X-ray tube support mechanism 4 rotatably supports the X-ray tube 7 around a predetermined rotation axis. The irradiation field limiter 33 limits the solid angle of X-rays generated from the X-ray tube 7. By controlling the X-ray tube support mechanism 4 and the irradiation field limiting device 33, the imaging control unit 29 sets the irradiation field on the mounting surface 11 of the X-rays generated from the X-ray tube 7 on the mounting surface 11. Selectively switch between the placement portion for the subject and the placement portion for the specimen. [Selection diagram] Fig. 1

Description

  Embodiments of the present invention relate to an X-ray diagnostic apparatus.

  BACKGROUND There is a mammography test for detecting breast cancer using a breast X-ray diagnostic apparatus (hereinafter referred to as a mammography apparatus). When a mammographic examination finds a lesion such as calcification that is suspected of being malignant, the examiner uses the stereographic imaging function of the mammography device to locate the lesion. The examiner inserts a collection needle of a dedicated instrument (Mammatome) at the determined position of the lesion, and aspirates and collects the tissue. The examiner diagnoses the diseased tissue collected. This procedure is called mammography-guided biopsy test (hereinafter referred to as biopsy test).

  In the biopsy test, the examiner performs X-ray imaging of the collected tissue specimen using an X-ray imaging apparatus for specimen imaging to confirm whether the target calcified tissue can be collected. If it is confirmed that the target has not been collected, the examiner collects tissue samples again. In order to confirm a lesion in a tissue sample, image quality characteristics (low energy X-ray, high resolution, high contrast, etc.) unique to a mammography device are desirable rather than a general X-ray diagnostic device.

  The X-ray imaging (stereo imaging) of the breast and the X-ray imaging of the sample in the biopsy examination are performed using separate X-ray diagnostic apparatuses. Specifically, stereo imaging of the breast is performed using a mammography device. X-ray imaging of a specimen is performed using an X-ray diagnostic apparatus used for other examinations. The X-ray diagnostic device used for other examinations must be moved to another place for imaging a tissue sample, because the mammography system is located at a different place in the examination facility. , Burden on the examiner's subject. Furthermore, since the X-ray diagnostic apparatus is not a dedicated apparatus for imaging a tissue sample, it is difficult to secure the image quality such as high resolution and high contrast required for an X-ray image of the tissue sample.

  X-ray imaging of a specimen in biopsy examination may be performed using a mammography apparatus. The examiner determines the position of the lesion by stereo imaging of the breast and positions the collection needle. Subsequently, the examiner inserts a collection needle of Mammotome at the determined position of the breast and takes a tissue sample. At this time, the breast is fixed to the mounting surface of the mammography apparatus by the compression plate. However, here, in order to radiograph a sample using the same mammography apparatus, it is necessary to replace the breast fixed to the mounting surface with the sample. Specifically, it is necessary to remove the collection needle inserted into the breast, release the fixation of the breast fixed to the mounting surface, remove the breast from the mounting surface, and place the sample on the mounting surface. In the biopsy test, if it is confirmed that the target can not be collected, the examiner should collect tissue samples again. Therefore, if it is confirmed that the target can not be collected, the subject must return to the hospital and undergo a biopsy test again, which is a burden on the subject.

JP, 2008-272093, A

  An object is to provide an X-ray diagnostic apparatus capable of improving inspection efficiency.

  An X-ray diagnostic apparatus according to the present embodiment includes an X-ray tube generating X-rays, an X-ray detector detecting X-rays generated from the X-ray tube, the X-ray tube, and the X-ray detector An X-ray detector, and a mounting surface, the mounting surface having a mounting portion for a subject and a mounting portion for a sample collected from the subject; A support table supporting mechanism, an X-ray tube support mechanism rotatably supporting the X-ray tube around a predetermined rotation axis, and a solid angle of X-rays generated from the X-ray tube The irradiation field on the mounting surface of the X-ray tube generated from the X-ray tube by controlling the radiation field limiter of the variable opening, the X-ray tube support mechanism, and the irradiation field limiter is described above. Imaging control unit that selectively switches between a mounting portion for the subject and a mounting portion for the sample , Comprising a.

BRIEF DESCRIPTION OF THE DRAWINGS The figure which shows the structure of the X-ray diagnostic apparatus which concerns on this embodiment. BRIEF DESCRIPTION OF THE DRAWINGS The figure which shows an example of the external appearance of the X-ray diagnostic apparatus which concerns on this embodiment. The figure which shows an example of the mounting surface of FIG. The figure which shows the other example of the mounting surface of FIG. The figure which shows an example of the switching corresponding | compatible table regarding irradiation field switching. The figure for demonstrating the irradiation field switching to the irradiation field F1. The figure for demonstrating the irradiation field switching to the irradiation field F2. The figure for demonstrating the irradiation field switching to the irradiation field F3. The figure for demonstrating the irradiation field switching to the irradiation field F4. The figure which shows an example of the corresponding | compatible table which shows the response | compatibility with the X-ray condition and image process about each irradiation field regarding irradiation field switching. The figure which shows typically the typical flow of the biopsy test which concerns on this embodiment. The figure which shows an example of the breast stereo image which concerns on this embodiment. The figure which shows an example of the sample X-ray image which concerns on this embodiment. FIG. 16 is a view showing a display example of a breast X-ray image and a sample X-ray image by the display unit according to Application Example 1; FIG. 17 is a view showing a display example of a breast stereo image and a sample X-ray image by the display unit according to Application Example 2; FIG. 18 is a view showing a display example of a breast cross-sectional image and a sample X-ray image by the display unit according to application example 3; The figure which shows an example of the biopsy test | inspection report which concerns on the example 4 of application. The figure which shows an example of the X-ray protection mechanism of the mounting base installation type which concerns on the application example 5. FIG. The figure which shows an example of the X-ray protection mechanism of the sampling system installation type which concerns on the example 5 of application.

  Hereinafter, the X-ray diagnostic apparatus 1 according to the embodiment will be described with reference to the drawings. In the following description, components having substantially the same function and configuration are given the same reference numerals, and redundant description will be made only when necessary.

  The subject according to the present embodiment is assumed to be a breast.

  FIG. 1 is a diagram showing the configuration of the X-ray diagnostic apparatus 1. The X-ray diagnostic apparatus 1 has an imaging mechanism 2. FIG. 2 is a view showing an example of the appearance of the X-ray diagnostic apparatus 1. As shown in FIG. 2, the imaging mechanism 2 has a mounting table support mechanism 3 and an X-ray tube support mechanism 4. The mounting table support mechanism 3 and the X-ray tube support mechanism 4 are connected to a shaft 6 mounted horizontally on the support 5. The mounting table support mechanism 3 and the X-ray tube support mechanism 4 are supported by the columns 5 so as to be separately rotatable as the central axis R of the axis of the shaft 6. The rotation direction around the rotation center axis R is taken as the β direction.

  An X-ray tube 7 is provided at the end of the X-ray tube support mechanism 4. The X-ray tube 7 receives the application of a high voltage and the supply of a filament current from the high voltage generator 8 to generate X-rays.

  A mounting table 9 is provided at the end of the mounting table support mechanism 3 so as to face the X-ray tube 7. An X-ray detector 10 is provided inside the mounting table 9. The X-ray detector 10 is realized by, for example, a flat panel detector (hereinafter, referred to as FPD). The FPD has a plurality of elements arranged in a two-dimensional manner. Each element detects X-rays generated from the X-ray tube 7 and converts the detected X-rays into electrical signals. An electrical signal generated in each element is output to an analog to digital converter (hereinafter referred to as an A / D converter) not shown. The A / D converter converts the electrical signal into digital data. The A / D converter outputs digital data to the image generator 21.

