JP2012219057A - Hair tension and stiffness improver - Google Patents

Abstract

（ただし式中、ｎは１又は２であり、Ｒは炭素数９〜２２の直鎖又は分岐鎖の飽和又は不飽和炭化水素基を表す）
【選択図】なし
[Problem] To provide a hair harshness-improving agent having an excellent hair harshness-improving effect and capable of exerting the effect for a long period of time, and a hair cosmetic having a harshness-improving action blended with the harshness-improving agent To do. In addition, the present invention provides a method for improving hair elasticity, which can exhibit the effect for a long period of time using the agent for improving elasticity.
[Means for solving the problem] A hair remedy for hair containing a lactone derivative represented by the following general formula (1) or a hair cosmetic containing the harshness improver is used. It is possible to exert the effect for a long period of time by applying heat treatment after applying the sharpening agent to the hair.
[Chemical 1]

(In the formula, n is 1 or 2, and R represents a linear or branched saturated or unsaturated hydrocarbon group having 9 to 22 carbon atoms)
[Selection figure] None

Description

  The present invention relates to a hair harshness improving agent containing a lactone derivative, a hair cosmetic for harshness improvement containing the harshness improving agent, and a method for improving hair harshness.

  In recent years, it has been known that the physical properties of hair change with aging, and the thickness and bending rigidity of the hair decrease after reaching the peak in their 40s, increasing worries about “there is no elasticity”. In addition, there is a known problem that hair has no elasticity and no volume can be produced on hair (western people often have no elasticity). As a method for improving such hair problems, it has been proposed to replenish components such as keratin, amino acids, and lipids from the outside (Patent Documents 1 and 2). However, since it is washed away by shampooing or the like, it is difficult to maintain the effect for a long time.

  There has also been proposed a method for improving elasticity by allowing a silane compound to penetrate into the hair and polymerize the hair (Patent Document 3). Although it has been reported that the polymerized silane compound is difficult to escape from the hair and the effect of improving the sharpness is maintained, the silane compound has extremely high reactivity, and the stability in the formulation of hair cosmetics is not always sufficient.

  As a use of lactone derivatives in hair cosmetics, it has been reported that δ-lactone derivatives having 7 to 30 carbon atoms can be used as stimulation mitigators (Patent Document 4). Further, as γ-lactone derivatives, it has been reported that a compound having 5 to 15 carbon atoms can be used as an antibacterial agent, and a compound having 4 to 10 carbon atoms can be used as a permanent wave or curl pretreatment agent (Patent Document 5, Patent Document 6). However, it is not known at all about the effect of lactone derivatives to improve hair sharpness.

Japanese Patent Laid-Open No. 11-139941 JP-A-10-152421 JP 2005-320314 A JP2006-0699978 JP 2005-035929 A JP2008-195633

  Provided are a hair harshness improving agent having an excellent hair harshness improving effect and capable of exerting the effect for a long period of time, and a hair cosmetic for harshness improvement containing the harshness improving agent. In addition, the present invention provides a method for improving hair elasticity, which can exhibit the effect for a long period of time using the agent for improving elasticity.

（ただし式中、ｎは１又は２であり、Ｒは炭素数９〜２２の直鎖又は分岐鎖の飽和又は不飽和炭化水素基を表す） As a result of intensive studies to solve the above-mentioned problems, the present inventors have found that the use of a lactone derivative represented by the following general formula (1) can improve hair harshness, thereby completing the present invention. It was. Furthermore, by applying a hair harshness improving agent containing a lactone derivative represented by the following general formula (1) to the hair and applying heat treatment to the hair, the hair harshness is improved and the effect is maintained for a long period of time. Is found.

(In the formula, n is 1 or 2, and R represents a linear or branched saturated or unsaturated hydrocarbon group having 9 to 22 carbon atoms)

  The hair elasticity improving agent of the present invention and the hair cosmetic composition for improving elasticity that contains the elasticity improving agent give an excellent elasticity improving effect to the hair. In addition, by using the method for improving hair elasticity of the present invention, it is possible to give hair elasticity and to exert its effect continuously over a long period of time.

（ただし式中、ｎは１又は２であり、Ｒは炭素数９〜２２の直鎖又は分岐鎖の飽和又は不飽和炭化水素基を表す） The lactone derivative used in the present invention is a compound represented by the following general formula (1).

(In the formula, n is 1 or 2, and R represents a linear or branched saturated or unsaturated hydrocarbon group having 9 to 22 carbon atoms)

  R in the general formula (1) is not particularly limited as long as it is a linear or branched saturated or unsaturated hydrocarbon group having 9 to 22 carbon atoms, but is saturated hydrocarbon from the viewpoint of stability. It is preferably a group. Specifically, nonyl group, decyl group, undecyl group, dodecyl group, tridecyl group, tetradecyl group, pentadecyl group, hexadecyl group, heptadecyl group, octadecyl group, nonadecyl group, eicosyl group, heicosyl group, docosyl group and the like are preferable. Among these, decyl group, undecyl group, dodecyl group, tridecyl group, tetradecyl group, pentadecyl group, hexadecyl group, heptadecyl group, octadecyl group, eicosyl group, heicosyl group in terms of the availability of raw materials and the ease of synthesis A group is more preferable, and a decyl group, a tetradecyl group, and an octadecyl group are most preferable.

  The manufacturing method of the lactone derivative used for this invention is not specifically limited, It can manufacture by a well-known manufacturing method. For example, when n is 1, that is, a γ-lactone derivative, a method of mixing unsaturated fatty acids and a strong acid to isomerize an unsaturated bond and cyclize, or in the presence of a peroxide or an acid catalyst And a method of reacting acrylic acid with alcohol. When n is 2, that is, if it is a δ-lactone derivative, a 5-membered ring ketone compound is oxidized by reacting hydrogen peroxide and acetic acid, or 5-hydroxy contained in natural fats such as meadow foam oil. The method of cyclizing a fatty acid is mentioned. The lactone derivative of the present invention thus obtained may be used after being appropriately purified by extraction, deoxidation, washing with water, recrystallization, adsorption purification, distillation, column purification and the like.

  The hair sharpening agent of the present invention contains the above lactone derivative, but the method of use is not particularly limited as long as it can be uniformly applied to the hair. What is necessary is just to apply | coat to hair, after making it melt | dissolve or disperse | distribute in a solvent etc. and apply | coat to hair, or mix | blend with hair cosmetics. It is preferable that the hair sharpening agent of the present invention is further heat-treated after being applied to the hair. By performing the heat treatment, the effect of improving the elasticity is improved and the effect can be exhibited for a long period of time. When heat-treating the hair, a hair iron, a trowel, a digital permanent, a dryer or the like can be used. Heat treatment conditions are about 1 to 10 times at a set temperature of 60 to 180 ° C. for hair irons and irons, about 1 to 60 minutes at 60 to 120 ° C. for digital perms, and hot air for dryers 30 What is necessary is just to process for about 10 minutes for second.

  The hair sharpening agent of the present invention can be used by being dispersed in an aqueous medium. An aqueous medium means the liquid medium which has water as a main component, and may contain water-soluble inorganic or organic substance as components other than water. When used by dispersing in an aqueous medium, a surfactant may be used for dispersion. As the surfactant, an anionic surfactant, a nonionic surfactant, a cationic surfactant, an amphoteric surfactant, a polymer surfactant and the like which are generally used are described later. Any of these may be used, or two or more of these may be mixed and used. Of these surfactants, it is preferable to mainly use a di-long-chain alkyl quaternary ammonium salt in terms of obtaining a more stable hair cosmetic. Further, it is more preferable in terms of stability to use sterols and / or polyols in combination.

  As said di long-chain alkyl quaternary ammonium salt, it is preferable that carbon number of a long-chain alkyl part is 8-22, Specifically, didecyl dimethyl ammonium chloride, didecyl dimethyl ammonium bromide, dicoco coil Dimethylammonium chloride, dicocoyldimethylammonium bromide, dilauryldimethylammonium chloride, dicetyldimethylammonium chloride, dicetyldimethylammonium bromide, distearyldimethylammonium chloride, distearyldimethylammonium bromide, dioleyldimethylammonium chloride, dibehenyldimethylammonium Chloride, dibehenyldimethylammonium bromide, dialkyldimethylammonium chloride, dialkyldimethylammonium bromide De, Zico coil hydroxyethylmonium methosulfate, dipalmitoyl hydroxyethylmonium methosulfate, etc. distearoylphosphatidylcholine hydroxyethylmonium methosulfate and the like. You may use these in mixture of 2 or more types. Among these, dicocoyl dimethyl ammonium chloride and distearyl dimethyl ammonium chloride are preferable from the viewpoint of availability and stability. The blending amount is not particularly limited, but is usually 0.01 to 20% by weight, more preferably 0.05 to 10% by weight.

  Examples of the sterol include cholesterol, dihydrocholesterol, lanosterol, dihydrolanosterol, and reduced lanolin, lanolin alcohol which are mixtures thereof; β-sitosterol, campesterol, stigmasterol, brassicasterol, and phytosterol which is a mixture thereof. Of sterols. You may use these in mixture of 2 or more types. Among these, cholesterol and phytosterol are preferable from the viewpoints of availability and stability. Although a compounding quantity is not specifically limited, Usually, 0.001 to 5 weight%, More preferably, it is 0.05 to 3 weight%.

