JP2017031123A - Denture stabilizer - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a denture stabilizer that has excellent persistence of soft elasticity and can exhibit cushion effect in an oral cavity for the long term.SOLUTION: A denture stabilizer comprises vinyl acetate resin and propylene glycol fatty acid ester.SELECTED DRAWING: None

Description

  The present invention relates to an adhesion type (cushion type) denture stabilizer having a vinyl acetate resin as a main base. Preferably, the present invention relates to a denture stabilizer that has long-lasting soft elasticity (cushioning property) when used in the oral cavity, that is, excellent in soft elasticity.

  Denture stabilizers are conventionally used by many denture wearers to fix a denture (denture base) at a predetermined position in the oral cavity during non-chewing and chewing. For this reason, as a characteristic of denture stabilizers, in addition to being easy and easy to install and remove (exfoliate) the denture base into the oral cavity, it can be used in the oral cavity after installation into the oral cavity, that is, during use. The adhesiveness and soft elasticity are required to be excellent, and the adhesiveness and soft elasticity are required to last for a long time.

  Among various denture stabilizers, denture stabilizers based on vinyl acetate resin have a paste-like form, expelling the air in the gap between the dentures and gums, like a sucker It is referred to as a “contact type” because of its mechanism of fixing dentures to the gums. Such denture stabilizers have the effect of fixing the dentures so that they do not deviate from the gums, as the main base vinyl acetate resin contracts by absorbing saliva in the mouth and exhibits a cushion shape. The effect of reducing the burden on the gums by expressing soft elasticity (cushioning property) (this effect is called “cushion effect”). For this reason, the close contact type denture stabilizer is also referred to as “cushion type” because of its soft elasticity (cushioning property). Here, “soft elasticity (cushioning property)” means to have both flexibility and elasticity.

  With regard to such close contact type denture stabilizers, many studies have been made in the past with the aim of improving and improving the above-described properties, and various denture stabilizers have been proposed. For example, for denture stabilizers based on a vinyl acetate resin, a low polymerization degree vinyl acetate resin, a medium polymerization degree vinyl acetate resin and a high polymerization degree vinyl acetate resin are used in combination at a specific ratio as the vinyl acetate resin. (Patent Documents 1 and 2) As a vinyl acetate resin, a low polymerization degree vinyl acetate resin and a high polymerization degree vinyl acetate resin are used together in a specific ratio, and ethanol and water are blended in a specific ratio to this to form a paste. (Patent Document 3), a low polymerization degree vinyl acetate resin, a medium polymerization degree vinyl acetate resin and a high polymerization degree vinyl acetate resin are used in combination as a vinyl acetate resin, and a lower alkyl acrylate and a lower alkyl methacrylate. Use of a terpolymer having methacrylic acid trimethylammonium ethyl as a constituent (Patent Documents 4 and 5), and vinyl acetate resin Polypropylene oxide polymer and glycerin acetyl derivative or ethylene glycol acetyl derivative are used in combination (Patent Document 6), and vinyl acetate resin is used in combination with a specific glycerin acetyl derivative instead of ethanol as a plasticizer (Patent Document 6) 7) etc. are proposed.

  In particular, Patent Documents 3, 6 and 7 disclose a technique for improving soft elasticity during use in the oral cavity and its durability, but further improvement is necessary from the viewpoint of sustaining soft elasticity. It is.

JP-A-60-253440 JP 2004-352612 A JP-A-53-148197 JP 2004-350695 A JP 2004-350694 A JP 7-157408 A JP 2014-18488 A

  In view of the above-mentioned problems related to a denture stabilizer called a “contact type” based on a vinyl acetate resin as a main base, the present invention has long-lasting soft elasticity in use in the oral cavity and is long. An object of the present invention is to provide a denture stabilizer that can provide a cushioning effect and has excellent so-called soft elasticity (sustained cushioning effect).

  The inventors of the present invention have been researching day and night with the aim of solving the above problems, and in denture stabilizers based on vinyl acetate resin, by using propylene glycol fatty acid ester in combination with vinyl acetate resin, We found that soft elasticity persists over a long period of time when used in the interior, and confirmed that it was possible to develop and provide a close contact denture stabilizer with excellent cushioning effect.

  The present invention has been completed based on such findings and includes the following embodiments.