  The rotation angle of the X-ray tube support mechanism 4 is defined as a rotation angle around the rotation center axis R with the uppermost part of the circular orbit O being 0 °. The rotation angle of the mounting table support mechanism 3 is defined as a rotation angle around the rotation center axis R, where the uppermost part of the same circular orbit O as the X-ray tube support mechanism 4 is 0 °. When the rotation angle of the mounting table support mechanism 3 is 0 °, the detection surface of the X-ray detector 10 is horizontal to the installation surface of the X-ray diagnostic apparatus 1.

  The mounting table 9 has a mounting surface 11 on the surface facing the X-ray tube 7. The compression plate 12 is attached to the mounting table support mechanism 3 so as to be movable between the mounting surface 11 and the X-ray tube 7 in a direction approaching or separating from the mounting surface 11. The direction in which the mounting surface 11 and the compression plate 12 approach or separate from each other is referred to as an arrow α direction. The mounting surface 11 is provided for compressing the breast in a slab shape, together with the compression plate 12 supported by the mounting table support mechanism 3 so as to be movable in the arrow α direction.

  Further, the mounting table support mechanism 3 is equipped with a sampling mechanism 13 above the mounting table 9. In the sample collecting mechanism 13, a collection driving unit 15 for driving the sample collecting mechanism 13 to collect a tissue sample under the control of the collection control unit 14 is incorporated. The sampling mechanism 13 has a collection needle 16 for collecting a tissue sample. The collection needle 16 is movable in the arrow α direction by the power of the sampling drive unit 15. The sampling mechanism 13 and the collection needle 16 are positioned so that the collection needle 16 can pass through the through hole formed in the center of the compression plate 12. The sample collecting mechanism 13 may be equipped at a portion other than the mounting table support mechanism 3. The sample collecting mechanism 13 may have a configuration that can be attached to and removed from the imaging mechanism 2.

  The X-ray diagnostic apparatus 1 according to the present embodiment includes an image generation unit 21, an image processing unit 22, a reconstruction unit 23, an association unit 24, an input unit 25, a storage unit 26, a display unit 27, an interface unit along with the imaging mechanism 2. An imaging control unit 29, an X-ray control unit 30, a drive control unit 31, and a system control unit 32 are provided.

  The image generator 21 performs preprocessing on the digital data output from the X-ray detector 10 to generate an X-ray image. The image pre-processing is correction of uneven sensitivity between channels in the X-ray detector 10, correction regarding dropout, and the like. The image generation unit 21 outputs the generated X-ray image to the storage unit 26 described later.

  The image processing unit 22 performs contrast processing, frequency processing, dynamic range processing, noise reduction processing, and the like on an X-ray image acquired from a storage unit 26 described later.

  The reconstruction unit 23 reconstructs a cross-sectional image based on a plurality of X-ray images regarding a plurality of positions of the X-ray tube 7.

  The association unit 24 generates an image by stereo imaging with a breast as an imaging target (hereinafter referred to as a breast stereo image), an X-ray image with a sample as an imaging target (hereinafter referred to as a sample X-ray image), and mammography examination An X-ray image (hereinafter referred to as a breast X-ray image) in which the entire breast having been photographed is to be imaged is associated as a DICOM image of the same subject. An X-ray image in which both a breast and a specimen are to be imaged may be associated as a DICOM image of the same subject.

  The input unit 25 inputs an X-ray condition desired by the examiner, an X-ray imaging position, start and end of X-ray imaging, and the like. The input unit 25 inputs various instructions from the inspector or the like, instructions, information, selection, settings, and the like to the system control unit 32 described later.

  The storage unit 26 stores the instruction of the examiner supplied from the input unit 25. The storage unit 26 stores various data. The switching correspondence table may be changed by the examiner via the input unit 25. In addition, the storage unit 26 may store the X-ray image generated by the image generation unit 21, the X-ray image processed by the image processing unit 22, the X-ray image reconstructed by the reconstruction unit 23, and the like. good. The storage unit 26 appropriately outputs the stored X-ray image to the image processing unit 22, the reconstruction unit 23, the display unit 27, the interface unit 28, and the like.

  The display unit 27 displays various information on the monitor. For example, the display unit 27 displays the X-ray image generated by the image generation unit 21 and the X-ray image subjected to image processing by the image processing unit 22. In addition, the display unit 27 may read and display arbitrary image data stored in the storage unit 26.

  The interface unit 28 is connected to a Picture Archiving and Communication Systems (PACS) and other computers (not shown) via a network.

  The imaging control unit 29 controls the X-ray control unit 30 and the drive control unit 31 to cause the imaging mechanism 2 to perform X-ray imaging. The imaging control unit 29 controls the X-ray tube support mechanism 4 and the radiation field limiter 33 to make the radiation field on the placement surface 11 of the X-ray generated from the X-ray tube 7 It selectively switches between the breast placement part P1 and the sample placement part P2. In the case of a mammography examination, the imaging control unit 29 switches the irradiation field to the entire detection surface of the X-ray detector 10.

  The collection control unit 14 controls the collection drive unit 15 to cause the sample collection mechanism 13 to collect a tissue sample. The collection control unit 14 controls the collection drive unit 15 to collect a sample from the breast placed on the mounting surface 11.

  The system control unit 32 functions as a center of the X-ray diagnostic apparatus 1. The system control unit 32 comprehensively controls each component included in the X-ray diagnostic apparatus 1 to realize various operations according to the present embodiment.

  Hereinafter, an operation example of the X-ray diagnostic apparatus 1 according to the present embodiment will be described.

  First, the mounting surface 11 will be described. FIG. 3 is a view showing an example of the mounting surface 11 of FIG. The mounting surface 11 is a part of the surface of the mounting table 9 facing the X-ray tube 7. The mounting surface 11 has a breast mounting portion P1 and a sample mounting portion P2 collected from the breast. The sample mounting portion P2 is provided on the side of the mounting surface 11 on which the mounting table support mechanism 3 is installed. The breast placement portion P 1 is provided on the other side of the placement surface 11. The breast placement portion P1 and the sample placement portion P2 are provided apart from each other. The breast placement portion P1 and the sample placement portion P2 are provided at the end of the placement surface 11 in FIG. 3, but may be provided inside the placement surface 11 rather than the end. Also, in practice, the sample placement portion P2 is provided in a portion of the placement surface 11 that does not interfere with mammography inspection and biopsy inspection. Moreover, since the mounting surface 11 is inclined in a state where the breast and the sample are mounted, it is preferable that the mounting surface 11 be formed of a non-slippery material such as a resin having a high coefficient of friction. The sample mounting portion P2 has a first sample mounting portion P21 and a second sample mounting portion P22. The number of sample placement portions P2 may be one or three or more. FIG. 4 is a view showing another example of the mounting surface 11 of FIG. The case where the breast mounting part P1 and the sample mounting part P2 have different sizes is shown. As in FIG. 4, the size of the breast placement portion P1 and the sample placement portion P2 may be different.