  Examples of the polyol include propylene glycol, 1,3-propanediol, dipropylene glycol, glycerin, diglycerin, 1,3-butylene glycol, 1,2-pentanediol, 1,5-pentanediol, isoprene glycol, sorbitol. Hexylene glycol, 1,2-hexanediol, 1,6-hexanediol, maltitol, polyethylene glycol and the like. You may use these in mixture of 2 or more types. Among these, hexylene glycol, propylene glycol, 1,3-propanediol, dipropylene glycol, and 1,3-butylene glycol are preferable from the viewpoints of availability and stability. The blending amount is not particularly limited, but is usually 0.05 to 50% by weight, more preferably 0.1 to 20% by weight.

  When the hair sharpening agent of the present invention is blended in a hair cosmetic, the blending amount is not particularly limited, but is preferably 0.001 to 50% by weight, more preferably 0.005 to 20% by weight.

  The hair sharpening agent of the present invention can be blended in general hair cosmetics, and if necessary, additive components generally blended in hair cosmetics, such as oily bases, moisturizers, and touch improvers. , Surfactant, polymer, thickening / gelling agent, solvent, propellant, antioxidant, reducing agent, oxidizing agent, preservative, antibacterial agent, chelating agent, pH adjuster, acid, alkali, powder, Inorganic salts, vitamins and derivatives thereof, hair growth agents, blood circulation promoters, stimulants, plant / animal / microbe extracts, fragrances, pigments, colorants, dyes, pigments, water and the like can be blended.

  Examples of oily bases include cetanol, myristyl alcohol, oleyl alcohol, lauryl alcohol, cetostearyl alcohol, stearyl alcohol, aralkyl alcohol, behenyl alcohol, jojoba alcohol, chimyl alcohol, ceralkyl alcohol, batyl alcohol, hexyldecanol, isostearyl alcohol, Higher alcohols such as 2-octyldodecanol and dimer diol; aralkyl alcohols and derivatives such as benzyl alcohol; lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, behenic acid, undecylenic acid, 12-hydroxystearic acid, Palmitooleic acid, oleic acid, linoleic acid, linolenic acid, erucic acid, docosahexaenoic acid, eicosapentaenoic acid, isohexa Higher fatty acids such as cannic acid, anteisohenicosanoic acid, long-chain branched fatty acid, dimer acid, hydrogenated dimer acid, and metal soaps such as aluminum salts, calcium salts, magnesium salts, zinc salts, potassium, sodium salts, etc. And nitrogen-containing derivatives such as amides; liquid paraffin (mineral oil), heavy liquid isoparaffin, light liquid isoparaffin, α-olefin oligomer, polyisobutene, hydrogenated polyisobutene, polybutene, squalane, olive-derived squalane, squalene, petrolatum, solid Type hydrocarbons such as candelilla wax, carnauba wax, rice wax, wax, beeswax, montan wax, ozokerite, ceresin, paraffin wax, microcrystalline wax, petrolatum, fisher Tropsch wax, polyethylene wax, waxes such as ethylene / propylene copolymer; palm oil, palm oil, palm kernel oil, safflower oil, olive oil, castor oil, avocado oil, sesame oil, tea oil, evening primrose oil, wheat germ oil, macadamia nut Oil, hazelnut oil, cucumber oil, rosehip oil, meadow foam oil, persic oil, tea tree oil, peppermint oil, corn oil, rapeseed oil, sunflower oil, wheat germ oil, linseed oil, cottonseed oil, soybean oil, peanut oil, rice bran Vegetable oils such as oil, cacao butter, shea fat, hydrogenated coconut oil, hydrogenated castor oil, jojoba oil, hydrogenated jojoba oil; animal properties such as beef tallow, milk fat, horse fat, egg yolk oil, mink oil, turtle oil Fats and oils; animal waxes such as whale wax, lanolin, orange luffy oil; liquid lanolin, reduced lanoli Lanolins such as adsorption purified lanolin, lanolin acetate, liquid lanolin acetate, hydroxy lanolin, polyoxyethylene lanolin, lanolin fatty acid, hard lanolin fatty acid, lanolin alcohol, lanolin alcohol acetate, acetic acid (cetyl lanolyl) ester; lecithin, phosphatidylcholine, Phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, sphingophospholipids such as sphingomyelin, phospholipids such as phosphatidic acid, lysolecithin; hydrogenated soybean phospholipid, partially hydrogenated soybean phospholipid, hydrogenated egg yolk phospholipid, Phospholipid derivatives such as partially hydrogenated egg yolk phospholipids; cholesterol, dihydrocholesterol, lanosterol, dihydrolanosterol, phytoster Sterols such as oleol and cholic acid; sapogenins; saponins; cholesteryl acetate, cholesteryl nonanoate, cholesteryl stearate, cholesteryl isostearate, cholesteryl oleate, di-N-lauroyl-L-glutamate (cholesteryl / behenyl / octyldodecyl) ), N-lauroyl-L-glutamate di (cholesteryl / octyldodecyl), N-lauroyl-L-glutamate di (phytosteryl / behenyl / octyldodecyl), N-lauroyl-L-glutamate di (phytosteryl / octyldodecyl), N Acyl sarcosine alkyl esters such as lauroyl sarcosine isopropyl, cholesteryl 12-hydroxystearate, macadamia nut oil fatty acid cholesteryl, macadamia nut oil fatty acid phyto Sterol esters such as steryl, phytosteryl isostearate, soft lanolin fatty acid cholesteryl, hard lanolin fatty acid cholesteryl, long chain branched fatty acid cholesteryl, long chain α-hydroxy fatty acid cholesteryl; phospholipid / cholesterol complex, phospholipid / phytosterol complex, etc. Lipid complex; octyldodecyl myristate, hexyldecyl myristate, octyldodecyl isostearate, cetyl parmitate, octyldodecyl palmitate, cetyl octanoate, hexyl decyl octanoate, isotridecyl isononanoate, isononyl isononanoate, isononanoate Isotridecyl acid, isodecyl neopentanoate, isotridecyl neopentanoate, isostearyl neopentanoate, octeodecanoate Ludodecyl, oleyl oleate, octyldodecyl oleate, octyldodecyl ricinoleate, lanolin fatty acid octyldodecyl, hexyldecyl dimethyloctanoate, octyldodecyl erucate, isostearic acid hydrogenated castor oil, ethyl oleate, ethyl avocado oil, isopropyl myristate , Isopropyl palmitate, octyl palmitate, isopropyl isostearate, lanolin fatty acid isopropyl, diethyl sebacate, diisopropyl sebacate, dioctyl sebacate, diisopropyl adipate, dibutyl octyl sebacate, diisobutyl adipate, dioctyl succinate, triethyl citrate, etc. Monoalcohol carboxylic acid esters; cetyl lactate, diisostearyl malate, monoisostearyl Oxyacid esters such as acid hydrogenated castor oil; glyceryl trioctanoate, glyceryl trioleate, glyceryl triisostearate, glyceryl diisostearate, glyceryl tri (caprylic / capric), tri (caprylic / capric / myristin) Acid / stearic acid) glyceryl, hydrogenated rosin triglyceride (hydrogenated ester gum), rosin triglyceride (ester gum), glyceryl behenate, trimethylolpropane trioctanoate, trimethylolpropane triisostearate, neopentyl glycol dioctanoate , Neopentyl glycol dicaprate, 2-butyl-2-ethyl-1,3-propanediol dioctanoate, propylene glycol dioleate, pentaerythrtetraoctanoate Chill, hydrogenated rosin pentaerythrityl, triethylhexanoic acid ditrimethylolpropane, (isostearic acid / sebacic acid) ditrimethylolpropane, triethylhexanoic acid pentaerythrityl, (hydroxystearic acid / stearic acid / rosinic acid) dipentaerythrityl, diisostearic acid di Glyceryl, polyglyceryl tetraisostearate, polyglyceryl-10 nonaisostearate, deca (erucic acid / isostearic acid / ricinoleic acid) polyglyceryl-8, (hexyldecanoic acid / sebacic acid) diglyceryl oligoester, glycol distearate (ethylene glycol distearate) , Dineopentanoic acid 3-methyl-1,5-pentanediol, dineopentanoic acid 2,4-diethyl-1,5-pentane Polyhydric alcohol fatty acid esters such as ol; dimer dilinoleate diisopropyl, dimer dilinoleate diisostearyl, dimer dilinoleate di (isostearyl / phytosteryl), dimer dilinoleate (phytosteryl / behenyl), dimer dilinoleate (Phytosteryl / isostearyl / cetyl / stearyl / behenyl), dimer dilinoleic acid dimer dilinoleyl, diisostearic dimer dilinoleyl, dimer dilinoleyl hydrogenated rosin condensate, dimer dilinoleic acid hydrogenated castor oil, hydroxyalkyl die Dimer acid or dimer diol derivative such as merlinoleyl ether; coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), Lauri Acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide (partamide MEA), palmitic acid diethanolamide (partamide DEA), coconut oil Fatty acid alkanolamides such as fatty acid methylethanolamide (cocamidomethyl MEA); dimethicone (dimethylpolysiloxane), highly polymerized dimethicone (highly polymerized dimethylpolysiloxane), cyclomethicone (cyclic dimethylsiloxane, decamethylcyclopentasiloxane), phenyltrimethicone , Diphenyldimethicone, phenyldimethicone, stearoxypropyldimethylamine, (aminoethylaminopropylmethicone / dimethicone) Polymer, dimethiconol, dimethiconol crosspolymer, silicone resin, silicone rubber, amino-modified silicone such as aminopropyl dimethicone and amodimethicone, cation-modified silicone, polyether-modified silicone such as dimethicone copolyol, polyglycerin-modified silicone, sugar-modified silicone, carvone Acid-modified silicone, phosphoric acid-modified silicone, sulfuric acid-modified silicone, alkyl-modified silicone, fatty acid-modified silicone, alkyl ether-modified silicone, amino acid-modified silicone, peptide-modified silicone, fluorine-modified silicone, cation-modified and polyether-modified silicone, amino-modified and poly-modified Ether-modified silicone, alkyl-modified and polyether-modified silicone, polysiloxane-oxyalkylene copolymer Silicones such as body; perfluorodecane, perfluorooctane, fluorine-based oils such as perfluoropolyether may be mentioned as preferred.

