JP2017169451A - Sleep inducing milk and manufacturing method thereof and feedstuff for dairy cattle - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide such milk that has a strong sleep-inducing action, and thus can contribute to the improvement of insomnia and depression even if it is not special milk, is domestically-produced, and is low-cost milk milked in the usual time zone.SOLUTION: Feeding stuff containing at least any one or more of cheese, egg, and mayonnaise is fed to a dairy cattle, and milk is obtained from the dairy cattle. The egg as described above is a boiled egg, and the boiled egg stored in syrup may be fed in the feeding stuff. More preferably, the feeding stuff further contains garlic (feed garlic) and banana (such as dried powder).SELECTED DRAWING: None

Description

  The present invention relates to milk having a sleep-inducing action, a method for producing the same, and a feed for dairy cows for obtaining such milk.

It is known that milk has a sleep-inducing action. Such an effect is brought about because tryptophan, one of the essential amino acids, is contained in milk. Tryptophan is changed into serotonin in the human body and the like, and it is further changed to melatonin called “sleeping hormone” to induce a person to sleep.
However, since normal milk produced in Japan does not contain a large amount of tryptophan, in order to obtain a sufficient effect, it is necessary to drink a considerable amount or a special foreign product (such as Nordic night milk). It is said that there is. There is also a report that milk squeezed in the daytime has a low content of tryptophan, and that the content increases when squeezed at night.
The sleep inducing action of milk is described in Patent Document 1 below, for example.

JP 2006-169221 A

  In today's society, where people suffer from insomnia and the number of patients with depression are increasing, it is important that general foods have a sleep-inducing effect, and milk has such an effect That is a very favorable fact. However, for the reasons described above, in reality, the effects are not fully enjoyed, or it is necessary to rely on expensive items such as foreign milk and night milk products.

  Therefore, the inventor has a strong sleep-inducing action, and thus improves insomnia and depression, even if it is not such special milk but is domestically produced and low-cost milked in a normal time zone. The present invention has been made for the purpose of providing milk that can contribute.

The milk production method according to the invention is characterized in that a feed containing any one or more of cheese, eggs (egg eggs such as birds, especially chicken eggs), and mayonnaise is fed to dairy cows. Of course, it is also preferable to feed the cows with a feed containing both cheese, eggs and mayonnaise.
Traditionally, cheese, eggs and mayonnaise have not been used as feed for dairy cows. The main reason is that there is no need to feed them to dairy cattle. However, most of the Ministry of Agriculture, Forestry and Fisheries have tried to prevent the occurrence of BSE (Bovine Spongiform Encephalopathy) against ruminants such as cattle and sheep It may be related to the prohibition of animal protein.
However, eggs, cheese made from eggs and milk, and mayonnaise are all rich in tryptophan. Therefore, if these are fed to dairy cows and milked from the dairy cows as described above, milk with a high tryptophan content and thus a strong sleep-inducing action can be easily obtained at a relatively low cost. As a result, milk, which is a common and inexpensive drink, has the effect of preventing or suppressing insomnia and depression, and the present invention greatly contributes to the health promotion of modern people.
Eggs and milk (and their processed foods) are a kind of animal protein, but are not designated as prohibitions on ruminants by the Ministry of Agriculture, Forestry and Fisheries.

As the above-mentioned egg, it is preferable to feed a boiled egg that has been dipped in syrup (stored in a liquid sugar having a high Brix value) and contained in the feed.
Eggs to be fed to dairy cows are included in the feed as boiled eggs, which is more advantageous in terms of ease of handling and cost than adding them to the feed in a raw or baked state. In addition, boiled eggs are often manufactured and used as ingredients for processed foods, and many surplus products are also produced. Therefore, if surplus boiled eggs can be fed to dairy cows, there is a further cost advantage. However, boiled eggs are prone to spoilage and therefore usually need to be stored refrigerated. When trying to feed them to dairy cows as feed, a large refrigerator and considerable power costs are essential.
In that respect, if the boiled egg is stored in syrup as described above and stored in a dairy cow, a large refrigerator and electric power for it are not necessary. This is because boiled eggs that have been pickled in syrup will not rot even if they are not refrigerated.
Therefore, if we supply boiled eggs stored in syrup as described above, surplus boiled eggs can be used without refrigeration costs, and the feed cost for milk and the production cost of the milk are effective. Can be reduced.