  Next, irradiation field switching performed under the control of the system control unit 32 between the breast placement portion P1 and the sample placement portion P2 will be described. FIG. 5 is a diagram showing an example of a switching correspondence table regarding irradiation field switching. The switching correspondence table relates the rotation angle of the X-ray tube support mechanism 4 and the size and shape of the opening of the irradiation field limiter 33 for each of the plurality of radiation field targets. The aim of the radiation field is determined by the rotation angle of the X-ray tube support mechanism 4 and the size and shape of the opening of the radiation field limiter 33. Specifically, the radiation field relating to the present embodiment is classified into a radiation field for biopsy examination and a radiation field for mammography examination. The radiation fields for the biopsy examination are the radiation fields F1, F2 and F3, and the radiation field for the mammography examination is the radiation field F4. The radiation field F1 is defined as a radiation field aiming at the breast placement part P1. The rotation angle of the X-ray tube support mechanism 4 in the irradiation field F1 is θ1 + γ or θ1-γ, and the size and shape of the opening of the irradiation field limiter 33 are A1. The irradiation field F2 is defined as an irradiation field aiming at the first sample mounting portion P2. The rotation angle of the X-ray tube support mechanism 4 of the irradiation field F2 is θ2, and the size and shape of the opening of the irradiation field limiter 33 are A2. The radiation field F3 is defined as a radiation field aiming at the second sample mounting portion P2. The rotation angle of the X-ray tube support mechanism 4 of the irradiation field F3 is θ3, and the size and shape of the opening of the irradiation field limiter 33 are A3. The radiation field F4 is a radiation field for mammography examination. The radiation field F4 is defined as a radiation field aiming at the entire detection surface of the X-ray detector 10. The rotation angle of the X-ray tube support mechanism 4 in the irradiation field F4 is θ4, and the size and shape of the opening of the irradiation field limiter 33 are A4. The switching correspondence table is stored in advance in the storage unit 26.

  When the examiner inputs a switching instruction to the irradiation field F1 via the input unit 25, the system control unit 32 reads the switching correspondence table from the storage unit 26, and switches the irradiation field to the breast placement part P1. By setting the rotation angle of the X-ray tube support mechanism 4 to θ1 ± γ and the size and shape of the opening of the irradiation field limiter 33 to be A1, the irradiation field is switched to the breast placement portion P1. When the examiner inputs a switching instruction to the irradiation field F2 via the input unit 25, the system control unit 32 reads the switching correspondence table from the storage unit 26, and switches the irradiation field to the first sample mounting portion P21. By setting the rotation angle of the X-ray tube support mechanism 4 to θ 2 and the size and shape of the opening of the irradiation field limiter 33 to A 2, switching to the first specimen mounting portion P 21 is performed. When the examiner inputs a switching instruction to the irradiation field F3 via the input unit 25, the system control unit 32 reads the switching correspondence table from the storage unit 26, and switches the irradiation field to the second sample mounting portion P22. By setting the rotation angle of the X-ray tube support mechanism 4 to θ3 and the size and shape of the opening of the irradiation field limiter 33 to A3, the irradiation field is switched to the second sample mounting portion P22. When the examiner inputs a switching instruction to the irradiation field F4 via the input unit 25, the system control unit 32 reads the switching correspondence table from the storage unit 26, and the irradiation field is on the entire detection surface of the X-ray detector 10. Switch. By setting the rotation angle of the X-ray tube support mechanism 4 to θ 4 and the size and shape of the opening of the irradiation field limiter 33 to A 4, the irradiation field is switched over the entire detection surface of the X-ray detector 10. A sensing unit may be provided that senses the pressure applied to the sample placement portion P2, and irradiation field switching may be initiated when the sensing unit senses a pressure equal to or greater than a predetermined value.

  FIG. 6 is a diagram for explaining irradiation field switching to the irradiation field F1. The radiation field F1 is used in the case of breast stereography. In FIG. 6, the radiation field is shown to be aimed at the breast placement portion P1 on the placement surface 11. When an instruction to switch to the irradiation field F1 is input through the input unit 25, the system control unit 32 reads an item related to the irradiation field F1 from the switching correspondence table stored in the storage unit 26. The system control unit 32 controls the imaging control unit 29 based on the read correspondence table to perform irradiation field switching. The imaging control unit 29 issues an instruction signal to switch the irradiation field to the drive control unit 31. The drive control unit 31 changes the radiation angle to the breast placement portion P1 by changing the rotation angle of the X-ray tube support mechanism 4 and the opening of the radiation field limiter 33. Specifically, the X-ray tube support mechanism drive unit 34 sets the rotation angle of the X-ray tube support mechanism 4 to θ1 + γ or θ1-γ under the control of the drive control unit 31. In order to make the description specific, θ1 is 0 °, γ is 15 °, and the rotation angle θ1 ± γ is ± 15 °. Here, the rotation angles θ1 ± γ are a rotation angle on the positive side and a rotation angle on the negative side in breast stereo imaging. The opening driving unit 41 moves the diaphragm blade of the irradiation field limiter 33 by the control of the drive control unit 31, and changes the size and shape of the opening into A1. The opening degree of the diaphragm blade for realizing the size and shape A1 of the opening is stored in advance in the storage unit 26. In order to simplify the above description, the rotation angle of the mounting table support mechanism 3 is 0 °. The mounting table support mechanism drive unit 35 changes the rotation angle of the mounting table support mechanism 3 under the control of the drive control unit 31. When the rotation angle of the mounting table support mechanism 3 is ω, the rotation angle of the X-ray tube support mechanism 4 is read as + ω in the following description. The radiation field F1 may be used for normal breast radiography instead of breast stereo radiography.

  FIG. 7 is a diagram for explaining irradiation field switching to the irradiation field F2. In FIG. 7, the irradiation field indicates that the first specimen mounting portion P <b> 21 on the mounting surface 11 is aimed. When an instruction to switch to the irradiation field F2 is input through the input unit 25, the system control unit 32 reads an item related to the irradiation field F2 from the switching correspondence table stored in the storage unit 26. The system control unit 32 controls the imaging control unit 29 based on the read correspondence table to perform irradiation field switching. The imaging control unit 29 issues an instruction signal to switch the irradiation field to the drive control unit 31. The drive control unit 31 switches the irradiation field to the first sample mounting portion P21 by changing the rotation angle of the X-ray tube support mechanism 4 and the opening of the irradiation field limiter 33. Specifically, the X-ray tube support mechanism drive unit 34 sets the rotation angle of the X-ray tube support mechanism 4 to θ2 under the control of the drive control unit 31. For example, the rotation angle θ2 is 15 ° to make the description specific. The opening drive unit 41 moves the diaphragm blade of the irradiation field limiter 33 by the control of the drive control unit 31, and changes the size and shape of the opening into A2. The opening degree of the diaphragm blade for realizing the size and shape A2 of the opening is stored in advance in the storage unit 26.

  FIG. 8 is a diagram for explaining irradiation field switching to the irradiation field F3. In FIG. 8, the irradiation field indicates that the second sample placement portion P <b> 22 on the placement surface 11 is aimed. When an instruction to switch to the irradiation field F3 is input through the input unit 25, the system control unit 32 reads an item related to the irradiation field F3 from the switching correspondence table stored in the storage unit 26. The system control unit 32 controls the imaging control unit 29 based on the read correspondence table to perform irradiation field switching. The imaging control unit 29 issues an instruction signal to switch the irradiation field to the drive control unit 31. The drive control unit 31 switches the irradiation field to the second sample mounting portion P22 by changing the rotation angle of the X-ray tube support mechanism 4 and the opening of the irradiation field limiter 33. Specifically, the X-ray tube support mechanism drive unit 34 sets the rotation angle of the X-ray tube support mechanism 4 to θ3 under the control of the drive control unit 31. For example, the rotation angle θ3 is −15 ° to make the description specific. The opening driving unit 41 moves the diaphragm blade of the irradiation field limiter 33 by the control of the drive control unit 31, and changes the size and shape of the opening into A3. The opening degree of the diaphragm blade for realizing the size and shape A3 of the opening is stored in advance in the storage unit 26.

