JP2018015062A - Freezing preservation container - Google Patents

Abstract

A freezing device that can prevent a display part from falling off from a container body, can be used in fields that require a higher level of cleanliness than before, and can reduce manufacturing costs more than before. Provide storage containers. A cryopreservation container (1) includes a container body (10) filled with contents to be cryopreserved and a display section (20) for displaying information about the contents. The cryopreservation container 1 has a connecting member 30 that mechanically connects the container body 10 and the display section 20 . [Selection drawing] Fig. 1

Description

  The present invention relates to a cryopreservation container for freezing and storing contents.

  Conventionally, for example, plastic that adhesive labels affixed to the outer surface of plastic containers such as blood bags and infusion bags are not easily removed due to the effects of water caused by cryogenic temperature or condensation during cryopreservation Containers are known (see Patent Document 1 below).

  The plastic bag for cryopreservation described in Patent Document 1 is formed by sticking an adhesive label on a fiber sheet thermally welded to the outer surface of the cryopreservation plastic. The fiber sheet is made of plastic fiber or paper using a thermoplastic resin compatible with the material of the cryopreservation plastic bag. The fiber sheet made of paper is obtained by coating one or both sides with a thermoplastic resin that is compatible with the material of the cryopreservation plastic bag.

  In Patent Document 1, since the fiber sheet is chemically bonded to the plastic container, it cannot be easily peeled off in moisture or liquid nitrogen. When the adhesive label is attached to the fiber sheet, the adhesive layer of the adhesive label becomes the fiber sheet. It is described that it can be stuck to the surface of a plastic container without being feared of being easily peeled off in moisture or liquid nitrogen.

Japanese Patent No. 3301074

  The cryopreservation container as described above can be used as a container for stably storing cells for a long period of time, for example, in the field of cell medicine such as regenerative medicine, cell-containing pharmaceuticals, and infertility treatment. However, the conventional plastic bag for cryopreservation needs to thermally weld the fiber sheet to the outer surface of the container. Such a fiber sheet may be a source of dust generation and may not be used in the medical field where high cleanliness is required. In addition, the manufacturing cost may increase due to the material cost and the complexity of the manufacturing process.

  The present invention has been made in view of the above problems, and can prevent the display unit from dropping off such as peeling of a label or the like, and can be used in a field where higher cleanliness is required than before. Another object of the present invention is to provide a cryopreservation container capable of reducing the manufacturing cost as compared with the conventional case.

  In order to achieve the above object, a cryopreservation container of the present invention is a cryopreservation container comprising a container body filled with contents to be cryopreserved, and a display unit for displaying information on the contents. And a connecting member for mechanically connecting the container body and the display unit.

  The connecting member may be a binding band. Moreover, the said container main body may have a through-hole or a notch | incision which penetrates the said binding band.

  Further, the container body may be a cryopreservation bag having a breakable part for forming the through hole or the notch in a peripheral part. In this case, the breakable portion has a lower breaking strength than the peripheral portion.

  The display unit may include a label having a base material layer and an adhesive layer, and a label sticking part to which the label is stuck. In this case, the arithmetic label surface roughness Ra is not more than the thickness of the adhesive layer and not less than 0.04 times the thickness of the adhesive layer, and the ratio of the surface area to the unit flat area is 5 or more. .

  According to the cryopreservation container of the present invention, by having a connecting member that mechanically connects the container main body and the display unit, it is possible to prevent the display unit from falling off the container main body. Therefore, it can be used in a field where the degree is required, and the manufacturing cost can be reduced as compared with the conventional case.

The top view of the cryopreservation container which concerns on Embodiment 1 of this invention. The enlarged view which shows the modification of the through-hole and breakable part shown in FIG. The expanded sectional view of the label of the display part of the cryopreservation container shown in FIG. 1, and a label sticking part. The enlarged plan view of the cryopreservation container which concerns on Embodiment 2 of this invention.