For one dairy cow, the above feed should be fed so that the amount of tryptophan is 5000 mg or more per day.
According to the investigations by the inventors, a preferable milk containing tryptophan to such an extent that a sleep-inducing action is brought about at a normal drinking dose can be obtained by feeding the feed and milking the cow.

More preferably, the feed further comprises garlic (garlic for feed) and banana (such as dried and powdered).
Since garlic contains a lot of vitamin B6, the above feed contains a lot of vitamin B6. Vitamin B6 is a substance that improves transferability from tryptophan to serotonin and melatonin. Therefore, when garlic containing a large amount of vitamin B6 (for example, garlic flakes manufactured by Nippon Garlic Co., Ltd.) is fed to the dairy cow along with tryptophan-rich cheese, eggs and mayonnaise, the milk obtained from the dairy cow has a sleep-inducing action. It is considered particularly high.
In addition, banana contains tryptophan and vitamin B6 and is rich in fructose. Fructose turns into glucose in the human body and becomes a brain nutrient and exerts a sedative effect.
Therefore, when garlic and banana are fed to dairy cows together with cheese, eggs and mayonnaise, milk with particularly strong sleep-inducing action can be produced.

For each dairy cow, feed the above feed continuously over the last three days so that the amount of tryptophan is 5000 mg or more per day, the amount of garlic is 100 g or more per day, and the amount of banana is 500 g or more per day. It is particularly preferable to obtain milk from the cow.
As described above, when garlic (vitamin B6) and banana (fructose) are fed to dairy cows together with tryptophan, milk having a high sleep-inducing action can be produced. If each of those salary amounts is as described above, milk having particularly high sleep-inducing action can be produced.

The feed may further contain pineapple meal.
When pineapple koji is given to dairy cows, bromelain enzyme contained in it is activated by cysteine released along with the degradation of dairy cow muscle tissue, and as a result, free amino acid glutamate is produced in the dairy cow's body, and raw milk The content of glutamic acid in it increases. Glutamate becomes gaba (γ-aminobutyric acid), a suppressive neurotransmitter, in the human brain. Therefore, milk obtained from dairy cows fed with pineapple meal along with cheese, eggs, and mayonnaise brings high sleep-inducing action as both melatonin and GABA effects.
In addition, the pineapple cake can use what was obtained by drying the core and outer skin of a pineapple, for example. In that case, the cost is very low. The function of pineapple koji and bromelain enzyme is described in Japanese Patent No. 3341169.

It is preferable that milk having a tryptophan content per 100 g of 250 mg or more can be obtained by the production method described above.
The necessary intake of tryptophan as a standard for improving insomnia is said to be about 500 mg or more per day for Japanese adult males. Since milk is generally drunk about 200cc (200g) at a time using a milk bottle or a normal cup, if the above amount of tryptophan per 100g of milk is included, the above required amount It is filled. Therefore, it is considered that the milk as described above has an effect of improving sleep for most adults. According to the inventors' investigation, it is possible to obtain milk containing the above amount of tryptophan by feeding an appropriate amount of feed containing cheese, eggs and mayonnaise to the dairy cow as described above.

It is also preferable to produce milk having a tryptophan content per 100 g of 250 mg or more and a glycine content per 100 g of 900 mg or more.
As described above, if 100 mg of milk contains 250 mg or more of tryptophan, an effect of improving sleep can be expected. However, glycine, a kind of amino acid, is also said to have an effect of improving sleep and inducing deep sleep. According to the inventors' investigation, milk containing the above amounts of tryptophan and glycine can be obtained from dairy cows by supplying appropriate amounts of feed containing cheese, eggs and mayonnaise to dairy cows as described above. It was. Such milk is considered to have a high sleep improvement effect.