  FIG. 9 is a diagram for explaining switching of the irradiation field to the irradiation field F4 in the mammographic examination. The radiation field F4 is used in the case of mammography examination. In FIG. 9, the irradiation field indicates that the entire detection surface of the X-ray detector 10 on the placement surface 11 is aimed. When an instruction to switch to the irradiation field F4 is input through the input unit 25, the system control unit 32 reads an item related to the irradiation field F4 from the switching correspondence table stored in the storage unit 26. The system control unit 32 controls the imaging control unit 29 based on the read correspondence table to perform irradiation field switching. The imaging control unit 29 issues an instruction signal to switch the irradiation field to the drive control unit 31. The drive control unit 31 changes the irradiation field to the entire detection surface of the X-ray detector 10 by changing the rotation angle of the X-ray tube support mechanism 4 and the opening of the irradiation field limiter 33. Specifically, the X-ray tube support mechanism drive unit 34 sets the rotation angle of the X-ray tube support mechanism 4 to θ4 under the control of the drive control unit 31. In order to make the description specific, the rotation angle θ4 is 0 °. The opening drive unit 41 moves the diaphragm blade of the irradiation field limiter 33 by the control of the drive control unit 31, and changes the size and shape of the opening into A4. The opening degree of the diaphragm blade for realizing the size and shape A4 of the opening is stored in advance in the storage unit 26.

  Subsequently, the X-ray condition switching and the image processing switching which are performed under the control of the system control unit 32 when the irradiation field is switched will be described. FIG. 10 is a diagram showing an example of a correspondence table showing correspondence between X-ray conditions and image processing for each irradiation field related to irradiation field switching. The correspondence table defines X-ray conditions and image processing for each irradiation field. In the case of the irradiation field F1, the X-ray condition is X1, and the image processing is P1. In the case of the irradiation field F2, the X-ray condition is X2 and the image processing is P2. In the case of the irradiation field F3, the X-ray condition is X3 and the image processing is P3. In the case of the irradiation field F4, the X-ray condition is X4, and the image processing is P4. The correspondence table is stored in advance in the storage unit 26. At the time of switching to the irradiation field F1, the X-ray condition is switched to X1 and the image processing is switched to P1. At the time of switching to the irradiation field F2, the X-ray condition is switched to X2 and the image processing is switched to P2. When switching to the irradiation field F3, the X-ray condition is switched to X3 and the image processing is switched to P3. At the time of switching to the irradiation field F4, the X-ray condition is switched to X4, and the image processing is switched to P4.

  When the examiner inputs an irradiation field switching instruction via the input unit 25, X-ray condition switching is performed in conjunction with the irradiation field switching. Specifically, the system control unit 32 reads the correspondence table stored in the storage unit 26. The system control unit 32 controls the imaging control unit 29 based on the read correspondence table, and outputs an instruction signal for X-ray condition switching to the X-ray control unit 30. The X-ray control unit 30 switches the X-ray conditions to X1, X2, X3 and X4 according to the irradiation fields F1, F2 and F3. The X-ray conditions X1, X2, X3, and X4 are stored in advance in the storage unit 26. The X-ray conditions X1, X2, X3, and X4 may be changed by the examiner via the input unit 25. The differences between the X-ray conditions X1, X2, X3 and X4 are, for example, X-ray tube voltage, tube current time product, anode material, radiation compensation filter, and the like. As the X-ray conditions X1, X2, X3 and X4, appropriate X-ray conditions for the respective irradiation fields or X-ray conditions according to the preference of the examiner are set.

  When the examiner inputs an irradiation field switching instruction via the input unit 25, the image processing switching is performed in conjunction with the irradiation field switching. Specifically, the system control unit 32 reads the correspondence table stored in the storage unit 26. The system control unit 32 sends an image processing switching instruction signal to the image processing unit 22 based on the read correspondence table. The image processing unit 22 switches the image processing to P1, P2, P3 and P4 in accordance with the irradiation fields X1, X2, X3 and X4. The image processing P1, P2, P3 and P4 are stored in advance in the storage unit 26. Note that the image processing P1, P2, P3, and P4 may be changed by the examiner via the input unit 25. The difference between the image processing P1, P2, P3 and P4 is, for example, resolution or contrast. In the image processing P1, P2, P3 and P4, an image processing method appropriate for each irradiation field or an image processing method according to the examiner's preference is set.

  When the irradiation field switching is completed, the system control unit 32 executes X-ray imaging by the examiner inputting an instruction via the input unit 25. In X-ray imaging, the image generation unit 21 generates an X-ray image based on detection signals from a plurality of elements included in the irradiation field range in the X-ray detector 10. Specifically, the X-ray detector 10 reads out the detection signal by limiting the elements included in the irradiation range among the plurality of elements included in the X-ray detector 10. The image generation unit 21 generates an X-ray image by the detection signal read out in a limited manner. The X-ray detector 10 switches the readout range of the detection signal as the irradiation field is switched. A correspondence table of the irradiation field and the readout range of the detection signal is stored in the storage unit 26. That is, when the radiation field sighting is the breast placement portion P1, the image generation unit 21 generates an X-ray image in which the breast placed on the breast placement portion P1 is depicted. When the irradiation field sighting is the first sample placement portion P21, the image generation unit 21 generates an X-ray image in which the sample placed on the first sample placement portion P21 is depicted. When the irradiation field sighting is the second sample placement portion P22, the image generation unit 21 generates an X-ray image in which the sample placed on the second sample placement portion P22 is depicted. The irradiation field aim is defined in the irradiation field switching correspondence table of FIG. 5 and is stored in the storage unit 26. The matrix size of the X-ray image corresponds to the size of the radiation field sighting. As shown in FIG. 3, when the size of the breast placement portion P1 and the size of the sample placement portion P2 are the same, an X-ray image depicting the breast placed on the breast placement portion P1, a first sample placement portion The matrix sizes of the X-ray image in which the sample placed on P21 is drawn and the X-ray image in which the sample placed on the second sample placement portion P22 is drawn are equal. In the case of mammography examination, since the radiation field sighting is the entire detection surface of the X-ray detector 10, the breast X-ray image generated in the mammography examination is larger than the various X-ray images generated in the biopsy examination.

  Hereinafter, a series of operation examples in the present embodiment will be described with reference to FIG. FIG. 11 is a view schematically showing a typical flow of a biopsy inspection according to the present embodiment.

  First, stereo imaging for positioning is performed. Before stereo imaging, the imaging control unit 29 receives a switching instruction from the entire detection surface of the X-ray detector 10 to the breast placement portion P1 input by the examiner via the drive control unit 31 input unit 25. The drive control unit 31 is controlled to switch the radiation field from the entire detection surface of the X-ray detector 10 to the breast placement portion P1. With the switching of the radiation field, the imaging control unit 29 controls the X-ray control unit 30 to change the X-ray condition for the entire detection surface of the X-ray detector 10 to the X-ray condition for the breast placement portion P1. Switch. Further, the system control unit 32 controls the image processing unit 22 according to the irradiation field switching, and switches from the image processing for the breast X-ray image in the mammography examination to the image processing for the breast stereo image in the biopsy examination. In the biopsy test, it is not necessary to set the radiation field for mammography test before starting stereo imaging. The irradiation field may be set to the sample placement portion P2 or may be set to the breast placement portion P1.

  When the breast of the subject is placed on the placement surface 11 and preparation for stereo imaging is completed, the examiner inputs an imaging start instruction via the input unit 25. In response to the instruction input, the system control unit 32 causes the imaging mechanism 2 to perform stereo imaging of the breast (step S1). In step S <b> 1, the system control unit 32 transmits an imaging start instruction to the imaging control unit 29. The imaging control unit 29 controls the X-ray control unit 30 and the drive control unit 31 in accordance with the imaging start instruction, and the breast placed on the breast placement portion P1 at two rotation angles of the X-ray tube support mechanism 4 X-ray. The image generation unit 21 or the reconstruction unit 23 generates a positive breast stereo image based on a detection signal from the X-ray detector 10 at the positive rotation angle, and generates an X-ray detector at the negative rotation angle. 10. Generate a negative breast stereo image based on the detection signal from 10. FIG. 12 is a diagram illustrating an example of a breast stereo image. The display unit 27 displays a breast stereo image I1. The breast stereo image I1 has a positive breast stereo image I11 and a negative breast stereo image I12. Note that normal X-ray imaging at a rotation angle of 0 ° may be performed instead of stereo imaging. However, since the target calcified region has a low contrast, in the present embodiment, in order to increase the imaging accuracy of the target, in step S1, stereo imaging is performed instead of normal X-ray imaging.