  Hereinafter, embodiments of the cryopreservation container of the present invention will be described in detail with reference to the drawings.

[Embodiment 1]
FIG. 1 is a plan view of a cryopreservation container 1 according to Embodiment 1 of the present invention.

  The cryopreservation container 1 of this embodiment can be used as a container for stably cryopreserving cells and the like for a long period of time in the field of cellular medicine such as regenerative medicine, cell-containing pharmaceuticals, and infertility treatment. The cryopreservation container 1 contains the contents such as cells and is cooled to a temperature of 0 ° C. or lower, more specifically from −150 ° C. to −196 ° C. using liquid nitrogen, a deep freezer, etc. Store in a frozen state.

  The cryopreservation container 1 includes a container body 10 that is filled with contents to be cryopreserved, and a display unit 20 that displays information about the contents, and a connection that mechanically connects the container body 10 and the display unit 20. It is characterized by having a member 30.

  In the cryopreservation container 1 of the present embodiment, the container main body 10 is a bag-like cryopreservation bag whose contents are accommodated between flexible sheet-like substrates. In addition, the container main body 10 is not limited to a cryopreservation bag, For example, a tube-shaped container may be sufficient. The material of the container body 10 is not particularly limited as long as it is suitable for cryopreservation of cells or the like, and for example, a resin material such as polyethylene or ethylene / vinyl acetate copolymer resin can be used.

  The container body 10 includes a storage portion 10a for storing contents such as cells, and a tube 11 and a port 12 for filling the storage portion 10a with the content and for delivering the content from the storage portion 10a. I have. The tube 11 is hermetically sealed by, for example, being fused after the container 10a is filled with the contents, so that the ends are welded. The front end of the port 12 is closed by a rubber-like or film-like closing member 12a, and communicates with the outside by passing a bottle needle through the closing member 12a.

  The container body 10 has a peripheral edge portion 10b in which a flexible sheet-like base material is closed around the accommodating portion 10a. The peripheral edge portion 10 b of the container body 10 has a circular through hole 13 for attaching the connection member 30. The shape of the through hole 13 is not particularly limited as long as the connection member can be attached thereto, and may be, for example, a slit shape, a triangle, a quadrangle, or another polygon. Moreover, the peripheral part 10b of the container main body 10 may have the cyclic | annular breakable part 14 for forming the new through-hole 13 in the peripheral part 10b as needed. The breakable portion 14 formed on the peripheral edge portion 10b of the container body 10 has a lower breaking strength than the portion of the peripheral edge portion 10b excluding the breakable portion 14.

  More specifically, the thickness of the breakable portion 14 formed on the peripheral portion 10b of the container body 10 can be made thinner than the thickness of the peripheral portion 10b where the breakable portion 14 is not formed. Further, the breakable portion 14 may be a remaining portion between perforated discontinuous annular cuts formed in the peripheral edge portion 10b of the container body 10. In this way, the breaking strength of the annular breakable portion 14 formed on the peripheral edge portion 10b of the container body 10 can be made lower than the breaking strength of the portion excluding the breakable portion 14 of the peripheral edge portion 10b.

  FIG. 2 is an enlarged view showing a modification of the through hole 13 and the breakable portion 14 shown in FIG. In the example shown in FIG. 2A, the through-hole 13 has an elongated shape such as a long hole or a slit. Further, as shown in FIG. 2B, the container body 10 may have a cut 13 </ b> A together with the through hole 13 or instead of the through hole 13. In the illustrated example, the cut 13A is a linear cut formed so as to penetrate the peripheral edge portion 10b of the container body 10 in the thickness direction. The cut 13A can be formed in a straight line or a curved line.