  As the humectant / feel improver, glycerin, 1,3-butylene glycol, propylene glycol, 3-methyl-1,3-butanediol, 1,3-propanediol, 2-methyl-1,3-propanediol, Polyols such as trimethylolpropane, pentaerythritol, hexylene glycol, diglycerin, polyglycerin, diethylene glycol, polyethylene glycol, dipropylene glycol, polypropylene glycol, ethylene glycol / propylene glycol copolymer and polymers thereof; diethylene glycol monoethyl ether (Ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol dibutyl ether, etc. (Eicosandioic acid / tetradecandioic acid) water-soluble esters such as polyglyceryl-10 and tetradecandioic acid polyglyceryl-10; sugar alcohols such as sorbitol, xylitol, erythritol, mannitol, maltitol; glucose, fructose, galactose Mannose, threose, xylose, arabinose, fucose, ribose, deoxyribose, maltose, trehalose, lactose, raffinose, gluconic acid, glucuronic acid, cyclodextrins (α-, β-, γ-cyclodextrin, and maltosylation, Modified cyclodextrins such as hydroxyalkylation), β-glucan, chitin, chitosan, heparin and derivatives, pectin, arabinogalactan, dextrin, dextran, glycogen Sugars such as ethyl glucoside, glucosyl ethyl methacrylate polymer or copolymer, and derivatives thereof; hyaluronic acid, sodium hyaluronate; chondroitin sulfate sodium; mucoitin sulfate, caroline sulfate, kerato sulfate, dermatan sulfate; white jellyfish extract, white jellyfish Fucoidan; Tuberose polysaccharide, naturally-occurring polysaccharide; Organic acids such as citric acid, tartaric acid and lactic acid and salts thereof; Urea; 2-pyrrolidone-5-carboxylic acid and salts thereof such as sodium; Betaine (trimethylglycine) , Proline, hydroxyproline, arginine, lysine, serine, glycine, alanine, phenylalanine, tyrosine, β-alanine, threonine, glutamic acid, glutamine, asparagine, aspartic acid, cysteine, cystine, methio , Leucine, isoleucine, valine, tryptophan, histidine, taurine and other amino acids and their salts; collagen, fish-derived collagen, atelocollagen, gelatin, elastin, collagen-degrading peptide, hydrolyzed collagen, hydroxypropylammonium hydrolyzed collagen, elastin Degraded peptide, keratin degrading peptide, hydrolyzed keratin, conchiolin degrading peptide, hydrolyzed conchiolin, silk proteolytic peptide, hydrolyzed silk, lauroyl hydrolyzed silk sodium, soy proteolytic peptide, wheat proteolytic peptide, hydrolyzed wheat protein, casein Protein peptides such as degraded peptides and acylated peptides and their derivatives; palmitoyl oligopeptide, palmitoyl pentapeptide, palmitoyl tetrapep Acylated peptides such as tide; silylated peptides; lactic acid bacteria culture solution, yeast extract, eggshell membrane protein, bovine submandibular gland mucin, hypotaurine, sesame lignan glycoside, glutathione, albumin, whey; choline chloride, phosphorylcholine; Animal and plant extract components such as placenta extract, aerostin, collagen, aloe extract, hamamelis water, loofah water, chamomile extract, licorice extract, comfrey extract, silk extract, Izayoi rose extract, yarrow extract, eucalyptus extract, and melilot extract Preferred are ceramides such as natural ceramides (types 1, 2, 3, 4, 5, 6), hydroxyceramide, pseudoceramide, glycosphingolipid, ceramide, and sugar-ceramide-containing extract.