  When stereo imaging is performed, the positioning process of the collection needle 16 is subsequently performed. The system control unit 32 first causes the sampling mechanism 13 to perform positioning processing of the collection needle 16 (step S2). In step S2, the image processing unit 22 performs image processing for emphasizing the photographed range of the target TA in the breast stereo image I1. The image processing includes, for example, contrast enhancement processing and resolution improvement processing. The breast stereo image I1 is displayed on the display unit 27. The examiner observes the displayed breast stereo image I1, identifies the position of the target TA inside the breast, and determines the insertion position of the collection needle 16. In the series of operations of the biopsy test, the breast is placed on the placement surface 11 and fixed by the compression plate 12. The examiner inputs an instruction for moving the determined collection needle 16 to the insertion position through the input unit 25. The collection control unit 14 drives the collection drive unit 15 so as to move the collection needle 16 according to the movement instruction via the input unit 25 and moves the collection needle 16 to the insertion position. The collection needle 16 is a hollow needle having an outer diameter of about 3 to 4 mm. The insertion position of the collection needle 16 may be determined by subjecting the mammogram X-ray image I1 to image recognition processing for specifying the position of the target TA.

  When step S2 is performed, the system control unit 32 causes the sampling mechanism 13 to insert the collection needle 16 into the breast (step S3). In step S 3, the system control unit 32 transmits the insertion instruction input by the examiner via the input unit 25 to the collection control unit 14. The collection control unit 14 drives the collection drive unit 15 according to the insertion instruction from the system control unit 32, and causes the sample collection mechanism 13 to insert the collection needle 16 into the breast.

  When step S3 is performed, the system control unit 32 causes the sample collecting mechanism 13 to collect a sample from the breast (step S4). In step S4, the system control unit 32 transmits the collection instruction input by the examiner via the input unit 25 to the collection control unit 14. The collection control unit 14 drives the collection drive unit 15 according to a collection instruction from the system control unit 32, aspirates tissue cells with the collection needle 16 inserted in the breast, and collects a sample. The collected sample is placed on the sample placement portion P2 by the examiner. The X-ray diagnostic apparatus 1 further includes a sample placement unit for placing the collected sample on the sample placement portion P2, and the collected sample is placed on the sample placement portion P2 under the control of the collection control unit 14. It may be placed.

  When step S4 is performed, the system control unit 32 causes the imaging control unit 29 to perform irradiation field switching (step S5). In step S5, the imaging control unit 29 controls the drive control unit 31 in response to the instruction to switch from the breast placement portion P1 to the sample placement portion P2 input by the examiner via the drive control unit 31 input unit 25. The radiation field is switched from the breast placement part P1 to the sample placement part P2. Along with the radiation field switching, the imaging control unit 29 controls the X-ray control unit 30 to switch from the X-ray condition for the breast placement portion P1 to the X-ray condition for the sample placement portion P2. In addition, the system control unit 32 controls the image processing unit 22 to switch the image processing for the breast stereo image to the image processing for the specimen X-ray image in response to the irradiation field switching.

  When step S5 is performed, the system control unit 32 causes the imaging mechanism 2 to perform specimen X-ray imaging (step S6). In step S6, the image generation unit 21 generates a sample X-ray image I2. The display unit 27 displays the sample X-ray image I2. FIG. 13 is a diagram showing an example of the sample X-ray image I2. The display unit 27 may display the breast stereo image I1 and the sample X-ray image I2 side by side. The breast stereo image I1 and the sample X-ray image I2 are placed on the same mounting surface 11 and photographed. Therefore, the system control unit 32 can capture the breast stereo image I1 and the sample X-ray image I2 at the same geometric magnification.

  When step S6 is performed, the system control unit 32 determines the presence or absence of an instruction to end imaging from the input unit 25 (step S7). When the examiner confirms that the target TA is shown in the sample X-ray image I2, the examiner inputs an instruction to end the imaging to the input unit 25. The fact that the target TA appears in the sample X-ray image I2 means that a breast tissue sample has been collected. If it is determined in step S7 that there is an instruction to end the shooting, the series of operations in the present embodiment end. If it is determined in step S7 that there is no instruction to end shooting, the process returns to step S2. In the biopsy test, steps S2 to S7 are repeated because there are many cases where failure of tissue sampling has often occurred. Therefore, the burden on the examiner and the subject is alleviated by being able to repeatedly collect the tissue sample without removing the breast fixed to the mounting surface 11. Further, the ability to perform the collection of tissue samples and the sample X-ray imaging with the same device reduces the burden on the examiner and the subject.

  As described above, according to the X-ray diagnostic apparatus 1 according to the present embodiment, the breast stereo imaging in the biopsy test, the sampling of the tissue sample, and the sample X-ray imaging can be performed by the same apparatus. That is, breast stereo imaging, sampling of a tissue sample, and sample radiography can be performed without removing the breast fixed to the mounting surface 11. Therefore, the burden on the examiner and the subject is reduced by repeatedly performing the sampling of the tissue sample and the sample X-ray imaging without removing the breast fixed to the mounting surface 11. In addition, mammography inspection can be performed with the same apparatus as the biopsy inspection. That is, the image generated in the mammography examination and the image generated in the biopsy examination can be associated as a DICOM image of the same subject. Therefore, it becomes easy to utilize the inspection image of mammography inspection and biopsy inspection, and it becomes easy to use for combination display of a plurality of inspection images and report creation. Thus, the X-ray diagnostic apparatus 1 according to the present embodiment can improve the inspection efficiency of the biopsy inspection.

  Next, various application examples of the present embodiment will be described. In the following description, components having substantially the same functions as those of the present embodiment are denoted by the same reference numerals, and redundant descriptions will be made only when necessary.

(Application example 1)
As in the above embodiment, in the biopsy examination using the X-ray diagnostic apparatus 1, the image generation unit 21 generates a sample X-ray image I2. Further, in the mammography examination, the image generation unit 21 generates a breast X-ray image I3. The display unit 27 according to the application example 1 improves the inspection efficiency of the biopsy inspection by displaying the specimen X-ray image I2 so as to overlap the mammogram X-ray image I3.

  FIG. 14 is a view showing a display example of the breast X-ray image I3 and the sample X-ray image I2 by the display unit 27 according to the application example 1. The display unit 27 displays a mammogram X-ray image I3. The display unit 27 superimposes and displays the sample X-ray image I2 with the predetermined display position of the mammogram X-ray image I3 as the central point based on the instruction of the examiner inputted by the input unit 25. The predetermined display position is changed by an instruction of the examiner via the input unit 25. The predetermined display position is set so that the sample X-ray image I2 does not overlap the breast region in the breast X-ray image I3.

  The display of the sample X-ray image I2 on the breast X-ray image I3 displayed on the display unit 27 will be specifically described. For example, the examiner clicks an icon for switching display / non-display of the sample X-ray image I2 displayed on the display unit 27 by mouse operation, whereby a predetermined mammogram X-ray image I1 displayed on the display unit 27 is displayed. The sample X-ray image I2 is superimposed and displayed on the range. The display unit 27 may also display a mark M1 for indicating the correspondence between the target region TR inside the breast in the breast X-ray image I3 and the sample X-ray image I2. Specifically, the mark M1 is a circle surrounding the target area TR shown in FIG. 14 or a straight line connecting the target area TR and the sample X-ray image I2. For example, upon the drag operation of the mouse for designating the target region TR by the operator, the display unit 27 sets a straight line connecting the circle surrounding the target region TR, the target region TR, and the sample X-ray image I2 to the above image Furthermore, it displays overlapping. Note that the storage unit 26 may store the display screen of the mammogram X-ray image I3, the mark M1 for depicting the correspondence between the target region TR and the sample X-ray image I2, and the mammogram X-ray image I1 as a DICOM image.