  The breakable portion 14 of the modification shown in FIG. 2C is formed in the shape of the through-hole 13 in order to form the elongated through-hole 13 or the slit-like through-hole 13 shown in FIG. It has an elongated annular shape corresponding to. Further, the breakable portion 14A shown in FIG. 2D is formed in a linear shape in order to form a linear cut 13A. The breakable portions 14 and 14A are not limited to the case of perforated discontinuous cuts as shown in the figure, and are linear thin walls provided continuously by thinning a part of the peripheral edge portion 10b. It is also possible to form the part.

  The display unit 20 is a tag for displaying information related to the contents of the cryopreservation container 1. In the cryopreservation container 1 of the present embodiment, the display unit 20 is a rectangular plate-like member, for example, and includes a label 21, a label pasting unit 22 to which the label 21 is pasted, and a through hole 23 for attaching the connecting member 30. And have. The label 21 may be provided with a groove or a notch in order to prevent unauthorized replacement, and may be broken when it is peeled off.

  The display unit 20 may not have the label 21. In this case, information regarding the contents may be printed or stamped directly on the display unit 20, or a tag on which the information is printed or stamped may be fixed to the display unit 20. Moreover, the display part 20 does not need to have the through-hole 23 if the connection member 30 can be connected or fixed. In this case, the display unit 20 and the connection member 30 may be integrally formed by, for example, integral molding or insert molding.

  The connection member 30 is a belt-like member that mechanically connects the container body 10 and the display unit 20. For example, the connecting member 30 is inserted into the through hole 13 of the container body 10 and the through hole 23 of the display unit 20, and one end and the other end in the longitudinal direction are connected and joined in an annular shape. The display unit 20 is mechanically connected.

  In the cryopreservation container 1 of the present embodiment, the connection member 30 is an annular binding band that is inserted into the through hole 23 of the display unit 20 and connected to the display unit 20. As a material of the connection member 30, for example, a resin material similar to that of the container body 10 can be used. As the connection member 30, a binding band manufactured by Heraman Tighton Co., Ltd., Insulok (registered trademark) can be suitably used.

  When the connecting member 30 is a binding band, the connecting member 30 includes a band-shaped band portion 31, a head portion (not shown) provided at one end of the band portion 31, and a tail provided at the other end of the band portion 31. Part (not shown). The band part 31 has serrated serrations on the back surface, and the head part has an opening having claws.

  The connecting member 30 has the band part 31 inserted through the through hole 23 of the display unit 20 and the through hole 13 of the container body 10, and the tail part at the other end of the band part 31 is inserted into the opening of the head part at one end of the band part 31. Is inserted. As a result, the band portion 31 becomes annular, and the claw of the opening portion of the head portion and the serration of the band portion are engaged with each other, and the tail portion is prevented from coming off from the opening portion of the head portion. Therefore, the connection member 30 is an annular connection member 30 that mechanically connects the display unit 20 to the container body 10 by combining one end and the other end of the band unit 31.

  FIG. 3 is an enlarged cross-sectional view of the label 21 and the label pasting part 22 of the display unit 20 of the cryopreservation container 1 shown in FIG.

  The label 21 attached to the display unit 20 of the cryopreservation container 1 includes a base material layer 21a and an adhesive layer 21b. The main material constituting the base material layer 21a of the label 21 is, for example, a resin material such as white polyester, and the main material constituting the adhesive layer 21b is, for example, an acrylic pressure-sensitive adhesive.

  On the surface of the base material layer 21 a of the label 21, information such as identification information of contents to be filled in the storage portion 10 a of the cryopreservation container 1 is printed. An adhesive layer 21 b for attaching the label 21 to the label attaching part 22 of the display unit 20 is provided on the back surface of the base material layer 21 a of the label 21. The label 21 has a thickness of about 30 μm to 100 μm, for example, the base material layer 21a has a thickness of about 20 μm to 90 μm, for example, and the adhesive layer 21b has a thickness of about 10 μm to 80 μm, for example. ing.