Preferred examples of the surfactant include an anionic surfactant, a nonionic surfactant, a cationic surfactant, an amphoteric surfactant, and a polymer surfactant. There is no restriction | limiting in particular in HLB of surfactant, It can use from about 1 low thing to about 20 high thing, It is also preferable to combine a low thing and a high thing of HLB. Examples of preferable surfactants include fatty acid salts such as potassium laurate and potassium myristate; alkyl sulfates such as sodium lauryl sulfate, triethanolamine lauryl sulfate, and ammonium lauryl sulfate; laureth Polyoxyethylene alkyl sulfates such as sodium sulfate and laureth sulfate triethanolamine; cocoyl methyl taurine sodium, cocoyl methyl taurine potassium, lauroyl methyl taurine sodium, myristoyl methyl taurine sodium, lauroyl methyl alanine sodium, lauroyl sarcosine sodium, lauroyl sarcosine triethanol Acyl N-methyl amino acid salts such as amines and sodium methylalanine lauroylglutamate; Cocoyl Glue Acyl amino acid salts such as sodium minate, triethanolamine cocoyl glutamate, sodium lauroyl glutamate, sodium myristoyl glutamate, sodium stearoyl glutamate, ditriethanolamine palmitoyl aspartate, cocoylalanine triethanolamine; polyoxyethylene alkyl ethers such as sodium laureth acetate Acetic acid salt; Succinic acid ester salt such as sodium lauroyl monoethanolamide succinate; Fatty acid alkanolamide ether carboxylate; Acyl lactate; Polyoxyethylene fatty amine sulfate; Fatty acid alkanolamide sulfate; Hardened coconut oil fatty acid sodium glyceryl sulfate Fatty acid glyceride sulfate such as alkylbenzene polyoxyethylene sulfate; α-olefin Olefin sulfonates such as sodium sulfonate; alkylsulfosuccinates such as disodium lauryl sulfosuccinate and dioctyl sodium sulfosuccinate; disodium laureth sulfosuccinate, monolauroyl monoethanolamide polyoxyethylene sodium sulfosuccinate, lauryl polypropylene glycol sulfosuccinic acid Alkyl ether sulfosuccinates such as sodium; alkylbenzene sulfonates such as sodium tetradecylbenzenesulfonate and tetraethanolamine tetraethanol; alkylnaphthalenesulfonates; alkanesulfonates; α-sulfo fatty acid methyl ester salts; Acyl isethionate; alkyl glycidyl ether sulfonate; alkyl sulfoacetate; laurethrin Alkyl ether phosphates such as sodium, sodium dilaureth phosphate, sodium trilaureth phosphate, sodium monooles phosphate; alkyl phosphate salts such as potassium lauryl phosphate; sodium caseinate; alkyl aryl ether phosphate; fatty acid amide ether phosphorus Phospholipids such as phosphatidylglycerol, phosphatidylinositol, and phosphatidic acid; silicone anionic surfactants such as carboxylic acid-modified silicone, phosphate-modified silicone, and sulfate-modified silicone; and nonionic surfactants, laureth (Polyoxyethylene lauryl ether), ceteth (polyoxyethylene cetyl ether), steareth (polyoxyethylene stearyl ether), behenez (polyoxyethylene) Nbehenyl ethers), isosteares (polyoxyethylene isostearyl ethers), octyldecesses (polyoxyethylene octyldodecyl ethers) and other polyoxyethylene alkyl ethers with various polyoxyethylene addition numbers; polyoxyethylene alkylphenyl ethers; Polyoxyethylene hydrogenated castor oil, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil monoisostearate, polyoxyethylene hydrogenated castor oil triisostearate, polyoxyethylene hydrogenated castor oil monopyroglutamic acid monoisostearate diester, poly Castor oil such as oxyethylene hydrogenated castor oil maleic acid and hydrogenated castor oil derivatives; polyoxyethylene phytosterol; polyoxyethylene cholesterol; polyoxy Polyoxyethylene lanolin; polyoxyethylene reduced lanolin; polyoxyethylene polyoxypropylene cetyl ether, polyoxyethylene polyoxypropylene 2-decyltetradecyl ether, polyoxyethylene polyoxypropylene monobutyl ether, polyoxyethylene lanolin; Oxyethylene / polyoxypropylene hydrogenated lanolin, polyoxyethylene / polyoxypropylene alkyl ethers such as polyoxyethylene / polyoxypropylene glycerin ether; polyoxyethylene / polyoxypropylene glycol; (poly) such as PPG-9 diglyceryl Glycerin polyoxypropylene glycol; glyceryl stearate, glyceryl isostearate, glyceryl palmitate, myristate group Glyceryl fatty acid partial esters such as ceryl, glyceryl oleate, glyceryl coconut fatty acid, mono-cotton oil fatty acid glycerin, glyceryl monoerucate, glyceryl sesquioleate, α, α'-oleic acid pyroglutamate glycerin, monostearate glycerin malate Polyglyceryl stearate-2, 3, 4, 5, 6, 8, 10, polyglyceryl distearate-6, 10, polyglyceryl tristearate, polyglyceryl decastearate-10, polyglyceryl isostearate -2, 3, 4, 5, 6, 8, 10, diglycostyl diisostearate (diglyceryl diisostearate), 3, 10, polyglyceryl-2 triisostearate, polyglyceryl tetraisostearate Ril-2, polyglyceryl-10 decaisostearate, polyglyceryl-2 oleate, 3,4, 5,6, 8,8, dioleate polyglyceryl-6, trioleate polyglyceryl-2, dekaoleic acid Polyglyceryl fatty acid esters such as polyglyceryl-10; ethylene glycol monofatty acid esters such as ethylene glycol monostearate; propylene glycol monofatty acid esters such as propylene glycol monostearate; pentaerythritol partial fatty acid esters; sorbitol partial fatty acid esters; maltitol moieties Fatty acid ester; maltitol ether; sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monos Sorbitan fatty acid esters such as allate, sorbitan sesquioleate, sorbitan trioleate, diglycerol sorbitan penta-2-ethylhexylate, diglycerol sorbitan tetra-2-ethylhexylate; sucrose fatty acid ester, methyl glucoside fatty acid ester, trehalose undecylenate, etc. Partial derivatives of sugar derivatives; alkyl glucosides such as caprylyl glucoside; alkyl polyglycosides; lanolin alcohols; reduced lanolin; polyoxyethylene distearate, polyethylene glycol diisostearate, polyoxyethylene monooleate, polyoxyethylene di- Polyoxyethylene fatty acid mono- and diesters such as oleate; polyoxyethylene propylene glycol fatty acid ester; polyoxyethylene Polyoxyethylene glycerin fatty acid esters such as polyoxyethylene monooleate such as polyglycerin monostearate, polyoxyethylene glycerin monoisostearate, polyoxyethylene glycerin triisostearate; polyoxyethylene sorbitan monooleate, polyoxy Polyoxyethylene sorbitan fatty acid esters such as ethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan tetraoleate; polyoxyethylene sorbitol monolaurate, polyoxyethylene sorbitol monooleate, polyoxyethylene sorbitol penta Polyoxyethylene sorbitol fatty acid esters such as oleate and polyoxyethylene sorbitol monostearate Polyoxyethylene methyl glucoside fatty acid ester; Polyoxyethylene alkyl ether fatty acid ester; Polyoxyethylene animal and vegetable oils such as polyoxyethylene sorbitol beeswax; Alkyl such as isostearyl glyceryl ether, chimyl alcohol, ceralkyl alcohol, batyl alcohol Glyceryl ethers; polyhydric alcohol alkyl ethers; polyoxyethylene alkylamines; tetrapolyoxyethylene / tetrapolyoxypropylene-ethylenediamine condensates; natural surfactants such as saponins and sophorolipids; polyoxyethylene fatty acid amides; coconut oil Fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (laura) De MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide (partamide MEA), palmitic acid diethanolamide (partamide DEA), palm oil fatty acid methyl ethanolamide (cocamidomethyl) Fatty acid alkanolamides such as MEA); alkyldimethylamine oxides such as lauramine oxide, cocamamine oxide, stearamine oxide, and behenamine oxide; alkylethoxydimethylamine oxide; polyoxyethylene alkyl mercaptan; poly such as dimethicone copolyol Silicone such as ether-modified silicone, polysiloxane-oxyalkylene copolymer, polyglycerin-modified silicone, sugar-modified silicone Nonionic surfactants, etc .; for cationic surfactants, alkyltrimethylammonium chlorides such as behentrimonium chloride, steartrimonium chloride, cetrimonium chloride, lauryltrimonium chloride; alkyls such as stearyltrimonium bromide Trialkylammonium bromide; dialkyldimethylammonium chloride such as distearyldimonium chloride and dicocodimonium chloride; fatty acid amidoamines and salts thereof such as stearamidepropyldimethylamine and stearamideethyldiethylamine; alkyl ether amines such as stearoxypropyldimethylamine; Salt or quaternary salt thereof; ethyl sulfate long chain branched fatty acid (12-31) aminopropylethyldimethylammonium, ethyl lanolin sulfate Fatty acid amide-type quaternary ammonium salts such as aminopropylethyldimethylammonium fatty acid; polyoxyethylene alkylamine and its salts or quaternary salts; alkylamine salts; fatty acid amidoguanidinium salts; alkyl etheraminemonium salts; Benzalkonium salt; Pyridinium salt such as cetylpyridinium chloride; Imidazolinium salt; Alkylisoquinolinium salt; Dialkyl morpholinium salt; Polyamine fatty acid derivatives; Aminopropyl dimethicone and amodimethicone Silicone-based cationic surfactants such as amino-modified silicone, cation-modified silicone, cation-modified and polyether-modified silicone, amino-modified and polyether-modified silicone;
In amphoteric surfactants, N-alkyl-N, N-dimethylamino acid betaines such as lauryl betaine (lauryldimethylaminoacetic acid betaine); fatty acid amide alkyl-N, N-dimethylamino acids such as cocamidopropyl betaine and lauramidopropyl betaine Betaines; imidazoline-type betaines such as sodium cocoamphoacetate and sodium lauroamphoacetate; alkylsulfobetaines such as alkyldimethyltaurine; sulfate-type betaines such as alkyldimethylaminoethanol sulfate; phosphate-type betaines such as alkyldimethylaminoethanol phosphate; Sphingophospholipids such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, sphingomyelin, lysolecithin, hydrogenated soybean phospholipid, partially hydrogenated Phospholipids such as soybean phospholipid, hydrogenated egg yolk phospholipid, partially hydrogenated egg yolk phospholipid, and hydroxylated lecithin; silicone-based amphoteric surfactants; polymer surfactants such as polyvinyl alcohol, sodium alginate, starch derivatives, Preferred are tragacanth gum, acrylic acid / alkyl methacrylate copolymer; and various silicone surfactants.

  Polymers, thickeners and gelling agents include guar gum, locust bean gum, queens seed, carrageenan, galactan, arabic gum, tara gum, tamarind, far selelain, karaya gum, troarooi, cara gum, tragacanth gum, pectin, pectic acid and sodium Salt such as salt, salt such as alginic acid and sodium salt, mannan; starch such as rice, corn, potato, wheat; xanthan gum, dextran, succinoglucan, curdlan, hyaluronic acid and its salt, xanthan gum, pullulan, gellan gum, chitin , Chitosan, agar, gypsum extract, chondroitin sulfate, casein, collagen, gelatin, albumin; methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropi Cellulose, carboxymethylcellulose and salts thereof such as sodium, methylhydroxypropylcellulose, cellulose sodium sulfate, cellulose dialkyldimethylammonium sulfate, crystalline cellulose, cellulose such as cellulose powder and derivatives thereof; soluble starch, carboxymethyl starch, methylhydroxypropyl starch, Starch-based polymers such as methyl starch, starch derivatives such as hydroxypropyltrimonium chloride, octenyl succinate corn starch and aluminum; alginic acid derivatives such as sodium alginate, propylene glycol alginate; Vinyl pydridone-vinyl alcohol copolymer, polyvinyl methyl ether Polyethylene glycol, polypropylene glycol, polyoxyethylene / polyoxypropylene copolymer; amphoteric methacrylic acid such as (methacryloyloxyethylcarboxybetaine / alkyl methacrylate) copolymer, (acrylates / stearyl acrylate / ethylamine methacrylate oxide) copolymer, etc. Ester copolymer; (Dimethicone / vinyl dimethicone) crosspolymer, (alkyl acrylate / diacetone acrylamide) copolymer, (alkyl acrylate / diacetone acrylamide) copolymer AMP; Polyvinyl acetate partial saponification product, maleic acid copolymer; Vinylpyrrolidone / dialkylaminoalkyl methacrylate copolymer; acrylic resin alkanolamine; polyester, water-dispersible polyester; Kurylamide; Polyacrylic acid ester copolymer such as polyethyl acrylate, carboxyvinyl polymer, polyacrylic acid and its sodium salt, acrylic acid / methacrylic acid ester copolymer; acrylic acid / alkyl methacrylate Polymer: Cationized cellulose such as polyquaternium-10, diallyldimethylammonium chloride / acrylamide copolymer such as polyquaternium-7, acrylic acid / diallyldimethylammonium chloride copolymer such as polyquaternium-22, and acrylic acid such as polyquaternium-39・ Diallyldimethylammonium chloride / acrylamide copolymer, acrylic acid / cationized methacrylic acid ester copolymer, acrylic acid / cationized methacrylic acid amide copolymer, polyquaternium Acrylic acid / methyl acrylate / methacrylamidopropyltrimethylammonium chloride copolymer such as 47, methacrylic acid choline ester polymer; cationized polysaccharides such as cationized oligosaccharide, cationized dextran, guar hydroxypropyltrimonium chloride; Polyethyleneimine; Cationic polymer; Polymer of 2-methacryloyloxyethyl phosphorylcholine such as polyquaternium-51 and copolymer with butyl methacrylate copolymer; Acrylic resin emulsion, polyethyl acrylate emulsion, polyacrylalkyl ester emulsion, Polymer emulsions such as polyvinyl acetate resin emulsion, natural rubber latex, synthetic latex; nitrocellulose; polyurethanes and various copolymers; various silicones Various silicone-based copolymers such as acrylic-silicone graft copolymers; various fluoropolymers; 12-hydroxystearic acid and its salts; dextrin fatty acid esters such as dextrin palmitate and dextrin myristate; silicic anhydride, Smoke-like silica (ultrafine silicic anhydride), aluminum magnesium silicate, magnesium magnesium silicate, metal soap, dialkyl phosphate metal salt, bentonite, hectorite, organically modified clay mineral, sucrose fatty acid ester, fructooligosaccharide fatty acid ester It is mentioned as preferable.