It is preferable to pasteurize raw milk obtained from the dairy cow. Pasteurization refers to sterilization of raw milk at a temperature of about 70 ° C. or lower. For example, sterilization by holding at 65 ° C. for 30 minutes is appropriate.
Melatonin or tryptophan, which are sleep inducers, are not very heat resistant. Therefore, in order to obtain milk having a strong sleep-inducing action by the above production method, it is desirable to pasteurize raw milk squeezed from the dairy cow as described above. If high-temperature sterilization of 120 ° C. or more, which is carried out for many milks, is performed, there is a risk that many of the tryptophan contained in the raw milk obtained as described above will decompose and decrease.
In addition, the production method according to the invention makes it possible to obtain milk having an effect of improving sleep even by milking in a normal time zone in the daytime, not at night. However, in general, milking at night can yield more raw milk containing tryptophan, which is also the case with the present invention.

The milk of the invention is characterized in that the content of tryptophan per 100 g is 250 mg or more. Also very preferred is milk containing 900 mg or more of glycine per 100 g with such an amount of tryptophan.
As described above, if 250 mg or more of tryptophan is contained in 100 g of milk, it is considered that there is an effect of improving insomnia for an adult inoculated with a normal amount of the milk. Since glycine also has the effect of promoting sleep onset and improving sleep quality, the above milk with a high content of tryptophan and glycine has a strong sleep-inducing action, thus contributing to the improvement of insomnia and depression. It is thought to get.

Milk containing tryptophan or further glycine in the above-mentioned amount may be produced by the production method described above.
Since such a production method does not require a particularly difficult technique or work, no special cost is incurred. The milk according to the invention greatly contributes to the health promotion of modern people because it is commercially available as milk that can be ingested on a daily basis, but also has the effect of preventing or suppressing insomnia and depression. It can be said.

The feed for dairy cattle according to the invention is characterized by containing any one or more of cheese, eggs (egg eggs such as birds, especially chicken eggs), and mayonnaise. Of course, those containing both cheese, eggs and mayonnaise are also preferred.
As mentioned above, egg, cheese and mayonnaise, which are mainly made of eggs and milk, contain a lot of tryptophan, so the above feed containing any (or all) of these can be fed to dairy cows. It makes it possible to obtain milk that is rich in tryptophan and therefore has a strong sleep-inducing action.

The above feed for dairy cattle is mixed with a mixed feed containing a concentrated feed such as corn and a fiber feed such as Sudan Hay, cheese, eggs (same as above) and mayonnaise, and the content of tryptophan in 1 kg of dry food feed It is particularly preferably 500 mg or more (up to about 700 mg).
As “a mixed feed containing a concentrated feed such as corn and a fiber feed such as Sudan Hay”, a commercially available general feed for cows can be used. The feed of the invention is obtained by mixing cheese, eggs and mayonnaise in such a general blended feed. By continuously feeding this to the dairy cow, it is possible to keep the dairy cow healthy and grow smoothly, and to obtain milk having a strong sleep-inducing action.
Usually, about 10kg of the above feed per dairy cow is fed as dry matter per day (about 30kg / day / head of dry matter in total with other general dairy cattle feed), so one day per dairy cow This will give more than 5000 mg tryptophan. When each dairy cow is fed such an amount of tryptophan, as described above, preferred milk containing tryptophan to the extent that insomnia can be improved with a normal dose can be obtained.

It is particularly preferable that the dairy cattle feed further includes garlic (garlic garlic) and banana (such as dried and powdered).
As described above, garlic contains a lot of vitamin B6, which is a substance that promotes the transition from tryptophan to serotonin and melatonin. Banana contains a lot of fructose, which is a nutrient of the brain and exerts a sedative effect. Therefore, if garlic and banana are included in the feed together with cheese, eggs and mayonnaise, milk obtained from dairy cows that have consumed the feed has a particularly high sleep-inducing action.

More preferably, pineapple meal is mixed with the above dairy cattle feed.
As described above, the bromelain enzyme contained in pineapple koji has the effect of producing glutamic acid in the body of a dairy cow and increasing the content of glutamic acid in blood and milk. Glutamate is the inhibitory neurotransmitter gab in the human brain, so dairy cows fed a diet containing pineapple koji produce milk with a strong sleep-inducing action as an effect of both melatonin and gabber. Can be obtained. For example, it is advantageous in terms of cost to use a pineapple meal obtained by drying a pineapple core and an outer skin.