  The label affixing portion 22 of the display unit 20 has minute irregularities formed on the surface, the arithmetic average roughness Ra is equal to or less than the thickness t of the adhesive layer 21b of the label 21, and the thickness t of the adhesive layer 21b of the label 21 is 0. It is 04 times or more, and the ratio of the surface area to the unit plane area is 5 or more. The ratio of the surface area to the arithmetic average roughness Ra and the unit flat area of the label applying part 22 can be calculated based on, for example, the surface shape measured using a laser microscope.

  More specifically, in order to calculate the arithmetic average roughness Ra of the label affixing portion 22, for example, using a laser microscope, the label affixing portion 22 includes a plurality of minute convex portions 22 a and concave portions 22 b in a predetermined measurement range. Measure the three-dimensional shape. The predetermined measurement range of the label sticking part 22 can be a 200 μm square range at an arbitrary position of the label sticking part 22, for example. The arithmetic average roughness Ra can be measured according to, for example, JIS B 0601-1994.

  Then, based on the measured three-dimensional shape, a roughness curve at a predetermined reference length along the reference line is obtained to calculate the arithmetic average roughness Ra. For example, it is possible to set the reference length to 200 μm, calculate the arithmetic average roughness Ra along the reference line in three directions, and set the average value as the arithmetic average roughness Ra of the label affixing portion 22. Here, a portion protruding above the average line of the roughness curve can be a convex portion 22a, and a portion recessed below the average line can be a concave portion 22b.

  Moreover, in order to calculate the ratio of the surface area to the unit flat area of the label sticking part 22, the three-dimensional shape of the label sticking part 22 is measured in a measurement area of a predetermined flat area using, for example, a laser microscope. The plane area of the region for measuring the three-dimensional shape can be defined as a unit plane area. Further, based on the measured three-dimensional shape, the surface area of the three-dimensional shape including a plurality of minute convex portions 22a and concave portions 22b is calculated.

  And the ratio of the surface area with respect to the unit flat area of the label sticking part 22 is computable using the calculated surface area of the said three-dimensional shape, and the flat area of the measurement area | region of the said three-dimensional shape, ie, a unit flat area. . That is, the ratio of the surface area to the unit flat area of the label attaching portion 22 can be obtained by (surface area of the label attaching portion 22 in the measurement region) / (plane area of the measurement region). If the unevenness of the label attaching part 22 is small, this ratio is close to 1, and this ratio increases as the unevenness of the label attaching part 22 increases.

  The label sticking part 22 of the display part 20 which has said arithmetic mean roughness Ra and the ratio of the surface area with respect to a unit flat area can be manufactured in the following procedures, for example. First, a forming die having an uneven area for forming the label attaching part 22 is prepared. More specifically, for example, after a blast treatment is performed on a part or the whole of the mold to form irregularities, the irregular surface is formed by plating the irregular surface.

  In the blasting treatment in which sand or metal fine particles collide with the surface of the mold, for example, fine particles of 0.01 μm or more and 1000 μm or less can be suitably used. The arithmetic average roughness Ra of the concavo-convex region tends to be smaller as the particles colliding in the blasting process are smaller or the collision energy is lower, and conversely, the arithmetic mean roughness Ra is larger as the particles are larger or the collision energy is higher. Further, the ratio of the surface area to the unit flat area of the concavo-convex region is smaller as the number of colliding particles is smaller, and conversely is larger as the number of particles is larger.

  Thereby, for example, the arithmetic average roughness Ra is not more than the thickness t of the adhesive layer 21b and not less than 0.04 times the thickness t of the adhesive layer 21b on a part or the whole of the mold, and the surface area per unit plane area A concavo-convex region having a ratio of 5 or more is formed. In addition, as a method of forming the uneven region on the mold, in addition to the blasting process, a chemical etching process, a plasma process, a corona process for etching a workpiece by applying a chemical reaction / corrosion action by a chemical such as an etchant. There are methods such as processing, laser processing, and cutting.