  The sample X-ray image I2 may overlap the breast area of the mammogram X-ray image I3, and a portion of the breast area overlapping the sample X-ray image I2 may become invisible. At this time, the examiner can move the display position of the sample X-ray image I2 displayed on the display unit 27 by a drag operation of the mouse. By moving the display position of the sample X-ray image I2, it is possible to make the breast region invisible by the sample X-ray image I2 visible.

  As described above, according to the X-ray diagnostic apparatus 1 according to the application example 1, the display unit 27 superimposes the sample X-ray image I2 generated by the biopsy test on the breast X-ray image I3 generated by the mammography test. It can be displayed. That is, the breast area and the sample area can be interpreted by one image. In addition, the mark M1 can be further superimposed and displayed on the image. The mark can indicate the correspondence between the target region TR in the breast region and the sample X-ray image I2. Therefore, the examiner can easily interpret the breast X-ray image I3 and the sample X-ray image I2. Thus, the X-ray diagnostic apparatus 1 according to the application example 1 can improve the inspection efficiency of the biopsy inspection.

(Application example 2)
The display unit 27 according to the application example 2 displays a breast stereo image and a specimen X-ray image in a layout for determining whether or not a target has been collected in a biopsy test.

  FIG. 15 is a view showing a display example of a breast stereo image and a sample X-ray image by the display unit 27 according to the application example 2. The breast stereo image has a breast stereo image before sampling and a breast stereo image after sampling. As shown in FIG. 15, in the second application example, the display unit 27 determines whether or not the target TA has been collected in the biopsy test, the breast stereo image before sampling, the breast stereo image after sampling, and the specimen. Display X-ray images side by side. As shown in FIG. 15, the display unit 27 displays a breast stereo image before sampling, a breast stereo image after sampling, and a specimen X-ray to assist the examiner to determine whether or not the target TA has been acquired. Display the images arranged vertically in time series. The breast stereo image before sampling has a breast stereo image at the rotation angle on the positive side before sampling and a breast stereo image at the rotation angle on the negative side before sampling. A breast stereo image after sampling has a breast stereo image at a rotation angle on the positive side after sampling and a breast stereo image at a rotation angle on the negative side after sampling. Each image may be displayed in the same size in order to accurately perform the correspondence of the target TA depicted in each image. At this time, the display unit 27 may display the breast stereo image before sample collection, the breast stereo image after sample collection, and the sample X-ray image on one screen by appropriately reducing the size. As a result, the list of breast stereo images before sample collection, breast stereo images after sample collection, and sample X-ray images is improved, and observation of these images is facilitated. The storage unit 26 may store a display screen of a breast stereo image before sample collection, a breast stereo image after sample collection, and a sample X-ray image as a DICOM image.

  In addition, as shown in FIG. 15, the display unit 27 shows the correspondence between the target stereo images drawn in each of the breast stereo image before sampling, the breast stereo image after sampling, and the sample region X-ray image. The mark M2 may be displayed. Both target TAs associated by the mark M2 mean the same. Specifically, the mark M2 is a straight line connecting the target TA in the sample X-ray image and the target TA in the breast stereo image before sampling. The straight line mark is defined by a straight line connecting a start point and an end point designated by the operator via the input unit 25. When the operator designates the start point and the end point, the display unit 27 displays a mark M2 connecting the designated start point and the end point, a breast stereo image before sampling, a breast stereo image after sampling, and a specimen X-ray Display over the image. For example, in FIG. 15, it is assumed that the target TA is depicted in the breast stereo image before sampling, and the target TA is acquired in the biopsy test. In this case, the target TA calculated in the sample X-ray image is depicted, and the target TA is not depicted in the breast stereo image after sampling. That is, it shows that it disappeared before and after sample collection, that is, collection target TA was collected. In such a situation, the examiner instructs via the input unit 25 to associate the target TA depicted in the breast stereo image before sampling and the target TA depicted in the specimen X-ray image. In response to this instruction, the display unit 27 displays the mark M2 that associates the two target TAs. By displaying the mark M2, the display unit 27 can make the observer clearly understand that the plurality of targets TA associated by the mark M2 are the same. The storage unit 26 may store a display screen of a breast stereo image before sampling, a breast stereo image after sampling, and a sample X-ray image on which the mark M2 is drawn as a DICOM image. The breast stereo image after sample collection, the sample X-ray image, and the breast stereo image before sample collection in which the mark M2 is drawn may be associated by the association unit 24 as a DICOM image of the same examination.

  As described above, the display unit 27 according to the application example 2 displays the breast stereo image before sampling, the breast stereo image after sampling, and the specimen X-ray image side by side. Also, the mark M2 can be used to associate the same collection target TA between multiple images. Thus, the display unit according to Application Example 2 can easily determine whether the target TA has been collected. Thus, the X-ray diagnostic apparatus 1 according to the application example 2 can improve the inspection efficiency of the biopsy inspection.

(Application example 3)
The display unit 27 according to the application example 3 is a layout for determining whether or not the target TA is collected in the biopsy test, and displays an image generated by tomosynthesis imaging of a breast and a specimen X-ray image.

  FIG. 16 is a view showing a display example of a breast cross-sectional image and a sample X-ray image by the display unit 27 according to the application example 3. As shown in FIG. 16, in the application example 3, the display unit 27 determines whether or not the target TA has been collected in the biopsy test, and thus the breast sectional image before sampling, the breast sectional image after sampling, and the specimen. Display X-ray images side by side. When there is a mammary gland in the vicinity of the calcified region that is the target TA, the target TA may not be depicted in the X-ray image in stereo imaging and ordinary X-ray imaging. In order to further improve the drawing accuracy of the target TA, it is preferable to display a cross-sectional image generated by tomosynthesis imaging in which the breast is three-dimensionally imaged. Hereinafter, a cross-sectional image generated by reconstructing a breast X-ray image generated by tomosynthesis imaging will be referred to as a breast cross-sectional image.

  When taking a breast tomosynthesis image before sampling, the radiation field is aimed at the breast placement part P1. The examiner instructs start of tomosynthesis imaging via the input unit 25 before sample collection. In response to the start instruction of tomosynthesis imaging, the imaging control unit 29 controls the X-ray control unit 30 and the drive control unit 31 to place the X-ray tube support mechanism 4 on the breast placement portion P1 at a plurality of rotational angles. Radiograph the placed breast. The plurality of rotation angles may be set to, for example, a plurality of rotation angles sandwiching 0 °, such as −φ or more and φ. Specifically, for example, tomosynthesis imaging starts X-ray tube 7 from the position of the rotation angle of -15 ° of X-ray tube support mechanism 4 and continuously moves in the β direction while generating X-rays at constant intervals. Repeat image collection. The X-ray imaging ends at a position where the X-ray tube 7 has a rotation angle of 15 ° of the X-ray tube support mechanism 4. The image generation unit 21 generates a plurality of X-ray images based on detection signals from the X-ray detector 10 at a plurality of rotation angles. The storage unit 26 stores a plurality of breast X-ray images generated by tomosynthesis imaging. The reconstruction unit 23 reconstructs a plurality of breast x-ray images and generates breast volume data. The image processing unit 22 generates a breast cross-sectional image before sampling, which represents a plurality of parallel cross sections, based on breast volume data. A breast cross-sectional image after sample collection is similarly taken.

  As shown in FIG. 16, the display unit 27 displays a plurality of breast cross-sectional images side by side in the vertical direction in correspondence with the tomographic position. Thereby, the examiner can three-dimensionally grasp the target TA depicted in the breast cross-sectional image before the collection of the sample from the cross-sectional image. Therefore, in the case where there is a mammary gland in the vicinity of the calcified region which is the target TA, in particular, the target TA can be easily grasped as compared with the case of observing a breast stereo image and a mammogram.