  The milk according to the invention, the method for producing the same and the feed for dairy cows are intended to produce a daily beverage having a sleep-inducing action at a low cost. As a result, it has the effect of preventing or suppressing insomnia and depression, and can greatly contribute to the health promotion of modern people.

The inventor conducted a test for the purpose of increasing sleep inducers (tryptophan and glycine) contained in milk.
In other words, the following survey was conducted on how changes in the content of tryptophan and the like in milk occurred when using 36 dairy cows on a farm in Hyogo Prefecture and feeding cheese and the like.

(1) Before the test In September 2015, raw milk was obtained from 36 dairy cows (milking cows) raised with commercially available general formula feeds, mixed with 36 dairy cows, pasteurized, and then in the milk. The amount of tryptophan and glycine was analyzed and measured.
Concentrated feed (60% by weight) such as corn, mylo, barley, wheat, soybean oil cake, cottonseed, bran, rice bran, rapeseed oil cake, Sudanhay, Otsuhei, alfalfa cake, WCS (for feed) Rice is used in combination with fiber feed (40% by weight), and 30 kg per day per day as dry matter (DM) is given according to the general salary. The above 36 dairy cows have an average weight of 650 kg / head and an average milk production of 30 kg / day / head.

(2) Preliminary test (acclimation period)
For one week from December 1st, 2015 to December 7th, a 36-year-old dairy cow was provided with a habituation period for the purpose of getting used to the test feed before this test. During this period, feed prepared by mixing garlic for feed and dried banana was fed to the same blended feed as in the test before (1). The feed garlic was included in the above-described mixed feed so that the amount of garlic for feed was 100 g / day / head and that of dried banana was 500 g / day / head, so that the DM feed amount per head / day was 30 kg.
And on the 7th December of the same year, milk was extracted from all dairy cows, mixed with 36 raw milks and pasteurized, and the amounts of tryptophan and glycine were measured.

(3) Main test For one week from December 8, 2015 to December 14, 2015, the test feed was fed to the 36 dairy cows described above. The test feed used was a mixture of the same blended feed as in (1) above with a mixture of feed garlic and dried banana (ie feed given during the acclimation period in (2) above), cheese, boiled egg ( Boiled chicken eggs) and mayonnaise.
The test feed contains 400 kg of cheese, 300 kg of boiled egg and 1000 kg of mayonnaise in 4450 kg of the total amount of raw materials (total amount including the above-mentioned mixed feed and garlic for feed, dried banana, cheese, boiled egg and mayonnaise) Is mixed in a feed stirrer. Cheese, boiled egg, and mayonnaise contain about 300 mg, 180 mg, and 210 mg of tryptophan per 100 g, respectively, so that 1 kg of test feed contains about 537 mg of tryptophan. . Such test feed was fed to each of the 36 dairy cows at 10 kg per head / day, and the feed given during the acclimation period of (2) above was fed at 20 kg per head / day (total feed amount was (1kg / day 30kg dry matter) The feed garlic and the dried banana were also mixed with the test feed so that the amount per head / day did not change from the period (2).
Therefore, during this test period, each dairy cow was fed about 5370 mg of tryptophan per day per day.
And milk of milk obtained by milking on December 14 of the same year, mixing 36 raw milk and pasteurizing, measured the quantity of tryptophan and glycine.

  Boiled eggs added to the test feed in the main test of (3) above are syrup pickles that have been produced for processed foods in food factories (sucrose brown type with a Brix value of about 75%) Stored in liquid sugar) and used. Stir in syrup and store for a few days in a feed stirrer with liquid sugar and mix. On that basis, when aspirated and deaerated (vacuum) and forcedly anaerobically fermented in a sealed bag, a preferable wet lactic acid fermented feed is completed. When boiled eggs are dipped in syrup and stored, and a mixed feed containing the boiled eggs is produced as described above, it is not necessary to store it in a refrigerator and there is no power cost, so it can be added to the dairy cow feed at low cost.