  In addition, by combining a photoresist technique, a pattern-shaped uneven region such as a line shape or a lattice shape can be formed on the mold. Moreover, you may give metal plating, such as chromium, to an uneven | corrugated area | region as needed, in order to improve the intensity | strength of an uneven | corrugated area | region. As the material of the mold, for example, steel, ceramics, glass, or the like can be used.

  Next, the resin material of the display unit 20 is plasticized, the shape of the uneven area of the mold is transferred, and the display unit 20 having the label pasting unit 22 is molded. As described above, the arithmetic label roughness Ra is equal to or less than the thickness t of the adhesive layer 21b and 0.04 times the thickness t of the adhesive layer 21b, and the ratio of the surface area to the unit flat area is 5 or more. Can be formed on the display unit 20.

  Hereinafter, the operation of the cryopreservation container 1 of the present embodiment will be described.

  The cryopreservation container 1 is sealed by filling the container 10a with the contents to be cryopreserved via the tube 11 or the port 12, and fusing the tube 11 or closing the port 12 with the closing member 12a. . Thereafter, the cryopreservation container 1 is cooled from −150 ° C. to −196 ° C. using liquid nitrogen, a deep freezer, or the like, and is stored in a state where the contents are frozen through a predetermined inspection.

  When an adhesive label that displays information on the contents is directly attached to the container main body 10, dew condensation occurs on the surface of the container main body 10 due to the low temperature of the container main body 10. There is a risk of the label peeling off. Moreover, the conventional plastic bag for cryopreservation described in the said patent document 1 needs to heat-seal a fiber sheet to the outer surface of a container. Such a fiber sheet may be a source of dust generation and may not be used in the medical field where high cleanliness is required. In addition, the manufacturing cost may increase due to the material cost and the complexity of the manufacturing process.

  On the other hand, the cryopreservation container 1 of the present embodiment includes a container body 10 that is filled with the contents to be cryopreserved, and a display unit 20 that displays information about the contents, and the container body 10 and the display unit. 20 has a connecting member 30 that mechanically connects the two. The display unit 20 may be connected to the container body 10 via the connection member 30 before freezing and inspection of the cryopreservation container 1, or via the connection member 30 after freezing and inspection of the cryopreservation container 1. And may be connected to the container body 10.

  When the display unit 20 is connected to the container body 10 before freezing and inspection of the cryopreservation container 1, the display unit 20 is cooled together with the container body 10. Here, the display unit 20 is mechanically connected to the container main body 10 by the connection member 30. Therefore, even if condensation occurs on the surface of the container body 10 due to a temperature change of the container body 10, there is no influence on the connection between the container body 10 and the display unit 20.

  Further, when the display unit 20 is connected to the container body 10 after freezing and inspection of the cryopreservation container 1, even if condensation occurs on the surface of the container body 10, the connection member is not affected by the moisture. The display unit 20 can be mechanically connected to the container body 10 by 30. Therefore, according to the cryopreservation container 1 of the present embodiment, it is possible to prevent the display unit 20 from dropping from the container body 10 due to the influence of moisture such as condensation.

  In addition, the cryopreservation container 1 of the present embodiment does not include a fiber sheet in which the container body 10 and the display unit 20 may become a dust generation source, and thus is used in a field that requires a higher degree of cleanliness than before. Is possible. Further, since it is not necessary to use a fiber sheet as in the prior art, the material cost can be reduced, the manufacturing process can be facilitated, and the manufacturing cost can be reduced as compared with the conventional case.

  In the cryopreservation container 1 of the present embodiment, the connection member 30 is a binding band connected to the display unit 20, and the container body 10 has a through hole 13 or a cut 13A through which the connection member 30 that is a binding band is inserted. have. Thereby, the connecting member 30 inserted through the through hole 23 of the display unit 20 and connected to the display unit 20 is inserted into the through hole 13 or the cut 13A of the container body 10 and the one end of the band portion 31 of the connecting member 30 is inserted. The display unit 20 can be mechanically connected to the connection member 30 simply by inserting the tail part through the opening of the head part at the other end of the band part 31. Therefore, it becomes easy to mechanically connect the display unit 20 to the container body 10 via the connection member 30.