  As shown in FIG. 16, in order to assist the examiner to determine whether the target TA has been collected, the display unit 27 displays a breast cross-sectional image before sampling, a breast sectional image after sampling, and a specimen X-ray. Display the images side by side along the time series. Note that the display unit 27 may display the image on a single screen by appropriately reducing the breast cross-sectional image before sample collection, the breast cross-sectional image after sample collection, and the sample X-ray image. As a result, the list of breast cross-sectional images before sample collection, breast cross-sectional images after sample collection, and sample X-ray images is improved, and observation of these images becomes easy. The storage unit 26 may store a display screen of a breast cross-sectional image before sample collection, a breast cross-sectional image after sample collection, and a sample X-ray image as a DICOM image.

  In addition, as shown in FIG. 16, the display unit 27 is a mark indicating the correspondence between the target cross-sectional images depicted in each of the breast cross-sectional image before sampling, the breast cross-sectional image after sampling, and the sample X-ray image. M3 may be displayed. Both target TAs associated by the mark M3 mean the same. Specifically, the mark M3 is a straight line connecting the target TA in the sample X-ray image and the target TA in the breast cross-sectional image before sampling. The straight line mark is defined by a straight line connecting a start point and an end point designated by the operator via the input unit 25. When the operator designates the start point and the end point, the display unit 27 marks the M3 connecting the designated start point and the end point, the breast sectional image before sampling, the breast sectional image after sampling, and the specimen X-ray Display over the image. For example, in FIG. 16, it is assumed that the target TA is depicted in the breast cross-sectional image before sampling, and the target TA is collected in the biopsy test. In this case, the target TA acquired in the sample X-ray image is depicted, and the target TA is not depicted in the breast cross-sectional image after sampling. That is, it shows that it disappeared before and after sample collection, that is, collection target TA was collected. Under such circumstances, the examiner instructs via the input unit 25 to associate the target TA depicted in the breast cross-sectional image before sampling with the target TA depicted in the specimen X-ray image. In response to this instruction, the display unit 27 displays a mark that associates the two target TAs. By displaying the mark M3, the display unit 27 can make the observer clearly understand that the plurality of targets TA associated by the mark M3 are the same. The storage unit 26 may store a display screen of a breast cross-sectional image before sampling, a breast cross-sectional image after sampling, and a sample X-ray image on which the mark M3 is drawn as a DICOM image.

  Furthermore, the image processing unit 22 may perform image analysis on the breast cross-sectional image before sampling and the breast cross-sectional image after sampling to determine whether or not the target TA is collected. Specifically, image analysis is realized by pattern recognition processing or the like. The determination result is displayed on the display unit 27. Note that, as shown in FIG. 16, the display unit 27 further supports the determination by the examiner as to whether or not the target TA has been collected by displaying the analysis results side by side on the display screen.

  As described above, the display unit 27 according to the application example 3 displays the breast cross-sectional image before sample collection, the breast cross-sectional image after sample collection, and the sample X-ray image side by side. Thereby, the examiner can three-dimensionally grasp the target TA depicted in the breast cross-sectional image before the collection of the sample from the cross-sectional image. Also, the mark M3 can be used to associate the same collection target TA between multiple images. Thus, the display unit according to the application example 3 can easily determine whether the target TA has been collected. Therefore, the positioning accuracy of the collection needle 16 is improved. Further, image analysis is performed on the breast cross-sectional image before sample collection and the breast cross-sectional image after sample collection to determine whether or not the target TA is collected, and the analysis result can be displayed. Thus, the X-ray diagnostic apparatus 1 according to the application example 3 can improve the inspection efficiency of the biopsy inspection.

(Application example 4)
In the above embodiment, in the biopsy examination using the X-ray diagnostic apparatus 1, the examiner needs to evaluate the radiation dose of the subject in order to perform X-ray imaging a plurality of times. At the time of biopsy inspection, a report on exposure dose is prepared to evaluate the exposure dose. In addition, in the report of the biopsy test, information such as the volume of the collected sample is also important. In the application example 4, the display unit 27 displays the sample X-ray image, the integrated exposure dose under examination, and the information on the volume of the sample in parallel.

  FIG. 17 is a diagram illustrating an example of a biopsy test report according to the application example 4. The image processing unit 22 according to the application example 4 has a dose calculation function and a volume calculation function. In the dose calculation function, the image processing unit 22 is a function of calculating the integrated radiation dose of the subject in the biopsy test. For example, the image processing unit 22 calculates an average breast dose (hereinafter referred to as AGD) and an incident surface dose (hereinafter referred to as ESD). In the volume calculation function, the image processing unit 22 is a function of calculating the sample volume. In FIG. 17, four volumes, Total, Max, Min, and Ave, are displayed as sample volumes. Total indicates the total volume of the collected sample. Max represents the volume of the largest volume sample among the collected samples. Min indicates the volume of the smallest volume sample among the collected samples. Ave indicates the average value of the volume of the collected sample. The storage unit 26 may store the display screen of the biopsy test report of FIG. 17 as a DICOM image.

  As described above, the display unit 27 according to the application example 4 displays the sample X-ray image, the integrated exposure dose under examination, and the information on the volume of the sample, side by side. Thereby, the display unit 27 according to the application example 4 can easily grasp the integrated radiation dose in the biopsy inspection and the sample image and the sample information. Thus, the X-ray diagnostic apparatus 1 according to the application example 4 can improve the inspection efficiency of the biopsy inspection.

(Application example 5)
In the above embodiment, in the biopsy examination using the X-ray diagnostic apparatus 1, it is necessary to reduce the exposure dose to the subject in order to perform X-ray imaging a plurality of times. In the application example 5, the X-ray diagnostic apparatus 1 further includes an X-ray protection mechanism 42 for reducing the exposure dose to the subject. The X-ray protection mechanism 42 reduces the exposure dose to the subject when the radiation field is aimed at the sample mounting portion P2.

  FIG. 18 is a view showing an example of a mounting table installation type X-ray protection mechanism 42 according to the application example 5. As shown in FIG. A mounting table installation type X-ray protection mechanism 42 is installed on the mounting table 9. The X-ray protection mechanism 42 is formed of a heavy metal such as lead for shielding X-rays. The X-ray protection mechanism 42 is designed in shape and size so as to shield X-rays generated by the X-ray tube 7 and irradiated to the subject. Further, the X-ray protection mechanism 42 shields the X-ray which is reflected by the mounting surface 11 or the X-ray detector 10 and is irradiated to the subject. The X-ray protection mechanism 42 is installed so that X-rays do not block the incidence on the sample placement portion P2 and the breast placement portion P1. The X-ray protection mechanism 42 is installed on the mounting table 9 or the sampling mechanism 13. The mounting table installation type X-ray protection mechanism 42 may be detachably fixed to the mounting table 9 or the sampling mechanism 13 with a screw or the like. The X-ray protection mechanism 42 may be installed in the sample collecting mechanism 13 as shown in FIG.

  Thus, the X-ray diagnostic apparatus 1 according to the application example 5 can reduce the exposure dose of the subject in the biopsy test.

  While certain embodiments of the present invention have been described, these embodiments have been presented by way of example only, and are not intended to limit the scope of the invention. These novel embodiments can be implemented in various other forms, and various omissions, substitutions, and modifications can be made without departing from the scope of the invention. These embodiments and modifications thereof are included in the scope and the gist of the invention, and are included in the invention described in the claims and the equivalent scope thereof.