(I) Denture stabilizer (I-1 ) A denture stabilizer comprising a vinyl acetate resin and a propylene glycol fatty acid ester.
(I-2) The denture stabilizer described in (I-1), wherein the fatty acid of the propylene glycol fatty acid ester has 8 to 12 carbon atoms.
(I-3) The denture stabilizer described in (I-1) or (I-2), wherein the ratio of propylene glycol fatty acid ester to 100 parts by mass of the vinyl acetate resin is 1 to 100 parts by mass.
(I-4) The denture stabilizer according to any one of (I-1) to (I-3), further comprising ethanol or / and water.
(I-5) The denture stabilizer according to any one of (I-1) to (I-4), wherein the vinyl acetate resin has an average degree of polymerization of 300 to 7000.
(I-6) A vinyl acetate resin having a low degree of polymerization with an average degree of polymerization of 300 to less than 1,000, a medium degree of polymerization of vinyl acetate resin with an average degree of polymerization of 1000 to less than 3000, and a high degree of polymerization with an average degree of polymerization of 3000 to 7,000. The denture stabilizer according to any one of (I-1) to (I-5), which is at least one selected from the group consisting of high-degree vinyl acetate resins.
(I-7) The denture stabilizer described in any one of (I-1) to (I-6), wherein the blending ratio of the vinyl acetate resin is 30 to 80% by mass.
(I-8) The denture stabilizer described in any one of (I-1) to (I-7), which is a denture stabilizer for a complete denture or a partial denture whose plastic denture base is made of plastic.

(II) A method for continuously improving soft elasticity in the oral cavity (II-1) A denture stabilizer based on a vinyl acetate resin, which is a method for continuously improving soft elasticity in the oral cavity, comprising: A method characterized by using propylene glycol fatty acid ester in combination.
(II-2) The method according to (II-1), wherein the propylene glycol fatty acid ester has 8 to 12 carbon atoms in the fatty acid.
(II-3) The method according to (II-1) or (II-2), wherein the ratio of propylene glycol fatty acid ester to 100 parts by mass of vinyl acetate resin is 1 to 100 parts by mass.
(II-4) The method according to any one of (II-1) to (II-3), further comprising adding ethanol or / and water.
(II-5) The method according to any one of (II-1) to (II-4), wherein the vinyl acetate resin has an average degree of polymerization of 300 to 7000.
(II-6) As a vinyl acetate resin, a low polymerization degree vinyl acetate resin having an average polymerization degree of 300 or more and less than 1000, a medium polymerization degree vinyl acetate resin having an average polymerization degree of 1000 or more and less than 3000, and a high average polymerization degree of 3000 or more and 7000 or less. The method according to any one of (II-1) to (II-5), wherein at least one selected from the group consisting of vinyl acetate resins having a degree of polymerization is used.
(I-7) The method according to any one of (II-1) to (II-6), wherein the compounding ratio of the vinyl acetate resin in the denture stabilizer is 30 to 80% by mass.
(II-8) The denture stabilizer is a denture stabilizer for a complete denture or a partial denture whose denture base is made of plastic, and the soft elasticity is soft and elastic between the denture and the gum in the oral cavity. The method according to any one of (II-1) to (II-7).

  Since the denture stabilizer of the present invention preferably has improved durability of soft elasticity in the oral cavity, it exhibits a cushioning effect when the denture and gum are closely fixed in the oral cavity during use for a long period of time. be able to.

  The denture stabilizer of the present invention contains a vinyl acetate resin as a main base and contains at least a propylene glycol fatty acid ester as another component. Hereinafter, each component will be described.

(I) Vinyl acetate resin In the present invention, a vinyl acetate resin having an average degree of polymerization of about 300 to 7000 can be used. The average degree of polymerization is preferably about 450 to 6000, and more preferably the average degree of polymerization is about 450 to 1500.

  In the present invention, one kind of vinyl acetate resin in the range of the average degree of polymerization may be used alone, or two or more kinds of vinyl acetate resins having different degree of polymerization so that the average degree of polymerization is in the above range. It can also be used in combination. In this case, a low polymerization degree vinyl acetate resin having an average polymerization degree of 300 or more and less than 1000, a medium polymerization degree vinyl acetate resin having an average polymerization degree of 1000 or more and less than 3000, and a high polymerization degree vinyl acetate resin having an average polymerization degree of 3000 or more and 7000 or less. Two or more kinds of vinyl acetate resins selected from the group consisting of resins may be used in combination. Here, among the low polymerization degree vinyl acetate resins, the low polymerization degree vinyl acetate resin having an average polymerization degree of 400 to 800 is preferable, and among the intermediate polymerization degree vinyl acetate resins, the average polymerization degree is preferably within a range of 1000 to 2000. It is a vinyl acetate resin having a polymerization degree, and among the vinyl acetate resins having a high polymerization degree, a high polymerization degree vinyl acetate resin having an average polymerization degree of 4000 to 6000 is preferable.