  Further, when the connecting member 30 is a binding band, when the connecting member 30 and the display unit 20 are integrally formed, the trouble of inserting the connecting member 30 into the through hole 23 of the display unit 20 can be saved. it can. Therefore, it becomes easier to mechanically connect the display unit 20 to the container body 10 via the connection member 30. Further, when the connection member 30 is a binding band, the container body 10 can be disconnected without breaking any of the through hole 13 or the cut 13A of the container body 10, the through hole 23 of the display unit 20, and the connection member 30. The display unit 20 cannot be removed. Therefore, unauthorized replacement of the display unit 20 with respect to the container body 10 can be prevented.

  Further, in the cryopreservation container 1 of the present embodiment, the container body 10 is cryopreserved having an annular breakable portion 14 or a linear breakable portion 14A for forming the through hole 13 or the cut 13A in the peripheral portion 10b. It is a bag. The breakable portion 14 has a lower breaking strength than the peripheral edge portion 10 b of the container body 10.

  Therefore, when a force is applied to the inner region of the annular breakable portion 14 of the peripheral edge portion 10b of the container body 10 by, for example, pressing with a finger, the stress concentrates on the breakable portion 14, and the breakable portion 14 is annular. The through-hole 13 can be formed in the peripheral part 10b of the container body 10 by breaking. Further, in the case of the linear breakable portion 14A, for example, by pulling the peripheral portion 10b of the container body 10 in a direction intersecting the linear breakable portion 14A, the breakable portion 14A is broken into a linear line. A shaped cut 13A can be newly formed. Therefore, if necessary, the through hole 13 or the cut 13A can be added to the container body 10 and the additional display unit 20 can be mechanically connected to the container body 10 via the new connection member 30.

  In the cryopreservation container 1, the display unit 20 includes a label 21 having a base material layer 21a and an adhesive layer 21b, and a label pasting unit 22 to which the label 21 is pasted. The label affixing portion 22 has an arithmetic average roughness Ra of not more than the thickness t of the adhesive layer 21b and not less than 0.04 times the thickness t of the adhesive layer 21b, and the ratio of the surface area to the unit flat area is 5 or more. is there.

  Thus, the label sticking part 22 of the display part 20 has arithmetic mean roughness Ra of 0.04 times or more of the thickness t of the adhesive layer 21b of the label 21. Therefore, the plurality of minute convex portions 22a and concave portions 22b formed in the label sticking portion 22 have an average height that is 0.04 times or more the thickness t of the adhesive layer 21b.

  Moreover, since the ratio of the surface area with respect to the unit flat area is 5 or more, the label sticking portion 22 has a plurality of minute convex portions 22a and concave portions 22b having the above average height as the ratio of the surface area to the unit flat area. It has a corresponding predetermined density.

  Therefore, when the adhesive layer 21b is adhered to the label attaching part 22 and the label 21 is attached, the plurality of minute convex parts 22a of the label attaching part 22 bite into the adhesive layer 21b, and the adhesive layer 21b becomes plural of the label attaching part 22. Into the minute recess 22b. Thereby, the adhesive layer 21b can be firmly adhered to the label attaching part 22 of the display unit 20, and the change of the state due to the temperature change of the display part 20 and the peeling of the label 21 due to moisture such as dew condensation can be prevented. .

  Moreover, since the label sticking part 22 has arithmetic mean roughness Ra below the thickness t of the adhesion layer 21b of the label 21, the several minute convex part 22a and recessed part which were formed in the label sticking part 22 22b has the average height below the thickness t of the adhesion layer 21b. That is, most of the minute convex portions 22 a formed on the label attaching portion 22 do not penetrate the adhesive layer 21 b of the label 21 and bite into the adhesive layer 21 b without reaching the base material layer 21 a of the label 21.