  DESCRIPTION OF SYMBOLS 1 ... X-ray diagnostic apparatus, 2 ... imaging mechanism, 3 ... mounting base support mechanism, 4 ... X-ray tube support mechanism, 5 ... support | pillar, 6 ... axial part, 7 ... X-ray tube, 8 ... high voltage generation part, 9 ... mounting table, 10 ... X-ray detector, 11 ... mounting surface, 12 ... compression plate, 13 ... sampling mechanism, 14 ... collection control unit, 15 ... collection driving unit, 21 ... image generation unit, 22 ... image processing Unit 23 Reconfiguration unit 24 Association unit 25 Input unit 26 Storage unit 27 Display unit 28 Interface unit 29 Imaging control unit 30 X-ray control unit 31 Drive control Unit 32 System control unit 33 Irradiation field limiter 34 X-ray tube support mechanism drive unit 35 Mounting table support mechanism drive unit 41 Opening drive unit 42 X-ray protection mechanism

An X-ray diagnostic apparatus according to the present embodiment includes an X-ray tube generating X-rays, an X-ray detector detecting X-rays generated from the X-ray tube, the X-ray tube, and the X-ray detector provided between the mounting base and a specimen mounting portion which specimens the taken from the subject and the subject mounting portion which the subject is placed is placed, switching is performed by the user depending on the operation, the X-rays generated from the X-ray tube, wherein a first irradiation area corresponding to the subject mounting portion, between the second illumination area corresponding to the specimen mounting portion, selected to anda switching unit for Ru is irradiated switched manner.

Claims (24)

An x-ray tube that generates x-rays,
An X-ray detector for detecting X-rays generated from the X-ray tube;
A mounting surface held between the X-ray tube and the X-ray detector and having a mounting portion for a subject and a mounting portion for a sample collected from the subject;
A mounting table supporting mechanism for supporting the X-ray detector and the mounting surface;
An X-ray tube support mechanism rotatably supporting the X-ray tube about a predetermined rotation axis;
The X-ray tube by controlling the X-ray tube support mechanism and the X-ray tube limiter, wherein the X-ray tube support mechanism and the X-ray tube limiter are configured to limit the opening angle of the X-ray tube. An imaging control unit for selectively switching an irradiation field on the placement surface for X-rays generated from the light source between the placement portion for the subject on the placement surface and the placement portion for the sample When,
X-ray diagnostic device equipped with   The X-ray diagnostic apparatus according to claim 1, wherein the mounting surface has a mounting portion for the subject and a mounting portion for the sample on the same surface.   The imaging control unit controls the angle around the rotation axis of the X-ray tube supported by the X-ray tube support mechanism and the size and shape of the opening of the irradiation field limiter, thereby for the subject. The X-ray diagnostic apparatus according to claim 1, wherein the irradiation field is selectively switched between a mounting portion and a mounting portion for the sample.   The imaging control unit selectively switches the irradiation field between the mounting portion for the subject and the mounting portion for the sample in response to a switching instruction from the examiner. The X-ray diagnostic apparatus according to claim 1. It further comprises a sensing unit that senses the pressure applied to the mounting portion for the sample,
When the sensing unit senses a pressure equal to or higher than a predetermined value, the imaging control unit selectively selects the irradiation field between the placement portion for the subject and the placement portion for the sample. The X-ray diagnostic apparatus according to claim 1, wherein the X-ray diagnostic apparatus switches. It further comprises an X-ray controller that controls X-ray conditions in X-ray imaging,
The imaging control unit controls the X-ray control unit to aim the radiation field at the placement portion for the subject and when aiming at the placement portion for the specimen And switch the X-ray conditions,
The X-ray diagnostic apparatus according to claim 1.   The imaging control unit controls the X-ray tube support mechanism and the radiation field limiter to allow the radiation field in the placement surface of the X-ray generated from the X-ray tube to be the placement surface in the placement surface. The X-ray diagnostic apparatus according to claim 1, wherein the radiation field is switched to the irradiation field including a mounting portion for the subject and a mounting portion for the sample. It further comprises an image generation unit that generates an X-ray image based on an output signal from the X-ray detector,
The imaging control unit performs X-ray imaging on the placement portion for the subject when the radiation field is aimed at the placement portion for the subject, and the radiation field is set for the radiation field. If aiming at the mounting portion for the sample, X-ray imaging is performed on the mounting portion for the sample;
The image generation unit generates an X-ray image of the subject by X-ray imaging targeting the placement portion for the subject, and a sample X by X-ray imaging targeting the placement portion for the sample. Generate line images,
The X-ray diagnostic apparatus according to claim 1.   The image processing unit further includes an image processing unit that switches contents of image processing such that the sample X-ray image is higher in at least one of contrast and resolution of the subject X-ray image and the sample X-ray image. Item 9. An X-ray diagnostic apparatus according to item 8.   The X-ray diagnostic apparatus according to claim 1, further comprising a sampling mechanism for sampling the sample from the subject placed on the placement surface supported by the placement table support mechanism.   The imaging control unit controls the X-ray tube support mechanism to aim at the X-ray tube at two different angles for the subject when the radiation field is aimed at the mounting portion for the subject. The X-ray diagnostic apparatus according to claim 1, wherein stereo radiography for performing radiography is performed.   The X-ray diagnostic apparatus according to claim 8, further comprising an association unit that associates the subject X-ray image and the sample X-ray image as DICOM images of the same subject.   The X-ray diagnostic apparatus according to claim 6, further comprising a dose calculation unit that calculates an integrated exposure dose during X-ray imaging based on the X-ray condition.   The X-ray diagnostic apparatus according to claim 13, further comprising a display unit that displays the integrated radiation dose.   The X-ray diagnostic apparatus according to claim 1, further comprising a volume calculation unit that calculates the volume of the sample.   The X-ray diagnostic apparatus according to claim 15, further comprising a display unit that displays the volume of the sample. An input unit,
Based on the examiner's instruction input by the input unit, the sample for the specimen is placed on a predetermined range of an X-ray image generated by X-ray imaging for the placement portion for the subject. The X-ray diagnostic apparatus according to claim 1, further comprising: a display unit which displays an image obtained by cutting out a sample area from an X-ray image generated by X-ray imaging for the target portion in an overlapping manner.   The X-ray diagnostic apparatus according to claim 17, wherein the predetermined range is set to a pixel range separated from a breast region in the subject X-ray image.   The X-ray diagnostic apparatus according to claim 18, wherein the predetermined range is changed according to an instruction by the examiner input in the input unit.   The X-ray diagnostic apparatus according to claim 11, further comprising a display unit configured to display the plurality of X-ray images generated by the stereo imaging and the sample X-ray image in a predetermined layout. An X-ray control unit and an image processing unit that control X-ray conditions in X-ray imaging;
The mounting table support mechanism, the X-ray tube support mechanism, and a drive control unit for controlling the irradiation field limiter.
The imaging control unit controls the X-ray control unit and the drive control unit to perform tomosynthesis imaging before collecting the sample, and the image generation unit generates a plurality of X-ray images.
The imaging control unit controls the X-ray control unit and the drive control unit to perform tomosynthesis imaging after the sampling, and the image generation unit generates a plurality of X-ray images.
The image processing unit performs image processing on the X-ray image before the sample collection and the X-ray image after the sample collection, and determines whether or not cells to be collected are collected.
The X-ray diagnostic apparatus according to claim 1.   The X-ray protection mechanism according to claim 1, further comprising: an X-ray protection mechanism for shielding X-rays from the X-ray tube to the subject when the radiation field is aimed at the mounting portion for the sample. Line diagnostic equipment.   The mounting portion for the sample comprises a first sample mounting portion and a second sample mounting portion, the first sample mounting portion and the second sample mounting portion being for the subject. The X-ray diagnostic apparatus according to claim 1, provided at a distance from the mounting portion.   The X-ray diagnostic apparatus according to claim 1, wherein the subject is a breast.