  Although the compounding quantity of the vinyl acetate resin in the denture stabilizer of this invention is not restrict | limited, Usually, it can adjust so that it may become the range of 30-80 mass% of the whole denture stabilizer. Preferably it is 45-75 mass%, More preferably, it is 55-75 mass%. The average degree of polymerization of the vinyl acetate resin can be determined by making a solution of the vinyl acetate resin, obtaining the relative viscosity with water using an Ostwald viscometer, and measuring the average degree of polymerization by calculation from the relative viscosity and the solution concentration. it can.

(2) Propylene glycol fatty acid ester The propylene glycol fatty acid ester means an ester of a fatty acid and propylene glycol or an ester exchange product of an oil and fat and propylene glycol. Preferably, at least one of the two hydroxyl groups of propylene glycol is a monoester or diester having an acyl group esterified with a fatty acid, or a mixture thereof. The combined fatty acid of the propylene glycol fatty acid ester is preferably a saturated fatty acid having 8 to 12 carbon atoms, more preferably a saturated fatty acid having 8, 10 or 12 carbon atoms, and still more preferably a saturated fatty acid having 8 or 12 carbon atoms. Can do. Specifically, propylene glycol monoesters such as propylene glycol monocaprylate, propylene glycol monopelargonate, propylene glycol monocaprate, propylene glycol monolaurate; propylene glycol acetate caprate, propylene glycol laurate And propylene glycol diesters such as acid esters, propylene glycol dicaprylate, propylene glycol dicaprate, propylene glycol dilaurate; and mixtures of two or more of these.

  The propylene glycol fatty acid ester is preferably a monoester. When a mixture of a monoester and a diester is used, the monoester content is preferably 40 to less than 100%, more preferably 60 to less than 100%, and even more preferably 80 to less than 100%.

  In the present invention, the propylene glycol fatty acid ester is preferably a monoester of a saturated fatty acid having 8 to 12 carbon atoms and propylene glycol, and specifically includes propylene glycol monocaprylate and propylene glycol monolaurate. Can do.

  Although the compounding quantity of the propylene glycol fatty acid ester in the denture stabilizer of this invention is not restrict | limited, Usually, it can adjust so that it may become the range of 1-70 mass% of the whole denture stabilizer. Preferably it is 1-40 mass%, More preferably, it is 1-15 mass%. Moreover, as a ratio of the propylene glycol fatty acid ester to 100 parts by mass of the vinyl acetate resin in the denture stabilizer of the present invention, a range of 1 to 100 parts by mass, preferably 1 to 60 parts by mass, more preferably 1 to 30 parts by mass is given. be able to. By using a propylene glycol fatty acid ester in combination with a vinyl acetate resin in this range, the durability of the cushioning effect when using a denture stabilizer in the oral cavity is compared with a denture stabilizer not using a propylene glycol fatty acid ester. Thus, a denture stabilizer that lasts significantly longer and has excellent soft elasticity can be prepared and provided.

(3) Other ingredients
(3-1) Ethanol Although the denture stabilizer of this invention is not restrict | limited, in addition to the said vinyl acetate resin and propylene glycol fatty acid ester, it is preferable that ethanol is further mix | blended. Here, ethanol functions as a solvent for softening the vinyl acetate resin which is the main base of the denture stabilizer of the present invention.

  When ethanol is blended, the blending amount can be usually adjusted to be in the range of 10 to 40% by mass of the whole denture stabilizer. Preferably it is 10-30 mass%, More preferably, it is 10-20 mass%.

  Moreover, although not restrict | limited, when mix | blending ethanol, it is preferable to mix | blend in the ratio which will be 10-40 mass parts with respect to 100 mass parts of vinyl acetate resin mentioned above. More preferably, it is 15-40 mass parts. In addition to the blending of propylene glycol fatty acid ester, by blending ethanol at such a ratio, denture stabilizer to form a cushion shape with excellent soft elasticity and exhibit a good cushioning effect when worn in the oral cavity Can be prepared. Furthermore, the blending ratio of ethanol and vinyl acetate resin is also important for exerting ease of taking out the denture stabilizer from the tube, ease of spreading on the denture, and prevention of adhesion to fingers.