  Solvents and propellants include ethanol, 2-propanol (isopropyl alcohol), butanol, isobutyl alcohol and other lower alcohols; propylene glycol, 1,3-butylene glycol, diethylene glycol, dipropylene glycol, isopentyl diol and other glycols Diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, triethylene glycol monoethyl ether, diethylene glycol diethyl ether, diethylene glycol dibutyl ether, propylene glycol monoethyl ether, dipropylene glycol monoethyl ether Glycol ethers such as ethylene glycol monoethyl ether Glycol ether esters such as acetate, diethylene glycol monoethyl ether acetate and propylene glycol monoethyl ether acetate; Glycol esters such as diethoxyethyl succinate and ethylene glycol disuccinate; benzyl alcohol, benzyloxyethanol, propylene carbonate, dialkyl carbonate , Acetone, ethyl acetate, N-methylpyrrolidone; toluene; fluorocarbon, next-generation flon; propellants such as LPG, dimethyl ether, carbon dioxide, and the like are preferable.

  Antioxidants include tocopherol derivatives such as tocopherol (vitamin E) and tocopherol acetate; BHT, BHA; gallic acid derivatives such as propyl gallate; vitamin C (ascorbic acid) and / or derivatives thereof; erythorbic acid and derivatives thereof; Preferred are sulfites such as sodium sulfite; bisulfites such as sodium bisulfite; thiosulfates such as sodium thiosulfate; metabisulfites; thiotaurine, hypotaurine; thioglycerol, thiourea, thioglycolic acid, cysteine hydrochloride As mentioned. Preferred examples of the reducing agent include thioglycolic acid, cysteine, cysteamine and the like. Preferred examples of the oxidizing agent include aqueous hydrogen peroxide, ammonium persulfate, sodium bromate, and percarbonate.

  Antibacterial agents or antiseptics include parabens (hydroxybenzoic acid esters) such as methylparaben, ethylparaben, propylparaben and butylparaben; phenoxyethanol; 1,2-pentanediol, 1,2-hexanediol, 1,2-octane 1,2-alkanediols such as diol; alkyl glyceryl ethers such as 2-ethylhexyl glyceryl ether (ethylhexyl glycerin); salicylic acid; sodium benzoate; isothiazoline derivatives such as methyl chloroisothiazolinone and methylisothiazolinone; Dehydroacetic acid and its salts; phenols; halogenated bisphenols such as triclosan, acid amides, quaternary ammonium salts; trichlorocarbanide, zinc pyrithione, benzoyl chloride Luconium, benzethonium chloride, sorbic acid, chlorhexidine, chlorhexidine gluconate, halocarban, hexachlorophene, hinokitiol; other phenols such as phenol, isopropylphenol, cresol, thymol, parachlorophenol, phenylphenol, sodium phenylphenol; phenylethyl alcohol , Photosensitizers, antibacterial zeolite, and silver ion are preferable, but when used as an antibacterial agent or antiseptic agent for antiseptic purposes, phenoxyethanol; 1 from the viewpoint of safety of cosmetics or skin external preparations; 1,2-alkanediols such as 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol; alkyl glyceres such as 2-ethylhexyl glyceryl ether It is more preferred to use ethers.

  Examples of chelating agents include edetate (ethylenediaminetetraacetate) such as EDTA, EDTA2Na, EDTA3Na, and EDTA4Na; hydroxyethylethylenediaminetriacetate such as HEDTA3Na; pentetate (diethylenetriaminepentaacetate); phytic acid; Phosphonic acid and its sodium salt; sodium oxalate; polypolyamino acids such as polyaspartic acid and polyglutamic acid; sodium polyphosphate, sodium metaphosphate, phosphoric acid; sodium citrate, citric acid, alanine, dihydroxyethylglycine Gluconic acid, ascorbic acid, succinic acid, and tartaric acid are preferable. pH adjusters / acids / alkalis include citric acid, sodium citrate, lactic acid, sodium lactate, glycolic acid, succinic acid, acetic acid, sodium acetate, malic acid, tartaric acid, fumaric acid, phosphoric acid, hydrochloric acid, sulfuric acid, monoethanol Amine, diethanolamine, triethanolamine, isopropanolamine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-hydroxymethyl-1,3-propanediol, arginine, hydroxylation Sodium, potassium hydroxide, aqueous ammonia, guanidine carbonate, and ammonium carbonate are preferable.

  Examples of powders include mica, talc, kaolin, sericite, montmorillonite, kaolinite, mica, muscovite, phlogopite, synthetic mica, red mica, biotite, permiculite, magnesium carbonate, calcium carbonate, aluminum silicate, silica Barium acid, calcium silicate, magnesium silicate, strontium silicate, metal tungstate, magnesium, zeolite, barium sulfate, calcined calcium sulfate, calcium phosphate, fluorine apatite, hydroxyapatite, ceramic powder, bentonite, smectite, clay, mud, Metal soap (e.g. zinc myristate, calcium palmitate, aluminum stearate), calcium carbonate, bengara, yellow iron oxide, black iron oxide, ultramarine, bitumen, carbon black, titanium oxide, fine particles and ultrafine Titanium oxide, zinc oxide, fine and ultrafine zinc oxide, alumina, silica, fumed silica (ultrafine silica), titanium mica, fish scale foil, boron nitride, photochromic pigment, synthetic fluorophlogopite, fine particle composite powder Body, gold, aluminum, etc., various sizes and shapes of inorganic powders, and these are treated with various surface treatment agents such as hydrogen silicone, cyclic hydrogen silicone, or other silane or titanium coupling agents Inorganic powders such as hydrophobized or hydrophilized powders; starch, cellulose, nylon powder, polyethylene powder, polymethyl methacrylate powder, polystyrene powder, copolymer resin powder of styrene and acrylic acid, polyester powder, Benzoguanamine resin powder, polyethylene terephthalate, polymethyl Organic powders and surface-treated powders of various sizes and shapes, such as methacrylate powder, polyethylene terephthalate / aluminum / epoxy powder, urethane powder, silicone powder, Teflon (registered trademark) powder, organic-inorganic composite powder Is preferable. Inorganic salts include sodium chloride-containing salts such as salt, common salt, rock salt, sea salt, natural salt; potassium chloride, aluminum chloride, calcium chloride, magnesium chloride, bittern, zinc chloride, ammonium chloride; sodium sulfate, aluminum sulfate, Aluminum sulfate / potassium sulfate (alum), aluminum sulfate / ammonium sulfate, barium sulfate, calcium sulfate, potassium sulfate, magnesium sulfate, zinc sulfate, iron sulfate, copper sulfate; sodium phosphates such as 1Na, 2Na and 3Na phosphates, phosphoric acid Potassium, calcium phosphates and magnesium phosphates are preferred.

  Vitamins and their derivatives include vitamin A such as retinol, retinol acetate, retinol palmitate; thiamine hydrochloride, thiamine sulfate, riboflavin, riboflavin acetate, pyridoxine hydrochloride, pyridoxine dioctanoate, pyridoxine dipalmitate, Flavin adenine dinucleotide, cyanocobalamin, folic acid, nicotinic acid such as nicotinic acid amide / benzyl nicotinate, vitamin B group such as choline; vitamin C such as ascorbic acid and its sodium salt; vitamin D; α, Vitamin Es such as β, γ, δ-tocopherol; other vitamins such as pantothenic acid and biotin; ascorbic acid phosphates such as ascorbic acid phosphate sodium salt and ascorbic acid phosphate magnesium salt; Ascorbic acid fatty acid esters such as corobic acid tetraisopalmitic acid ester, ascorbyl stearate, ascorbyl palmitate and ascorbyl dipalmitate, ascorbic acid alkyl ether such as ascorbic acid ethyl ether, ascorbic acid glucoside such as ascorbic acid-2-glucoside and Ascorbic acid derivatives such as fatty acid esters and tocopheryl phosphate ascorbyl; vitamin derivatives such as tocopherol nicotinate, tocopherol acetate, tocopherol acetate, tocopherol linoleate, tocopherol phosphate, tocopherol phosphate etc., tocotrienol, and other various vitamin derivatives Is preferable.