  Moreover, since the convex part 22a of the label sticking part 22 which penetrates the adhesion layer 21b of the label 21 is few, for example, it bites into the base material layer 21a or is deformed by the base material layer 21a. Thereby, it can prevent that the base material layer 21a of the label 21 bends by the convex part 22a of the label sticking part 22 which reached the base material layer 21a of the label 21, and the adhesive layer 21b of the label 21 and label sticking Adhesiveness with the part 22 can be improved, and the adhesive force of the label 21 can be improved.

  The ratio of the surface area to the arithmetic average roughness Ra of the label attaching part 22 and the unit flat area is measured in two or more measurement ranges that do not overlap in the label attaching part 22, and each measurement range is preferably separated by 1 mm or more. In each measurement range, the arithmetic average roughness Ra of the label affixing portion 22 is not more than the thickness t of the adhesive layer 21b and not less than 0.04 times the thickness t of the adhesive layer 21b, and the ratio of the surface area to the unit flat area Is 5 or more. Thereby, peeling of the label 21 stuck on the label sticking part 22 of the display part 20 can be prevented more reliably.

  The thickness t of the adhesive layer 21b of the label 21 is preferably 10 μm or more. Thereby, not only can the adhesive force of the adhesive layer 21b of the label 21 be sufficiently secured, but the height of the minute convex portions 22a and the concave portions 22b of the label attaching portion 22 can be set to 0.4 μm or more. Therefore, the minute convex portion 22a of the label sticking portion 22 can surely bite into the adhesive layer 21b of the label 21, and the adhesive layer 21b of the label 21 can surely get into the minute concave portion 22b of the label sticking portion 22. The adhesive layer 21b of the label 21 can be firmly adhered to the label attaching part 22.

  The thickness t of the adhesive layer 21b of the label 21 is more preferably 20 μm or more. Thereby, not only the adhesive force of the adhesive layer 21b of the label 21 can be further strengthened, but also the height of the minute convex portions 22a and the concave portions 22b of the label attaching portion 22 can be 0.8 μm or more. Therefore, the minute convex portion 22a of the label sticking portion 22 can be surely bitten by the adhesive layer 21b of the label 21, and the adhesive layer 21b of the label 21 can be surely penetrated by the minute concave portion 22b of the label sticking portion 22. The pressure-sensitive adhesive layer 21b of the label 21 can be firmly adhered by the label pasting portion 22.

  As described above, according to the cryopreservation container 1 of the present embodiment, the display unit 20 can be prevented from falling off from the container body 10, and in a field where a higher degree of cleanliness is required than before. It can be used, and the manufacturing cost can be reduced as compared with the prior art.

[Embodiment 2]
Next, Embodiment 2 of the cryopreservation container of the present invention will be described with reference to FIG. FIG. 4 is an enlarged plan view of a cryopreservation container 1A according to Embodiment 2 of the present invention.

  The cryopreservation container 1A of the present embodiment is mainly different from the cryopreservation container 1 described in the first embodiment in the configuration of the display unit 20A and the configuration of the connection member 30A. Since the other points of the cryopreservation container 1A of the present embodiment are the same as those of the cryopreservation container 1 of the above-described first embodiment, the same portions are denoted by the same reference numerals and description thereof is omitted.

  Similar to the cryopreservation container 1 of the first embodiment, the cryopreservation container 1A of the present embodiment includes a container body 10 that is filled with contents to be cryopreserved, and a display unit 20A that displays information about the contents. It is equipped with. The cryopreservation container 1A has a connecting member 30A that mechanically connects the container body 10 and the display unit 20A.