  In addition to the above-mentioned cushion effect, the blending ratio of ethanol to the propylene glycol fatty acid ester described above can also be adjusted as appropriate so that the sustainability of the cushion effect, which is the effect of the present invention, can be obtained better. Although it does not restrict | limit, As a ratio of ethanol with respect to 1 mass part of propylene glycol fatty acid ester, Preferably it sets so that it may become 0.1-30 mass parts. More preferably, it is 0.3-20 mass parts.

(3-2) The denture adhesive of the water present invention, but are not limited to, in addition to the vinyl acetate resin and propylene glycol fatty acid esters, also in addition to the ethanol as necessary, is further compounded water It is preferable. Here, water functions as a softening modifier for the resin, which is the main base of the denture stabilizer of the present invention.

  Although the compounding quantity of water is not restrict | limited, Usually, it can adjust so that it may become the range of 5-25 mass% of the whole denture stabilizer. Preferably it is 7-20 mass%, More preferably, it is 8-15 mass%.

  The blending ratio with ethanol mentioned above is important when the denture stabilizer forms a cushion shape with excellent soft elasticity in the oral cavity and exhibits a cushioning effect. Usually, the ratio of ethanol to 1 part by mass of water Is set to 0.8 to 4.5 parts by mass. Preferably it is 1-3 mass parts. Furthermore, the blending ratio of water and ethanol is also important for exerting the ease of taking out the denture stabilizer from the tube, the ease of spreading on the denture, and the effect of preventing adhesion to the fingers.

(4) Other optional components In addition to the above-mentioned vinyl acetate resin and propylene glycol fatty acid ester, and, if necessary, ethanol or / and water, the denture stabilizer according to the present invention is intended to impart desired properties to the denture stabilizer. Optional ingredients such as plasticizers, emulsifiers, viscosity modifiers, water permeability improvers, release improvers, water-insoluble powders, wetting agents, preservatives, metal soaps, fragrances, colorants, plaque degrading enzymes, etc. Additives can be added as appropriate as long as the effects of the present invention are not impaired.

  Examples of the plasticizer include beeswax, wood wax, carnauba wax, and candelilla wax.

  Examples of the emulsifier include fatty acid esters of glycerin such as glycerin monostearate, fatty acid esters of sorbitan such as sorbitan monostearate, and the like.

  A viscosity modifier adjusts the viscosity of a denture stabilizer, and glycerin, propylene glycol, etc. are used together as needed. In addition, it is preferable that the viscosity of the denture stabilizer of this invention is adjusted so that it may become the range of 1000-5 million centipoise (measurement product temperature: 37 +/- 1 degreeC). More preferably, it is the range of 10,000 to 3000000 centipoise. Particularly for partial dentures, the viscosity is preferably adjusted to be in the range of 100,000 to 800,000 centipoise. More preferably, it is the range of 200000-700000 centipoise. The viscometer is filled with 60 cc of a denture stabilizer in a mayonnaise bottle (Mio-70, manufactured by Koyo Glass Co., Ltd.) and kept at a temperature of 37 ± 1 ° C. for 12 hours or more. DV-II + ", spindle C type, rotation speed 0.5 rpm).

  In addition, it is preferable that the consistency (measured product temperature: 25 degreeC) of the denture stabilizer of this invention is 15 mm or more, More preferably, it is the range of 20-40 mm. More preferably, it is the range of 20-30 mm. The consistency is a physical property value indicating the hardness, softness and fluidity of the paste-like substance. For consistency, 0.5 mL of denture stabilizer is placed on an acrylic plate (80 mm x 80 mm x 5 mm), sandwiched with another acrylic plate (80 mm x 80 mm x 5 mm) from above, and a 1500 g weight is placed on it for 30 seconds. It can be determined by measuring the diameter of the denture stabilizer that has been loaded and spread in a circle, and calculating the average value.