  Plant growth and tinctures such as assembly extract, red pepper tincture, ginger tincture, ginger extract, cantalis tincture; capsaicin, nonyl acid valenylamide, gingeron, ictamol, tannic acid Borneol, cyclandelate, cinnarizine, trazoline, acetylcholine, verapamil, cephalanthin, γ-oryzanol, cephalanthin, vitamin E and nicotinic acid tocopherol, acetic acid tocopherol and other derivatives, γ-oryzanol, nicotinic acid, nicotinic acid amide, nicotinic acid benzyl Derivatives such as ester, inositol hexanicotinate, nicotine alcohol, allantoin, photosensitizer 301, photosensitizer 401, capronium chloride, pentadecanoic acid monoglyceride, Preferable examples include flavonol derivatives, stigmasterol or stigmasteranol, its glycosides, and minoxidil.

  As plant / animal / microbe extracts, Iris extract, Ashitaba extract, Asunaro extract, Asparagus extract, Avocado extract, Achacha extract, Almond extract, Altea extract, Arnica extract, Aloe extract, Apricot extract, Ginkgo biloba extract, Ginkgo biloba extract , Incheon extract, Fennel extract, Turmeric extract, Oolong tea extract, Peony extract, Ages extract, Echinacea leaf extract, Enmeo extract, Ogon extract, Oat extract, Auren extract, Barley extract, Panax ginseng extract, Hypericum extract, Odori extract , Dutch mustard extract, orange extract, dried sea water, seaweed extract, oyster leaf extract, oyster extract, hydrolyzed elastin, hydrolyzed wheat powder, hydrolysis Luc, Cascon extract, Chamomile extract, Oil-soluble chamomile extract, Carrot extract, Kawara mugi extract, Oat extract, Calcade extract, Licorice extract, Oil-soluble Licorice extract, Kiwi extract, Kiou extract, Cyprid extract, Quina extract, Cucumber extract, Kiri leaf extract, Guanosine, guava extract, cucumber extract, gardenia extract, kumazasa extract, clara extract, walnut extract, chestnut extract, grapefruit extract, clematis extract, black rice extract, brown sugar extract, black vinegar, chlorella extract, mulberry extract, gentian extract, Gentian pepper extract, tea Extract, yeast extract, kokuboku extract, coffee extract, burdock extract, rice extract, rice fermented extract, rice bran fermented extract, rice germ oil, comfrey extract, Lagen, Cowberry extract, Saishin extract, Psycho extract, Saitai extract, Saffron extract, Salvia extract, Salmon extract, Sasa extract, Hawthorn extract, Sansha extract, Salamander extract, Shiitake extract, Giant extract, Shikon extract, Perilla extract, Linden extract, Shimosukeso Extract, jatoba extract, peonies extract, ginger cucumber extract, ginger root extract, white birch extract, white jellyfish extract, horsetail extract, stevia extract, stevia fermented product, west river willow extract, horse chestnut extract, hawthorn extract, elderberry extract, yarrow extract , Mint extract, sage extract, mallow extract, nematode extract, essence extract, Sakuhakuhi extract, Diou extract, Dai Extract, peanut extract, thyme extract, dandelion extract, lichen extract, tea extract, clove extract, chigaya extract, chimpi extract, tea tree oil, tea tea extract, red pepper extract, red snapper extract, red snapper extract, red spruce extract, red spruce extract, tomato Extract, natto extract, carrot extract, garlic extract, wild rose extract, hibiscus extract, bacmond extract, lotus extract, parsley extract, birch extract, honey, hamamelis extract, parietalia extract, hyacinth extract, bisabolol, cypress extract, bifidobacteria extract, Loquat extract, dandelion extract, burdock extract, bukkuri extract, butcher bloom extract, grape extract, grape seed extract, propolis, loofah extract, Safflower extract, peppermint extract, body extract, button extract, hop extract, squid extract, pine extract, maroonnier extract, mizubasho extract, mukuroji extract, melissa extract, mozuku extract, peach extract, cornflower extract, eucalyptus extract, yukinoshita extract, yuzu extract, lily extract, Yokuinin extract, mugwort extract, lavender extract, green tea extract, eggshell membrane extract, apple extract, rooibos tea extract, litchi extract, lettuce extract, lemon extract, forsythia extract, forsythia extract, rose extract, rosemary extract, roman chamomile extract, royal jelly Extracts such as an extract and a bitumen extract are preferred.

As perfumes, acetyl cedrene, amylcinnamaldehyde, allyl amyl glycolate, β-ionone, iso-Esuper, isobutyl quinoline, Iris oil, Iron, indole, ylang ylang oil, undecanal, undecenal, γ-undecalactone, Estragole, eugenol, oak moss, opoponax resinoid, orange oil, eugenol, auranthiol, galac solid, carvacrol, L-carvone, camphor, cannon, carrot seed oil, clove oil, methyl cinnamate, geraniol, geranyl nitrile , Isobornyl acetate, geranyl acetate, dimethylbenzyl carvinyl acetate, styrylyl acetate, cedolyl acetate, terpinel acetate, pt-butylcyclohexyl acetate, vetiberyl acetate, benzyl acetate, acetic acid Linalyl, isopentyl salicylate, benzyl salicylate, sandalwood oil, santalol, cyclamenaldehyde, cyclopentadecanolide, methyl dihydrojasmonate, dihydromilsenol, jasmine absolute, jasmine lactone, cis-jasmon, citral, citronenol, citronellal, Cinnamon bark oil, 1,8-cineole, cinnamaldehyde, stylax resinoid, cedarwood oil, cedrene, cedrol, celery seed oil, thyme oil, damascon, damacenone, thymol, tuberose absolute, decanal, decalactone, terpineol, γ-terpinene, Tripral, Nellore, Nonanal, 2,6-Nonadienol, Nonalactone, Patchouli alcohol, Vanilla absolute Vanillin, basil oil, patchouli oil, hydroxycitronellal, α-pinene, piperitone, phenethyl alcohol, phenylacetaldehyde, petitglen oil, hexylcinnamaldehyde, cis-3-hexenol, perubalsum, vetiver oil, vetiverol, peppermint oil, pepper Oil, heliotropin, red 223, red 225, red 226, red 227, red 228, red 230-1, red 230-2, red 231, red 232, red 3, red 401, Red 404, Red 405, Red 501, Red 502, Red 503, Red 504, Red 505, Red 506, Orange 201, Orange 203, Orange 204, Orange 205 Orange 206, orange 207, orange 401, orange 402, orange 403 No., yellow 201, yellow 202-1, yellow 202-2, yellow 203, yellow 204, yellow 205, yellow 4, yellow 401, yellow 402, yellow 403-1, yellow 404 , Yellow 405, Yellow 406, Yellow 407, Yellow 5 and other legal dyes; Acid Red 14 and other acidic dyes; Arianor Sienna Brown, Arianor Madder Red, Arianor Steel Blue, Arianor Straw Yellow and other basic dyes HC Yellow 2, HC Yellow 5, HC Red 3, 4-hydoxypropylamino-3-nitrophenol, N, N'-bis (2-hydroxyethyl) -2-nitro-p-
phenylenediamine, HC Blue 2, Basic
Nitro dyes such as Blue 26; Disperse dyes; Inorganic white pigments such as titanium dioxide and zinc oxide; Inorganic red pigments such as iron oxide (Bengara) and iron titanate; Inorganic brown pigments such as γ-iron oxide; Yellow oxidation Inorganic yellow pigments such as iron and ocher; inorganic black pigments such as black iron oxide and low-order titanium oxide; inorganic purple pigments such as mango violet and cobalt violet; inorganic such as chromium oxide, chromium hydroxide and cobalt titanate Green pigments; inorganic blue pigments such as ultramarine and bitumen; pearl pigments such as titanium oxide coated mica, titanium oxide coated bismuth oxychloride, titanium oxide coated talc, colored titanium oxide coated mica, bismuth oxychloride, fish scale foil; aluminum powder Metal powder pigments such as copper powder and gold; surface-treated inorganic and metal powder pigments; red 201, red 202, Color No. 204, Red No. 205, Red No. 220, Red No. 226, Red No. 228, Red No. 405, Orange No. 203, Orange No. 204, Yellow No. 205, Yellow No. 401, Blue No. 404, Red No. 3, Red 104 No., Red No. 106, Red No. 227, Red No. 230, Red No. 401, Red No. 505, Orange No. 205, Yellow No. 4, Yellow No. 5, Yellow No. 202, Yellow No. 203, Green No. 3, Blue No. 1, etc. Organic pigments such as zirconium, barium or aluminum lakes; surface-treated organic pigments; anthraquinones such as astaxanthin and alizarin, anthocyanidins, β-carotene, catenal, capsanthin, chalcone, calsamine, quercetin, crocin, chlorophyll, curcumin, cochineal, shikonin Naphthoquinones, bixins, flavones, betacyanidine, Natural pigments / dyes such as hemoglobin, lycopene, riboflavin, rutin; p-phenylenediamine, toluene-2,5-diamine, o-, m-, or p-aminophenol, m-phenylenediamine, 5-amino-2 -Oxidative dye intermediates and couplers such as methylphenol, resorcin, 1-naphthol, 2,6-diaminopyridine, and salts thereof; auto-oxidizing dyes such as indoline; and dihydroxyacetone are preferred.