  In the display unit 20A, for example, an information display medium 24 on which information of contents is printed or engraved between a flexible sheet-like base material similar to the container body 10 is thermally welded to the peripheral portion of the base material. It is enclosed by. As the information display medium 24, for example, a piece of paper or a resin piece on which information such as characters, symbols, and a machine reading code is printed or stamped can be used. Further, the display portion 20A has an attachment portion 25 extending from the peripheral edge portion. The attachment portion 25 is, for example, a portion where the base materials are thermally welded when the information display medium 24 is sealed, similarly to the peripheral portion of the display portion 20A.

  The connecting member 30A is, for example, a metal stapler needle. Both end portions of the connecting member 30A penetrate from the surface side of the peripheral portion 10b of the container main body 10 through the attachment portion 25 of the display portion 20A and the peripheral portion 10b of the container main body 10 to the back side of the peripheral portion 10b of the container main body 10. And is bent along the peripheral edge 10b. Thereby, the connection member 30A mechanically connects the container body 10 and the display unit 20A.

  According to the cryopreservation container 1A of the present embodiment, by having the connection member 30A that mechanically connects the container body 10 and the display unit 20A, dew condensation and the like are performed as in the cryopreservation container 1 of the first embodiment. It is possible to prevent the display unit 20 from dropping from the container main body 10 due to the influence of moisture.

  In addition, the cryopreservation container 1A of the present embodiment does not include a fiber sheet in which the container body 10 and the display unit 20A may become a dust generation source, and thus is used in a field where higher cleanliness is required than before. Is possible. Further, since it is not necessary to use a fiber sheet as in the prior art, the material cost can be reduced, the manufacturing process can be facilitated, and the manufacturing cost can be reduced as compared with the conventional case.

  As described above, according to the cryopreservation container 1A of the present embodiment, it is possible to prevent the display unit 20A from dropping off from the container body 10, and in a field where a higher degree of cleanliness is required than before. It can be used, and the manufacturing cost can be reduced as compared with the prior art.

  The embodiment of the present invention has been described in detail with reference to the drawings, but the specific configuration is not limited to this embodiment, and there are design changes and the like without departing from the gist of the present invention. They are also included in the present invention. For example, although the case where the cryopreservation container is a cryopreservation bag made of a flexible sheet has been described in the above-described embodiment, the cryopreservation container of the present invention is not limited to the cryopreservation bag. The present invention can also be applied to, for example, a tube-type cryopreservation container.

  When the cryopreservation container is a tube type, a through hole for attaching a connecting member such as a binding band can be formed in the lid of the cryopreservation container. Further, when the tube-shaped container body has a constricted portion with a reduced diameter, for example, in the vicinity of the opening, the display unit is fastened to the constricted portion via a connecting member such as a binding band, and the connecting member It is possible to mechanically connect the display unit to the container body via the.

DESCRIPTION OF SYMBOLS 1 Cryopreservation container 1A Cryopreservation container 10 Container main body 13 Through-hole 14 Breakable part 20 Display part 20A Display part 21 Label 21a Base material layer 21b Adhesive layer 22 Label sticking part 30 Connecting member 30A Connecting member t Thickness of adhesive layer

Claims (4)

A cryopreservation container comprising a container body filled with contents to be cryopreserved, and a display unit for displaying information on the contents,
A cryopreservation container comprising a connection member for mechanically connecting the container body and the display unit. The connecting member is a binding band;
The cryopreservation container according to claim 1, wherein the container main body has a through hole or a notch through which the binding band is inserted. The container body is a cryopreservation bag having a breakable part for forming the through-hole or a cut at a peripheral part,
The cryopreservation container according to claim 2, wherein the breakable portion has a breaking strength lower than that of the peripheral portion. The display unit includes a label having a base material layer and an adhesive layer, and a label affixing unit to which the label is affixed,
The label affixing portion has an arithmetic average roughness Ra not more than the thickness of the adhesive layer and not less than 0.04 times the thickness of the adhesive layer, and a ratio of a surface area to a unit flat area is not less than 5. The cryopreservation container according to any one of claims 1 to 3.

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