  The water permeability improver has a function of improving the water permeability of the denture stabilizer. Specifically, when the denture stabilizer is closely fixed in the mouth with the denture and gums, the saliva penetrates quickly and the vinyl acetate resin contracts as a result, even though there are few water contact surfaces. Thus, it functions to exert an excellent denture stabilizing effect and cushioning effect. Examples of the water permeability improver include petrolatum such as white petrolatum and yellow petrolatum. Vaseline is also useful as a regulator that suppresses adhesion of the denture stabilizer to the finger when it is spread on the denture base.

  The exfoliation improver facilitates the removal of the denture stabilizer from the contact surface of the denture base after use of the denture, and examples include polybutene, polyisobutylene, calcium carbonate, calcium phosphate, bentonite, silicon dioxide, and terpolymer. .

  Examples of the ternary copolymer include terpolymers having lower alkyl acrylate, lower alkyl methacrylate, and trimethylammonium ethyl methacrylate as constituent components. Here, lower alkyl represents alkyl having 1 to 6 carbon atoms such as methyl, ethyl, propyl and butyl. A particularly preferred terpolymer is composed of ethyl acrylate, methyl methacrylate, and a relatively small amount of trimethylammonium methacrylate. Such a terpolymer is available from EVONIK as “Eudragit ( EUDRAGIT) RS ”is a commercially available random copolymer having a molecular weight of about 150,000 (hereinafter, this commercially available product is referred to as“ commercial terpolymer ”). However, the ternary copolymer used in the present invention is not limited to a commercially available ternary copolymer.

  Examples of the water-insoluble powder include calcium carbonate, calcium phosphate, plastic powder, talc, and silica.

  Examples of the wetting agent include polyethylene glycol, polypropylene glycol, propylene glycol, glycerin, sorbit and the like.

  Examples of the preservative include methyl paraben and ethyl paraben.

  Examples of the metal soap include calcium stearate.

  Examples of the disinfectant include triclosan, cetylpyridinium chloride, isopropylmethylphenol, benzethonium chloride, chlorhexidine and the like.

  Examples of fats and waxes include beeswax, microcrystalline wax, carnauba wax, and candelilla wax. In addition, fragrances, pigments, and the like may be added.

  The denture stabilizer of the present invention is a mixture of vinyl acetate resin and water, mixed so that it is uniformly dispersed, then blended with propylene glycol fatty acid ester and ethanol, and blended with other components as necessary, and then decompressed. It can be prepared in a paste form (cream type, gel type, etc.) by stirring for about 20 to 50 minutes at a temperature of 50 to 60 ° C. while degassing below. Such preparation can be easily carried out by using a stirrer such as a planetary mixer. As described above, the denture stabilizer targeted by the present invention has a paste type such as cream type or gel type.

  The denture stabilizer of the present invention is used for mounting and fixing on the upper jaw or the lower jaw in close contact between the denture and the ridge (gum). The target denture is usually a complete denture. In addition, the material of the denture base made into object has no restriction | limiting in particular, It can apply with respect to a resin floor. Specific examples of the resin floor include a plastic floor.

  Moreover, the denture stabilizer of this invention can be used by the method similar to a normal adhesion type denture stabilizer. For example, it is used by applying and adhering while thinly extending over the entire surface in contact with the upper jaw or lower jaw of the denture base (denture base) excluding moisture. Thus, when a denture with a denture stabilizer attached is placed in the oral cavity and attached to the upper jaw or lower jaw, the denture stabilizer absorbs the moisture of saliva and contracts to form a cushion, and the gums (upper jaw or lower jaw) It is fixed stably by sticking to.

(II) Method for Continuously Improving Soft Elasticity in the Oral of Denture Stabilizer The present invention relates to a method for continuously improving soft elasticity in the oral cavity for a denture stabilizer. More specifically, the present invention relates to a method for continuously improving soft elasticity in the oral cavity with respect to the denture stabilizer containing the vinyl acetate resin described above. This method is characterized in that a propylene glycol fatty acid ester is used in combination with a vinyl acetate resin.

  The vinyl acetate resin and the propylene glycol fatty acid ester blended in combination therewith are as already described in (I), and the description of (I) above is incorporated herein.

  The denture stabilizer targeted for improving the persistence of the soft elasticity in the oral cavity contains a vinyl acetate resin having an average polymerization degree in the range of 300 to 7000 in the proportion of 30 to 80% by mass in the denture stabilizer. It is preferable that Preferably it is 45-75 mass%, More preferably, it is 55-75 mass%.