  Preferred examples of water include normal water, purified water, hard water, soft water, natural water, deep sea water, electrolytic alkaline ionized water, electrolytic acidic ionized water, ionic water, and clustered water.

  In addition to these, cosmetic raw material standards, blending ingredient standard by cosmetic varieties, Japan Cosmetic Industry Association ingredient display name list, INCI dictionary (The International Cosmetic Ingredient Dictionary and Handbook), quasi-drug raw material standards, Japanese pharmacopoeia, pharmaceutical additives Ingredients listed in standards, official food additives, etc., and Japanese and foreign patent publications and patent publications (including publications and republications) in which the international patent classification IPC belongs to the classification of A61K7 and A61K8 It is possible to contain known cosmetic ingredients, pharmaceutical ingredients, food ingredients, etc., such as the ingredients described, in known combinations, blending ratios and blending amounts.

  The types of hair cosmetics of the present invention will be described in more detail. Oil shampoo, cream shampoo, conditioning shampoo, dandruff shampoo, hair color shampoo, shampoo with integrated rinse, etc .; rinse, treatment, hair pack, hair foam , Hair mousse, hair spray, hair mist, hair wax, hair gel, water grease, set lotion, color lotion, hair tonic, hair liquid, pomade, tic, hair cream, hair blow, split hair coat, hair oil, permanent wave agent, straight perm Agent, oxidation hair dye, hair bleach, hair color pretreatment, hair color after treatment, perm pretreatment, perm after treatment, hair manicure , It is mentioned as hair growth agents are preferred.

  As the dosage form of the hair cosmetic of the present invention, emulsified cosmetics such as oil-in-water (O / W) type, water-in-oil (W / O) type, W / O / W type, O / W / O type, etc. Oily cosmetics, solid cosmetics, liquid cosmetics, kneaded cosmetics, stick cosmetics, volatile oil cosmetics, powder cosmetics, jelly cosmetics, gel cosmetics, paste cosmetics, Preferred examples include emulsion polymer cosmetics, sheet cosmetics, mist cosmetics, and spray cosmetics.

  The method for improving hair elasticity of the present invention is characterized in that a hair elasticity improving agent containing a lactone derivative represented by the general formula (1) is applied to the hair and subjected to heat treatment. For the heat treatment, a hair iron, a trowel, a digital permanent, a dryer or the like can be used. Heat treatment conditions are about 1 to 10 times at a set temperature of 60 to 180 ° C. for hair irons and irons, about 1 to 60 minutes at 60 to 120 ° C. for digital perms, and hot air for dryers 30 What is necessary is just to process for about 10 minutes for second. By performing the heat treatment, the hair can be given elasticity and the effect can be maintained.

EXAMPLES Hereinafter, although this invention is demonstrated in detail using an Example, this invention is not limited to these Examples. In this example, the infrared absorption spectrum was measured using IRAffinity-1 manufactured by Shimadzu Corporation. The ¹ H-NMR spectrum was measured using JNM-AL (300 MHz) manufactured by JEOL Ltd. and deuterated methanol as a solvent.

Synthesis Example 1 Synthesis of γ-ercalactone (4-hydroxydocosanoic acid γ-lactone) In a 200 mL reactor equipped with a stirrer, a thermometer, and a gas introduction tube, 16.9 g (0.0500 mol) of erucic acid, 10.1 g (0.100 mol) of sulfuric acid was charged and reacted at 85 ° C. for 6 hours under a nitrogen atmosphere. The obtained reaction solution was charged with 50 g of water, 118 g of heptane, 4% sodium hydroxide, the target product was extracted into a heptane phase, deoxidized with 2% sodium hydroxide solution, and washed with water three times. The heptane phase was concentrated under reduced pressure to obtain 3.4 g of the objective compound as a solid. The obtained solid was a white solid (infrared absorption spectrum (KBr tablet method): 2918, 2851, 1753, 1468, 1188 cm ⁻¹ ). It was subjected to structural confirmed by ^{1 H-NMR} spectrum for the compound was confirmed to be a compound represented by the following general formula (assignment numbers of the ^{1 H-NMR} spectrum in the formula, attribution Table 1 Showing).

Synthesis Example 2 Synthesis of γ-stearolactone (4-hydroxyoctadecanoic acid γ-lactone) To a 200 mL reactor equipped with a stirrer, a thermometer, and a gas introduction tube, oleic acid (trade name, LUNAC O-LL, manufactured by Kao Corporation) was prepared. -V) 14.1 g (0.0500 mol) of concentrated sulfuric acid and 10.1 g (0.100 mol) of concentrated sulfuric acid were charged and reacted at 85 ° C. for 6 hours in a nitrogen atmosphere. 50 g of water, 99 g of heptane, and 4% sodium hydroxide were charged into the resulting reaction solution, and the target product was extracted into a heptane phase. After deoxidation with 2% sodium hydroxide solution, washing with water was performed three times. The heptane phase was concentrated under reduced pressure to obtain 2.6 g of the objective compound as a solid. The obtained solid was a white solid (infrared absorption spectrum (KBr tablet method) 2920, 2851, 1753, 1470, 1190 cm ⁻¹ ). It was subjected to structural confirmed by ^{1 H-NMR} spectrum for the compound was confirmed to be a compound represented by the following general formula (assignment numbers of the ^{1 H-NMR} spectrum in the formula, attribution Table 2 Showing).

  A hair cosmetic was prepared with the composition shown in Table 3 and blended with Synthesis Example 1, Synthesis Example 2, or δ-tetradecanolactone (manufactured by Wako Pure Chemical Industries, Ltd.), which is a lactone derivative used in the present invention (Examples). 1-3). For comparison, a hair cosmetic containing no lactone derivative was prepared (Comparative Example 1).

（調製方法）
Ａ部を約８０℃で攪拌混合した。別途８０℃に加温したＢ部にＡ部を加え、ホモミキサーを用いて攪拌（８０００ｒｐｍ、３０分）後、室温まで冷却した。

(Preparation method)
Part A was stirred and mixed at about 80 ° C. A part was added to B part separately heated at 80 degreeC, and it stirred (8000 rpm, 30 minutes) using the homomixer, and cooled to room temperature.

Harikoshi improvement effect (sensory evaluation)
Using the hair cosmetics of Examples 1 to 3 and Comparative Example 1 described above, the effect of improving the firmness of the hair was evaluated. The test method was performed as follows. The results are shown in Table 4.

(Test method)
A healthy black-haired human hair was bleached once with a commercially available bleaching agent to prepare a hair bundle of damaged hair. Next, 1 g of the hair cosmetic composition of Example 1 was uniformly applied to 5 g of the damaged hair bundle and air-dried to obtain a hair bundle A1. A part of the hair bundle A1 was heat-treated with warm air from a dryer for 3 minutes to obtain a hair bundle B1. Further, a part of the hair bundle B1 was further washed with a 3% aqueous solution of sodium laureth sulfate and washed with water five times, and then air-dried to obtain a hair bundle C1. Similarly, the hair bundle A2-C2 using the hair cosmetic composition of Example 2, the hair bundle A3-C3 using the hair cosmetic composition of Example 3, and the hair bundle using the hair cosmetic composition of Comparative Example 1 A4 to C4 were prepared. About each produced hair bundle, the sharpness improvement effect of the hair was evaluated by sensory evaluation (7 panelists).

  From the results of Table 4, it was found that in the hair cosmetics of Examples 1 to 3 in which the hair sharpener of the present invention was blended, the hair sharpness was improved. In particular, it was found that heat treatment significantly improved the sharpness of the hair and the effect persisted even after repeated washing.

Sharpening effect (pure bending test)
A pure bending test was performed on the hair bundle (B1) treated with the hair cosmetic of Example 1 used in the above sensory evaluation test and the hair bundle before treatment with the hair cosmetic as a comparison, and bending stiffness (B ) And bend recovery (2HB) were measured, and the effect of improving sharpness was evaluated. The flexural rigidity (B) is an index of hardness / softness felt when a person bends an object, and indicates that the greater the value, the harder it is. Bending recovery (2HB) is an index of recovery (elasticity) felt when a person bends and returns an object, and the smaller the value, the better the recovery (elasticity). The measurement method was performed as follows, and the results are shown in Table 5.

(Test method)
50 hairs were arranged in parallel at intervals of 5 cm, and both ends thereof were fixed to a fixed chuck and a moving chuck of a hair strain tester (KES-FB2-S-DC Kato Tech Co., Ltd.). The sample size was set to 5 cm, the curvature (k) was changed from 0 to 1.0 at a constant speed, and the bending moment (M) was measured (measurement was reciprocated). The measurement was performed three times, and the average value was used as the result. The bending stiffness (B) was calculated from the slope of the straight line obtained by the proportional relationship between the measured bending moment (M) and the curvature (k). In addition, a difference in bending moment (M) at a curvature of 0.5 was obtained from a hysteresis curve measured by reciprocating, and bending recovery (2HB) was calculated.

From the results shown in Table 5, the hair bundle treated with the hair cosmetic composition of Example 1 has no change in bend recovery before and after the treatment, but the bending stiffness is increased, and the hair stiffness is improved. I understood. It was considered that this gave the hair a sense of elasticity.