Tables 1 to 3 show the measurement results (content mg in 100 g of milk) of tryptophan and glycine for the milk obtained in the above periods (1), (2), and (3). Table 1 shows the measurement results for the milk obtained before the test (1), Table 2 shows the milk obtained after the preliminary test (2), and Table 3 shows the milk obtained after the main test (3). Is about.
In Tables 1 to 3, tryptophan is an alkali-hydrolyzed and analyzed by an amino acid automatic analyzer, and glycine is hydrochloric acid-hydrolyzed and analyzed by an amino acid automatic analyzer.

According to Tables 1 to 3, it is confirmed that the contents of tryptophan and glycine are increased after the preliminary test even before the test, but are significantly increased after the test. That is, immediately after this test, tryptophan increased to 280 mg and glycine increased to 910 mg for 100 g of milk.
Tryptophan is thought to have increased on the basis that the tryptophan in the feed given during this study was about 5370 mg per day per cow. As for glycine, it is considered that some substances contained in the fed feed increased due to the biological reaction of dairy cows.

The necessary amount of tryptophan for Japanese adult males to improve insomnia is said to be about 500 mg per day. According to the results in Table 3 above, the milk obtained in this test is 200 cc per day. Ingestion before and after is considered to have an effect of improving sleep in many adults.
Since the milk obtained in this test has a significantly high glycine content as shown in Table 3, it is estimated that the effect of improving sleep by the milk is large.
In addition, although not used in this test etc., it is also meaningful to add a pineapple meal further in the feed which added cheese, a boiled egg, etc. This is because pineapple meal contains a proteolytic enzyme (bromelain enzyme) and increases the content of glutamic acid in raw milk. Glutamate is expected to enhance the sleep-inducing action as a synergistic effect with melatonin because it becomes a suppressor neurotransmitter in the human brain.

Claims (18)

  A method for producing milk, characterized in that a feed containing any one or more of cheese, eggs and mayonnaise is fed to a dairy cow.   The method for producing milk according to claim 1, wherein a feed containing cheese, eggs and mayonnaise is fed to a dairy cow.   The method for producing milk according to claim 1 or 2, wherein a feed containing boiled eggs stored in syrup is fed to dairy cows.   The method for producing milk according to any one of claims 1 to 3, wherein the feed is fed so that the amount of tryptophan per cow is 5000 mg or more per day.   The method for producing milk according to any one of claims 1 to 4, wherein the feed further contains garlic and banana.   The above feed was fed continuously for the last three or more days so that the amount of tryptophan per cow was 5000 mg or more per day, the amount of garlic was 100 g or more per day, and the amount of banana was 500 g or more per day. The milk production method according to claim 5, wherein milk is obtained from a dairy cow.   The method for producing milk according to any one of claims 1 to 6, wherein the feed further comprises pineapple meal.   A milk production method comprising obtaining milk having a tryptophan content per 100 g of 250 mg or more by the production method according to claim 1.   The milk production method according to claim 8, wherein milk having a tryptophan content per 100 g of 250 mg or more and a glycine content per 100 g of 900 mg or more is obtained.   The milk production method according to any one of claims 1 to 9, wherein the raw milk obtained from the dairy cow is pasteurized.   Milk characterized by having a tryptophan content per 100 g of 250 mg or more.   The milk according to claim 11, wherein the content of tryptophan per 100 g is 250 mg or more and the content of glycine per 100 g is 900 mg or more.   Milk produced by the production method according to claim 1, wherein the content of tryptophan per 100 g is 250 mg or more and the content of glycine per 100 g is 900 mg or more.   A feed for dairy cows comprising at least one of cheese, eggs, and mayonnaise.   15. The feed for dairy cows according to claim 14, comprising cheese, eggs and mayonnaise.   The mixed feed containing a concentrated feed such as corn and a fiber feed such as Sudanhay is mixed with cheese, eggs and mayonnaise, and the content of tryptophan in 1 kg is 500 mg or more. 15. Feed for dairy cows according to 15.   The dairy cattle feed according to any one of claims 14 to 16, further comprising garlic and banana.   The dairy cattle feed according to any one of claims 14 to 17, further comprising pineapple meal.