  As a compounding ratio of the propylene glycol fatty acid ester with respect to the denture stabilizer, a ratio of 1 to 100 parts by mass can be mentioned with respect to 100 parts by mass of the total amount of vinyl acetate resin contained in the denture stabilizer composition. Preferably it is 1-60 mass parts, More preferably, it is 1-30 mass parts. Moreover, as a ratio of the propylene glycol fatty acid ester in the final denture stabilizer (final denture stabilizer) 100% by mass, 1 to 70% by mass, preferably 1 to 40% by mass, more preferably 1 to 15% by mass. Can be mentioned.

Furthermore, ethanol or / and water can be mix | blended with the said denture stabilizer. The mixing ratio of these ethanol and / or water is also as described in (I), and the description of (I) above is incorporated here.
The denture stabilizer thus prepared is a denture stabilizer that does not contain a propylene glycol fatty acid ester, that is, a denture stabilizer that is prepared without using a propylene glycol fatty acid ester in combination with a vinyl acetate resin (control denture stabilizer). Thus, soft elasticity lasts longer in use in the oral cavity, specifically in use in the presence of water at oral temperature (36-38 ° C.). In addition, there is no problem in sustainability even when drinking hot tea or the like (about 45 to 65 ° C.). For this reason, the denture stabilizer prepared using the method of the present invention has an effect that the soft elasticity in the oral cavity is sustained, that is, the cushioning effect is excellent. For this reason, the denture stabilizer prepared using the method of the present invention is excellent in the durability of the cushioning effect when used in the oral cavity. It has the effect that it can be used for a long time while maintaining the effect.

  Hereinafter, based on a test example and an Example, the structure and effect of this invention are demonstrated. However, the present invention is not limited to such test examples and examples. Unless otherwise specified, “%” described below means “mass%”.

Test Example 1 Evaluation of cushioning property (soft elasticity) under oral temperature (1) Preparation of sample and test method Each component described in Tables 1 to 3 is blended in the ratio described in the same table, and each component is uniform. Various denture stabilizers (Examples 1 to 10 and Comparative Examples 1 to 5) were prepared by mixing with stirring using a planetary mixer so as to be dispersed in the mixture.
About these denture stabilizers, the hardness measured with a rubber hardness meter was regarded as soft elasticity (cushioning property), and the sustainability (sustainability of the cushion effect) was evaluated.

  Specifically, each denture stabilizer was placed on an acrylic plate in an amount of 2.5 g, spread evenly with a finger so as to form a circle with a diameter of about 40 mm, and the hardness of the sample surface was measured with a rubber hardness meter (manufactured by ASKER, (Type: C type) (measurement sample temperature: 25 ° C.) (hardness [initial]). Next, the sample was immersed in a 37 ° C. hot water bath for 24 hours, and then quickly removed from the hot water bath, and once returned to room temperature (25 ° C.), the hardness of the sample surface was again measured by a rubber hardness meter (manufactured by ASKER, type : C type) (measurement sample temperature: 25 ° C.) (hardness [after 24 hours]).

  In addition, each hardness measurement is performed about arbitrary 5 places per measurement sample, and the average value is the soft elasticity (cushioning property) under the oral cavity temperature of the sample (Examples 1 to 10 and Comparative Examples 1 to 5). did.

(2) Test results The results are shown in Tables 1-3.

  As shown in Tables 1 to 3, it can be seen that the soft elasticity persists over a long period of time by using a propylene glycol fatty acid ester in combination with the vinyl acetate resin.

Formulation Example Table 4 shows the formulation of the denture stabilizer of the present invention. The denture stabilizer of this invention is prepared by mix | blending each component described in Table 4 in the ratio described in the same table, and mixing while stirring using a planetary mixer so that each component may disperse | distribute uniformly. be able to. In addition, a trace amount pigment can also be mix | blended with the following prescription.

Claims (4)

  A denture stabilizer comprising a vinyl acetate resin and a propylene glycol fatty acid ester.   The denture stabilizer according to claim 1, wherein the fatty acid of propylene glycol fatty acid ester has 8 to 12 carbon atoms.   The denture stabilizer according to claim 1 or 2, wherein the ratio of the propylene glycol fatty acid ester to 100 parts by mass of the vinyl acetate resin is 1 to 100 parts by mass.   A method for continuously improving soft elasticity in a mouth of a denture stabilizer based on a vinyl acetate resin, wherein the vinyl acetate resin and a propylene glycol fatty acid ester are used in combination.