Reactivity Evaluation with Amino Group The γ-ercalactone of Synthesis Example 1 was tested for reactivity with an amino group. The test was performed as follows, and the results are shown in Table 6.

(Test method)
10 mg (0.037 mmol) of stearylamine, 8.4 mg (0.025 mmol) of the compound of Synthesis Example 1 and 100 μL of cyclohexane were uniformly dissolved in a test tube, and each of 60 ° C., 80 ° C. and 120 ° C. was obtained with a block heater. Heated at temperature for 15 minutes. Then it dried without the temperature at reduced pressure and the resulting residue was measuring the infrared absorption spectrum (KBr tablet method) for the peak in the vicinity of 1635 cm ^-1 derived from the peak and amides of around 1750 cm ^-1 derived from lactone The presence or absence was confirmed.

  From the results in Table 6, it was found that the γ-lactone derivative of the present invention was heated with an amine compound to generate an amide peak and the lactone peak disappeared. That is, it was found that the γ-lactone derivative of the present invention readily reacts with an amino group at a temperature of about 60 ° C. to form an amide bond.

Evaluation of reactivity with hair Using the γ-ercalactone of Synthesis Example 1, the reactivity with hair was tested. The test was performed as follows, and the results are shown in Table 7.

(Test method)
Healthy black hair human hair was treated once with a commercial bleaching agent to produce a bundle of damaged hair. 0.2 g of a 1% ethanol solution of a γ-ercalactone compound was uniformly applied to 1 g of the damaged hair bundle, and air-dried. About the obtained hair bundle, using a hair iron (trade name Allure, manufactured by Izumi Seiki Seisakusho Co., Ltd.), using an attachment as a straight type, heat treatment for 30 seconds was performed twice at each temperature of 80 ° C., 100 ° C., and 120 ° C. did. With respect to the hair bundle before and after the heat treatment, an infrared absorption spectrum (ATR method) was measured to confirm the presence or absence of a peak near 1750 cm ⁻¹ derived from a lactone. In the hair bundle before applying γ-ercalactone, no lactone peak was observed.

From the results shown in Table 7, it was confirmed that the lactone peak disappeared by applying the γ-lactone derivative of the present invention to the hair and applying heat treatment. Since protein-derived amide bonds exist in hair, the formation of amide bonds due to the reaction could not be confirmed in the infrared absorption spectrum, but the disappearance of the lactone constitutes the hair from the result of the reactivity with the amino group. This is presumably due to a reaction with an amino group contained in the amino acid residue of the protein. That is, the γ-lactone derivative of the present invention is chemically bonded to the hair by applying it to the hair and applying heat treatment. This is why the improvement effect was not lost.

Example 4 Hair mist Hair mist having the following formulation was prepared. This hair mist was not sticky and gave a good feel and smooth fingering that was smooth to the hair, and gave the hair a firmness.

Component Blending amount (wt%)
-----------------------------------
γ-ercalactone 0.10
SUCRAPH AG-8 (Nippon Seika) 0.30
Dimethicone 0.10
Cetrimonium chloride (30%) 6.00
Ethanol 8.00
Purified water Total amount of 100 -----------------------------------
(Preparation method)
Each component was stirred and mixed uniformly.

Example 5 Hair Essence A hair essence having the following formulation was prepared. This hair essence has a refreshing feel, is not sticky, can impart moisture and a feeling of slipping, and gives hair a firmness.

Component Blending amount (% by weight)
-----------------------------------
Part A δ-tetradecanolactone 0.20
Cyclohexane-1,4-dicarboxylic acid bisethoxydiglycol 1.00
Cetanol 1.00
Steartrimonium chloride (63%) 0.80
Dicocodimonium chloride (75%) 2.80
Tetraoleic acid Solves-60 1.00
PEG-40 hydrogenated castor oil 0.20
Part B methylparaben 0.10
Purified water Total amount of 100 -----------------------------------
(Preparation method)
Part A was heated to about 80 ° C. and dissolved. Part B was taken in another container and dissolved by heating to about 80 ° C. Part B was gradually added to part A and mixed uniformly.

Example 6 Hair Lotion A hair lotion having the following formulation was prepared. By applying this hair lotion, the refreshing feeling of menthol was maintained, the scalp was kept healthy, and the hair was irritated.

Component Blending amount (wt%)
-----------------------------------
Part A δ-tetradecanolactone 0.20
PEG-4 3.00
Menthol 0.05
Ethanol 50.0
Part B pyridoxine HCl 0.10
Glycyrrhizic acid 2K 0.10
BG 3.00
Panthenol 2.00
Purified water Total amount of 100 -----------------------------------
(Preparation method)
A part Each component is mixed (A part). B part Each component is mixed (B part). Add part B to part A and mix evenly.

Example 7 Restoration of bedclothes A bedclothing of the following formulation was prepared. This re-laying was applied to the hair, so that slipping and cohesion improved moist feeling and gave the hair a firmness.

Component Blending amount (wt%)
-----------------------------------
δ-tetradecanolactone 0.80
N-methylpyrrolidone 2.00
Glycerin 2.00
Pentylene glycol 2.00
Behentrimonium chloride (80%) 0.60
Ethanol 20.0
Dimethicone propyl betaine 1.00
Purified water Total amount of 100 -----------------------------------
(Preparation method)
Dissolve all ingredients uniformly.

Example 8 Hair Cream A hair cream having the following formulation was prepared. This hair cream was glossy, non-sticky, kept the moisture of the hair, gave a smooth feel, and gave the hair a firm feeling.

Component Blending amount (wt%)
-----------------------------------
Part A γ-ercalactone 10.00
Cetanol 4.00
Dimethicone (500cs) 5.00
Glyceryl stearate 2.80
Ores-10 phosphate 0.80
Glyceryl stearate (SE) 1.60
B part phenoxyethanol 0.40
Methylparaben 0.20
10% NaOH 0.60
Purified water Total amount of 100 -----------------------------------
(Preparation method)
Part A was heated to about 80 ° C. and dissolved. Part B was added to a separate container, heated to about 80 ° C. and dissolved. Part B was added to part A and mixed with stirring.

Example 9 Non-washing hair treatment A non-washing hair treatment of the following formulation was prepared. This hair treatment was intended to improve the elasticity by slipping, cohering, fingering and moisturizing the hair.

Component Blending amount (wt%)
------------------------------------
Part A γ-stearolactone 0.50
Cyclohexane-1,4-dicarboxylic acid bisethoxydiglycol 2.00
Cetrimonium chloride (25%) 3.80
Caprylyl glucoside (50%) 0.80
Glycerin 4.00
Phenoxyethanol 0.20
Part B ethanol 20.00
Part C Polyquaternium-6 0.60
Polyquaternium-7 0.40
White jellyfish polysaccharide 0.05
Purified water Total amount of 100 -------------------------------------
(Preparation method)
Part C was heated to about 80 ° C. and dissolved. Next, part A was heated to about 80 ° C. and dissolved. Part A was added with stirring, part A was mixed uniformly, and then cooled to about 40 ° C. Next, part B was added and mixed uniformly.

Example 10 Leave-on treatment A leave-on treatment (for hair) having the following formulation was prepared. This leave-on treatment (for hair) imparted a good feel that was moist and slippery, and gave a firmness. Moreover, stability was also favorable.

Component Blending amount (% by weight)
------------------------------------
Part A γ-ercalactone 6.00
Diethyl sebacate 1.00
Myristyl alcohol 5.00
Behenyl alcohol 1.00
Oleyl alcohol 1.00
Stearic acid dimethylpropylamide 2.00
Cocoamphoacetate Na (30%) 2.00
Glyceryl stearate 0.40
Myristic acid 0.60
Phenoxyethanol 0.40
Part B lactic acid 0.60
Purified water Total amount of 100 ------------------------------------
(Preparation method)
Part A was heated to about 80 ° C. and dissolved uniformly. Part B was heated to about 80 ° C. and dissolved. Part B was gradually added to part A and mixed uniformly.

Example 11 Leave-on treatment A leave-on treatment (for hair) having the following formulation was prepared. This leave-on treatment (for hair) imparted a moist and good feel to the hair and gave it a firmness. Moreover, stability was also favorable.

Component Blending amount (wt%)
-----------------------------------
Part A γ-stearolactone 2.50
Isopropyl palmitate 4.00
Cetanol 5.00
Steartrimonium chloride (63%) 3.20
Behentrimonium chloride (80%) 1.00
Squalane 1.00
Glycerin 1.00

Part B methylparaben 0.10
Purified water Total amount of 100 -----------------------------------
(Preparation method)
Part A was heated to about 80 ° C. and dissolved. Part B was heated to about 80 ° C. and dissolved. Part B was gradually added to part A and mixed uniformly.

Claims (3)

A hair sharpening agent containing a lactone derivative represented by the following general formula (1).

(In the formula, n is 1 or 2, and R represents a linear or branched saturated or unsaturated hydrocarbon group having 9 to 22 carbon atoms)   A hair cosmetic composition for improving sharpness, wherein the sharpening agent according to claim 1 is blended.   A method for improving hair elasticity, comprising applying the agent for improving sharpness according to claim 1 to hair and performing heat treatment.