JP2013511990A - 末端置換を含むｓｉＲＮＡ化合物 - Google Patents

末端置換を含むｓｉＲＮＡ化合物 Download PDF

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Publication number: JP2013511990A
Authority: JP; Japan
Prior art keywords: double; nucleic acid; modified; acid molecule; nucleotide
Prior art date: 2009-11-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP2012541211A

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English (en)

Japanese (ja)

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JP2013511990A5 (fr

Inventor

シャロンアヴキン−ナチュム

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Quark Pharmaceuticals Inc

Original Assignee

Quark Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-11-26

Filing date

2010-11-25

Publication date

2013-04-11

2010-11-25 Application filed by Quark Pharmaceuticals Inc filed Critical Quark Pharmaceuticals Inc

2013-04-11 Publication of JP2013511990A publication Critical patent/JP2013511990A/ja

2014-01-09 Publication of JP2013511990A5 publication Critical patent/JP2013511990A5/ja

Status Pending legal-status Critical Current

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US37207210P	2010-08-09	2010-08-09
US61/372,072		2010-08-09
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Publication number	Publication date
US20180030441A1 (en)	2018-02-01
DK2504435T3 (da)	2019-12-09
EP2504435B1 (fr)	2019-11-13
IL218965A0 (en)	2012-07-31
KR20120102630A (ko)	2012-09-18
US20120283309A1 (en)	2012-11-08
EP2504435A1 (fr)	2012-10-03
TW201124160A (en)	2011-07-16
AU2010324658A1 (en)	2012-05-03
US8796239B2 (en)	2014-08-05
CN102597239A (zh)	2012-07-18
US9701960B2 (en)	2017-07-11
WO2011066475A1 (fr)	2011-06-03
US20150152412A1 (en)	2015-06-04
NZ599237A (en)	2014-03-28
US10494631B2 (en)	2019-12-03
ES2759003T3 (es)	2020-05-07
CA2776568A1 (fr)	2011-06-03

Publication	Publication Date	Title
US10494631B2 (en)	2019-12-03	siRNA compounds comprising terminal substitutions
EP2649181B1 (fr)	2016-04-27	Composés oligonucléotidiques à double brin comprenant des modifications de position
CN102770541B (zh)	2016-03-09	包含非核苷酸突出的寡核苷酸化合物
WO2009090639A2 (fr)	2009-07-23	Composés d'arnsi et leurs utilisations
EP3027223A1 (fr)	2016-06-08	Procédés d'utilisation de composés sphingolipide-polyalkylamine-oligonucléotide
EP2855679B1 (fr)	2018-07-18	Oligonucléotides thérapeutiques comprenant des analogues de nucléotide à base de pyrazolotriazine
US10144928B2 (en)	2018-12-04	Double stranded oligonucleotide compounds comprising positional modifications
DK2521783T3 (en)	2017-09-18	OLIGONUCLEOTIDE COMPOUNDS INCLUDING NON-NUCLEOTIDE COVERAGE
HK1189625B (en)	2017-02-17	Double stranded oligonucleotide compounds comprising positional modifications

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